Retinal stimulation strategies to restore vision: Fundamentals and systems

Retinitis pigmentosa

Hartong, D. T., Berson, E. L., & Dryja, T. P. (2006) · The Lancet · doi:10.1016/s0140-6736(06)69740-7 · Cited by 2,924

Prevalence of Age-Related Macular Degeneration in the United States

The Eye Diseases Prevalence Research Group* (2004) · Archives of Ophthalmology · doi:10.1001/archopht.122.4.564 · Cited by 2,774

Intravitreal aflibercept (VEGF trap-eye) in wet age-related macular degeneration

Heier, J. S., Brown, D. M., Chong, V., Korobelnik, J.-F., Kaiser, P. K., Nguyen, Q. D., Kirchhof, B., Ho, A., Ogura, Y., Yancopoulos, G. D., et al. (2012) · Ophthalmology · doi:10.1016/j.ophtha.2012.09.006 · Cited by 2,485

Independent optical excitation of distinct neural populations

Klapoetke, N. C., Murata, Y., Kim, S. S., Pulver, S. R., Birdsey-Benson, A., Cho, Y. K., Morimoto, T. K., Chuong, A. S., Carpenter, E. J., Tian, Z., et al. (2014) · Nature Methods · doi:10.1038/nmeth.2836 · Cited by 2,344

Neural Stimulation and Recording Electrodes

Cogan, S. F. (2008) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.10.061807.160518 · Cited by 2,243

Electrical stimulation of excitable tissue: design of efficacious and safe protocols

Merrill, D. R., Bikson, M., & Jefferys, J. G. R. (2005) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2004.10.020 · Cited by 2,078

Azobenzene photoswitches for biomolecules

Beharry, A. A., & Woolley, G. A. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15023e · Cited by 1,884

Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies

Schwartz, S. D., Regillo, C. D., Lam, B. L., Eliott, D., Rosenfeld, P. J., Gregori, N. Z., Hubschman, J.-P., Davis, J. L., Heilwell, G., Spirn, M., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(14)61376-3 · Cited by 1,327

The sensations produced by electrical stimulation of the visual cortex

Brindley, G. S., & Lewin, W. S. (1968) · The Journal of Physiology · doi:10.1113/jphysiol.1968.sp008519 · Cited by 1,170

Molecular and Cellular Approaches for Diversifying and Extending Optogenetics

Gradinaru, V., Zhang, F., Ramakrishnan, C., Mattis, J., Prakash, R., Diester, I., Goshen, I., Thompson, K. R., & Deisseroth, K. A. (2010) · Cell · doi:10.1016/j.cell.2010.02.037 · Cited by 1,040

Electrical, Electromagnetic, Ultrasound Wave Therapies, and Electronic Implants for Neuronal Rejuvenation, Neuroprotection, Axonal Regeneration, and IOP Reduction

Sharif, N. A. (2022) · Journal of Ocular Pharmacology and Therapeutics · doi:10.1089/jop.2022.0046 · Cited by 18

Lin28b stimulates the reprogramming of rat Müller glia to retinal progenitors

Zhao, C., Tao, Z., Xue, L., Zeng, Y., Wang, Y., Xu, H., & Yin, Z. Q. (2017) · Experimental Cell Research · doi:10.1016/j.yexcr.2017.02.010 · Cited by 16

A Systematic Review of Optogenetic Vision Restoration: History, Challenges, and New Inventions from Bench to BedsidePreprint

Stefanov, A., & Flannery, J. G. (2022) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a041304 · Cited by 16

Optogenetic restoration of high sensitivity vision with bReaChES, a red-shifted channelrhodopsin

Too, L. K., Shen, W., Protti, D. A., Sawatari, A., Black, D. A., Leamey, C. A., Huang, J. Y., Lee, S., Mathai, A. E., Lisowski, L., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-23572-4 · Cited by 15

Wireless and Opto-Stimulated Flexible Implants: Artificial Retina Constructed by Ferroelectric BiFeO3-BaTiO3/P(VDF-TrFE) Composites

Yuhong, Z., Liu, X., Ma, J., Wang, Z., Jiang, H., Sun, C., Jeong, D., Guan, H., & Chu, B. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c12460 · Cited by 15

