Cited by 126Cerebrovascular and genetic disordersDementia and Cognitive Impairment ResearchNeural and Behavioral Psychology Studies

The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.

White matter hyperintensities and within-person variability in community-dwelling adults aged 60–64 years

BUNCE, D, ANSTEY, K, CHRISTENSEN, H, DEAR, K, WEN, W, SACHDEV, P·2007·Neuropsychologia

Abstract

Estimates of white matter hyperintensities (WMH) derived from T2-weighted MRI were investigated in relation to cognitive performance in 469 healthy community-dwelling adults aged 60-64 years. Frontal lobe WMH but not WMH from other brain regions (temporal, parietal, and occipital lobes, anterior and posterior horn, periventricular body) were associated with elevated within-person reaction time (RT) variability (trial to trial fluctuations in RT performance) but not performance on several other cognitive tasks including psychomotor speed, memory, and global cognition. The findings are consistent with the view that elevated within-person variability is related to neurobiological disturbance, and that attentional mechanisms supported by the frontal cortex play a key role in this type of variability.

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Crossref · 10.1016/j.neuropsychologia.2007.02.006

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40 of 40 references verified0 citation errors · 0 not checkable

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  • Reaction time variability is associated with a higher proportion of white matter hyperintensities across frontal regions.

    “Finally, RTV has been associated with a higher proportion of white matter hyperintensities (i.e., small regions of high intensity observed on magnetic resonance imaging) across the frontal regions [61].”

    From Reaction Time Variability in ADHD: A Review (2012) · cites this paper as [61]

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Metadata

Authors
BUNCE, D., ANSTEY, K., CHRISTENSEN, H., DEAR, K., WEN, W., & SACHDEV, P.
Affiliations
  • Brunel University of London (GB)
  • Australian National University (AU)
  • UNSW Sydney (AU)
Corresponding author
BUNCE, D
Venue
Neuropsychologia
Publisher
Elsevier BV
Published
2007
Volume
45
Issue
9
Pages
2009-2015
ISSN
0028-3932 (ISSN-L)
OpenAlex
W2011352093
Cited by
126
References
40
Citations by year
2025: 6 · 2024: 4 · 2023: 7 · 2022: 5 · 2021: 3 · 2020: 3 · 2019: 5 · 2018: 5 · 2017: 8 · 2016: 7 · 2015: 12 · 2014: 8 · 2013: 11 · 2012: 9
FWCI
5.30
Type
journal article
Language
en
Open access
closed
Locations
  • Neuropsychologia (publishedVersion)
  • PubMed (publishedVersion)
  • Brunel University Research Archive (BURA) (Brunel University London) (submittedVersion)
  • ANU Open Research (Australian National University) (submittedVersion)
Topics
  • Health Sciences › Medicine › Clinical Neurology › Cerebrovascular and genetic disorders
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords
white matter hyperintensities, within-person variability, reaction time variability, frontal lobe, cognitive performance, attention, older adults, community-dwelling adults, T2-weighted MRI, psychomotor speed, memory
MeSH terms
Attention, Brain Mapping, Cognition, Female, Frontal Lobe, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Neuropsychological Tests, Psychomotor Performance, Reaction Time, Regression Analysis, Residence Characteristics

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