Cited by 146Cellular transport and secretionLipid metabolism and biosynthesisProtein Kinase Regulation and GTPase Signaling

The DOI matches its Crossref record; 110 of the 110 references it cites were found in a registry or an index.

Acyl-coenzyme A binding domain containing 3 (ACBD3; PAP7; GCP60): An emerging signaling molecule

Open access

Fan, Jinjiang, Liu, Jun, Culty, Martine, Papadopoulos, Vassilios·2010·Progress in Lipid Research

DOI 10.1016/j.plipres.2009.12.003PMC PMC2873055

Open this paper in CoChat — free account

Abstract

Golgi body-mediated signaling has been linked to its fragmentation and regeneration during the mitotic cycle of the cell. During this process, Golgi-resident proteins are released to the cytosol and interact with other signaling molecules to regulate various cellular processes. Acyl-coenzyme A binding domain containing 3 protein (ACBD3) is a Golgi protein involved in several signaling events. ACBD3 protein was previously known as peripheral-type benzodiazepine receptor and cAMP-dependent protein kinase associated protein 7 (PAP7), Golgi complex-associated protein of 60kDa (GCP60), Golgi complex-associated protein 1 (GOCAP1), and Golgi phosphoprotein 1 (GOLPH1). In this review, we present the gene ontology of ACBD3, its relations to other Acyl-coenzyme A binding domain containing (ACBD) proteins, and its biological function in steroidogenesis, apoptosis, neurogenesis, and embryogenesis. We also discuss the role of ACBD3 in asymmetric cell division and cancer. New findings about ACBD3 may help understand this newly characterized signaling molecule and stimulate further research into its role in molecular endocrinology, neurology, and stem cell biology.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.plipres.2009.12.003

Cites

110 of 110 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Stem cells, cancer, and cancer stem cells
Reya, T., Morrison, S. J., Clarke, M. F., & Weissman, I. L. (2001) · Nature · doi:10.1038/35102167 · Cited by 9,738
Asymmetric and symmetric stem-cell divisions in development and cancer
Morrison, S. J., & Kimble, J. E. (2006) · Nature · doi:10.1038/nature04956 · Cited by 1,457
Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function
Papadopoulos, V., Baraldi, M., Guilarte, T. R., Knudsen, T. B., Lacapère, J.-J., Lindemann, P., Norenberg, M. D., Nutt, D., Weizman, A., Zhang, M.-R., et al. (2006) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2006.06.005 · Cited by 1,389
Self-citation
Role of long-chain fatty acyl-CoA esters in the regulation of metabolism and in cell signalling
Færgeman, N. J., & Knudsen, J. (1997) · Biochemical Journal · doi:10.1042/bj3230001 · Cited by 681
Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors.
Guidotti, A., Forchetti, C., Corda, M. G., Konkel, D. A., Bennett, C. D., & Costa, E. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.11.3531 · Cited by 646
Fatty acid oxidation is a dominant bioenergetic pathway in prostate cancer
Liu, Y. (2006) · Prostate Cancer and Prostatic Diseases · doi:10.1038/sj.pcan.4500879 · Cited by 433
Peripheral-Type Benzodiazepine/Diazepam Binding Inhibitor Receptor: Biological Role in Steroidogenic Cell Function*
PAPADOPOULOS, V. (1993) · Endocrine Reviews · doi:10.1210/edrv-14-2-222 · Cited by 417
Self-citation
Caspase-2 Is Localized at the Golgi Complex and Cleaves Golgin-160 during Apoptosis
Mancini, M., Machamer, C. E., Roy, S., Nicholson, D. W., Thornberry, N. A., Casciola-Rosen, L. A., & Rosen, A. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.149.3.603 · Cited by 379
gp25L/emp24/p24 Protein Family Members of the cis- Golgi Network Bind Both COP I and II Coatomer
Dominguez, M., Dejgaard, K., Füllekrug, J., Dahan, S., Fazel, A., Paccaud, J., Thomas, D. Y., Bergeron, J. J. M., & Nilsson, T. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.140.4.751 · Cited by 335
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
Petersen, P. H., Zou, K., Hwang, J. K., Jan, Y. N., & Zhong, W. (2002) · Nature · doi:10.1038/nature01124 · Cited by 330

