Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing

Li, Qingyun, Cheng, Zuolin, Zhou, Lu, Darmanis, Spyros, Neff, Norma F., Okamoto, Jennifer, Gulati, Gunsagar, Bennett, Mariko L. +7 more·2019·Neuron

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  24. Do Microglial Sex Differences Contribute to Sex Differences in Neurodegenerative Diseases?
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  41. Macrophagic and microglial complexity after neuronal injury
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  45. Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation
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    Vanessa M. Puñal, Caitlin E. Paisley, Federica S. Brecha, Monica A. Lee, Robin M. Perelli, Jingjing Wang, Emily G. O’Koren, Caroline R. Ackley, Daniel R. Saban, Benjamin E. Reese et al. · 2019 · PLoS Biology
  47. Microglia in brain development and regeneration
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    Arthur A. Vandenbark, Halina Offner, Szymon Matejuk, Agata Matejuk · 2021 · Journal of Neuroinflammation
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    Jean Paul Chadarevian, Sonia I Lombroso, Graham C. Peet, Jonathan Hasselmann, Christina H. Tu, Dave E. Marzan, Joia Kai Capocchi, Freddy S Purnell, Kelsey Marie Nemec, Alina Lahian et al. · 2022 · The Journal of Experimental Medicine
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  62. Gene expression profiling reveals a conserved microglia signature in larval zebrafish
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  65. Microglia heterogeneity, modeling and cell-state annotation in development and neurodegeneration
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  67. Noteworthy perspectives on microglia in neuropsychiatric disorders
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  69. Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities
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  71. Human neuronal maturation comes of age: cellular mechanisms and species differences
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  72. Microglia and sexual differentiation of the developing brain: A focus on extrinsic factors
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  76. Microglia transcriptional states and their functional significance: Context drives diversity
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  77. Spatial dynamics of brain development and neuroinflammation
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  78. Microglia as Therapeutic Target for Radiation-Induced Brain Injury
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  79. Early life stress impairs synaptic pruning in the developing hippocampus
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  80. Different phenotypes of microglia in animal models of Alzheimer disease
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  81. Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain
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  82. Early-life stress lastingly impacts microglial transcriptome and function under basal and immune-challenged conditions
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  83. Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy
    Kempthorne, Liam, Yoon, Hyejin, Madore, Charlotte, Smith, Scott, Wszolek, Zbigniew K., Rademakers, Rosa, Kim, Jungsu, Butovsky, Oleg, Dickson, Dennis W. · 2020 · Acta Neuropathologica Communications
  84. Selective inhibition of mitochondrial respiratory complexes controls the transition of microglia into a neurotoxic phenotype in situ
    Bruno Chausse, Andrea Lewen, Gernot Poschet, Oliver Kann · 2020 · Brain Behavior and Immunity
  85. Common cell type nomenclature for the mammalian brain
    Jeremy A. Miller, Nathan W. Gouwens, Bosiljka Tasic, Forrest Collman, Cindy T. J. van Velthoven, Trygve E. Bakken, Michael Hawrylycz, Hongkui Zeng, Ed S. Lein, Amy Bernard · 2020 · eLife
  86. A RIPK1-regulated inflammatory microglial state in amyotrophic lateral sclerosis
    Lauren Mifflin, Zhirui Hu, Connor Dufort, Cynthia C. Hession, Alec J. Walker, Kongyan Niu, Hong Zhu, Nan Liu, Jun S. Liu, Joshua Z. Levin et al. · 2021 · Proceedings of the National Academy of Sciences
  87. Sirtuin 5 aggravates microglia-induced neuroinflammation following ischaemic stroke by modulating the desuccinylation of Annexin-A1
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  88. Microglial diversity in neuropathic pain
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  89. Single-cell RNA-seq clustering: datasets, models, and algorithms
    Lihong Peng, Xiongfei Tian, Geng Tian, Junlin Xu, Xin Huang, Yanbin Weng, Jialiang Yang, Liqian Zhou · 2020 · RNA Biology
  90. Microglia dynamics in sleep/wake states and in response to sleep loss
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  91. CCR2 deficiency alters activation of microglia subsets in traumatic brain injury
    Kerri Somebang, Joshua D. Rudolph, Isabella Imhof, Luyi Li, Eréne C. Niemi, Judy K. Shigenaga, Huy Tran, Thomas M. Gill, Iris Lo, Brian A. Zabel et al. · 2021 · Cell Reports
  92. Beneficial and detrimental functions of microglia during viral encephalitis
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  93. Human microglia maturation is underpinned by specific gene regulatory networks
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  94. Border-associated macrophages as gatekeepers of brain homeostasis and immunity
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  95. More than meets the eye: The role of microglia in healthy and diseased retina
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  97. Shifting equilibriums in Alzheimer’s disease: the complex roles of microglia in neuroinflammation, neuronal survival and neurogenesis
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