Protective effects and mechanisms of sirtuins in the nervous system

MicroRNAs: Target Recognition and Regulatory Functions

Bartel, D. P. (2009) · Cell · doi:10.1016/j.cell.2009.01.002 · Cited by 20,068

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

Rosen, D. R., Siddique, T., Patterson, D., Figlewicz, D. A., Sapp, P., Hentati, A., Donaldson, D., Goto, J., O'Regan, J. P., Deng, H.-X., et al. (1993) · Nature · doi:10.1038/362059a0 · Cited by 7,062

Resveratrol improves health and survival of mice on a high-calorie diet

Baur, J. A., Pearson, K. J., Price, N. L., Jamieson, H. A., Lerin, C., Kalra, A., Prabhu, V. V., Allard, J. S., Lopez-Lluch, G., Lewis, K., et al. (2006) · Nature · doi:10.1038/nature05354 · Cited by 4,290

A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., & Spiegelman, B. M. (1998) · Cell · doi:10.1016/s0092-8674(00)81410-5 · Cited by 3,864

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Howitz, K. T., Bitterman, K. J., Cohen, H. Y., Lamming, D. W., Lavu, S., Wood, J. G., Zipkin, R. E., Chung, P., Kisielewski, A., Zhang, L.-L., et al. (2003) · Nature · doi:10.1038/nature01960 · Cited by 3,796

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

Imai, S.-I., Armstrong, C. M., Kaeberlein, M., & Guarente, L. (2000) · Nature · doi:10.1038/35001622 · Cited by 3,510

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

Brunet, A., Sweeney, L. B., Sturgill, J. F., Chua, K. F., Greer, P. L., Lin, Y., Tran, H., Ross, S. E., Mostoslavsky, R., Cohen, H. Y., et al. (2004) · Science · doi:10.1126/science.1094637 · Cited by 3,239

Histone Deacetylases Exert Class-Specific Roles in Conditioning the Brain and Heart Against Acute Ischemic Injury

Aune, S. E., Herr, D. J., Kutz, C. J., & Menick, D. R. (2015) · Frontiers in Neurology · doi:10.3389/fneur.2015.00145 · Cited by 31

Signaling pathways leading to ischemic mitochondrial neuroprotection

Thompson, J. W., Narayanan, S., Koronowski, K. B., Morris-Blanco, K. C., Dave, K. R., & Pérez‐Pinzón, M. A. (2014) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-014-9574-8 · Cited by 32

Recovery of Olfactory Function After Excitotoxic Lesion of the Olfactory Bulbs Is Associated with Increases in Bulbar SIRT1 and SIRT4 Expressions

Marı́n, C., Langdon, C., Alobid, I., Fuentes, M., Bonastre, M., & Mullol, J. (2019) · Molecular Neurobiology · doi:10.1007/s12035-019-1472-y · Cited by 31

Sirt1 improves functional recovery by regulating autophagy of astrocyte and neuron after brain injury

Zhang, Z., Li, D., Xu, L., & Li, H.-P. (2019) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2019.05.005 · Cited by 33

Biochemical Characterization of Sirtuin 6 in the Brain and Its Involvement in Oxidative Stress Response

Cardinale, A., de Stefano, M. C., Mollinari, C., Racaniello, M., Garaci, E., & Merlo, D. (2014) · Neurochemical Research · doi:10.1007/s11064-014-1465-1 · Cited by 32

Metformin Alleviates Delayed Hydrocephalus after Intraventricular Hemorrhage by Inhibiting Inflammation and Fibrosis

Cao, Y. L., Liu, C., Li, G., Gao, W., Tang, H. J., Fan, S., Tang, X., Zhao, L., Wang, H., Peng, A., et al. (2022) · Translational Stroke Research · doi:10.1007/s12975-022-01026-3 · Cited by 31

Role of Citicoline in Patients With Mild Cognitive Impairment

Bermejo, P. E., Dorado, R., & Zea‐Sevilla, M. A. (2023) · Neuroscience Insights · doi:10.1177/26331055231152496 · Cited by 34