Flagged first, then by citations

Show all 110 references

Research works printed but not linked: 4

[32]Jolly CA Wilton DC Schroeder F Microsomal fatty acyl-CoA transacylation and hydrolysis: fatty acyl-CoA species dependent modulation by liver fatty acyl-CoA binding proteins BBA-Mol Cell Biol L 2000 1483 185 197 10601707
[43]Scanlan MJ Gordan JD Williamson B Stockert E Bander NH Jongeneel V Gure AO Jaeger D Jaeger E Knuth A Antigens recognized by autologous antibody in patients with renal-cell carcinoma Int J Cancer 1999 83 456 464 10508479
[48]Groszer M Erickson R Scripture-Adams DD Dougherty JD Le BJ Zack JA Geschwind DH Liu X Kornblum HI Wu H PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry Proc Natl Acad Sci U S A 2006 103 111 116 16373498 PMC1325011
[96]Fang M Jaffrey SR Sawa A Ye K Luo X Snyder SH Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON Neuron 2000 28 183 193 11086993

Sorted by citations

Items 101–146 of 146

MULTI-RESOLUTION-TEST FOR CONSISTENT PHENOTYPE DISCRIMINATION AND BIOMARKER DISCOVERY IN TRANSLATIONAL BIOINFORMATICS
Han, H., Li, X., Ng, S.-K., & Zhou, J. (2013) · Journal of Bioinformatics and Computational Biology · doi:10.1142/s0219720013430105 · Cited by 6
ACBD3 Bioinformatic Analysis and Protein Expression in Breast Cancer Cells
Houghton-Gisby, J., Kerslake, R., Karteris, E., Mokbel, K., & Harvey, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23168881 · Cited by 6
Genome-wide identification and characterization of ACBP gene family in Populus reveal salinity alkali-responsive profiles
Chang, Y., Xu, X., Zheng, H., Xie, H., Li, B., Chen, S., Li, Y., & Dai, S. (2022) · Journal of Forestry Research · doi:10.1007/s11676-022-01485-2 · Cited by 5
New route for the activation of poly(ADP-ribose) polymerase-1: a passage that links poly(ADP-ribose) polymerase-1 to lipotoxicity?
Bai, P., & Csóka, B. (2015) · Biochemical Journal · doi:10.1042/bj20150598 · Cited by 5
Identification and characterization of interacting proteins of transcription factor DpWRI1-like related to lipid biosynthesis from microalga Dunaliella parva
Ruan, L., Huang, L., Wu, L., Gu, J., Liang, Y., Liang, X., & Shang, C. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e41165 · Cited by 4
ACBD3 is up-regulated in gastric cancer and promotes cell cycle G1-to-S transition in an AKT-dependent manner
Zheng, Y., Pei, Y., Tang, R., Zhou, X., Feng, Z., Li, D., Chen, H., Zeng, Z. R., Jiang, L., Cai, J., et al. (2021) · Experimental Cell Research · doi:10.1016/j.yexcr.2021.112752 · Cited by 4
Two typical acyl-CoA-binding proteins (ACBPs) are required for the asexual development and virulence of Phytophthora sojae
Pei, Y., Si, J., Navet, N., Ji, P., Zhang, X., Qiao, H., Xu, R., Zhai, Y., Miao, J., Tyler, B. M., et al. (2022) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2022.103695 · Cited by 4
The Chlamydia pneumoniae inclusion membrane protein Cpn0308 interacts with host protein ACBD3
Ma, L., Jia, X., Gao, Z., Zhou, Y., Cheng, Y., Li, P., & Jia, T. (2024) · Journal of Bacteriology · doi:10.1128/jb.00275-24 · Cited by 3
The acyl-CoA-binding protein VdAcb1 is essential for carbon starvation response and contributes to virulence in Verticillium dahliae
Zhuang, J., Zhang, Y., Sun, W., Zong, J., Li, J., Dai, X., Klosterman, S. J., Chen, J., Tian, L., Subbarao, K. V., et al. (2024) · aBIOTECH · doi:10.1007/s42994-024-00175-3 · Cited by 3
The 18 kDa Translocator Protein (TSPO): Cholesterol Trafficking and the Biology of a Prognostic and Therapeutic Mitochondrial Target
Frison, M., Mallach, A., Kennedy, E., & Campanella, M. (2017) · Biological and medical physics, biomedical engineering · doi:10.1007/978-3-319-55539-3_11 · Cited by 4
A Crucial Role of ACBD3 Required for Coxsackievirus Infection in Animal Model Developed by AAV-Mediated CRISPR Genome Editing Technique
Shin, H. J., Ku, K. B., Kim, S., Kim, H. S., Kim, Y.-S., Kim, Y.-S., Kim, S., & Kim, C. (2021) · Viruses · doi:10.3390/v13020237 · Cited by 3
A Conserved Cysteine Residue in Coxsackievirus B3 Protein 3A with Implication for Elevated Virulence