Platinum Nanocrystal Assisted by Low‐Content Iridium for High‐Performance Flexible Electrode: Applications on Neural Interface, Water Oxidation, and Anti‐Microbial Contamination

Zeng, Q., Huang, Z., Cai, G., & Wu, T. (2021) · Advanced Materials Interfaces · doi:10.1002/admi.202100965 · Cited by 14

Bioinspired Structures and Design

Askarinejad, S., & Rahbar, N. (2020) · Cambridge University Press eBooks · doi:10.1017/9781139058995 · Cited by 15

Comparison of cortical responses to the activation of retina by visual stimulation and transcorneal electrical stimulation

Sun, P., Li, H., Lu, Z., Su, X., Ma, Z., Chen, J., Li, L., Zhou, C., Chen, Y., & Chai, X. (2018) · Brain stimulation · doi:10.1016/j.brs.2018.02.009 · Cited by 13

Electrostimulation in an autonomous culture lab-on-chip provides neuroprotection of a retinal explant from a retinitis pigmentosa mouse-model

Cabello, M., Mozo, M., de la Cerda, B., Aracil, C., Diaz-Corrales, F. J. J., Perdigones, F., Valdés-Sánchez, L., Relimpio, I., Bhattacharya, S. S., & Quero, J. M. (2019) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2019.02.118 · Cited by 13

Optogenetic Stimulation for Restoring Vision to Patients Suffering From Retinal Degenerative Diseases: Current Strategies and Future Directions

Montazeri, L., Zarif, N. E., Trenholm, S., & Sawan, M. (2019) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2019.2951298 · Cited by 13

Gene-independent therapeutic interventions to maintain and restore light sensitivity in degenerating photoreceptors

Žužić, M., Striebel, J., Pawlick, J. S., Sharma, K., Holz, F. G., & Busskamp, V. (2022) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2022.101065 · Cited by 12

Minimizing iridium oxide electrodes for high visual acuity subretinal stimulation

Damle, S., Carleton, M., Kapogianis, T., Arya, S., Cavichini-Corderio, M., Freeman, W. R., Lo, Y.-H., & Oesch, N. W. (2021) · eNeuro · doi:10.1523/eneuro.0506-20.2021 · Cited by 11

Cell-cell interaction in the pathogenesis of inherited retinal diseases

Du, X., Butler, A. G., & Chen, H. Y. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1332944 · Cited by 12

Electrical stimulation of different retinal components and the effect of asymmetric pulses

Raz-Prag, D., Beit-Yaakov, G., & Hanein, Y. (2017) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2017.07.028 · Cited by 11

An optimized content-aware image retargeting method: toward expanding the perceived visual field of the high-density retinal prosthesis recipients

Li, H., Zeng, Y., Lu, Z., Cao, X., Su, X., Sui, X., Wang, J., & Chai, X. (2017) · Journal of Neural Engineering · doi:10.1088/1741-2552/aa966d · Cited by 11

Cyclodextrin‐Assisted Delivery of Azobenzene Photoswitches for Uniform and Long‐Term Restoration of Light Responses in Degenerated Retinas of Blind Mice

Cao, K., Lyons, E. F., Smith, B. E., Denlinger, B. L., Ma, H., Shirian, J. D., & Krämer, R. (2021) · Advanced Therapeutics · doi:10.1002/adtp.202100127 · Cited by 13

Recognition of Moving Object in High Dynamic Scene for Visual Prosthesis

Guo, F., Yang, Y. W., Yang, X. I. A. O., Gao, Y. M., & Yu, N. (2019) · IEICE Transactions on Information and Systems · doi:10.1587/transinf.2018edp7405 · Cited by 11

Degeneration of retina-brain components and connections in glaucoma: Disease causation and treatment options for eyesight preservation

Sharif, N. A. (2022) · Current Research in Neurobiology · doi:10.1016/j.crneur.2022.100037 · Cited by 11

The role of the visual field size in artificial vision

Ghezzi, D. (2023) · Journal of Neural Engineering · doi:10.1088/1741-2552/acc7cd · Cited by 13