Docking and binding free energy calculations of sirtuin inhibitors

Karaman, B., & Sippl, W. (2015) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2015.02.045 · Cited by 30

Effects of Resveratrol and trans-3,5,4'-Trimethoxystilbene on Glutamate-Induced Cytotoxicity, Heme Oxygenase-1, and Sirtuin 1 in HT22 Neuronal Cells

Kim, D. W., Kim, Y., Kang, S. D., Han, Y., & Pae, H. (2012) · Biomolecules & Therapeutics · doi:10.4062/biomolther.2012.20.3.306 · Cited by 30

Ginkgetin aglycone attenuates neuroinflammation and neuronal injury in the rats with ischemic stroke by modulating STAT3/JAK2/SIRT1

Xu, B. Y., He, X., Sui, Y., Wang, X., Wang, X., Ren, L., & Zhai, Y.-X. (2019) · Folia Neuropathologica · doi:10.5114/fn.2019.83827 · Cited by 30

Hydrogen Sulfide Prevents Sleep Deprivation-Induced Hippocampal Damage by Upregulation of Sirt1 in the Hippocampus

Zuo, J.-X., Li, M., Jiang, L., Lan, F., Tang, Y.-Y., Kang, X., Zou, W., Wang, C., Zhang, P., & Tang, X. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00169 · Cited by 30

SIRT1 regulates O-GlcNAcylation of tau through OGT

Lu, S., Yin, X., Wang, J., Gu, Q., Huang, Q., Jin, N., Chu, D., Xu, Z., Liu, F., & Qian, W. (2020) · Aging · doi:10.18632/aging.103062 · Cited by 31

Regulation of sirtuin expression in autoimmune neuroinflammation: Induction of SIRT1 in oligodendrocyte progenitor cells

Prozorovski, T., Ingwersen, J., Lukas, D., Göttle, P., Koop, B. E., Graf, J., Schneider, R., Franke, K., Schumacher, S., Britsch, S., et al. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.04.007 · Cited by 30

Patchouli alcohol ameliorates the learning and memory impairments in an animal model of Alzheimer's disease via modulating SIRT1

Xu, Q., Su, Z., Hu, Z. J., Yang, W., Xian, Y., & Lin, Z. (2022) · Phytomedicine · doi:10.1016/j.phymed.2022.154441 · Cited by 30

Ferulic Acid Activates SIRT1-Mediated Ferroptosis Signaling Pathway to Improve Cognition Dysfunction in Wilson’s Disease

Wang, X., Shao, N., Zhang, X., Chen, H., Chang, Z., Xie, D., & Zhang, J. (2023) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s443278 · Cited by 30

Anoectochilus roxburghii flavonoids extract ameliorated the memory decline and reduced neuron apoptosis via modulating SIRT1 signaling pathway in senescent mice

Zeng, Z., Chen, C., SiTu, Y., Shen, Z., Chen, Y., Zhang, Z., Tang, C., & Jiang, T. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115361 · Cited by 27

Resveratrol delays Wallerian degeneration in a NAD+ and DBC1 dependent manner

Calliari, A. J., Bobba, N., Escande, C., & Chini, E. N. (2013) · Experimental Neurology · doi:10.1016/j.expneurol.2013.11.013 · Cited by 28

Resveratrol ameliorates lipopolysaccharide-induced anxiety-like behavior by attenuating YAP-mediated neuro-inflammation and promoting hippocampal autophagy in mice

Tian, Q., Fan, X., Ma, J., Han, Y., Li, D., Jiang, S., Zhang, F., Guang, H., Shan, X., Chen, R., et al. (2020) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2020.115261 · Cited by 28

Over-expression of the Sirt3 sirtuin Protects neuronally differentiated PC12 Cells from degeneration induced by oxidative stress and trophic withdrawal

Shulyakova, N., Sidorova‐Darmos, E., Fong, J., Zhang, G., Mills, L. R., & Eubanks, J. H. (2014) · Brain Research · doi:10.1016/j.brainres.2014.08.066 · Cited by 26

