Minor components of olive oil facilitate the triglyceride clearance from postprandial lipoproteins in a polarity-dependent manner in healthy men
Open accessAbstract
Postprandial triglyceride-rich lipoproteins (TRLs) are recognized as atherogenic particles whose lipid composition and function can be modified by the composition of dietary oils. This study was designed to test the hypothesis that minor components of pomace olive oil (POMACE) can not only change the composition of postprandial TRL but also affect the clearance of triglyceride (TG) molecular species of postprandial TRL. Meals enriched in either POMACE or refined olive oil (OLIVE) were administered to 10 healthy young men. TRL were isolated from serum at 2, 4, and 6 hours postprandially, and their fatty acid and TG molecular species compositions were analyzed by gas chromatography. The apolipoprotein B concentration was determined by immunoturbidimetry. POMACE and OLIVE, differing mainly in their unsaponifiable fraction, led to similar fatty acid and TG molecular species profiles in postprandial TRL. However, POMACE-TRL presented a higher particle size, estimated as TG to apolipoprotein B ratio, which was also found for the main TG molecular species (trioleoyl-glycerol, palmitoyl-dioleoyl-glycerol, palmitoyl-oeloyl-linoleoyl-glycerol, and dioleoyl-linoleoyl-glycerol). TG from POMACE-TRL also showed higher clearance rates. In this regard, apolar TG (with a higher equivalent carbon number) disappeared more rapidly from TRL particles obtained after the ingestion of either POMACE or OLIVE. In conclusion, minor components of POMACE facilitated TG clearance from TRL by modifying their particle size and the hydrolysis of the most apolar species.
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The effect of consuming OPO has only been addressed in postprandial studies, which showed that OPO intake resulted in triglyceride-rich lipoproteins with higher particle size than after ROO and facilitated TG clearance from TRL.
“But the effect of consuming OPO has only been addressed in postprandial studies, showing that OPO intake resulted in triglyceride-rich lipoproteins (TRL) with higher particle size than after the intake of ROO and facilitated TG clearance from TRL [23, 24].”
From Olive pomace oil can improve blood lipid profile: a randomized, blind, crossover, controlled clinical trial in healthy and at-risk volunteers (2022) · cites this paper as [24]
Lower Apo B concentration in postprandial TRL after ingestion of OPO by healthy subjects compared to ROO has been reported.
“This is in line with the lower Apo B concentration in postprandial TRL after ingestion of OPO by healthy subjects compared to ROO [24].”
From Olive pomace oil can improve blood lipid profile: a randomized, blind, crossover, controlled clinical trial in healthy and at-risk volunteers (2022) · cites this paper as [24]
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Nutritional and other health properties of olive pomace oil
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“Depending on the processing of the olives, different categories of olive oil are obtained: extra virgin (EVOO), virgin (VOO), refined (ROO) olive oils, and olive pomace oil (OPO), all having a high content of monounsaturated fatty acids (MUFA), mainly oleic acid.”
BackgroundResultInfluential
- Authors
- Cabello-Moruno, R., Martinez-Force, E., Montero, E., & Perona, J. S.
- Affiliations
- Consejo Superior de Investigaciones Científicas (ES)
- Hospital Universitario Virgen del Rocío (ES)
- Venue
- Nutrition Research
- Publisher
- Elsevier BV
- Published
- 2014-01
- Volume
- 34
- Issue
- 1
- Pages
- 40-47
- ISSN
- 0271-5317 (ISSN-L)
- OpenAlex
- W1994894696
- Cited by
- 13
- References
- 25
- Citations by year
- 2024: 1 · 2023: 1 · 2022: 3 · 2021: 1 · 2020: 1 · 2019: 2 · 2016: 1 · 2015: 1 · 2014: 2
- FWCI
- 0.61
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Nutrition Research (publishedVersion)
- PubMed (publishedVersion)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, other-oa)
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Keywords
- olive pomace oil, refined olive oil, triglyceride-rich lipoproteins, postprandial lipoproteins, triglyceride clearance, unsaponifiable matter, apolipoprotein B, particle size, fatty acid composition, edible oils, lipolysis
- MeSH terms
- Olive Oil, Adult, Apolipoproteins B, Fatty Acids, Humans, Lipoproteins, Male, Metabolic Clearance Rate, Particle Size, Plant Oils, Triglycerides, Body Mass Index, Postprandial Period, Meals
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