Pharmacotherapy of Obsessive-compulsive Disorder and Obsessive-Compulsive Spectrum Disorders
Abstract
This article reviews new developments of pharmacotherapy in obsessive-compulsive disorder (OCD) and OC spectrum disorders of the past five years. New developments primarily involved the ex-tension of evidence of efficacy of serotonin reuptake inhibitors(SRIs), the use of atypical antipsychotics in addition to SRIs for treatment refractory patients, the combination of pharmacotherapy with behavior therapy, and studies assessing predictors of response. Today, frontline pharmacological treatment of OCD still consists of drugs with potent serotonin reuptake inhibition proper-ties. In case of non-response, treatment options comprise adding another drug, increasing the dose, switching drugs, or changing the mode of delivery.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Obsessive-compulsive disorder is characterized by recurrent unwanted thoughts, anxiety and compulsive behavior, and is often associated with cognitive deficits.
“Obsessive‐compulsive disorder (OCD) is a psychiatric disorder that is characterized by recurrent unwanted thoughts, anxiety and compulsive behavior, but is also often associated with cognitive deficits.1, 2, 3, 4, 5”
From Behavioral flexibility in a mouse model for obsessive‐compulsive disorder: Impaired Pavlovian reversal learning in SAPAP3 mutants (2019) · cites this paper as [2]
Cites
The Yale-Brown Obsessive Compulsive Scale: I. Development, Use, and Reliability
Goodman, W. K. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810110048007 · Cited by 7,712 · see citing works
J Neuropsychiatry Clin Neurosci
Yudofsky, S. C., & Hales, R. E. (1992) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/jnp.4.4.359 · Cited by 3,818 · see citing works
The Yale-Brown Obsessive Compulsive Scale: II. Validity
Goodman, W. K. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810110054008 · Cited by 2,799 · see citing works
The Yale-Brown Obsessive-Compulsive Scale: Measures of internal consistency
Kim, S. W., Dysken, M. W., Pheley, A. M., & Hoover, K. M. (1994) · Psychiatry Research · doi:10.1016/0165-1781(94)90039-6 · Cited by 2,361 · see citing works
Foa, E. B., Liebowitz, M. R., Kozak, M. J., Davies, S., Campeas, R., Franklin, M. E., Huppert, J. D., Kjernisted, K., Rowan, V., Schmidt, A. B., et al. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.1.151 · Cited by 1,048 · see citing works
Mataix-Cols, D., Rauch, S. L., Manzo, P. A., Jenike, M. A., & Baer, L. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.9.1409 · Cited by 716 · see citing works
Siegel, R. S., & WEIDEN, I. (1968) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/00005373-196811000-00016 · Cited by 671 · see citing works
Compulsive buying: a report of 20 cases.
McElroy, S. L., Keck, P. E., Pope, H. G., Smith, J., & Strakowski, S. M. (1994) · PubMed · Cited by 646 · see citing works
McDougle, C. J., Epperson, C. N., Pelton, G. H., Wasylink, S., & Price, L. H. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.8.794 · Cited by 571 · see citing works
Eddy, K. T., Dutra, L., Bradley, R., & Westen, D. (2004) · Clinical Psychology Review · doi:10.1016/j.cpr.2004.08.004 · Cited by 475 · see citing works
Treatment non-response in OCD: methodological issues and operational definitions
Pallanti, S., Hollander, E., Bienstock, C., Koran, L., Leckman, J., Marazziti, D., Pato, M., Stein, D., Zohar, J., & International Treatment Refractory OCD Consortium (2002) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145702002900 · Cited by 416 · see citing works
Saxena, S. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00082-2 · Cited by 379 · see citing works
ROSENBERG, D. R., MacMASTER, F. P., KESHAVAN, M. S., FITZGERALD, K. D., STEWART, C. M., & MOORE, G. J. (2000) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200009000-00008 · Cited by 377 · see citing works
Evidence-based pharmacotherapy of obsessive-compulsive disorder
Fineberg, N. A., Brown, A., Reghunandanan, S., & Pampaloni, I. (2012) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145711001829 · Cited by 336 · see citing works
(1996) · PubMed · Cited by 310 · see citing works
Paroxetine versus Clomipramine in the Treatment of Obsessive–Compulsive Disorder
Zohar, J., Judge, R., & Ocd Paroxetine Study Investigators (1996) · The British Journal of Psychiatry · doi:10.1192/bjp.169.4.468 · Cited by 272 · see citing works
Alonso, P., Menchón, J. M., Pifarré, J., Mataix‐Cols, D., Torres, L., Salgado, P., & Vallejo, J. (2001) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v62n07a06 · Cited by 254 · see citing works
Denys, D., de Geus, F., van Megen, H. J. G. M., & Westenberg, H. G. M. (2004) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v65n0803 · Cited by 248 · see citing works
Self-citationHigh-Dose Sertraline Strategy for Nonresponders to Acute Treatment for Obsessive-Compulsive Disorder
Ninan, P. T., Koran, L. M., Kiev, A., Davidson, J. R. T., Rasmussen, S. A., Zajecka, J., Robinson, D. G., Crits-Christoph, P. F., Mandel, F. S., & Austin, C. (2006) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v67n0103 · Cited by 246 · see citing works
Bystritsky, A., Ackerman, D. L., Rosen, R. M., Vapnik, T., Gorbis, E., Maidment, K. M., & Saxena, S. (2004) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v65n0418 · Cited by 220 · see citing works
Foa, E. B., Franklin, M. E., & Moser, J. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01552-4 · Cited by 219 · see citing works
Evidence-based pharmacotherapy of obsessive–compulsive disorder
Fineberg, N. A., & Gale, T. M. (2005) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145704004675 · Cited by 213 · see citing works
Saxena, S., Brody, A. L., Ho, M. L., Zohrabi, N., Maidment, K. M., & Baxter, L. R. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.3.522 · Cited by 210 · see citing works
Fluoxetine treatment of nonparaphilic sexual addictions and paraphilias in men.
