Cited by 14Mindfulness and Compassion InterventionsMultiple Sclerosis Research StudiesCancer survivorship and care

Intervenciones psicoterapéuticas y psicosociales para el manejo del estrés en esclerosis múltiple: aportación de intervenciones basadas en mindfulness

Open access
Muñoz San José, A., Oreja-Guevara, C., Cebolla Lorenzo, S., Carrillo Notario, L., Rodríguez Vega, B., Bayón Pérez, C.·2016·Neurología

Abstract

Depression or anxiety in multiple sclerosis (MS) has been linked to a more severe course of the disease and higher numbers of relapses, in addition to poorer treatment adherence and exacerbated immune system dysregulation. Recent investigations indicate that psychotherapeutic interventions for stress management, such as mindfulness-based interventions (MBIs), could improve quality of life, depression, anxiety, and fatigue in MS patients. Mindfulness fosters the ability to slow down and observe experiences as they truly are, which improves affect regulation. Mindfulness is acquired through training; its advantage over other psychotherapeutic interventions is that effects may remain over time, since cultivating mindfulness depends on regular practising of abilities learned during training. The objective of this article is to review the current evidence of psychotherapeutic and psychosocial interventions, including MBIs for stress management, and their beneficial effects on MS patients.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.nrl.2015.07.014