The visual cortical responses to sinusoidal transcorneal electrical stimulation

Su, X., Zhou, M., Di, L., Chen, J., Zhai, Z., Liang, J., Li, L., Li, H., & Chai, X. (2022) · Brain Research · doi:10.1016/j.brainres.2022.147875 · Cited by 11

Stimulus waveform design for decreasing charge and increasing stimulation selectivity in retinal prostheses

Kosta, P., Loizos, K., & Lazzi, G. (2020) · Healthcare Technology Letters · doi:10.1049/htl.2019.0115 · Cited by 13

Cell sheet engineering platforms integrating antibacterial and thermo-responsive functionalities: Cu-nanoparticle-loaded P4VP brushes for retinal cell sheet harvesting

Cieślik, A., Shymborska, Y., Tymetska, S., Stetsyshyn, Y., Bernasik, A., Brzychczy‐Włoch, M., Drożdż, K., Szajna, K., Krok, F., Budkowski, A., et al. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.162985 · Cited by 9

Ultrasound stimulation for non-invasive visual prostheses

Badadhe, J. D., Roh, H., Lee, B. C., Kim, J. H., & Im, M. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.971148 · Cited by 9

Bionic Vision Processing for Epiretinal Implant-Based Metaverse

Hu, H., Chen, C. P., Li, G., Jin, Z., Chu, Q., Han, B., & Zou, S. P. (2024) · ACS Applied Optical Materials · doi:10.1021/acsaom.3c00431 · Cited by 9

All-organic nanocomposite with strong photo-pyroelectric response and its application in retinal prosthesis

Wang, Z., Ma, J., Liu, J., Liu, X., Yuhong, Z., Guan, H., Sun, C., & Chu, B. (2024) · Nano Energy · doi:10.1016/j.nanoen.2024.110002 · Cited by 9

Prospects of Optogenetic Prosthesis of the Degenerative Retina of the Eye

Оstrovsky, М. А., & Kirpichnikov, M. P. (2019) · Biochemistry (Moscow) · doi:10.1134/s0006297919050031 · Cited by 9

Degenerated Cones in Cultured Human Retinas Can Successfully Be Optogenetically Reactivated

Kamar, S., Howlett, M. H. C., Klooster, J., de Graaff, W., Csikós, T., Rabelink, M. J. W. E., Hoeben, R. C., & Kamermans, M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21020522 · Cited by 9

Neuromodulation using electroosmosis

Kare, S. S., Rountree, C. M., Troy, J. B., Finan, J. D., & Saggere, L. (2021) · Journal of Neural Engineering · doi:10.1088/1741-2552/ac00d3 · Cited by 9

Electrical Stimulation Induced Current Distribution in Peripheral Nerves Varies Significantly with the Extent of Nerve Damage: A Computational Study Utilizing Convolutional Neural Network and Realistic Nerve Models

Du, J., Morales, A., Kosta, P., Bouteiller, J. C., Martı́nez, G., Warren, D. J., Fernández, E., & Lazzi, G. (2023) · International Journal of Neural Systems · doi:10.1142/s0129065723500223 · Cited by 9

Pre‐processing visual scenes for retinal prosthesis systems: A comprehensive review

Holiel, H. A., Fawzi, S. A., & Al‐Atabany, W. (2024) · Artificial Organs · doi:10.1111/aor.14824 · Cited by 11

Retinal prosthesis edge detection (RPED) algorithm: Low-power and improved visual acuity strategy for artificial retinal implants

Oh, Y., Hong, J., & Kim, J. (2024) · PLoS ONE · doi:10.1371/journal.pone.0305132 · Cited by 8

Suspended Silicon Microphotodiodes for Electrochemical and Biological Applications

Vargas‐Estevez, C., Duch, M., Duque, M., del Campo, F. J., Enríquez-Barreto, L., Murillo, G., Torras, N., Plaza, J. A., Saura, C. A., & Estéve, J. (2017) · Small · doi:10.1002/smll.201701920 · Cited by 8

Depth-Resolved Physiological Response of Retina to Transcorneal Electrical Stimulation Measured With Optical Coherence Tomography

Sun, P., Li, Q., Li, H., Di, L., Su, X., Chen, J., Zheng, H., Chen, Y., Zhou, C., & Chai, X. (2019) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2019.2912168 · Cited by 8