Voß, M., Pinkert, S., Kespohl, M., Gimber, N., Klingel, K., Schmoranzer, J., Laue, M. M., Gaida, M. M., Kloetzel, P., & Beling, A. (2022) · Viruses · doi:10.3390/v14040769 · Cited by 2
Cell Biology and Regulation of Adult and Aging Leydig Cell Steroidogenesis
Papadopoulos, V., Garza, S., & Zirkin, B. R. (2025) · Springer eBooks · doi:10.1007/978-3-031-96376-6_4 · Cited by 2
Self-citation
Congenital Lipoid Adrenal Hyperplasia
Miller, W. L. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1112-7_4 · Cited by 3
Dipeptide Ligands of TSPO
Деева, О. А., Яркова, М. А., Мокров, Г. В., Гудашева, Т. А., & Середенин, С. Б. (2022) · Pharmaceutical Chemistry Journal · doi:10.1007/s11094-022-02772-2 · Cited by 2
Mitochondria form contact sites with the nucleus to couple pro-survival retrograde responsePreprint
Desai, R., East, D. A., Hardy, L., Crosby, J., Rigon, M., Faccenda, D., Alvarez, M. S., Singh, A., Mainenti, M., Hussey, L. K., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/445411 · Cited by 2
Genome-Wide Characterization, Expression, and Functional Analysis of Acyl-CoA-Binding Protein (ACBP) Gene Family in Puccinellia tenuiflora
Zheng, H., Li, Y., Wang, S., Ni, X., Xu, X., & Dai, S. (2025) · Plants · doi:10.3390/plants14233551 · Cited by 1
Protoporphyrin IX regulates peripheral benzodiazepine receptor associated protein 7 (PAP7) and divalent metal transporter 1 (DMT1) in K562 cells
Okazaki, Y., & Glass, J. (2017) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2017.02.007 · Cited by 1
Translocator protein 18 ligand Emapunil protects against neurodegeneration in the MPTP mouse model of Parkinsonism
Gong, J. (2020) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-8039
Los autores no somos los sioux del teatro
Miralles, A. (2002) · Las puertas del drama: revista de la Asociación de Autores de Teatro
Peer Review #3 of "A reproducible approach to high-throughput biological data acquisition and integration (v0.1)"
(2015) · PeerJ · doi:10.7287/peerj.791v0.1/reviews/3
Peer Review #3 of "A reproducible approach to high-throughput biological data acquisition and integration (v0.2)"
(2015) · PeerJ · doi:10.7287/peerj.791v0.2/reviews/3
Peer Review #1 of "A reproducible approach to high-throughput biological data acquisition and integration (v0.1)"
(2015) · PeerJ · doi:10.7287/peerj.791v0.1/reviews/1
Peer Review #2 of "A reproducible approach to high-throughput biological data acquisition and integration (v0.1)"
(2015) · PeerJ · doi:10.7287/peerj.791v0.1/reviews/2
Peer Review #1 of "A reproducible approach to high-throughput biological data acquisition and integration (v0.2)"
(2015) · PeerJ · doi:10.7287/peerj.791v0.2/reviews/1
Lysosomal evasion of legionella pneumophilia the effector.
Vaughn, B. (2022) · doi:10.18297/etd/3833
Multifaceted involvement of ACBD6 in the metabolic reprogramming of breast cancerPreprint
Xing, Z., Cao, H., Zhang, M., Liu, J., Wu, J., Ren, F., Feng, K., Wang, Y., & Wang, X. (2023) · Research Square · doi:10.21203/rs.3.rs-2738695/v1
Self-citation
Additional file 5 of Molecular characterization, expression and functional analysis of acyl-CoA-binding protein gene family in maize (Zea mays)
Zhu, J., Li, W., Zhou, Y., Pei, L., Liu, J., Xia, X., Che, R., & Li, H. (2021) · Figshare · doi:10.6084/m9.figshare.14037904
Self-citation
Additional file 6 of Molecular characterization, expression and functional analysis of acyl-CoA-binding protein gene family in maize (Zea mays)
Zhu, J., Li, W., Zhou, Y., Pei, L., Liu, J., Xia, X., Che, R., & Li, H. (2021) · Figshare · doi:10.6084/m9.figshare.14037907
Self-citation
Additional file 3 of Molecular characterization, expression and functional analysis of acyl-CoA-binding protein gene family in maize (Zea mays)
Zhu, J., Li, W., Zhou, Y., Pei, L., Liu, J., Xia, X., Che, R., & Li, H. J. (2021) · Figshare · doi:10.6084/m9.figshare.14037898
Self-citation
Additional file 2 of Molecular characterization, expression and functional analysis of acyl-CoA-binding protein gene family in maize (Zea mays)