Kafka, M. P., & PRENTKY, R. A. (1992) · PubMed · Cited by 209 · see citing works
Neurobiology of the obsessive–compulsive spectrum disorders
Stein, D. J. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00271-1 · Cited by 204 · see citing works
Multivariate Meta-Analysis of Controlled Drug Studies for Obsessive-Compulsive Disorder
Ackerman, D. L., & Greenland, S. (2002) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-200206000-00012 · Cited by 202 · see citing works
Saxena, S., Brody, A. L., Ho, M. L., Alborzian, S., Maidment, K. M., Zohrabi, N., Ho, M. K., Huang, S., Wu, H.-M., & Baxter, L. R. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.3.250 · Cited by 201 · see citing works
McDougle, C. J., Epperson, C. N., Price, L. H., & Gelernter, J. E. (1998) · Molecular Psychiatry · doi:10.1038/sj.mp.4000391 · Cited by 200 · see citing works
Hollander, E., Rossi, N. B., Sood, E., & Pallanti, S. (2003) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145703003730 · Cited by 197 · see citing works
Kishore, V. R., Samar, R., Reddy, Y. C. J., Chandrasekhar, C. R., & Thennarasu, K. (2004) · European Psychiatry · doi:10.1016/j.eurpsy.2003.12.005 · Cited by 192 · see citing works
Serotonergic medications for sexual obsessions, sexual addictions, and paraphilias.
Stein, D. J., Hollander, E., Anthony, D. T., Schneier, F. R., Fallon, B. A., Liebowitz, M. R., & Klein, D. F. (1992) · PubMed · Cited by 189 · see citing works
A Double-Blind Trial of Fluoxetine in Pathologic Skin Picking
Simeon, D., Stein, D. J., Gross, S., Islam, N., Schmeidler, J., & Hollander, E. (1997) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v58n0802 · Cited by 186 · see citing works
Montgomery, S., Kasper, S. F., Stein, D. J., Hedegaard, K. B., & Lemming, O. M. (2001) · International Clinical Psychopharmacology · doi:10.1097/00004850-200103000-00002 · Cited by 184 · see citing works
Sertraline Pharmacotherapy for Paraphilias and Paraphilia-Related Disorders: An Open Trial
Kafka, M. P. (1994) · Annals of Clinical Psychiatry · doi:10.3109/10401239409149003 · Cited by 179 · see citing works
Rauch, S. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(02)00351-2 · Cited by 173 · see citing works
Placebo-Controlled Study of Fluvoxamine in the Treatment of Patients With Compulsive Buying
Ninan, P. T., McElroy, S. L., Kane, C. P., Knight, B. T., Casuto, L., Rose, S. E., Marsteller, F., & Nemeroff, C. B. (2000) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-200006000-00012 · Cited by 172 · see citing works
Montgomery, S. A. (1993) · European Neuropsychopharmacology · doi:10.1016/0924-977x(93)90266-o · Cited by 172 · see citing works
Post-treatment effects of exposure therapy and clomipramine in obsessive–compulsive disorder
Simpson, H. B., Liebowitz, M. R., Foa, E. B., Kozak, M. J., Schmidt, A. B., Rowan, V., Petkova, E., Kjernisted, K., Huppert, J. D., Franklin, M. E., et al. (2004) · Depression and Anxiety · doi:10.1002/da.20003 · Cited by 161 · see citing works
Hollander, E., Allen, A., Steiner, M., Wheadon, D. E., Oakes, R., Burnham, D. B., & Paroxetine OCD Study Group (2003) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v64n0919 · Cited by 156 · see citing works
Obsessive compulsive spectrum disorders.
