The DOI matches its Crossref record; 284 of the 291 references it cites were found in a registry or an index.
Magnetic Resonance Imaging of Myelin
Open accessAbstract
The ability to measure myelin in vivo has great consequences for furthering our knowledge of normal development, as well as for understanding a wide range of neurological disorders. The following review summarizes the current state of myelin imaging using MR. We consider five MR techniques that have been used to study myelin: 1) conventional MR, 2) MR spectroscopy, 3) diffusion, 4) magnetization transfer, and 5) T2 relaxation. Fundamental studies involving peripheral nerve and MR/histology comparisons have aided in the interpretation and validation of MR data. We highlight a number of important findings related to myelin development, damage, and repair, and we conclude with a critical summary of the current techniques available and their potential to image myelin in vivo.
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“a relatively abundant MAG level might indicate a relatively intact myelin-axon interface in the CD1 mice, albeit a damaged outer myelin sheath.”
From Strain differences in cuprizone induced demyelination (2017) · cites this paper as [37]
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Metadata
- Authors
- Laule, C., Vavasour, I. M., Kolind, S. H., Li, D. K. B., Traboulsee, T. L., Moore, G. R. W., & MacKay, A. L.
- Affiliations
- University of British Columbia (CA)
- University of British Columbia Hospital (CA)
- Corresponding author
- Laule, Cornelia
- Venue
- Neurotherapeutics
- Publisher
- Elsevier BV
- Published
- 2007-07
- Volume
- 4
- Issue
- 3
- Pages
- 460-484
- ISSN
- 1878-7479 (ISSN-L)
- PMC
- PMC7479725
- OpenAlex
- W2080423736
- Cited by
- 334
- References
- 291
- Citations by year
- 2026: 9 · 2025: 17 · 2024: 20 · 2023: 19 · 2022: 17 · 2021: 28 · 2020: 32 · 2019: 28 · 2018: 23 · 2017: 27 · 2016: 16 · 2015: 17 · 2014: 18 · 2013: 15 · 2012: 8
- FWCI
- 1.15
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neurotherapeutics (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Multiple Sclerosis Society of Canada
- Multiple Sclerosis Society
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Health Sciences › Medicine › Clinical Neurology › Multiple Sclerosis Research Studies
- Keywords
- myelin imaging, myelin, myelination, myelin damage, remyelination, MR spectroscopy, diffusion MRI, magnetization transfer, T2 relaxation, peripheral nerves
- MeSH terms
- Animals, Humans, Magnetic Resonance Imaging, Myelin Sheath
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