Cites

26 of 26 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 69

  1. Weinstock-Guttman B, Jacobs LD, Brownscheidle CM, Baier M, Rea DF, Apatoff BR, et al. Multiple sclerosis characteristics in African American patients in the New York State Multiple Sclerosis Consortium. Mult Scler. 2003;9:293-8.
  2. Lublin FD, Reingold SC. Defining the clinical course of multiple sclerosis: Results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. Neurology. 1996;46:907-11.
  3. Lublin FD, Reingold SC, Cohen JA, Cutter GR, Sørensen PS, Thompson AJ, et al. Defining the clinical course of multiple sclerosis: The 2013 revisions. Neurology. 2014;83:278-86.
  4. Compston A, Confavreux C. The distribution of multiple scle- rosis. McAlpine's Multiple Sclerosis. 4 th ed. London: Churchill Livingstone Elsevier; 2005. p. 71-112.
  5. Browne P, Chandraratna D, Angood C, Tremlett H, Baker C, Taylor BV, et al. Atlas of Multiple Sclerosis 2013: A gro- wing global problem with widespread inequity. Neurology. 2014;83:1022-4.
  6. Brück W, Gold R, Lund BT, Oreja-Guevara C, Prat A, Spencer CM, et al. Therapeutic decisions in multiple sclerosis: Moving beyond efficacy. JAMA Neurol. 2013;70:1315-24.
  7. De Sa JC, Airas L, Bartholome E, Grigoriadis N, Mattle H, Oreja- Guevara C, et al. Symptomatic therapy in multiple sclerosis: A review for a multimodal approach in clinical practice. Ther Adv Neurol Disord. 2011;24:139-68.
  8. Feinstein A. Multiple sclerosis and depression. Mult Scler. 2011;17:1276-81.
  9. Feinstein A, O'Connor P, Gray T, Feinstein K. The effects of anxiety on psychiatric morbidity in patients with multiple scle- rosis. Mult Scler. 1999;5:323-6.
  10. Benito-Leon J, Morales MJ, Rivera-Navarro J, Mitchell A. A review about the impact of multiple sclerosis on health-related quality of life. Disabil Rehabil. 2003;25:1291-304.
  11. Janssens A, van Dorn P, de Boer J, van der Meché FG, Passchier J, Hintzen RQ. Impact of recently diagnosed multiple sclerosis on quality of life, anxiety, depression and distress of patients and partners. Acta Neurol Scand. 2003;108:389-95.
  12. Mohr DC, Dick PP, Russo D, Pinn J, Boudewyn AC, Likosky W, et al. The psychosocial impact of multiple scleoris: Exploring the patient's perspective. Heal Psychol. 1999;18:376-82.
  13. Morris G, Berk M, Walder KMM. Central pathways causing fati- gue in neuro-inflammatory and autoimmune illnesses. BMC Med. 2015;6:28.
  14. Morris G, Maes M. Myalgic encephalomyelitis/chronic fatigue syndrome and encephalomyelitis disseminata/multiple sclero- sis showremarkable levels of similarity in phenomenology and neuroimmune characteristics. BMC Med. 2013;17:205.
  15. Julian LJ, Vella LVT, Hadjimichael O, Mohr DC. Employment in multiple sclerosis. Exiting and re-entering the work force. J Neurol. 2008;255:1354-60.
  16. Khan F, Amatya B, Galea M. Management of fatigue in persons with multiple sclerosis. Front Neurol. 2014;15:177.
  17. Feuillet L, Reuter F, Audoin B, Malikova I, Barrau K, Cherif AA, et al. Early cognitive impairment in patients with clinically isolated syndrome suggestive of multiple sclerosis. Mult Scler. 2007;13:124-7.
  18. Filippi M, Rocca MA, Benedict RH, DeLuca J, Geurts JJ, Rombouts SA, et al. The contribution of MRI in assessing cog- nitive impairment in multiple sclerosis. Neurology. 2010;75: 2121-8.
  19. Henry A, Tourbah A, Chaunu MP, Rumbach L, Montreuil M, Bak- chine S. Social cognition impairments in relapsing remitting multiple sclerosis. J Int Neuropsychol Soc. 2011;17:1122-31.
  20. Kraemer M, Herold M, Uekermann J, Kis B, Wiltfang J, Daum I, et al. Theory of mind and empathy in patients at an early stage of relapsing remitting multiple sclerosis. Clin Neurol Neu- rosurg. 2013;115:1016-22.
  21. Banati M, Sandor J, Mike A, Illes E, Bors L, Feldmann A, et al. Social cognition and Theory of Mind in patients with relapsing- remitting multiple sclerosis. Eur J Neurol. 2010;17:426-33.
  22. Mohr DC, Goodkin DE, Likosky W, Gatto N, Baumann KA, Rudick RA. Treatment of depression improves adherence to inter- feron beta-1b therapy for multiple sclerosis. Arch Neurol. 1997;54:531-3.
  23. Mohr DC, Goodkin DE, Islar J, Hauser SL, Genain CP. Treatment of depression is associated with suppression of nonspecific and antigen-specific T(H)1 responses in multiple sclerosis. Arch Neurol. 2001;58:1081-6.
  24. Mohr DC, Hart SL, Julian L, Cox D, Pelletier D. Association between stressful life events and exacerbation in multiple sclerosis: A meta-analysis. BMJ Br Med J. 2004;328:731.