Zhu, J., Li, W., Zhou, Y., Pei, L., Liu, J., Xia, X., Che, R., & Li, H. (2021) · Figshare · doi:10.6084/m9.figshare.14037895
Self-citation
The apo-acyl coenzyme A binding protein of Leishmania major forms a unique ‘AXXA’ motif mediated dimer
Verma, S., Dangi, R. S., Rajak, M. K., Pal, R. K., & Sundd, M. (2024) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2024.141016
Prediction of Distant Metastasis of Lymph-Node-Negative Primary Breast Cancer From Gene Expression Profiling Using Cox-Boost Regression Model
Hamidi, O., Amini, P., Tapak, L., Beigi, Y. Z., Afshar, S., & Dinu, I. A. (2024) · Cancer Informatics · doi:10.1177/11769351241297493
Additional file 8 of Molecular characterization, expression and functional analysis of acyl-CoA-binding protein gene family in maize (Zea mays)
Zhu, J., Li, W., Zhou, Y., Pei, L., Liu, J., Xia, X., Che, R., & Li, H. (2021) · Figshare · doi:10.6084/m9.figshare.14037913
Self-citation
Additional file 1 of Metallothionein-3 is a multifunctional driver that modulates the development of sorafenib-resistant phenotype in hepatocellular carcinoma cells
Rodrigo, M. A. M., Michalkova, H., Jimenez, A. M. J., Petrlak, F., Do, T., Sivák, L., Haddad, Y., Kubickova, P., Rı́os, V. D. L., Casal, J. I., et al. (2024) · Figshare · doi:10.6084/m9.figshare.25572560
Additional file 4 of Molecular characterization, expression and functional analysis of acyl-CoA-binding protein gene family in maize (Zea mays)
Zhu, J., Li, W., Zhou, Y., Pei, L., Liu, J., Xia, X., Che, R., & Li, H. (2021) · Figshare · doi:10.6084/m9.figshare.14037901
Self-citation
Additional file 3 of ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrier
Yue, X., Qian, Y., Zhu, L., Gim, B., Bao, M., Jia, J., Jing, S., Wang, Y., Tan, C., Bottanelli, F., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16584263
Additional file 4 of ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrier
Yue, X., Qian, Y., Zhu, L., Gim, B., Bao, M., Jia, J., Jing, S., Wang, Y., Tan, C., Bottanelli, F., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16584266
Additional file 1 of ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrier
Yue, X., Qian, Y., Zhu, L., Gim, B., Bao, M., Jia, J., Jing, S., Wang, Y., Tan, C., Bottanelli, F., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16584257
Additional file 2 of ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrier
Yue, X., Qian, Y., Zhu, L., Gim, B., Bao, M., Jia, J., Jing, S., Wang, Y., Tan, C., Bottanelli, F., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16584260
Additional file 1 of Molecular characterization, expression and functional analysis of acyl-CoA-binding protein gene family in maize (Zea mays)
Zhu, J., Li, W., Zhou, Y., Pei, L., Liu, J., Xia, X., Che, R., & Li, H. (2021) · Figshare · doi:10.6084/m9.figshare.14037892
Self-citation
Additional file 7 of Molecular characterization, expression and functional analysis of acyl-CoA-binding protein gene family in maize (Zea mays)
Zhu, J., Li, W., Zhou, Y., Pei, L., Liu, J., Xia, X., Che, R., & Li, H. (2021) · Figshare · doi:10.6084/m9.figshare.14037910
Self-citation
Additional file 5 of ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrier
Yue, X., Qian, Y., Zhu, L., Gim, B., Bao, M., Jia, J., Jing, S., Wang, Y., Tan, C., Bottanelli, F., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16584269
Rôle du complexe VDAC1/TSPO1 au cours de l'érythropoïèse humaine, focus sur la mitophagie
Moras, M. (2020) · theses.fr (ABES) · doi:10.70675/a4c63cc2z949az4474zb1acz38e7f433fd35
Impact du stress périnatal chez le rongeur : évaluation comportementale et mécanismes d’action
Gazzo, G. (2020) · theses.fr (ABES) · doi:10.70675/6cf2a187z793az4bb8z81b6zf7e4e711cb51
Integrating dorsolateral prefrontal cortex multi-omics and GWAS summary data enhances gene-mapping of Parkinson’s diseasePreprint
Liu, Q., Tasaki, S., Bennett, D. A. A., Seyfried, N. T., Jager, P. L. D., Menon, V., Buchman, A. S., & Yang, J. (2026) · medRxiv · doi:10.64898/2026.05.23.26353951