Sirt1 attenuates astrocyte activation via modulating Dnajb1 and chaperone-mediated autophagy after closed head injury

Zhang, Z., Zhang, X., Wu, X., Zhang, Y., Lu, J., & Li, D. (2022) · Cerebral Cortex · doi:10.1093/cercor/bhac007 · Cited by 27

Sirtuins, a key regulator of ageing and age-related neurodegenerative diseases

Bhatt, V., & Tiwari, A. K. (2023) · International Journal of Neuroscience · doi:10.1080/00207454.2022.2057849 · Cited by 28

Effects of Aluminium on Long‐Term Memory in Rats and on SIRT 1 Mediating the Transcription of CREB ‐Dependent Gene in Hippocampus

Yan, D., Jin, C., Cao, Y., Wang, L., Lu, X., Yang, J., Wu, S., & Cai, Y. (2017) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.12798 · Cited by 26

High glucose concentration suppresses a SIRT2 regulated pathway that enhances neurite outgrowth in cultured adult sensory neurons

Schartner, E., Sabbir, M. G., Saleh, A. J., Silva, R. V., Chowdhury, S. R., Smith, D. R., & Fernyhough, P. (2018) · Experimental Neurology · doi:10.1016/j.expneurol.2018.08.001 · Cited by 30

Mild hypothermia improves neurological outcome in mice after cardiopulmonary resuscitation through Silent Information Regulator 1-actviated autophagy

Wei, H., Yin, M., Lu, Y., Yang, Y., Li, B., Liao, X., Dai, G., Jing, X., Xiong, Y., & Hu, C. (2019) · Cell Death Discovery · doi:10.1038/s41420-019-0209-z · Cited by 26

Potential role of nucleoside diphosphate kinase in myricetin-induced selective apoptosis in colon cancer HCT-15 cells

Lee, J. H., Choi, Y. J., Park, S., & Nam, M. J. (2018) · Food and Chemical Toxicology · doi:10.1016/j.fct.2018.04.053 · Cited by 25

Sirtuins in Multiple Sclerosis: The crossroad of neurodegeneration, autoimmunity and metabolism

Foolad, F., Khodagholi, F., & Javan, M. (2019) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2019.06.004 · Cited by 26

Gastrodin alleviates Tourette syndrome via Nrf‐2/HO‐1/HMGB1/NF‐кB pathway

Long, H., Ruan, J., Mengjiao, Z., Wang, C., & Huang, Y. (2019) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.22389 · Cited by 24

MiR-138/SIRT1 axis is implicated in impaired learning and memory abilities of cerebral ischemia/reperfusion injured rats

Tian, F., Yuan, C., & Yue, H. (2018) · Experimental Cell Research · doi:10.1016/j.yexcr.2018.03.042 · Cited by 22

Mitochondrial sirtuins – a new therapeutic target for repair and protection in multiple sclerosis

Rice, C. M., Sun, M., Kemp, K. C., Gray, E., Wilkins, A., & Scolding, N. J. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2012.08150.x · Cited by 25

Flavonoids as Sirtuin Modulators

Şenol, F. S., Eren, G., & Orhan, İ. E. (2022) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026622666220422094744 · Cited by 24

A Retrospective Study on the Benefits of Combined Citicoline, Memantine, and Acetylcholinesterase Inhibitor Treatments in Older Patients Affected with Alzheimer’s Disease

Castagna, A., Fabbo, A., Manzo, C., Lacava, R., Ruberto, C., & Ruotolo, G. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201211 · Cited by 22

The CITIMEM study: A pilot study. Optimizing pharmacological treatment in dementia

Gareri, P., Cotroneo, A. M., Orsitto, G., & Putignano, S. (2020) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2020.104073 · Cited by 21

Multifaced role of protein deacetylase sirtuins in neurodegenerative disease

Gupta, R. V., Ambasta, R. K., & Kumar, P. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.10.047 · Cited by 20