Rasmussen, S. A. (1994) · PubMed · Cited by 156 · see citing works
Black, D. W., Gabel, J., Hansen, J., & Schlosser, S. (2000) · Annals of Clinical Psychiatry · doi:10.3109/10401230009147113 · Cited by 156 · see citing works
Shapira, N. A., Ward, H. E., MANDOKI, M. W., Murphy, T. K., Yang, M. C. K., Blier, P., & Goodman, W. K. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.11.010 · Cited by 155 · see citing works
Fluvoxamine in the Treatment of Compulsive Buying
Black, D. W., Monahan, P. O., & Gabel, J. (1997) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v58n0404 · Cited by 152 · see citing works
A Double Blind Comparison of Venlafaxine and Paroxetine in Obsessive-Compulsive Disorder
Denys, D., van der Wee, N., van Megen, H. J. G. M., & Westenberg, H. G. M. (2003) · Journal of Clinical Psychopharmacology · doi:10.1097/01.jcp.0000095342.32154.54 · Cited by 151 · see citing works
Self-citationAtmaca, M., Kuloğlu, M. M., Tezcan, E., & Geçici, Ö. (2002) · International Clinical Psychopharmacology · doi:10.1097/00004850-200205000-00004 · Cited by 149 · see citing works
Defining Response in Clinical Trials for Obsessive-Compulsive Disorder
Tolin, D. F., Abramowitz, J. S., & Diefenbach, G. J. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n1209 · Cited by 148 · see citing works
Leonard, H. L. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810330045007 · Cited by 146 · see citing works
A Double-Blind Switch Study of Paroxetine and Venlafaxine in Obsessive-Compulsive Disorder
Denys, D. A. J. P., van Megen, H. J. G. M., van der Wee, N. J. A., & Westenberg, H. G. M. (2004) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v65n0106 · Cited by 144 · see citing works
Self-citationWCA Recommendations for the Long-Term Treatment of Obsessive-Compulsive Disorder in Adults
Greist, J. H., Bandelow, B., Hollander, E., Marazziti, D., Montgomery, S., Nutt, D., Okasha, A., Swinson, R. P., & Zohar, J. (2003) · CNS Spectrums · doi:10.1017/s1092852900006908 · Cited by 143 · see citing works
Billett, E. A., Richter, M. A., King, N. A., Heils, A., Lesch, K., & Kennedy, J. L. (1997) · Molecular Psychiatry · doi:10.1038/sj.mp.4000257 · Cited by 143 · see citing works
Efficacy of Sertraline in the Long-Term Treatment of Obsessive-Compulsive Disorder
Koran, L. M., Hackett, E., Rubin, A., Wolkow, R., & Robinson, D. G. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.1.88 · Cited by 140 · see citing works
Obsessive-Compulsive Disorders: Practical Management
Jenike, M. A., Baer, L., & Minichiello, W. E. (1998) · Cited by 136 · see citing works
Erzegovesi, S., Guglielmo, E., Siliprandi, F., & Bellodi, L. (2004) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2004.04.004 · Cited by 136 · see citing works
The Use of Aripiprazole in Obsessive-Compulsive Disorder
Connor, K. M., Payne, V., Gadde, K. M., Zhang, W., & Davidson, J. R. T. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0107 · Cited by 135 · see citing works
Greist, J. H., Jefferson, J. W., Kobak, K. A., Chouinard, G., DuBoff, E., Halaris, A., Kim, S. W., Koran, L. M., Liebowtiz, M. R., Lydiard, B., et al. (1995) · International Clinical Psychopharmacology · doi:10.1097/00004850-199506000-00001 · Cited by 133 · see citing works
Carey, P. D., Vythilingum, B., Seedat, S., Muller, J. E., van Ameringen, M., & Stein, D. J. (2005) · BMC Psychiatry · doi:10.1186/1471-244x-5-5 · Cited by 133 · see citing works
Double-Blind Treatment With Oral Morphine in Treatment-Resistant Obsessive-Compulsive Disorder
Koran, L. M., Aboujaoude, E. N., Bullock, K. D., Franz, B., Gamel, N. N., & Elliott, M. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0312 · Cited by 132 · see citing works
Citalopram Treatment of Compulsive Shopping
Koran, L. M., Bullock, K. D., Hartston, H. J., Elliott, M. A., & D'Andrea, V. J. (2002) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v63n0808 · Cited by 131 · see citing works
Hoehn‐Saric, R., Ninan, P. T., Black, D. W., Stahl, S. M., Greist, J. H., Lydiard, B., McElroy, S. L., Zajecka, J., Chapman, D. S., Clary, C. M., et al. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.1.76 · Cited by 127 · see citing works
Ameringen, M. V., Mancini, C., Patterson, B. A., & Bennett, M. (2005) · Depression and Anxiety · doi:10.1002/da.20118 · Cited by 124 · see citing works
Neziroglu, F., Stevens, K. P., McKay, D., & Yaryura-Tobias, J. A. (2001) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(00)00053-x · Cited by 122 · see citing works
Refractory obsessive-compulsive disorder: state-of-the-art treatment.