Authors: Fan, J., Liu, J., Culty, M., & Papadopoulos, V.
Affiliations: McGill University Health Centre (CA)
Georgetown University Medical Center (US)
Corresponding author: Papadopoulos, Vassilios
ORCID: Fan, Jinjiang
Liu, Jun
Culty, Martine
Papadopoulos, Vassilios
Venue: Progress in Lipid Research
Publisher: Elsevier BV
Published: 2010-07
Volume: 49
Issue: 3
Pages: 218-234
ISSN: 0163-7827 (ISSN-L)
DOI: 10.1016/j.plipres.2009.12.003
PMC: PMC2873055
OpenAlex: W2054877611
Cited by: 142
References: 110
Citations by year: 2026: 1 · 2025: 2 · 2024: 9 · 2023: 1 · 2022: 9 · 2021: 19 · 2020: 12 · 2019: 9 · 2018: 7 · 2017: 7 · 2016: 10 · 2015: 21 · 2014: 8 · 2013: 5 · 2012: 11
FWCI: 3.64
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Progress in Lipid Research (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD37031, R01HD037031)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Kinase Regulation and GTPase Signaling
Keywords: ACBD3, Golgi apparatus, steroidogenesis, apoptosis, neurogenesis, embryonic development, asymmetric cell division, cancer, molecular endocrinology, neurology, stem cell biology
MeSH terms: Golgi Apparatus, Humans, Membrane Proteins, Signal Transduction, Apoptosis, Protein Structure, Tertiary, Embryonic Development, Adaptor Proteins, Signal Transducing, Neurogenesis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Acyl-coenzyme A binding domain containing 3 (ACBD3; PAP7; GCP60): An emerging signaling molecule

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks