Modifications in Postprandial Triglyceride-Rich Lipoprotein Composition and Size after the Intake of Pomace Olive Oil
Abstract
OBJECTIVE: This study was designed to determine the composition of postprandial triglyceride-rich lipoproteins (TRL) after the intake of pomace olive oil (POO), which is a subproduct of the extraction of virgin olive oil (VOO) and presents a high concentration of minor components with biological activity. METHODS: Meals enriched in POO and refined olive oil (ROO) were administrated to 9 healthy young men and blood was extracted every hour during a postprandial period of 7 hours. Serum and TRL lipid composition were measured by enzymatic and chromatographic methods and apolipoprotein B composition by SDS-PAGE. RESULTS: POO and ROO showed a very similar fatty acid composition but differed in their unsaponifiable fraction. The content of phytosterols, tocopherols, terpenic acids and alcohols and fatty alcohols was much higher in POO than in ROO. Serum lipids were not affected by the administration of the oils but the triglyceride concentration in TRL and the size of the particles (p < 0.05) after POO was higher at time point 2 h and lower at time point 4 h compared with ROO. In contrast, the number of TRL particles was lower after POO, although the rate of clearance was similar. CONCLUSION: We suggest that the unsaponifiable fraction between the two olive oils affect the size and composition of postprandial TRL, which might have a relevant impact on their atherogenicity.
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The effect of consuming OPO has only been addressed in postprandial studies, which showed that OPO intake resulted in triglyceride-rich lipoproteins with higher particle size than after ROO and facilitated TG clearance from TRL.
“But the effect of consuming OPO has only been addressed in postprandial studies, showing that OPO intake resulted in triglyceride-rich lipoproteins (TRL) with higher particle size than after the intake of ROO and facilitated TG clearance from TRL [23, 24].”
From Olive pomace oil can improve blood lipid profile: a randomized, blind, crossover, controlled clinical trial in healthy and at-risk volunteers (2022) · cites this paper as [23]
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Nutritional and other health properties of olive pomace oil
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“This is in line with the lower Apo B concentration in postprandial TRL after ingestion of OPO by healthy subjects compared to ROO [24].”
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- Authors
- Cabello-Moruno, R., Perona, J. S., Osada, J., Garcia, M., & Ruiz-Gutierrez, V.
- Affiliations
- Consejo Superior de Investigaciones Científicas (ES)
- Hospital Universitario Virgen del Rocío (ES)
- ORCID
- Perona, Javier S.
- Venue
- Journal of the American College of Nutrition
- Publisher
- Informa UK Limited
- Published
- 2007-02
- Volume
- 26
- Issue
- 1
- Pages
- 24-31
- ISSN
- 0731-5724 (ISSN-L)
- 1541-1087
- OpenAlex
- W2033181019
- Cited by
- 22
- References
- 41
- Citations by year
- 2023: 1 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 2 · 2015: 3 · 2014: 2 · 2013: 4 · 2012: 1
- FWCI
- 1.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American College of Nutrition (publishedVersion)
- PubMed (publishedVersion)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion)
- Funders
- Japan Society for the Promotion of Science
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
- Keywords
- olive pomace oil, triglyceride-rich lipoproteins, postprandial lipemia, lipoprotein particle size, unsaponifiable matter, phytosterols, tocopherols, fatty alcohols, apolipoprotein B, refined olive oil, atherogenicity, serum lipids
- MeSH terms
- Olive Oil, Adult, Apolipoproteins B, Biological Availability, Electrophoresis, Polyacrylamide Gel, Humans, Lipoproteins, Male, Particle Size, Plant Oils, Triglycerides, Cross-Over Studies, Postprandial Period, Area Under Curve
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