Advances in the Study of Age-Related Macular Degeneration Based on Cell or Cell-Biomaterial Scaffolds

Li, Z. M., Hu, Z., & Gao, Z. (2025) · Bioengineering · doi:10.3390/bioengineering12030278 · Cited by 7

Artificial vision: principles and prospects

Gilhooley, M. J., & Acheson, J. F. (2016) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000412 · Cited by 7

Contributions of Second- and Third-Order Retinal Neurons to Cone Electroretinograms After Loss of Rod Function in Rhodopsin P347L Transgenic Rabbits

Kominami, T., Ueno, S., Okado, S., Nakanishi, A., Kondo, M., & Terasaki, H. (2017) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.16-20344 · Cited by 7

Sensory augmentation to aid training with retinal prostheses

Kvansakul, J. G. S., Hamilton, L. H. W., Ayton, L. N., McCarthy, C. D., & Petoe, M. A. (2020) · Journal of Neural Engineering · doi:10.1088/1741-2552/ab9e1d · Cited by 7

Electrophysiological investigation of intact retina with soft printed organic neural interface

Vėbraitė, I., David‐Pur, M., Rand, D., Głowacki, E. D., & Hanein, Y. (2021) · Journal of Neural Engineering · doi:10.1088/1741-2552/ac36ab · Cited by 7

Optimizing the fabrication of a 3D high-resolution implant for neural stimulation

Shpun, G., Farah, N., Chemla, Y., Markus, A., Leibovitch, T. A., Lasnoy, E., Gerber, D., Zalevsky, Z., & Mandel, Y. (2023) · Journal of Biological Engineering · doi:10.1186/s13036-023-00370-8 · Cited by 7

Bamboo-Inspired Materials and Structures

Tan, T., & Soboyejo, W. O. (2020) · Cambridge University Press eBooks · doi:10.1017/9781139058995.005 · Cited by 7

Monitoring Cortical Response and Electrode-Retina Impedance Under Epiretinal Stimulation in Rats

Xie, H., Wang, Y., Ye, Z., Fang, S., Xu, Z., Wu, T., & Chan, L. L. H. (2021) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2021.3090904 · Cited by 8

Flying of Insects

Cheng, B. (2020) · Cambridge University Press eBooks · doi:10.1017/9781139058995.012 · Cited by 7

A three-dimensional bipolar microneedle electrode array with local ground integrated at each sidewall for enhanced focal electric stimulation

Chung, S.-H., Kim, C., Kim, M., Choi, D., Son, Y., Roh, H., Lee, B. C., Lee, H., Kim, Y., Lee, S.-K., et al. (2025) · Microsystems & Nanoengineering · doi:10.1038/s41378-025-01093-0 · Cited by 6

Integrated High-Temporal-Resolution and High-Density Subretinal Prosthesis Using a Correlated Double-Sampling Technique

Kang, H., Kim, J.-Y., & Kim, J. (2023) · Sensors · doi:10.3390/s23146501 · Cited by 6

Senior–Loken Syndrome: Ocular Perspectives on Genetics, Pathogenesis, and Management

Zhou, D., Zeng, Y., Luo, W., Leng, C., & Li, C. (2025) · Biomolecules · doi:10.3390/biom15050667 · Cited by 7

Performance improvement and in vivo demonstration of a sophisticated retinal stimulator using smart electrodes with built-in CMOS microchips

Noda, T., Nakano, Y., Terasawa, Y., Haruta, M., Sasagawa, K., Tokuda, T., & Ohta, J. (2018) · Japanese Journal of Applied Physics · doi:10.7567/jjap.57.1002b3 · Cited by 6

A hierarchical image processing strategy for artificial retinal prostheses

Jiang, H., Li, H., Liang, J., & Chai, X. (2020) · International Conference on Artificial Intelligence and Computer Engineering (ICAICE) · doi:10.1109/icaice51518.2020.00075 · Cited by 6

Cell-specific electrical stimulation of human retinal neurons assessed by pupillary response dynamics in vivo

Jung, R., Kelbsch, C., Wilhelm, H. M., Wilhelm, B., Straßer, T., Peters, T. M., Kempf, M., Kortüm, F. C., Pohl, L., Stingl, K. T., et al. (2022) · Experimental Eye Research · doi:10.1016/j.exer.2022.109185 · Cited by 6

Ambient Light Rejection Integrated Circuit for Autonomous Adaptation on a Sub-Retinal Prosthetic System

Kang, H., Choi, H., & Kim, J. (2021) · Sensors · doi:10.3390/s21165638 · Cited by 5

Differences in the spatial fidelity of evoked and spontaneous signals in the degenerating retina

Carleton, M., & Oesch, N. W. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.1040090 · Cited by 5

Decoding electroencephalographic responses to visual stimuli compatible with electrical stimulation

Romeni, S., Toni, L., Artoni, F., & Micera, S. (2024) · APL Bioengineering · doi:10.1063/5.0195680 · Cited by 5

Comparison of Monophasic and Biphasic Electrical Stimulation by Using Temporal Analysis for Different Inter-electrode Spacings in the Hexagonal Arrays

Çelik, M. E., & Karagoz, I. (2017) · Arabian Journal for Science and Engineering · doi:10.1007/s13369-017-2918-z · Cited by 5

Developmental Dynamics of the Functional State of the Retina in Mice with Inherited Photoreceptor Degeneration

Goriachenkov, A. A., Rotov, A. Y., & Firsov, M. L. (2021) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-021-01137-8 · Cited by 5

Machine Learning Method for Functional Assessment of Retinal Models

Papadopoulos, N., Melanitis, N., Lozano, A., Soto‐Sánchez, C., Fernández, E., & Nikita, K. S. (2021) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc46164.2021.9629599 · Cited by 5

The Effects of Phase Durations on the Spatial Responses of Retinal Ganglion Cells to Epi- and Sub-Retinal Electrical Stimulation

Tong, W., Stamp, M. E. M., Hejazi, M., Garrett, D. J., Prawer, S., & Ibbotson, M. R. (2019) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2019.8857347 · Cited by 5

Interfacing Neural Cells with Typical Microelectronics Materials for Future Manufacturing

Torres, F. P., Tokranova, N. A., Amodeo, E., Bertucci, T. B., Kiehl, T. R., Xie, Y., Cady, N. C., & Sharfstein, S. T. (2023) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2023.115749 · Cited by 4

Photovoltaic, wireless wide‐field epiretinal prosthesis to treat retinitis pigmentosa

Schulz, A., Knoll, T., Jaeger, T., Harzic, R. L., Stracke, F., Wien, S., Olsommer, Y., Meiser, I., Wagner, S., Rammensee, M., et al. (2024) · Acta Ophthalmologica · doi:10.1111/aos.16733 · Cited by 4

Cortical responses to prosthetic retinal stimulation are significantly affected by the light-adaptive state of the surrounding normal retina

Arens-Arad, T., Lender, R., Farah, N., & Mandel, Y. (2021) · Journal of Neural Engineering · doi:10.1088/1741-2552/abdd42 · Cited by 4

Integrated Low-Voltage Compliance and Wide-Dynamic Stimulator Design for Neural Implantable Devices

Oh, Y., Hong, J., & Kim, J. (2023) · Sensors · doi:10.3390/s23010492 · Cited by 4

Retinal Prostheses: The Argus System

Lin, T., Yue, L., & Humayun, M. S. (2017) · Technology & Innovation · doi:10.21300/19.3.2018.605 · Cited by 4

Clinical Observation and Genotype-Phenotype Analysis of ABCA4- Related Hereditary Retinal Degeneration before Gene Therapy

Zheng, H., Yuan, J., Xiao, X., Ye, L., & Chen, C. (2022) · Current Gene Therapy · doi:10.2174/1566523222666220216101539 · Cited by 4

Nature-inspired saccadic-like electrical stimulation paradigm promotes sustained retinal ganglion cell responses by spatiotemporally alternating activation of contiguous multi-electrode patterns

Haq, W., Basavaraju, S., Speck, A., & Zrenner, E. (2022) · Journal of Neural Engineering · doi:10.1088/1741-2552/ac8ad0 · Cited by 4