Research Progress on the Role of Sirtuin 1 in Cerebral Ischemia

Fangma, Y., Wan, H., Shao, C., Jin, L., & He, Y. G. (2022) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-022-01288-3 · Cited by 21

Neuroprotection in Multiple Sclerosis: A Therapeutic Approach

Maghzi, A., Minagar, A., & Waubant, E. L. (2013) · CNS Drugs · doi:10.1007/s40263-013-0093-7 · Cited by 20

Senescence in adipose-derived stem cells and its implications in nerve regeneration

Mantovani, C., Terenghi, G., & Magnaghi, V. (2014) · Neural Regeneration Research · doi:10.4103/1673-5374.125324 · Cited by 20

Chikusetsu saponin IVa attenuates isoflurane-induced neurotoxicity and cognitive deficits via SIRT1/ERK1/2 in developmental rats.

Fang, X., Han, Q., Li, S., Zhao, Y., & Luo, A. (2017) · Europe PMC (PubMed Central) · Cited by 20

Rhynchophylline Attenuates Neurotoxicity in Tourette Syndrome Rats

Hongyan, L., Mengjiao, Z., Chunyan, W., & Yaruo, H. (2019) · Neurotoxicity Research · doi:10.1007/s12640-019-00059-1 · Cited by 19

A comprehensive review of cycloastragenol: Biological activity, mechanism of action and structural modifications

He, M., Wang, K., Che, H., Wang, H., Yang, K., Zhang, G., Yao, J., & Wang, J. (2022) · European Journal of Medicinal Chemistry Reports · doi:10.1016/j.ejmcr.2022.100060 · Cited by 18

Inhibition of Sirtuin 6 Induces Neuroblastoma Differentiation

Song, H. Y., Rellinger, E. J., Park, S., Paul, P., Qiao, J., Vasilopoulos, A., Özden, Ö., Gius, D. R., & Chung, D. H. (2018) · Anticancer Research · doi:10.21873/anticanres.12268 · Cited by 19

Cycloastragenol Confers Cerebral Protection after Subarachnoid Hemorrhage by Suppressing Oxidative Insults and Neuroinflammation via the SIRT1 Signaling Pathway

Lin, W., Yao, H., Lai, J., Zeng, Y., Guo, X., Lin, S., Hu, W., Chen, J., & Chen, X. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/3099409 · Cited by 18

Dietary Restriction Affects Neuronal Response Property and GABA Synthesis in the Primary Visual Cortex

Yang, J., Wang, Q., He, F., Ding, Y., Sun, Q., Hua, T., & Xi, M.-M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0149004 · Cited by 16

SIRT1 Activation

Vellimana, A. K., Diwan, D., Clarke, J. V., Gidday, J. M., & Zipfel, G. J. (2018) · Neurosurgery · doi:10.1093/neuros/nyy201 · Cited by 16

Role of SIRT1 in Isoflurane Conditioning-Induced Neurovascular Protection against Delayed Cerebral Ischemia Secondary to Subarachnoid Hemorrhage

Liu, M., Jayaraman, K., Giri, T. K., Zipfel, G. J., & Athiraman, U. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22084291 · Cited by 17

Role of nucleolar dysfunction in neurodegenerative disorders: a game of genes?

Parlato, R., & Bierhoff, H. (2015) · AIMS molecular science · doi:10.3934/molsci.2015.3.211 · Cited by 16

Association of a SIRT1 polymorphism with changes of gray matter volume in patients with first-episode medication-naïve major depression

Dai, N., Yuqi, C., Zonglin, S., Chenglong, D., Na, L., Liu, F., Zhou, C., & Xu, X. (2020) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2020.111101 · Cited by 18

Activation of Sirtuin‐1 by Pinocembrin Treatment Contributes to Reduced Early Brain Injury after Subarachnoid Hemorrhage

Zeng, Y., Fang, Z., Lai, J., Wu, Z., Lin, W., Yao, H., Hu, W., Chen, J., Guo, X., & Chen, X. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/2242833 · Cited by 16

Modulation of Sirtuins to address aging related disorders through the use of selected phytochemicals

Wang, J., Ren, Y., & Qu, S. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.156648 · Cited by 16

FGF10 protects against LPS-induced epithelial barrier injury and inflammation by inhibiting SIRT1-ferroptosis pathway in acute lung injury in mice.

