Overcoming addiction stigma: Epigenetic contributions to substance use disorders and opportunities for intervention
Open accessAbstract
Substance use disorders (SUDs) are frequently stigmatized by society. However, overcoming stigmas to effectively treat SUDs requires acknowledging the developmental path of neural vulnerability. These vulnerabilities begin long before adulthood, providing opportunities to change the trajectory before the disorder becomes entrenched. This article raises attention to reversible epigenetic underpinnings of this vulnerability.
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Public attitudes toward individuals with addiction remain markedly negative, often more so than toward those with other mental health conditions.
“Public attitudes toward individuals with addiction remain markedly negative, often more so than attitudes toward those with other mental health conditions.”
From Beyond Stigma–Integrating Neurobiology, Genetics, and Awareness Integration Theory in Addiction Recovery (2026) · cites this paper as [91]
Cites
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Blum, K., Gold, M., Jafari, N., Lewandrowski, K.-U., Sharafshah, A., Mohankumar, K., Lorio, M., Bowirrat, A., Pinhasov, A., Thanos, K., et al. (2026) · Psychology Research and Behavior Management · doi:10.2147/prbm.s561157 · Cited by 1 · see citing works
- Authors
- Szutorisz, H., & Hurd, Y. L.
- Affiliations
- Icahn School of Medicine at Mount Sinai (US)
- Corresponding author
- Hurd, Yasmin L.
- ORCID
- Hurd, Yasmin L.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2022-05
- Volume
- 110
- Issue
- 10
- Pages
- 1611-1614
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W4223512840
- Cited by
- 9
- References
- 13
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 4 · 2022: 1
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 382 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Drug Abuse
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Epigenetics and DNA Methylation
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- addiction stigma, substance use disorders, epigenetics, addiction treatment, early intervention
- MeSH terms
- Adult, Humans, Behavior, Addictive, Substance-Related Disorders, Epigenesis, Genetic, Social Stigma
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