  25. Potagas C, Mitsonis C, Watier L, Dellatolas G, Retziou A, Mitro- poulos P, et al. Influence of anxiety and reported stressful life events on relapses in multiple sclerosis: A prospective study. Mult Scler. 2008;14:1262-8.
  26. Heesen C, Gold SM. Don't stress about it! Is stress management a disease-modifying therapy for multiple sclerosis? Neurology. 2012;79:398-9.
  27. Mohr DC, Lovera J, Brown T, Cohen B, Neylan T, Henry R, et al. A randomized trial of stress management for the prevention of new brain lesions in MS. Neurology. 2012;79:412-9.
  28. Mohr DC, Goodkin DE, Bacchetti P, Boudewyn AC, Huang L, Marrietta P, et al. Psychological stress and the subse- quent appearance of new brain MRI lesions in MS. Neurology. 2000;55:55-61.
  29. Golan D, Somer E, Dishon S, Cuzin-Disegni L, Miller A. Impact of exposure to war stress on exacerbations of multiple sclerosis. Ann Neurol. 2008;64:143-8.
  30. Yamout B, Itani S, Hourany R, Sibaii AM, Yaghi S. The effect of war stress on multiple sclerosis exacerbations and radiological disease activity. J Neurol Sci. 2010;288(1-2):42-4.
  31. Lupien SJ, McEwen BS, Gunnar MR, Heim C. Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci. 2009;10:434-45.
  32. Nicolaides NC, Kyratzi E, Lamprokostopoulou A, Chrousos GP, Charmandari E. Stress, the stress system and the role of glu- cocorticoids. Neuroimmunomodulation. 2015;22(1-2):6-19.
  33. Maes M. Elevated serum interleukin-6 (IL-6) and IL-6 recep- tor concentrations in posttraumatic stress disorder following accidental man-made traumatic events. Biol Psychiatry. 1999;45:833-9.
  34. Raison CL, Capuron L, Miller AH. Cytokines sing the blues: Inflammation and the pathogenesis of depression. Trends Immunol. 2006;27:24-31.
  35. Lotrich FE, El-Gabalawy H, Guenther LC, Ware CF. The role of inflammation in the pathophysiology of depression: Dif- ferent treatments and their effects. J Rheumatol Suppl. 2011;88:48-54.
  36. Bruce JM, Hancock LM, Arnett P, Lynch S. Treatment adhe- rence in multiple sclerosis: Association with emotional status, personality, and cognition. J Behav Med. 2010;33:219-27.
  37. Fischer A, Heesen C, Gold SM. Biological outcome measure- ments for behavioral interventions in multiple sclerosis. Ther Adv Neurol Disord. 2011;4:217-29.
  38. Plow MA, Finlayson M, Rezac M. A scoping review of self- management interventions for adults with multiple sclerosis. PM R. 2011;3:251-62.
  39. Lejbkowicz I, Caspi O, Miller A. Participatory medicine and patient empowerment towards personalized health- care in multiple sclerosis. Expert Rev Neurother. 2012;12: 343-52.
  40. Heesen C, Köpke S, Kasper J, Poettgen J, Tallner A, Mohr DC, et al. Behavioral interventions in multiple scle- rosis: A biopsychosocial perspective. Expert Rev Neurother. 2012;12:1089-100.
  41. Thomas PW, Thomas S, Hillier C, Galvin K, Baker R. Psycholo- gical interventions for multiple sclerosis. Cochrane Database Syst Rev. 2006;1:CD004431. Review.
  42. Motl RW, Goldman MD, Benedict RH. Walking impairment in patients with multiple sclerosis: Exercise training as a treat- ment option. Neuropsychiatr Dis Treat. 2010;16:767-74.
  43. Motl RW, Gosney JL. Effect of exercise training on qua- lity of life in multiple sclerosis: A meta-analysis. Mult Scler. 2008;14:129-35.
  44. Snook EM, Motl RW. Effect of exercise training on walking mobi- lity in multiple sclerosis: A meta-analysis. Neurorehabil Neural Repair. 2009;23:108-16.
  45. Andreasen AK, Stenager E, Dalgas U. The effect of exer- cise therapy on fatigue in multiple sclerosis. Mult Scler. 2011;17:1041-54.
  46. Asano M, Finlayson ML. Meta-analysis of three different types of fatigue management interventions for people with multiple sclerosis: Exercise, education, and medication. Mult Scler Int. 2014, 2014:798285.
  47. Bansi J, Bloch W, Gamper U, Riedel S, Kesselring J. Endurance training in MS: Short-term immune responses and their relation to cardiorespiratory fitness, health-related quality of life, and fatigue. J Neurol. 2013;260:2993-3001.
  48. Dalgas U, Stenager E. Exercise and disease progression in multiple sclerosis: Can exercise slow down the progres- sion of multiple sclerosis? Ther Adv Neurol Disord. 2012;5: 81-95.
  49. Köpke S, Kasper J, Mühlhauser I, Nübling M, Heesen C. Patient education program to enhance decision autonomy in multiple sclerosis relapse management: A randomized-controlled trial. Mult Scler. 2009;15:96-104.