Lin, L.-D., Yang, L., Wang, N.-N., Chen, S., Du, X.-T., Chen, R., Zhang, H.-Y., & Kong, X.-X. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.111426 · Cited by 16

Resveratrol and 1,25-dihydroxyvitamin D decrease Lingo-1 levels, and improve behavior in harmaline-induced Essential tremor, suggesting potential therapeutic benefits

Pirmoradi, Z., Nakhaie, M., Ranjbar, H., Kalantar-Neyestanaki, D., Kohlmeier, K. A., Asadi‐Shekaari, M., Hassanshahi, A., & Shabani, M. (2024) · Scientific Reports · doi:10.1038/s41598-024-60518-4 · Cited by 16

The effects simultaneous inhibition of dipeptidyl peptidase-4 and P2X7 purinoceptors in an in vivo Parkinson’s disease model

Jamali-Raeufy, N., Mojarrab, Z., Baluchnejadmojarad, T., Roghani, M., Fahanik‐Babaei, J., & Goudarzi, M. (2020) · Metabolic Brain Disease · doi:10.1007/s11011-020-00538-x · Cited by 15

Expression Profiles of SIRT1 and APP Genes in Human Neuroblastoma SK-N-SH Cells Treated with Two Epigenetic Agents

Hou, Y., Wang, F., Cheng, L., Luo, T., Xu, J., & Wang, H. (2016) · Neuroscience Bulletin · doi:10.1007/s12264-016-0052-7 · Cited by 15

SIRT1 Regulates Tau Expression and Tau Synaptic Pathology

Yin, X., Zhou, Z., Qiu, Y., Fan, X., Zhao, C., Bao, J., Liu, C., Liu, F., & Qian, W. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-215118 · Cited by 15

Sirtuins as Potential Targets for Neuroprotection: Mechanisms of Early Brain Injury Induced by Subarachnoid Hemorrhage

Lei, K., Wu, R., Wang, J., Lei, X., Zhou, E., Fan, R., & Gong, L. (2023) · Translational Stroke Research · doi:10.1007/s12975-023-01191-z · Cited by 14

Lipopolysaccharide aggravated DOI-induced Tourette syndrome: elaboration for recurrence of Tourette syndrome

Hongyan, L., Si, Z., Chunyan, W., & Pan, Q. (2017) · Metabolic Brain Disease · doi:10.1007/s11011-017-0084-3 · Cited by 12

Therapeutic Applications of Resveratrol in Hepatic Encephalopathy through Its Regulation of the Microbiota, Brain Edema, and Inflammation

Kim, Y., & Song, J. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10173819 · Cited by 12

The effects of exercise on kidney injury: the role of SIRT1

Sabet, N., Soltani, Z., & Khaksari, M. (2022) · Molecular Biology Reports · doi:10.1007/s11033-022-07122-9 · Cited by 12

Deacetylase SIRT2 Inhibition Promotes Microglial M2 Polarization Through Axl/PI3K/AKT to Alleviate White Matter Injury After Subarachnoid Hemorrhage

Yuan, K., Wu, Q., Yao, Y., Shao, J., Zhu, S., Yang, J., Sun, Q. L., Zhao, J., Xu, J., Wu, P., et al. (2024) · Translational Stroke Research · doi:10.1007/s12975-024-01282-5 · Cited by 13

Sirtuins and Neurodegeneration

Dönmez, G. (2017) · Journal of Neurology and Neuromedicine · doi:10.29245/2572.942x/2017/1.1168 · Cited by 11

Interaction between Sirtuin 1 (SIRT1) polymorphisms and childhood maltreatment on aggression risk in Chinese male adolescents

Wang, M., Peng, C., Chang, H., Yu, M., Rong, F., & Yu, Y. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.04.063 · Cited by 10