Hollander, E., Bienstock, C. A., Koran, L. M., Pallanti, S., Marazziti, D., Rasmussen, S. A., Ravizza, L., Benkelfat, C., Saxena, S., Greenberg, B. D., et al. (2002) · PubMed · Cited by 119 · see citing works
Coric, V., Milanovic, S. M., Wasylink, S., Patel, P., Malison, R. T., & Krystal, J. H. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1396-z · Cited by 118 · see citing works
Pallanti, S., Quercioli, L., & Bruscoli, M. (2004) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v65n1015 · Cited by 118 · see citing works
Dannon, P. N., Sasson, Y., Hirschmann, S., Iancu, I., Grunhaus, L. J., & Zohar, J. (2000) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(00)00065-1 · Cited by 116 · see citing works
Fluoxetine in Pathologic Skin-Picking: Open-Label and Double-Blind Results
Bloch, M. R., Elliott, M., THOMPSON, H. B., & Koran, L. M. (2001) · Psychosomatics · doi:10.1176/appi.psy.42.4.314 · Cited by 111 · see citing works
Fallon, B. A., Liebowitz, M. R., Campeas, R. B., Schneier, F. R., Marshall, R. D., Davies, S. O., Goetz, D. M., & Klein, D. F. (1998) · PubMed · doi:10.1001/archpsyc.55.10.918 · Cited by 111 · see citing works
Li, X., May, R. S., Tolbert, L. C., Jackson, W. T., Flournoy, J. M., & Baxter, L. R. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0610 · Cited by 110 · see citing works
Neurotic excoriations: A review and some new perspectives
Gupta, M. A., Gupta, A. K., & Haberman, H. F. (1986) · Comprehensive Psychiatry · doi:10.1016/0010-440x(86)90014-3 · Cited by 110 · see citing works
A Review of Pharmacologic Treatments for Obsessive-Compulsive Disorder
Kaplan, A., & Hollander, E. (2003) · Psychiatric Services · doi:10.1176/appi.ps.54.8.1111 · Cited by 108 · see citing works
Rufer, M., Hand, I., Alsleben, H., Braatz, A., Ortmann, J., Katenkamp, B., Fricke, S., & Peter, H. (2004) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-004-0544-8 · Cited by 107 · see citing works
Fineberg, N. A., Sivakumaran, T., Roberts, A., & Gale, T. (2005) · International Clinical Psychopharmacology · doi:10.1097/00004850-200507000-00005 · Cited by 105 · see citing works
Hollander, E., Koran, L. M., Goodman, W. K., Greist, J. H., Ninan, P. T., Yang, H., Li, D., & Barbato, L. M. (2003) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v64n0604 · Cited by 103 · see citing works
Rapid benefit of intravenous pulse loading of clomipramine in obsessive- compulsive disorder
Koran, L. M., Sallee, F. R., & Pallanti, S. (1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.3.396 · Cited by 102 · see citing works
Nakatani, E., Nakagawa, A., Nakao, T., Yoshizato, C., Nabeyama, M., Kudo, A., Isomura, K., Kato, N., Yoshioka, K., & Kawamoto, M. (2005) · Psychotherapy and Psychosomatics · doi:10.1159/000086317 · Cited by 102 · see citing works
Romano, S. J., Goodman, W. K., Tamura, R., & Gonzales, J. S. (2001) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-200102000-00009 · Cited by 98 · see citing works
van Oppen, P., van Balkom, A. J. L. M., de Haan, E., & van Dyck, R. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n1111 · Cited by 97 · see citing works
An Open Clinical Trial of Fluvoxamine Treatment of Psychogenic Excoriation
Arnold, L. M., Mutasim, D. F., Dwight, M. M., Lamerson, C. L., Morris, E. M., & McElroy, S. L. (1999) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199902000-00005 · Cited by 97 · see citing works
A double-blind, placebo-controlled trial of clonazepam in obsessive–compulsive disorder
Hollander, E., Kaplan, A., & Stahl, S. M. (2003) · The World Journal of Biological Psychiatry · doi:10.3109/15622970309167908 · Cited by 97 · see citing works
A placebo-controlled cross-over trial of adjunctive EPA in OCD
Fux, M., Benjamin, J., & Nemets, B. (2004) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(03)00077-3 · Cited by 95 · see citing works
Venlafaxine Versus Clomipramine in the Treatment of Obsessive-Compulsive Disorder
Albert, U., Aguglia, E., Maina, G., & Bogetto, F. (2002) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v63n1108 · Cited by 93 · see citing works
Kampman, M., Keijsers, G. P. J., Hoogduin, C. A. L., & Verbraak, M. J. P. M. (2002) · Acta Psychiatrica Scandinavica · doi:10.1034/j.1600-0447.2002.01261.x · Cited by 93 · see citing works
An Open-Label Trial of St. John's Wort (Hypericum perforatum) in Obsessive-Compulsive Disorder
Taylor, L., & Kobak, K. A. (2000) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v61n0806 · Cited by 92 · see citing works
Koran, L. M., Gamel, N. N., Choung, H. W., Smith, E. H., & Aboujaoude, E. N. (2005) · PubMed · Cited by 91 · see citing works
Nefazodone and the treatment of nonparaphilic compulsive sexual behavior: a retrospective study.
Coleman, E., Gratzer, T. G., Nesvacil, L. J., & Raymond, N. C. (2000) · PubMed · Cited by 83 · see citing works
Mirtazapine for Obsessive-Compulsive Disorder
Koran, L. M., Gamel, N. N., Choung, H. W., Smith, E. H., & Aboujaoude, E. N. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0415 · Cited by 83 · see citing works
Do antipsychotics ameliorate or exacerbate Obsessive Compulsive Disorder symptoms?
Sareen, J., Kirshner, A., Lander, M., Kjernisted, K. D., Eleff, M. K., & Reiss, J. P. (2004) · Journal of Affective Disorders · doi:10.1016/j.jad.2004.03.011 · Cited by 79 · see citing works
Citalopram intravenous infusion in resistant obsessive-compulsive disorder: an open trial.