  50. Solari A, Martinelli V, Trojano M, Lugaresi A, Granella F, Gior- dano A, et al. An information aid for newly diagnosed multiple sclerosis patients improves disease knowledge and satisfac- tionwith care. Mult Scler. 2010;16:1393-405.
  51. Prunty MC, Sharpe L, Butow P, Fulcher G. The motherhood choice: A decision aid for women with multiple sclerosis. Patient Educ Couns. 2008;71:108-15.
  52. Young FK, Brooks BR. Patient teaching manuals improve reten- tion of treatment information-a controlled clinical trial in multiplesclerosis. J Neurosci Nurs. 1986;18:26-8.
  53. Lambert MJ, Bergin AE. The effectiveness of psychotherapy. En: Bergin AE, Garfield SLE, editores. Handbook of psychothe- rapy and behavior change. 4 th ed. New York: Wiley; 1994. p. 143-89.
  54. Mohr DC, Hart SL, Goldberg A. Effects of treatment for depression on fatigue in multiple sclerosis. Psychosom Med. 2003;65:542-7.
  55. Van Kessel K, Moss-Morris R, Willoughby E, Chalder T, John- son MH, Robinson E. A randomized controlled trial of cognitive behavior therapy for multiple sclerosis fatigue. Psychosom Med. 2008;70:205-13.
  56. Reynard AK, Sullivan AB, Rae-Grant A. A systematic review of stress-management interventions for multiple sclerosis patients. Int J MS Care. 2014;16:140-4. Fall.
  57. Mohr DC, Epstein L, Luks TL, Goodkin D, Cox D, Goldberg A. Brain lesion volume and neuropsychological function predict efficacy of treatment for depression in multiple sclerosis. J Consult Clin Psychol. 2003;71:1017-24.
  58. Bishop SR, Lau M, Shapiro SL, Carlson L, Anderson ND, Carmody J, et al. Mindfulness: A proposed operational definition. Clin Psychol Sci Pract. 2004;11:230-41.
  59. Williams JM. Mindfulness and psychological process. Emotion. 2010;10:1-7.
  60. Germer C, Siegel R, Fulton P. Mindfulness and psychotherapy. New York: Guilford Press; 2005.
  61. Hayes SC, Wilson KG, Gifford EV, Follette VM, Strosahl K. Experimental avoidance and behavioral disorders: A functional dimensional approach to diagnosis and treatment. J Consult Clin Psychol. 1996;64:1152-68.
  62. Cebolla A, Miró Barrachina MT. The effects of mindfulness- based cognitive therapy. Psychol Spain. 2009;13:9-16.
  63. Segal ZV, Williams MG, Teasdale JD. Mindfulness based cog- nitive therapy for depression: A new approach to preventing relapse. New York: The Guilford Press; 2002.
  64. Teasdale JD, Segal ZV, Williams JM, Ridgeway VA, Soulsby JM, Lau MA. Prevention of relapse/recurrence in major depression by mindfulnessbased cognitive therapy. J Consult Clin Psychol. 2000;68:615-23.
  65. Linehan MM. Dialectical behavior therapy for borderline personality disorder. Theory and method. Bull Menn Clin. 1987;51:261-76.
  66. Lawrence M, Booth J, Mercer S, Crawford E. A systema- tic review of the benefits of mindfulness-based interventions following transient ischemic attack and stroke. Int J Stroke. 2013;8:465-74.
  67. Robinson FP, Mathews HL, Witek-Janusek L. Psycho-endocrine- immune response to mindfulness-based stress reduction in individuals infected with the human immunodeficiency virus: A quasiexperimental study. J Altern Complement Med. 2003;9:683-94.
  68. Davidson RJ, Kabat-Zinn J, Schumacher J, Rosenkranz M, Muller D, Santorelli SF, et al. Alterations in brain and immune function produced by mindfulness meditation. Psychosom Med. 2003;65:564-70.
  69. Carlson LE, Speca M, Patel KD, Goodey E. Mindfulness- based stress reduction in relation to quality of life, mood, symptoms of stress and levels of cortisol, dehydroepiandros- terone sulfate (DHEAS) and melatonin in breast and pros- tate cancer outpatients. Psychoneuroendocrinology. 2004;29: 448-74.

Cited by

Sorted by citations

Authors
Muñoz San José, A., Oreja-Guevara, C., Cebolla Lorenzo, S., Carrillo Notario, L., Rodríguez Vega, B., & Bayón Pérez, C.
Venue
Neurología
Publisher
Elsevier BV
Published
2016-03
Volume
31
Issue
2
Pages
113-120
ISSN
0213-4853 (ISSN-L)
OpenAlex
W1919708171
Cited by
14
References
26
Citations by year
2024: 1 · 2022: 1 · 2020: 2 · 2019: 3 · 2018: 4 · 2017: 3
FWCI
0.33
Type
journal article
Language
es
Open access
Locations
  • Neurología (publishedVersion)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
Keywords
multiple sclerosis, mindfulness-based interventions, stress management, psychotherapeutic interventions, psychosocial interventions, depression, anxiety, fatigue, quality of life, emotion regulation, relapse
MeSH terms
Psychosocial Support Systems, Anxiety, Depression, Humans, Multiple Sclerosis, Psychotherapy, Quality of Life, Stress, Psychological, Mindfulness

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review