Myocardial infarction-induced anxiety-like behavior is associated with epigenetic alterations in the hippocampus of rat

Zhou, Y., Tian, Q., Zheng, C., Yang, J., Fan, J., & Shentu, Y. (2020) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2020.08.023 · Cited by 10

Citicoline: A Cholinergic Precursor with a Pivotal Role in Dementia and Alzheimer’s Disease

Gareri, P., Cotroneo, A. M., Montella, R., Gaglianone, M., & Putignano, S. (2024) · Journal of Alzheimer s Disease · doi:10.3233/jad-240497 · Cited by 9

Ginseng and Polygonum multiflorum formula protects brain function in Alzheimer’s disease

Liu, J., Wei, F., Wang, Y., Liu, J., Xu, B., Ma, S., & Yang, J.-B. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1461177 · Cited by 9

Role of NAD+ and FAD in Ischemic Stroke Pathophysiology: An Epigenetic Nexus and Expanding Therapeutic Repertoire

Narne, P., & Phanithi, P. B. (2022) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-022-01287-4 · Cited by 9

Neuroprotective Strategies and Cell-Based Biomarkers for Manganese-Induced Toxicity in Human Neuroblastoma (SH-SY5Y) Cells

Cahill, C. M., Sarang, S. S., Bakshi, R., Xia, N., Lahiri, D. K., & Rogers, J. T. (2024) · Biomolecules · doi:10.3390/biom14060647 · Cited by 8

Regulation of gene expression in ischemic preconditioning in the brain.

Yang, T., Li, Q., & Zhang, F. (2017) · PubMed · Cited by 8

Gongjin-Dan Enhances Neurite Outgrowth of Cortical Neuron by Ameliorating H2O2-Induced Oxidative Damage via Sirtuin1 Signaling Pathway

Kim, H., Jeon, W., Hong, J., Lee, J., Yeo, C., Lee, Y. J., Baek, S. H., & Ha, I. (2021) · Nutrients · doi:10.3390/nu13124290 · Cited by 8

Electro-Acupuncture Therapy Alleviates Post-Stroke Insomnia by Regulating Sirt1 and the Nrf2-ARE Pathway

Wang, Y., Chen, Y., Yang, J., Sun, W., & Zhang, X.-N. (2025) · NeuroMolecular Medicine · doi:10.1007/s12017-025-08862-0 · Cited by 8

Batroxobin inhibits astrocyte activation following nigrostriatal pathway injury

Li, D., Zhang, Z., & Bao, X. (2020) · Neural Regeneration Research · doi:10.4103/1673-5374.295343 · Cited by 7

Critical role of VGLL4 in the regulation of chronic normobaric hypoxia‐induced pulmonary hypertension in mice

Tian, Q., Fan, X., Ma, J., Li, D., Han, Y., Yin, X., Wang, H., Huang, T., Wang, Z., Shentu, Y., et al. (2021) · The FASEB Journal · doi:10.1096/fj.202002650rr · Cited by 7

Novel Injury Scoring Tool for Assessing Brain Injury following Neonatal Hypoxia-Ischemia in Mice

Özaydın, B., Bicki, E., Taparli, O. E., Sheikh, T. Z., Schmidt, D. K., Yapici, S., Hackett, M., Karahan-Keles, N., Eickhoff, J. C., Corcoran, K., et al. (2022) · Developmental Neuroscience · doi:10.1159/000525244 · Cited by 7

Huntington’s disease: Towards disease modification – Gaps and bridges, facts and opinions

Reilmann, R. (2012) · Basal Ganglia · doi:10.1016/j.baga.2012.09.004 · Cited by 7

Structure-Based Design and Computational Studies of Sirtuin Inhibitors

Karaman, B., Jung, M., & Sippl, W. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802808-7.00011-3 · Cited by 7

Caloric restriction in mice improves short-term recognition memory and modifies the neuroinflammatory response in the hippocampus of male adult offspring

de Oliveira, T. Q., de Moura, A. C., Feistauer, V., Damiani, R. M., Braga, M. F., Almeida, S., Guedes, R. P., & Giovenardi, M. (2022) · Behavioural Brain Research · doi:10.1016/j.bbr.2022.113838 · Cited by 7