Artificial Vision: The High-Frequency Electrical Stimulation of the Blind Mouse Retina Decay Spike Generation and Electrogenically Clamped Intracellular Ca2+ at Elevated Levels

Peiroten, L., Zrenner, E., & Haq, W. (2023) · Bioengineering · doi:10.3390/bioengineering10101208 · Cited by 4

Initial Evaluation of the Safety and Durability of Retinal Prostheses Based on Suprachoroidal–transretinal Stimulation using Bullet-shaped Platinum Electrodes

Tashiro, H., Terasawa, Y., Kuwabara, M., Osawa, K., Tokuda, T., Ohta, J., & Fujikado, T. (2017) · Advanced Biomedical Engineering · doi:10.14326/abe.6.8 · Cited by 4

Stimulation strategies for selective activation of retinal ganglion cells

Chang, Y.-C., & Weiland, J. D. (2017) · International IEEE/EMBS Conference on Neural Engineering · doi:10.1109/ner.2017.8008361 · Cited by 4

An infrared image‐enhancement algorithm in simulated prosthetic vision: Enlarging working environment of future retinal prostheses

Liang, J., Li, H., Chen, J., Zhai, Z., Wang, J., Di, L., & Chai, X. (2022) · Artificial Organs · doi:10.1111/aor.14247 · Cited by 4

- Implantable Microdevices

Folch, A. (2016) · CRC Press eBooks · doi:10.1201/b12263-12 · Cited by 4

A novel simulation paradigm utilising MRI-derived phosphene maps for cortical prosthetic vision

Wang, H. Z., & Wong, Y. T. (2023) · Journal of Neural Engineering · doi:10.1088/1741-2552/aceca2 · Cited by 3

Photoreceptor‐Mimetic Microflowers for Restoring Light Responses in Degenerative Retina through a 2D Nanopetal/Cell Biointerface

Oudeng, G., Banerjee, S., Wang, Q., Jiang, D., Fan, Y., Wu, H., Pan, F., & Yang, M. (2024) · Small · doi:10.1002/smll.202400300 · Cited by 3

Sex-specific attenuation of photoreceptor degeneration by reserpine in a rhodopsin P23H rat model of autosomal dominant retinitis pigmentosaPreprint

Song, H. B., Campello, L., Mondal, A. K., Chen, H. Y., English, M. A., Glen, M., Vanlandingham, P. A., Farjo, R. A., & Swaroop, A. (2025) · eLife · doi:10.7554/elife.103888.3 · Cited by 6

Development of Chronic Implantable Electrodes for Long-term Visual Evoked Potential Recording in Rabbits

Kuwabara, M., Tashiro, H., Terasawa, Y., Osawa, K., Tokuda, T., Ohta, J., & Fujikado, T. (2017) · Advanced Biomedical Engineering · doi:10.14326/abe.6.59 · Cited by 3

Enhancing the Bionic Eye: A Real-time Image Optimization Framework to Encode Color and Spatial Information Into Retinal Prostheses

Huang, W. (2021) · IEEE MIT Undergraduate Research Technology Conference (URTC) · doi:10.1109/urtc54388.2021.9701618 · Cited by 3

Altered Regional Homogeneity in Patients With Congenital Blindness: A Resting-State Functional Magnetic Resonance Imaging Study

Hu, J.-J., Jiang, N., Chen, J., Ying, P., Kang, M., Xu, S., Zou, J., Wei, H., Ling, Q., & Shao, Y. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.925412 · Cited by 4

Electrical Stimulation Induced Current Distribution in Peripheral Nerves Varies Significantly with the Extent of Nerve Damage: A Computational Study Utilizing Convolutional Neural Network and Realistic Nerve Models

Du, J., Morales, A., Kosta, P., Bouteiller, J. C., Martínez, G., Warren, D. J., Fernández, E., & Lazzi, G. (2022) · Lecture notes in computer science · doi:10.1007/978-3-031-06242-1_52 · Cited by 3

Optogenetic approaches to gene therapy for vision restoration in retinal degenerative diseases

Mohanty, S. K., Idigo, C., Ayyagari, A. L., & Narcisse, D. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-819291-7.00004-6 · Cited by 3