Pallanti, S., Quercioli, L., & Koran, L. M. (2002) · PubMed · Cited by 73 · see citing works
Obsessive-Compulsive Disorder, 5-HTTLPR polymorphism and treatment response
Bella, D. D., Erzegovesi, S., Cavallini, M. C., & Bellodi, L. (2002) · The Pharmacogenomics Journal · doi:10.1038/sj.tpj.6500090 · Cited by 73 · see citing works
A Double-Blind Combination Study of Clonazepam with Sertraline in Obsessive-Compulsive Disorder
Crockett, B. A., Churchill, E., & Davidson, J. R. T. (2004) · Annals of Clinical Psychiatry · doi:10.1080/10401230490486972 · Cited by 72 · see citing works
Tenneij, N. H., van Megen, H. J. G. M., Denys, D. A. J. P., & Westenberg, H. G. M. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0913 · Cited by 71 · see citing works
Self-citationPredictors of response to pharmacotherapy with citalopram in obsessive-compulsive disorder
Stein, D. J., Montgomery, S., Kasper, S. F., & Tanghøj, P. (2001) · International Clinical Psychopharmacology · doi:10.1097/00004850-200111000-00007 · Cited by 70 · see citing works
Amisulpiride augmentation in treatment resistant obsessive–compulsive disorder: an open trial
Metin, Ö., Yazıcı, K., Tot, Ş., & Yazıcı, A. (2003) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.512 · Cited by 68 · see citing works
A score for predicting response to pharmacotherapy in obsessive???compulsive disorder
Denys, D., Burger, H., van Megen, H., de Geus, F., & Westenberg, H. (2003) · International Clinical Psychopharmacology · doi:10.1097/00004850-200311000-00002 · Cited by 68 · see citing works
Self-citationMundo, E., Rouillon, F., Figueira, M. L., & Stigler, M. (2001) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.317 · Cited by 66 · see citing works
Venlafaxine in Treatment-Resistant Obsessive-Compulsive Disorder
Hollander, E., Friedberg, J. P., Wasserman, S., Allen, A., Birnbaum, M., & Koran, L. M. (2003) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v64n0508 · Cited by 66 · see citing works
Pilot Trial of Ondansetron in the Treatment of 8 Patients With Obsessive-Compulsive Disorder
Hewlett, W. A., Schmid, S. P., & Salomon, R. M. (2003) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v64n0907 · Cited by 66 · see citing works
Fenfluramine in Prader-Willi syndrome: a double blind, placebo controlled trial.
Selikowitz, M., Sunman, J., Pendergast, A., & Wright, S. (1990) · Archives of Disease in Childhood · doi:10.1136/adc.65.1.112 · Cited by 63 · see citing works
Bergeron, R., Ravindran, A. V., Chaput, Y., Goldner, E. M., Swinson, R. P., Ameringen, M. A. V., Austin, C., & Hadrava, V. (2002) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-200204000-00007 · Cited by 62 · see citing works
Citalopram Treatment of Compulsive Shopping
Pallanti, S., Quercioli, L., & Koran, L. M. (2002) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v63n0908 · Cited by 62 · see citing works
Maina, G., Albert, U., Ziero, S., & Bogetto, F. (2003) · International Clinical Psychopharmacology · doi:10.1097/01.yic.0000047784.24295.2b · Cited by 61 · see citing works
Effect of adjuvant pindolol on the antiobsessional response to fluvoxamine
Mundo, E., Guglielmo, E., & Bellodi, L. (1998) · International Clinical Psychopharmacology · doi:10.1097/00004850-199809000-00005 · Cited by 59 · see citing works
Lamotrigine Augmentation of Serotonin Re-Uptake Inhibitors in Obsessive–Compulsive Disorder
Kumar, T. C. R., & Khanna, S. (2000) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/j.1440-1614.2000.0751c.x · Cited by 59 · see citing works
Pharmacologic treatment of severe skin-picking behaviors in Prader-Willi syndrome. Two case reports
Warnock, J. K. (1992) · Archives of Dermatology · doi:10.1001/archderm.128.12.1623 · Cited by 57 · see citing works
Are fluoxetine plasma levels related to outcome in obsessive-compulsive disorder?
Koran, L. M., Jw, C., Ra, D., Rush, A. J., & Thiemann, S. (1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.11.1450 · Cited by 56 · see citing works
Hoehn‐Saric, R., Schlaepfer, T. E., Greenberg, B. D., McLeod, D. R., Pearlson, G. D., & Wong, S. H. (2001) · Psychiatry Research Neuroimaging · doi:10.1016/s0925-4927(01)00114-7 · Cited by 56 · see citing works
Inositol in the Treatment of Trichotillomania and Compulsive Skin Picking
Seedat, S., Stein, D. J., & Harvey, B. H. (2001) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v62n0112f · Cited by 56 · see citing works
Venlafaxine in Obsessive-compulsive Disorder
Yaryura-Tobias, J. A. (1996) · Archives of General Psychiatry · doi:10.1001/archpsyc.1996.01830070103016 · Cited by 53 · see citing works
Hembree, E. A., Riggs, D. S., Kozak, M. J., Franklin, M. E., & Foa, E. B. (2003) · CNS Spectrums · doi:10.1017/s1092852900018629 · Cited by 48 · see citing works
Kindler, S., Dannon, P. N., Iancu, I., Sasson, Y., & Zohar, J. (1997) · Clinical Neuropharmacology · doi:10.1097/00002826-199704000-00003 · Cited by 47 · see citing works
Quantitative Electroencephalography in OCD Patients Treated with Paroxetine
Hansen, E. S., Prichep, L. S., Bolwig, T. G., & John, E. R. (2003) · Clinical Electroencephalography · doi:10.1177/155005940303400205 · Cited by 47 · see citing works
Antipsychotic Treatment in Obsessive Compulsive Disorder: A Literature Review
Keuneman, R. J., Pokos, V., Weerasundera, R., & Castle, D. J. (2005) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/j.1440-1614.2005.01591.x · Cited by 46 · see citing works
Bupropion for Patients With Obsessive-Compulsive Disorder