Renalase Challenges the Oxidative Stress and Fibroproliferative Response in COVID‐19

Stojanović, D. R., Stojanović, M., Milenković, J., Veličkov, A., Ignjatović, A., & Milojković, M. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/4032704 · Cited by 5

Interleukin-10 chimeric protein to protect transplanted neural progenitor cells from immune responses

Nakaji‐Hirabayashi, T., & Kitano, H. (2014) · Journal of Materials Chemistry B · doi:10.1039/c4tb01413h · Cited by 4

An Overview of Combination Treatment with Citicoline in Dementia

Gareri, P., Veronese, N., & Cotroneo, A. M. (2021) · Reviews on Recent Clinical Trials · doi:10.2174/1574887117666211221170344 · Cited by 4

Resveratrol and the Human Retina

Pintea, A., & Rugină, D. O. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815245-4.00008-9 · Cited by 4

Analysis of rs7895833 polymorphism of SIRT1 gene and its influence on the risk occurrence and progression of neurodegenerative disease, such as primary open-angle glaucoma in a Polish population

Siwak, M., Maślankiewicz, M., Nowak-Zduńczyk, A., Filipek, B., Wojtczak, R., Radek, M., Kucharska, E., Szaflik, J., Szaflik, J. P., & Majsterek, I. (2022) · Journal of Pre-Clinical and Clinical Research · doi:10.26444/jpccr/157149 · Cited by 3

The Effects of Sirtuin Activators on Cerebral White Matter, Redox Biomarkers, and Imaging Findings in Aging Brain

Kahraman, A. N., & Toklu, H. Z. (2021) · Healthy ageing and longevity · doi:10.1007/978-3-030-84965-8_14 · Cited by 5

Resveratrol and the Human Retina

Pintea, A., & Rugină, D. O. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-401717-7.00049-6 · Cited by 4

The metabolic-epigenetic interface: lysine succinylation orchestrates bidirectional crosstalk in neurodegenerative disorders

Fanglei, C. H. A. I., Liu, C., Liu, Y., & Zou, W. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2025.1678595 · Cited by 3

From Neuroinflammation to Neuroprotection: Focus on Potential New Therapeutic Targets in Cognitive Impairment

Gareri, P., Cotroneo, A. M., Gareri, P., & Manfredi, V. G. L. (2020) · Neurology and Neurobiology · doi:10.31487/j.nnb.2020.02.10 · Cited by 3

Caloric Restriction Attenuated Nerve Damages Mediated Through SIRT-1—a Study Using Nerve Crush Injury Model in Rats

Sheu, M., Pan, L.-Y., Pan, S., Chen, Y., Sheehan, J., You, W.-C., Wang, C., & Pan, H.-C. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-04786-9 · Cited by 2

Mechanism study on the attenuation of cerebral ischemia–reperfusion injury by LBP extract through regulation of SIRT1/PGC-1α axis

Niu, Q., Peng, J., Zhou, Y., Li, X., Liu, O., Cheng, X., Liu, P., Hei, C., & Yang, X. C. (2025) · Translational Neuroscience · doi:10.1515/tnsci-2025-0377 · Cited by 2

SIRT1–FOXO1 Signaling in Cancer

Abdulkhaliq, A. A., Khan, J., Ajoolabady, A., Praticò, D., Bahijri, S., Tuomilehto, J., Borai, A., Kim, B., Zhou, Y., & Ren, J. T. (2025) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.70553 · Cited by 2

Kaempferide and Norbergenin avert aluminium chloride-induced amyloid β accumulation and neurocognitive shutdown via oxidative and apoptotic mechanisms

Nalla, S., Ganta, S., Bukke, S. P. N., Bandaru, N., Onohuean, H., & Alagbonsi, A. I. (2025) · International Journal of Immunopathology and Pharmacology · doi:10.1177/03946320251343687 · Cited by 2