A Retina-Inspired Computational Model for Stimulation Efficacy Characterization and Implementation Optimization of Implantable Optogenetic Epi-Retinal Neuro- Stimulators

Yousefi, T., & Kassiri, H. (2024) · IEEE Access · doi:10.1109/access.2024.3399711 · Cited by 3

Predicting Eye Fixations Using Computer Vision Techniques

Alevizaki, A., Melanitis, N., & Nikita, K. S. (2019) · IEEE International Conference on Bioinformatics and Bioengineering (BIBE) · doi:10.1109/bibe.2019.00062 · Cited by 3

Polypyrrole‐coated electrodes show thickness‐dependent stability in different conditions during 42‐day follow‐up in vitro

Alarautalahti, V., Hiltunen, M., Onnela, N., Nymark, S., Kellomäki, M., & Hyttinen, J. (2017) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.34024 · Cited by 3

A bionic eye: performance of the Argus II retinal prosthesis in low-vision and social rehabilitation of patients with end-stage retinitis pigmentosa

Тахчиди, Х. П., Kachalina, G. F., Тахчиди, Н. Х., Маноян, Р. А., & Глизница, П. В. (2019) · Bulletin of Russian State Medical University · doi:10.24075/brsmu.2019.042 · Cited by 3

A computational model to design wide field-of-view optic nerve neuroprostheses

Micera, S., Romeni, S., De Luca, D., Pierantoni, L., Toni, L., Marino, G., & Moccia, S. (2023) · doi:10.21203/rs.3.rs-3218482/v1 · Cited by 2

A computational model to design wide field-of-view optic nerve neuroprostheses

Romeni, S., Luca, D. D., Pierantoni, L., Toni, L., Marino, G., Moccia, S., & Micera, S. (2024) · iScience · doi:10.1016/j.isci.2024.111321 · Cited by 2

Australian research priorities for inherited retinal diseases: a James Lind Alliance priority setting partnership

Robertson, E. G., Hetherington, K., Prain, M., Ma, A. S., Ayton, L. N., Jamieson, R. V., Shepard, E., Boyd, L., Hall, J., Boyd, R., et al. (2025) · BMJ Open · doi:10.1136/bmjopen-2025-100301 · Cited by 2

Revisiting retinal and macular degeneration in the genomics era

Swaroop, A., & Roska, B. (2026) · Nature Reviews Genetics · doi:10.1038/s41576-026-00960-4 · Cited by 2

Aquatic Animals Operating at High Reynolds Numbers

Fish, F. E. (2020) · Cambridge University Press eBooks · doi:10.1017/9781139058995.011 · Cited by 2

Analysis of Electric Field Stimulation in Blue Light Stressed 661W Cells

Bola, S., Subramanian, P., Calzia, D., Dahl, A., Panfoli, I., Funk, R. H. W., & Roehlecke, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043433 · Cited by 2

Recent Advancements in Bioelectronic Medicine: A Review

Das, S., Ghosh, B., Sahoo, R. N., & Nayak, A. K. (2024) · Current Drug Delivery · doi:10.2174/0115672018286832231218112557 · Cited by 2

Toward Full‐Color Vision Restoration: Conjugated Polymers as Key Functional Materials in Artificial Retinal Prosthetics

Askew, L., Sweeney, A., Cox, D., & Shkunov, M. N. (2024) · Advanced Materials Interfaces · doi:10.1002/admi.202400128 · Cited by 4

A Highly-Scalable Poisson-Coded Retinal Optogenetic Stimulator With Fully-Analog ED-Based Adaptive Spike Detection and Closed-Loop Calibration

Yousefi, T., Zoidl, G., & Kassiri, H. (2024) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2024.3488713 · Cited by 4

Implantation of multiple suprachoroidal electrode arrays in rabbits

Abdallah, W., Li, W., Weiland, J. D., Humayun, M. S., & Ameri, H. (2017) · Journal of Current Ophthalmology · doi:10.1016/j.joco.2017.11.007 · Cited by 2

Investigation of Surgical Techniques for Optimization of Long-Term Outcomes of LCP-Based Retinal Prosthesis Implantation