Vulink, N. C. C., Denys, D. A. J. P., & Westenberg, H. G. M. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0211 · Cited by 46 · see citing works
Self-citationPHARMACOTHERAPY FOR OBSESSIVE-COMPULSIVE DISORDER
Hollander, E., Kaplan, A., Allen, A., & Cartwright, C. (2000) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(05)70186-6 · Cited by 45 · see citing works
Nicotine treatment of obsessive–compulsive disorder
Lundberg, S., Carlsson, A., Norfeldt, P., & Carlsson, M. L. (2004) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2004.06.014 · Cited by 40 · see citing works
(1997) · PubMed · Cited by 40 · see citing works
Platelet Serotonergic Markers as Endophenotypes for Obsessive-Compulsive Disorder
Delorme, R., Betancur, C., Callebert, J., Chabane, N., Laplanche, J., Mouren, M., Launay, J., & Leboyer, M. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300752 · Cited by 37 · see citing works
Kamijima, K., Murasaki, M., Asai, M., Higuchi, T., Nakajima, T., Taga, C., & Matsunaga, H. (2004) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2004.01278.x · Cited by 35 · see citing works
Effects of Donepezil on Compulsive Hypersexual Behavior in Parkinson Disease
Ivanco, L. S., & Bohnen, N. I. (2005) · American Journal of Therapeutics · doi:10.1097/01.mjt.0000151861.59698.26 · Cited by 34 · see citing works
Citalopram in refractory obsessive-compulsive disorder: an open study
Marazziti, D., Dell’Osso, L., Gemignani, A., Ciapparelli, A., Presta, S., Nasso, E. D., Pfanner, C., & Cassano, G. B. (2001) · International Clinical Psychopharmacology · doi:10.1097/00004850-200107000-00005 · Cited by 33 · see citing works
Obsessive-Compulsive Spectrum Disorders: Effective Treatment with Paroxetine
Ravindran, A. V., Lapierre, Y. D., & Anisman, H. (1999) · The Canadian Journal of Psychiatry · doi:10.1177/070674379904400808 · Cited by 32 · see citing works
Psychopharmacology of compulsive buying
Bullock, K. D., & Koran, L. (2003) · Drugs of today · doi:10.1358/dot.2003.39.9.799477 · Cited by 31 · see citing works
The adequacy of pharmacotherapy in outpatients with obsessive???compulsive disorder
Denys, D. A. J. P., van Megen, H. J. G. M., & Westenberg, H. G. M. (2002) · International Clinical Psychopharmacology · doi:10.1097/00004850-200205000-00003 · Cited by 31 · see citing works
Self-citationNicotine augmentation for refractory obsessive-compulsive disorder. A case report
Pasquini, M., Garavini, A., & Biondi, M. (2004) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2004.08.011 · Cited by 31 · see citing works
Olanzapine Augmentation of Fluoxetine in the Treatment of Pathological Skin Picking
Christensen, R. C. (2004) · The Canadian Journal of Psychiatry · doi:10.1177/070674370404901121 · Cited by 28 · see citing works
Carey, P. D., Warwick, J., Harvey, B. H., Stein, D. J., & Seedat, S. (2004) · Metabolic Brain Disease · doi:10.1023/b:mebr.0000027423.34733.12 · Cited by 28 · see citing works
The Role of Venlafaxine in the Treatment of Obsessive—Compulsive Disorder
Phelps, N. J., & Cates, M. E. (2004) · Annals of Pharmacotherapy · doi:10.1345/aph.1e362 · Cited by 27 · see citing works
Bogetto, F., Albert, U., & Maina, G. (2002) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(02)00012-3 · Cited by 26 · see citing works
Dell’Osso, B. M., Allen, A., & Hollander, E. (2005) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.6.15.2727 · Cited by 26 · see citing works
Denys, D. A. J. P., van Megen, H. J. G. M., & Westenberg, H. G. M. (2003) · Journal of Psychopharmacology · doi:10.1177/0269881103017001718 · Cited by 25 · see citing works
Self-citationCitalopram Concentrations and Response in Obsessive-Compulsive Disorder
Bareggi, S. R., Bianchi, L. K., Cavallaro, R., Gervasoni, M., Siliprandi, F., & Bellodi, L. (2004) · CNS Drugs · doi:10.2165/00023210-200418050-00004 · Cited by 21 · see citing works
Kasvikis, Y., & Marks, I. (1988) · Psychopharmacology · doi:10.1007/bf00212778 · Cited by 20 · see citing works
Predicting Treatment Response in Obsessive-Compulsive Disorder
Hurley, R. A., Saxena, S., Rauch, S. L., Hoehn‐Saric, R., & Taber, K. H. (2002) · Journal of Neuropsychiatry · doi:10.1176/jnp.14.3.249 · Cited by 18 · see citing works
Failure of fluoxetine to modify the skin‐picking behaviour of Prader‐Willi syndrome
Schepis, C., Failla, P., Siragusa, M., Palazzo, R., & Romano, C. (1998) · Australasian Journal of Dermatology · doi:10.1111/j.1440-0960.1998.tb01247.x · Cited by 16 · see citing works
Clomipramine Treatment of Sexual Preoccupation
Rubey, R. N., Brady, K. T., & Norris, G. (1993) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199304000-00015 · Cited by 16 · see citing works
Biondi, M., & Picardi, A. (2005) · Psychotherapy and Psychosomatics · doi:10.1159/000083172 · Cited by 16 · see citing works
Mathew, S. J., Coplan, J. D., Perko, K. A., Goetz, R. R., de la Neuz, M., Hollander, E., Liebowitz, M. R., & Fallon, B. A. (2001) · Depression and Anxiety · doi:10.1002/da.1067 · Cited by 14 · see citing works
Efficacy of olanzapine in the treatment of psychogenic excoriation
Blanch, J., Grimalt, F., Massana, G., & Navarro, V. (2004) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2004.06151.x · Cited by 13 · see citing works
Obsessive-Compulsive Disorder: Implications of the Efficacy of an SSRI, Paroxetine
Ninan, P. T., & Beale, M. D. (2015) · Psychopharmacology Bulletin · doi:10.64719/pb.7063 · Cited by 11 · see citing works
Cessation of nail-biting and bupropion.
