Epidemiology of Heart Failure
Open accessAbstract
Heart failure (HF) has been singled out as an epidemic and is a staggering clinical and public health problem, associated with significant mortality, morbidity, and healthcare expenditures, particularly among those aged ≥65 years. The case mix of HF is changing over time with a growing proportion of cases presenting with preserved ejection fraction for which there is no specific treatment. Despite progress in reducing HF-related mortality, hospitalizations for HF remain frequent and rates of readmissions continue to rise. To prevent hospitalizations, a comprehensive characterization of predictors of readmission in patients with HF is imperative and must integrate the impact of multimorbidity related to coexisting conditions. New models of patient-centered care that draw on community-based resources to support HF patients with complex coexisting conditions are needed to decrease hospitalizations.
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MI and ischemic cardiomyopathy are among the leading causes of heart failure, associated morbidity, and death worldwide and continue to impose staggering financial burden on healthcare systems.
“Despite advancements in clinical management, MI and ischemic cardiomyopathy are among the leading causes of heart failure, associated morbidity, and death worldwide 3,4 and continue to impose staggering financial burden on healthcare systems 3,5-8 .”
From Targeting the Immune-Fibrosis Axis in Myocardial Infarction and Heart Failure (2022) · cites this paper as [3]
The Etiology of Heart Failure—An Evolving Picture section reports that coronary disease causes a substantial share of heart-failure cases and discusses heart failure after MI. The Conclusion describes substantial mortality, morbidity, and healthcare expenditures from heart failure. These passages do not establish that MI and ischemic cardiomyopathy are leading causes of death worldwide or attribute the financial burden specifically to those conditions. (LLM, conf=0.85)
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- Authors
- Roger, V. L.
- Affiliations
- From the Department of Health Sciences Research and Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN.
- Venue
- Circulation Research
- Published
- 2013-08-30
- Volume
- 113
- Issue
- 6
- Pages
- 646-659
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- PMC
- PMC3806290
- OpenAlex
- W2168048360
- Cited by
- 1,728
- References
- 160
- Citations by year
- 2026: 43 · 2025: 63 · 2024: 101 · 2023: 126 · 2022: 142 · 2021: 179 · 2020: 170 · 2019: 198 · 2018: 183 · 2017: 217 · 2016: 128 · 2015: 78 · 2014: 59 · 2013: 27 · 2012: 11
- FWCI
- 66.22
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation Research (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Heart, Lung, and Blood Institute (R01HL59205, R01HL059205, R01HL072435, R01 HL-72435)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Keywords
- heart failure, heart failure epidemiology, heart failure hospitalization, heart failure readmission, predictors of readmission, multimorbidity, heart failure with preserved ejection fraction, heart failure mortality, health care expenditure, community-based care, patient-centered care
- MeSH terms
- Female, Heart Failure, Hospitalization, Humans, Male, Risk Factors, Incidence, Prevalence
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