Bae, S. H., Jeong, J., Kim, S. J., Chung, H., & Seo, J.-M. (2018) · Translational Vision Science & Technology · doi:10.1167/tvst.7.4.17 · Cited by 2

Virus Vectors for Optogenetic Prosthetization of the Retina

Rotov, A. Y., Nikolaeva, D. A., Astakhova, L. A., & Firsov, M. L. (2020) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-020-00911-4 · Cited by 2

A scalable data transmission scheme for implantable optogenetic visual prostheses

Hou, Z., Al‐Atabany, W., Farag, R., Vuong, Q. C., Mokhov, A., & Degenaar, P. A. (2020) · Journal of Neural Engineering · doi:10.1088/1741-2552/abaf2e · Cited by 2

PDE6B Mutation-associated Inherited Retinal Disease

Marconi, S., & Stout, J. T. (2021) · International Ophthalmology Clinics · doi:10.1097/iio.0000000000000367 · Cited by 2

Retinal Prostheses: Bioengineering Considerations

Chang, Y.-C., Weiland, J. D., & Humayun, M. S. (2017) · Essentials in ophthalmology/Essentials ophthalmology · doi:10.1007/978-3-319-67260-1_2 · Cited by 2

A preliminary implementation of an active intraocular prosthesis as a new image acquisition device for a cortical visual prosthesis

Shim, S., Seo, K., & Kim, S. J. (2020) · Journal of Artificial Organs · doi:10.1007/s10047-020-01168-x · Cited by 2

A facile and comprehensive algorithm for electrical response identification in mouse retinal ganglion cells

Li, W., Qin, S., Lu, Y., Wang, H., Xu, Z., & Wu, T. (2021) · PLoS ONE · doi:10.1371/journal.pone.0246547 · Cited by 2

1V 4.49nW/Pixel Retinal Prosthesis Chip with Light-to-Stimulus Duration Converter

Choi, D.-H., & Jee, D. (2021) · IEEE International Symposium on Circuits and Systems proceedings · doi:10.1109/iscas51556.2021.9401380 · Cited by 2

Towards the Next Generation of Retinal Neuroprosthesis: Visual Computation with SpikesPreprint

Yu, Z., Liu, J. K., Jia, S., Zhang, Y., Zheng, Y., Tian, Y., & Huang, T. (2020) · arXiv (Cornell University) · doi:10.48550/arxiv.2001.04064 · Cited by 2

Biomimetic graphitic carbon nitride nanoparticles enable multiscale biomodulationPreprint

Müller, C., Klompmaker, K. K., Zhang, Y., Zhang, J., Kalatanova, A. V., Li, P., Meng, L., Madsen, J. G., Jakobsen, T. S., Jørgensen, A. C., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.23.619813 · Cited by 2

Improving Spatial Resolution and Selectivity of Transcorneal Electrical Stimulation by Temporal Interference Technology

Ma, S., Song, X., Guo, T., Zhou, F., Liu, Z., Chai, X., & Li, L. (2023) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc40787.2023.10341049 · Cited by 1

Optical and Electronic Approaches to Restoration of Sight to the Blind

Palanker, D. (2015) · Imaging and Applied Optics · doi:10.1364/isa.2015.im3a.2

Optogenetic Stimulation for Restoring Vision to Patients Suffering From Retinal Degenerative Diseases: Current Strategies and Future Directions

Montazeri, L., Zarif, N. E., Trenholm, S., & Sawan, M. (2019) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2019.2951298 · Cited by 13

Electrical stimulation of degenerate retina

Chan, L. H. L. (2015) · University of Southern California Digital Library · doi:10.25549/usctheses-m2420

The Retina Implant New Approach to a Visual Prosthesis / Das Retina-Implant Ein neuer Ansatz für eine Sehprothese

Alteheld, N., Roessler, G. F., Vobig, M. A., & Walter, P. (2004) · Biomedizinische Technik/Biomedical Engineering · doi:10.1515/bmt.2004.020 · Cited by 19

Electronic Approaches to Restitute Vision in Patients with Neurodegenerative Diseases of the Retina

Štingl, K., & Zrenner, E. (2013) · Ophthalmic Research · doi:10.1159/000354424 · Cited by 27