Prevalence and prevention of cardiovascular disease and diabetes mellitus
Abstract
Noncommunicable diseases (NCDs) have become important causes of mortality on a global scale. According to the report of World Health Organization (WHO), NCDs killed 38 million people (out of 56 million deaths that occurred worldwide) during 2012. Cardiovascular diseases accounted for most NCD deaths (17.5 million NCD deaths), followed by cancers (8.2 million NCD deaths), respiratory diseases (4.0 million NCD deaths) and diabetes mellitus (1.5 million NCD deaths). Globally, the leading cause of death is cardiovascular diseases; their prevalence is incessantly progressing in both developed and developing nations. Diabetic patients with insulin resistance are even at a greater risk of cardiovascular disease. Obesity, high cholesterol, hypertriglyceridemia and elevated blood pressure are mainly considered as major risk factors for diabetic patients afflicted with cardiovascular disease. The present review sheds light on the global incidence of cardiovascular disease and diabetes mellitus. Additionally, measures to be taken to reduce the global encumbrance of cardiovascular disease and diabetes mellitus are highlighted.
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The increasing incidence of metabolic-related disease, such as diabetes and obesity, in developed countries and in developing nations adopting a Western diet and lifestyle supports the common body of evolutionary evidence.
“This common body of evolutionary evidence is supported by the increasing incidence of metabolic-related disease, such as diabetes and obesity, in developed countries and in developing nations adopting a Western diet and lifestyle [11,77].”
From Polycystic Ovary Syndrome: An Evolutionary Adaptation to Lifestyle and the Environment (2022) · cites this paper as [77]
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“This common body of evolutionary evidence is supported by the increasing incidence of metabolic-related disease, such as diabetes and obesity, in developed countries and in developing nations adopting a Western diet and lifestyle [11,77].”
BackgroundVarma, N., Cygankiewicz, I., Turakhia, M. P., Heidbuchel, H., Hu, Y.-F., Chen, L. Y., Couderc, J.-P., Cronin, E. M., Estep, J. D., Grieten, L., et al. (2021) · Circulation: Arrhythmia and Electrophysiology · doi:10.1161/circep.120.009204 · Cited by 74 · see citing works
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Ruan, Z., Yang, L., Shi, H., Yue, X., Wang, Y., Liang, M., & Hu, H. (2021) · Expert Review of Pharmacoeconomics & Outcomes Research · doi:10.1080/14737167.2021.1860022 · Cited by 15 · see citing works
- Authors
- Balakumar, P., Maung-U, K., & Jagadeesh, G.
- Affiliations
- AIMST University (MY)
- United States Food and Drug Administration (US)
- Corresponding author
- Jagadeesh, Gowraganahalli
- Venue
- Pharmacological Research
- Publisher
- Elsevier BV
- Published
- 2016-11
- Volume
- 113
- Issue
- Pt A
- Pages
- 600-609
- ISSN
- 1043-6618 (ISSN-L)
- OpenAlex
- W2528470914
- Cited by
- 663
- References
- 5
- Citations by year
- 2026: 35 · 2025: 75 · 2024: 95 · 2023: 126 · 2022: 70 · 2021: 106 · 2020: 72 · 2019: 43 · 2018: 19 · 2017: 20 · 2016: 2
- FWCI
- 4.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pharmacological Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
- Keywords
- cardiovascular disease, diabetes mellitus, non-communicable diseases, prevalence, disease prevention, insulin resistance, obesity, hypertriglyceridemia, hypercholesterolemia, hypertension, risk factors, global incidence
- MeSH terms
- Cardiovascular Diseases, Diabetes Mellitus, Humans, Insulin Resistance, Risk Factors, Prevalence
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