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Pik3c3 deletion in pyramidal neurons results in loss of synapses, extensive gliosis and progressive neurodegeneration
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“Chronic defects in PI(3)P synthesis are linked to reductions in dendritic spine density, reactive gliosis, and progressive neurodegeneration”
From PI(3)P coordinates SNX17- and SNX27-dependent protein recycling for long-term synaptic plasticity (2025) · cites this paper as Wang et al., 2011
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“In neurons, PI(3)P is widely distributed in both dendrites and axons, with an enrichment at synapses, where it co-localizes with the postsynaptic scaffold PSD95”
From PI(3)P coordinates SNX17- and SNX27-dependent protein recycling for long-term synaptic plasticity (2025) · cites this paper as Wang et al., 2011
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BackgroundBDNF activates mTOR to regulate GluR1 expression required for memory formation
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Sorted by citations
Thibault, B., Ramos-Delgado, F., & Guillermet-Guibert, J. (2023) · Cancers · doi:10.3390/cancers15030784 · Cited by 40
PI(3)P coordinates SNX17- and SNX27-dependent protein recycling for long-term synaptic plasticity
Rivero-Ríos, P., Uygun, T., Chavis, G. D., Lee, H., Duan, B., Sutton, M. A., & Weisman, L. S. (2025) · Journal of Cell Biology · doi:10.1083/jcb.202411198 · Cited by 1
Metadata
- Authors
- Wang, L., Budolfson, K., & Wang, F.
- Venue
- Neuroscience
- Publisher
- Elsevier BV
- Published
- 2011-01
- Volume
- 172
- Pages
- 427-442
- ISSN
- 0306-4522
- PMC
- PMC3010427
- Cited by
- 51
- References
- 5
- Language
- en
- Licence
- Funders
- National Institute of Dental and Craniofacial Research
- Wings for Life
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