The DOI matches its Crossref record; 110 of the 110 references it cites were found in a registry or an index.
Acyl-coenzyme A binding domain containing 3 (ACBD3; PAP7; GCP60): An emerging signaling molecule
Open accessAbstract
Golgi body-mediated signaling has been linked to its fragmentation and regeneration during the mitotic cycle of the cell. During this process, Golgi-resident proteins are released to the cytosol and interact with other signaling molecules to regulate various cellular processes. Acyl-coenzyme A binding domain containing 3 protein (ACBD3) is a Golgi protein involved in several signaling events. ACBD3 protein was previously known as peripheral-type benzodiazepine receptor and cAMP-dependent protein kinase associated protein 7 (PAP7), Golgi complex-associated protein of 60kDa (GCP60), Golgi complex-associated protein 1 (GOCAP1), and Golgi phosphoprotein 1 (GOLPH1). In this review, we present the gene ontology of ACBD3, its relations to other Acyl-coenzyme A binding domain containing (ACBD) proteins, and its biological function in steroidogenesis, apoptosis, neurogenesis, and embryogenesis. We also discuss the role of ACBD3 in asymmetric cell division and cancer. New findings about ACBD3 may help understand this newly characterized signaling molecule and stimulate further research into its role in molecular endocrinology, neurology, and stem cell biology.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“ACBD5 is one of the seven members of the mammalian acyl-CoA binding domain-containing protein (ACBP) family characterized by an N-terminal acyl-CoA binding domain (ACBD) (15).”
From Deficiency of a Retinal Dystrophy Protein, Acyl-CoA Binding Domain-containing 5 (ACBD5), Impairs Peroxisomal β-Oxidation of Very-long-chain Fatty Acids (2017) · cites this paper as [15]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Stem cells, cancer, and cancer stem cells
Reya, T., Morrison, S. J., Clarke, M. F., & Weissman, I. L. (2001) · Nature · doi:10.1038/35102167 · Cited by 9,738
Asymmetric and symmetric stem-cell divisions in development and cancer
Morrison, S. J., & Kimble, J. E. (2006) · Nature · doi:10.1038/nature04956 · Cited by 1,457
Papadopoulos, V., Baraldi, M., Guilarte, T. R., Knudsen, T. B., Lacapère, J.-J., Lindemann, P., Norenberg, M. D., Nutt, D., Weizman, A., Zhang, M.-R., et al. (2006) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2006.06.005 · Cited by 1,389
Self-citationRole of long-chain fatty acyl-CoA esters in the regulation of metabolism and in cell signalling
Færgeman, N. J., & Knudsen, J. (1997) · Biochemical Journal · doi:10.1042/bj3230001 · Cited by 681
Guidotti, A., Forchetti, C., Corda, M. G., Konkel, D. A., Bennett, C. D., & Costa, E. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.11.3531 · Cited by 646
Fatty acid oxidation is a dominant bioenergetic pathway in prostate cancer
Liu, Y. (2006) · Prostate Cancer and Prostatic Diseases · doi:10.1038/sj.pcan.4500879 · Cited by 433
PAPADOPOULOS, V. (1993) · Endocrine Reviews · doi:10.1210/edrv-14-2-222 · Cited by 417
Self-citationCaspase-2 Is Localized at the Golgi Complex and Cleaves Golgin-160 during Apoptosis
Mancini, M., Machamer, C. E., Roy, S., Nicholson, D. W., Thornberry, N. A., Casciola-Rosen, L. A., & Rosen, A. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.149.3.603 · Cited by 379
gp25L/emp24/p24 Protein Family Members of the cis- Golgi Network Bind Both COP I and II Coatomer
Dominguez, M., Dejgaard, K., Füllekrug, J., Dahan, S., Fazel, A., Paccaud, J., Thomas, D. Y., Bergeron, J. J. M., & Nilsson, T. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.140.4.751 · Cited by 335
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
Petersen, P. H., Zou, K., Hwang, J. K., Jan, Y. N., & Zhong, W. (2002) · Nature · doi:10.1038/nature01124 · Cited by 330
Research works printed but not linked: 4
- [32]Jolly CA Wilton DC Schroeder F Microsomal fatty acyl-CoA transacylation and hydrolysis: fatty acyl-CoA species dependent modulation by liver fatty acyl-CoA binding proteins BBA-Mol Cell Biol L 2000 1483 185 197 10601707
- [43]Scanlan MJ Gordan JD Williamson B Stockert E Bander NH Jongeneel V Gure AO Jaeger D Jaeger E Knuth A Antigens recognized by autologous antibody in patients with renal-cell carcinoma Int J Cancer 1999 83 456 464 10508479
- [48]Groszer M Erickson R Scripture-Adams DD Dougherty JD Le BJ Zack JA Geschwind DH Liu X Kornblum HI Wu H PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry Proc Natl Acad Sci U S A 2006 103 111 116 16373498 PMC1325011
- [96]Fang M Jaffrey SR Sawa A Ye K Luo X Snyder SH Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON Neuron 2000 28 183 193 11086993
Cited by
Sorted by citations
Rupprecht, R., Papadopoulos, V., Rammes, G., Baghai, T. C., Fan, J., Akula, N., Groyer, G., Adams, D., & Schumacher, M. (2010) · Nature Reviews Drug Discovery · doi:10.1038/nrd3295 · Cited by 930
Self-citationSteroid hormone synthesis in mitochondria
Miller, W. L. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.04.014 · Cited by 510
Role of mitochondria in steroidogenesis
Papadopoulos, V., & Miller, W. L. (2012) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2012.05.002 · Cited by 261
Self-citationRole of the steroidogenic acute regulatory protein in health and disease
Manna, P. R., Stetson, C. L., Slominski, A. T., & Pruitt, K. (2015) · Endocrine · doi:10.1007/s12020-015-0715-6 · Cited by 218
ACBD3‐mediated recruitment of PI4KB to picornavirus RNA replication sites
Sasaki, J. D., Ishikawa, K., Arita, M., & Taniguchi, K. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.429 · Cited by 186
Metadata
- Authors
- Fan, J., Liu, J., Culty, M., & Papadopoulos, V.
- Affiliations
- McGill University Health Centre (CA)
- Georgetown University Medical Center (US)
- Corresponding author
- Papadopoulos, Vassilios
- Venue
- Progress in Lipid Research
- Publisher
- Elsevier BV
- Published
- 2010-07
- Volume
- 49
- Issue
- 3
- Pages
- 218-234
- ISSN
- 0163-7827 (ISSN-L)
- PMC
- PMC2873055
- OpenAlex
- W2054877611
- Cited by
- 142
- References
- 110
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 9 · 2023: 1 · 2022: 9 · 2021: 19 · 2020: 12 · 2019: 9 · 2018: 7 · 2017: 7 · 2016: 10 · 2015: 21 · 2014: 8 · 2013: 5 · 2012: 11
- FWCI
- 3.64
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Progress in Lipid Research (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD37031, R01HD037031)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Kinase Regulation and GTPase Signaling
- Keywords
- ACBD3, Golgi apparatus, steroidogenesis, apoptosis, neurogenesis, embryonic development, asymmetric cell division, cancer, molecular endocrinology, neurology, stem cell biology
- MeSH terms
- Golgi Apparatus, Humans, Membrane Proteins, Signal Transduction, Apoptosis, Protein Structure, Tertiary, Embryonic Development, Adaptor Proteins, Signal Transducing, Neurogenesis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