SRT1720 ameliorates LPS-induced depressive-like behaviors in mice and activates Parkin-mediated mitophagy

Sun, L., Li, C., Shi, J., Zeng, W., Wu, L., Wan, S., & Wang, Y. (2025) · BMC Neuroscience · doi:10.1186/s12868-025-00968-2 · Cited by 2

Retinal Neuroprotective Effect of Sirtuins

Mimura, T., Noma, H., Funatsu, H., Aki, & Matsubara, M. (2014) · Cited by 2

Epigenetic role of sirtuins in neurodegenerative brain disorders

Khanna, A., Anamika, A., & Trigun, S. K. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-814118-2.00009-4 · Cited by 3

Resveratrol, SIRT1, oxidative stress, and brain aging

Sarubbo, F., Tejada, S., Esteban, S., Jiménez‐García, M., & Moranta, D. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818698-5.00033-x · Cited by 2

Sirtuin Modulators and Brain Aging

Toklu, H. Z., & Ginory, A. (2018) · Springer eBooks · doi:10.1007/978-981-13-1699-9_9 · Cited by 2

The CITIDEMAGE Study: Combined Treatment with a Cholinergic Precursor in Dementia Patients

Gareri, P., Cotroneo, A. M., Orsitto, G., Veronese, N., & Putignano, S. (2022) · OBM Geriatrics · doi:10.21926/obm.geriatr.2201193 · Cited by 1

The evaluation of gene expression and enzyme activity of SIRT1 in peripheral blood mononuclear cells isolated from patients with relapsing-remitting multiple sclerosis

Emamgholipour, S., Sahraian, M. A., Shapourizadeh, S., & Alemzadeh‐Ansari, M. J. (2016) · Medical Laboratory Sciences · doi:10.22037/amls.v2i1.11927

Некоторые аспекты лечения когнитивных нарушений: цитиколин - фармакологические характеристики, возможные преимущества, аспекты применения

Трофимова, Н. В., Preobrazhenskaya, I. S., & Ya, A. (2015)

Genes, Aging, and Parkinson’s Disease

Milanese, C., & Mastroberardino, P. G. (2017) · Royal Society of Chemistry eBooks · doi:10.1039/9781782622888-00389

Sirtuins as key players in aging and kidney dysfunction

Perico, L., & Benigni, A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-814118-2.00013-6

Multimodal treatment strategies in Huntington’s disease

Dutta, R. (2021) · Journal of Neuroscience and Neurological Disorders · doi:10.29328/journal.jnnd.1001054

Neuroprotection induced by catechins in aging

Ramis, M. R., Sarubbo, F., Moranta, D., Tejada, S., Jiménez‐García, M., Miralles, A., & Esteban, S. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-23763-8.00031-2 · Cited by 1

Optical Monitoring of the Therapeutic Effects of Resveratrol on Neonatal Hypoxic-Ischemic Encephalopathy Using Diffuse Reflectance Spectroscopy

Maruyama, M., Nagamatsu, T., Kawauchi, S., Nishidate, I., & Sato, S. (2025) · Reproductive Sciences · doi:10.1007/s43032-025-01975-8

Sirtuins in neurodegenerative diseases

Sachan, N., Ali, Z., Fatma, N., & Chandra, P. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-45380-9.00002-x

Neuronal protection by sirtuins in Alzheimer's disease

Anekonda, T. S., & Reddy, P. H. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03492.x · Cited by 152

Targeting sirtuins in neurological disorders: A comprehensive review

Zhang, S.-Y., Yang, N., Hao, P.-H., Wen, R., & Zhang, T. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.139258 · Cited by 20

Sirtuins in Neuroendocrine Regulation and Neurological Diseases

Fujita, Y., & Yamashita, T. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00778 · Cited by 110

Sirtuins in neurodegenerative diseases: an update on potential mechanisms

Min, S., Sohn, P., Cho, S.-H., Swanson, R. A., & Gan, L. (2013) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2013.00053 · Cited by 124