Wadden, P., & Pawliuk, G. (1999) · PubMed · Cited by 7 · see citing works
Flagged first, then by citations
2 of the 142 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Denys, D., Mantione, M., Figee, M., van den Munckhof, P., Koerselman, F., Westenberg, H., Bosch, A., & Schuurman, R. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.122 · Cited by 763 · see citing works
Self-citationAlonso, P., Cuadras, D., Gabriëls, L., Denys, D., Goodman, W., Greenberg, B. D., Jimenez-Ponce, F., Kuhn, J., Lenartz, D., Mallet, L., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0133591 · Cited by 412 · see citing works
Self-citationShould an obsessive-compulsive spectrum grouping of disorders be included in DSM-V?
Phillips, K. A., Stein, D. J., Rauch, S. L., Hollander, E., Fallon, B. A., BARSKY, A. J., Fineberg, N. A., Mataix‐Cols, D., Ferrão, Y. A., Saxena, S., et al. (2010) · Depression and Anxiety · doi:10.1002/da.20705 · Cited by 349 · see citing works
Luyten, L., Hendrickx, S., Raymaekers, S., Gabriëls, L., & Nuttin, B. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.124 · Cited by 264 · see citing works
Multiple pathways to functional impairment in obsessive-compulsive disorder
Markarian, Y., Larson, M. J., Aldea, M. A., Baldwin, S. A., Good, D., Berkeljon, A., Murphy, T. K., Storch, E. A., & McKay, D. (2010) · Clinical Psychology Review · doi:10.1016/j.cpr.2009.09.005 · Cited by 252 · see citing works
de Koning, P. P., Figee, M., van den Munckhof, P., Schuurman, P. R., & Denys, D. (2011) · Current Psychiatry Reports · doi:10.1007/s11920-011-0200-8 · Cited by 202 · see citing works
Self-citationD-cycloserine does not enhance exposure-response prevention therapy in obsessive-compulsive disorder
Storch, E. A., Merlo, L. J., Bengtson, M., Murphy, T. K., Lewis, M. H., Yang, M. C., Jacob, M. L., Larson, M., Hirsh, A., Fernandez, M., et al. (2007) · International Clinical Psychopharmacology · doi:10.1097/yic.0b013e32819f8480 · Cited by 200 · see citing works
Dopaminergic activity in Tourette syndrome and obsessive-compulsive disorder
Denys, D. A. J. P., de Vries, F., Cath, D. C., Figee, M., Vulink, N. C. C., Veltman, D. J., van der Doef, T. F., Boellaard, R., Westenberg, H. G. M., van Balkom, A. J. L. M., et al. (2013) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2013.05.012 · Cited by 167 · see citing works
Self-citationFineberg, N. A., Hollander, E., Pallanti, S., Walitza, S., Grünblatt, E., Dell’Osso, B. M., Albert, U., Geller, D. A., Brakoulias, V., Janardhan Reddy, Y. C., et al. (2020) · International Clinical Psychopharmacology · doi:10.1097/yic.0000000000000314 · Cited by 161 · see citing works
Denys, D. A. J. P., Graat, I., Mocking, R. J. T., de Koning, P. P., Vulink, N. C. C., Figee, M., Ooms, P., Mantione, M. H. M., van den Munckhof, P., & Schuurman, R. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19060656 · Cited by 159 · see citing works
Self-citationCortico–Basal Ganglia Circuit Function in Psychiatric Disease
Gunaydin, L. A., & Kreitzer, A. C. (2015) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021115-105355 · Cited by 147 · see citing works
Deep Brain Stimulation in the Treatment of Obsessive-Compulsive Disorder
Blomstedt, P. C., Sjöberg, R. L., Hansson, M., Bodlund, O., & Hariz, M. I. (2012) · World Neurosurgery · doi:10.1016/j.wneu.2012.10.006 · Cited by 137 · see citing works
Mantione, M., Nieman, D. H., Figee, M., & Denys, D. (2014) · Psychological Medicine · doi:10.1017/s0033291714000956 · Cited by 129 · see citing works
Self-citationCompulsive features in behavioural addictions: the case of pathological gambling
el‐Guebaly, N., Mudry, T., Zohar, J., Tavares, H., & Potenza, M. N. (2011) · Addiction · doi:10.1111/j.1360-0443.2011.03546.x · Cited by 130 · see citing works
Glutamatergic Synaptic Dysfunction and Obsessive-Compulsive Disorder
Ting, J. T., & Feng, G. (2008) · Current Chemical Genomics · doi:10.2174/1875397300802010062 · Cited by 121 · see citing works
Potenza, M. N., Koran, L. M., & Pallanti, S. (2009) · Psychiatry Research · doi:10.1016/j.psychres.2008.06.036 · Cited by 121 · see citing works
