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International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas

Tanaka, Masao, Fernández-del Castillo, Carlos, Adsay, Volkan, Chari, Suresh, Falconi, Massimo, Jang, Jin-Young, Kimura, Wataru, Levy, Philippe, Pitman, Martha Bishop, Schmidt, C. Max, Shimizu, Michio, Wolfgang, Christopher L., Yamaguchi, Koji, Yamao, Kenji·2012·Pancreatology

DOI 10.1016/j.pan.2012.04.004

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Abstract

The international consensus guidelines for management of intraductal papillary mucinous neoplasm and mucinous cystic neoplasm of the pancreas established in 2006 have increased awareness and improved the management of these entities. During the subsequent 5 years, a considerable amount of information has been added to the literature. Based on a consensus symposium held during the 14th meeting of the International Association of Pancreatology in Fukuoka, Japan, in 2010, the working group has generated new guidelines. Since the levels of evidence for all items addressed in these guidelines are low, being 4 or 5, we still have to designate them "consensus", rather than "evidence-based", guidelines. To simplify the entire guidelines, we have adopted a statement format that differs from the 2006 guidelines, although the headings are similar to the previous guidelines, i.e., classification, investigation, indications for and methods of resection and other treatments, histological aspects, and methods of follow-up. The present guidelines include recent information and recommendations based on our current understanding, and highlight issues that remain controversial and areas where further research is required.

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High‐grade atypical epithelial cells in pancreatic mucinous cysts are a more accurate predictor of malignancy than “positive” cytology
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Patient outcomes after total pancreatectomy: a single centre contemporary experience
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Authors: Tanaka, M., Fernández-del Castillo, C., Adsay, V., Chari, S., Falconi, M., Jang, J.-Y., Kimura, W., Levy, P., Pitman, M. B., Schmidt, C. M., Shimizu, M., Wolfgang, C. L., Yamaguchi, K., & Yamao, K.
Affiliations: Kyushu University (JP)
Emory University Hospital (US)
Mayo Clinic (US)
University of Verona (IT)
Seoul National University (KR)
Yamagata University (JP)
Harvard University (US)
Indiana University Indianapolis (US)
Saitama International Medical Center (JP)
Johns Hopkins University (US)
University of Occupational and Environmental Health Japan (JP)
Aichi Cancer Center Hospital (JP)
Corresponding author: Tanaka, Masao
ORCID: Tanaka, Masao
Adsay, Volkan
Chari, Suresh
Falconi, Massimo
Jang, Jin-Young
Kimura, Wataru
Schmidt, C. Max
Wolfgang, Christopher L.
Yamaguchi, Koji
Yamao, Kenji
Venue: Pancreatology
Publisher: Elsevier BV
Published: 2012-05
Volume: 12
Issue: 3
Pages: 183-197
ISSN: 1424-3903 (ISSN-L)
DOI: 10.1016/j.pan.2012.04.004
OpenAlex: W2148560417
Cited by: 2,354
References: 209
Citations by year: 2026: 65 · 2025: 70 · 2024: 80 · 2023: 113 · 2022: 118 · 2021: 136 · 2020: 161 · 2019: 182 · 2018: 239 · 2017: 272 · 2016: 256 · 2015: 270 · 2014: 204 · 2013: 154 · 2012: 29
FWCI: 104.22
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Pancreatology (publishedVersion)
PubMed (publishedVersion)
Archivio Istituzionale della Ricerca - Università Vita-Salute San Raffaele (submittedVersion)
Università Politecnica delle Marche (Università Politecnica delle Marche) (submittedVersion)
Topics: Health Sciences › Medicine › Oncology › Pancreatic and Hepatic Oncology Research
Health Sciences › Medicine › Oncology › Neuroendocrine Tumor Research Advances
Health Sciences › Medicine › Surgery › Pancreatitis Pathology and Treatment
Keywords: intraductal papillary mucinous neoplasm, mucinous cystic neoplasm, pancreatic cysts, classification, diagnostic workup, surgical resection, histopathology, follow-up
MeSH terms: Humans, Pancreas, Pancreatic Neoplasms, Neoplasms, Cystic, Mucinous, and Serous, Papilloma, Intraductal, Carcinoma, Pancreatic Ductal

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International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas

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