Norsesquiterpene Hydrocarbon, Chemical Composition and Antimicrobial Activity of Rhaponticum carthamoides Root Essential Oil
Abstract
A detailed analysis of Rhaponticum carthamoides (Willd.) Iljin root essential oil was carried out by GC, GC-MS and GC-FTIR techniques. In total, 30 components were identified, accounting for 98.0% of total volatiles. A norsesquiterpene 13-norcypera-1(5),11(12)-diene (22.6%), followed by aplotaxene (21.2%) and cyperene (17.9%), were isolated and their structures confirmed by 1D and 2D-NMR spectra (COSY, ROESY, HSQC, HMBC and INADEQUATE). Selinene type sesquiterpenes and aliphatic hydrocarbons were among minor constituents of the essential oil. The oil exhibited antimicrobial activity against 5 of 9 strains of bacteria and yeast, when tested using broth micro-dilution method. Minimum inhibitory concentrations ranged between 32 and 256 microg/ml.
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Rhaponticum carthamoides roots are a source of essential oil with antimicrobial, antioxidant, and anti-inflammatory effects.
“Moreover, R. carthamoides roots are a source of essential oil, which is characterized by antimicrobial, antioxidant, and anti-inflammatory effects [13,107,114,115,116,117].”
From Ecdysterone and Turkesterone—Compounds with Prominent Potential in Sport and Healthy Nutrition (2024) · cites this paper as [116]
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- Authors
- Havlik, J., Budesinsky, M., Kloucek, P., Kokoska, L., Valterova, I., Vasickova, S., & Zeleny, V.
- Venue
- Phytochemistry
- Publisher
- Elsevier BV
- Published
- 2009-02
- Volume
- 70
- Issue
- 3
- Pages
- 414-418
- ISSN
- 0031-9422 (ISSN-L)
- OpenAlex
- W2076530241
- Cited by
- 37
- References
- 29
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 2 · 2022: 6 · 2021: 4 · 2020: 4 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 2 · 2014: 4 · 2013: 2
- FWCI
- 2.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Phytochemistry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministerstvo Školství, Mládeže a Tělovýchovy (MSM 60460701)
- Akademie Věd České Republiky (Z40550506)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant chemical constituents analysis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Sesquiterpenes and Asteraceae Studies
- Keywords
- Rhaponticum carthamoides, root essential oil, norsesquiterpenes, cyperene, sesquiterpenes, aliphatic hydrocarbons, chemical composition, antimicrobial activity, minimum inhibitory concentration
- MeSH terms
- Anti-Infective Agents, Bacteria, Chromatography, Gas, Gas Chromatography-Mass Spectrometry, Microbial Sensitivity Tests, Magnetic Resonance Spectroscopy, Oils, Volatile, Plant Oils, Yeasts, Molecular Structure, Spectroscopy, Fourier Transform Infrared, Plant Roots, Leuzea
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