Acute effects of UVR on human eyes and skin
Open accessAbstract
Solar UVR ( approximately 295-400 nm) has acute clinical effects on the eyes and the skin. The only effect on the eye is inflammation of the cornea (photokeratitis), which is caused by UVB (and non-solar UVC) and resolves without long-term consequences within 48 h. The effects on the skin are more extensive and include sunburn (inflammation), tanning and immunosuppression for which UVB is mainly responsible. Tanning is modestly photoprotective against further acute UVR damage. Skin colour is also transiently changed by UVA-dependent immediate pigment darkening, the function of which is unknown. Skin type determines sensitivity to the acute and chronic effects of UVR on the skin. Some of the photochemical events that initiate acute effects are also related to skin cancer. Solar UVB is also responsible for the synthesis of vitamin D.
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Skin photoaging manifests as dry skin, coarse wrinkles, irregular pigmentation, and loss of skin elasticity.
“its manifestations include dry skin, coarse wrinkle, irregular pigmentation, and loss of skin elasticity”
From Boosting the Photoaged Skin: The Potential Role of Dietary Components (2021) · cites this paper as [4]
More than 80% of facial skin aging is caused by exposure to UV.
“Studies have shown that more than 80% of facial skin aging is caused by exposure to UV [4].”
From Boosting the Photoaged Skin: The Potential Role of Dietary Components (2021) · cites this paper as [4]
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- Authors
- Young, A. R.
- Affiliations
- St Thomas' Hospital (GB)
- Corresponding author
- Young, Antony R.
- ORCID
- Young, Antony R.
- Venue
- Progress in Biophysics and Molecular Biology
- Publisher
- Elsevier BV
- Published
- 2006-09
- Volume
- 92
- Issue
- 1
- Pages
- 80-85
- ISSN
- 0079-6107 (ISSN-L)
- OpenAlex
- W2076008843
- Cited by
- 267
- References
- 50
- Citations by year
- 2026: 11 · 2025: 11 · 2024: 22 · 2023: 13 · 2022: 16 · 2021: 22 · 2020: 16 · 2019: 21 · 2018: 15 · 2017: 7 · 2016: 13 · 2015: 18 · 2014: 12 · 2013: 10 · 2012: 8
- FWCI
- 1.42
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Progress in Biophysics and Molecular Biology (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Health Sciences › Medicine › Ophthalmology › Ocular and Laser Science Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
- Keywords
- ultraviolet radiation, photokeratitis, keratitis, UV-B radiation, UVA, sunburn, tanning, immunosuppression, skin pigmentation, skin type, skin cancer, vitamin D synthesis, photoprotection
- MeSH terms
- Acute Disease, Animals, Eye, Eye Injuries, Humans, Keratitis, Neoplasms, Radiation-Induced, Radiation Injuries, Radiodermatitis, Skin, Skin Neoplasms, Sunlight, Ultraviolet Rays
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