Connectomic deep brain stimulation for obsessive-compulsive disorder
Baldermann, J. C., Schüller, T., Kohl, S., Voon, V., Li, N., Hollunder, B., Figee, M., Haber, S. N., Sheth, S. A., Mosley, P. E., et al. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.07.010 · Cited by 118 · see citing works
Mansur, C. G., Myczkowski, M. L., Cabral, S. D. B., Sartorelli, M. C., Bellini, B. B., Dias, Á. M., Bernik, M., & Marcolin, M. A. (2011) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145711000575 · Cited by 111 · see citing works
Deep brain stimulation for treatment-refractory obsessive compulsive disorder: a systematic review
Kohl, S., Schönherr, D. M., Luigjes, J., Denys, D. A. J. P., Mueller, U. J., Lenartz, D., Visser-Vandewalle, V. E. R. M., & Kuhn, J. (2014) · BMC Psychiatry · doi:10.1186/s12888-014-0214-y · Cited by 110 · see citing works
Self-citationSchaun Korff, A., Stein, D. J., & Harvey, B. H. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.08.032 · Cited by 105 · see citing works
Deep brain stimulation for obsessive-compulsive disorders: long-term analysis of quality of life
Ooms, P., Mantione, M. H. M., Figee, M., Schuurman, P. R., van den Munckhof, P., & Denys, D. A. J. P. (2013) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2012-302550 · Cited by 103 · see citing works
Self-citationDeep brain stimulation for psychiatric disorders: where we are now
Cleary, D. R., Ozpinar, A., Raslan, A. M. T., & Ko, A. L. (2015) · Neurosurgical FOCUS · doi:10.3171/2015.3.focus1546 · Cited by 99 · see citing works
Menchón, J. M., Real, E., Alonso, P., Aparicio, M. A., Segalàs, C., Plans, G., Luyten, L., Brunfaut, E., Matthijs, L., Raymaekers, S., et al. (2019) · Molecular Psychiatry · doi:10.1038/s41380-019-0562-6 · Cited by 94 · see citing works
Maina, G., Pessina, E., Albert, U., & Bogetto, F. (2008) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2008.01.001 · Cited by 92 · see citing works
Deep-brain stimulation for basal ganglia disorders
Wichmann, T., & DeLong, M. R. (2011) · Basal Ganglia · doi:10.1016/j.baga.2011.05.001 · Cited by 89 · see citing works
Karas, P. J., Lee, S., Shahed, J. J., Goodman, W. K., Viswanathan, A., & Sheth, S. A. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00998 · Cited by 89 · see citing works
Animal models of obsessive–compulsive disorder: utility and limitations
Alonso, P., López‐Solà, C., Real, E., Segalàs, C., & Menchón, J. M. (2015) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s62785 · Cited by 84 · see citing works
A Unified Functional Network Target for Deep Brain Stimulation in Obsessive-Compulsive Disorder
Li, N., Hollunder, B., Baldermann, J. C., Kibleur, A., Treu, S., Akram, H., Al‐Fatly, B., Strange, B. A., Barcia, J. A., Zrinzo, L. U., et al. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.04.006 · Cited by 81 · see citing works
Bandelow, B., Allgulander, C., Baldwin, D. S., Costa, D. L. D. C., Denys, D., Dilbaz, N., Domschke, K., Hollander, E., Kasper, S., Möller, H.-J., et al. (2023) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2022.2086296 · Cited by 84 · see citing works
Self-citationGraat, I., Mocking, R. J. T., Figee, M., Vulink, N. C. C., de Koning, P. P., Ooms, P., Mantione, M. H. M., van den Munckhof, P., Schuurman, R., & Denys, D. A. J. P. (2020) · Biological Psychiatry · doi:10.1016/j.biopsych.2020.08.018 · Cited by 73 · see citing works
Self-citationBlom, R. M., Figee, M., Vulink, N. C. C., & Denys, D. A. J. P. (2011) · Current Psychiatry Reports · doi:10.1007/s11920-011-0205-3 · Cited by 72 · see citing works
Self-citationIslam, L., Franzini, A., Messina, G., Scarone, S., & Gambini, O. (2014) · World Neurosurgery · doi:10.1016/j.wneu.2014.12.024 · Cited by 69 · see citing works
A novel, multiple symptom model of obsessive-compulsive-like behaviors in animals.
Andersen, S., Greene-Colozzi, E. A., & Sonntag, K. C. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.05.011 · Cited by 65 · see citing works
van den Munckhof, P., Bosch, D. A., Mantione, M. H. M., Figee, M., Denys, D. A. J. P., & Schuurman, P. R. (2013) · Springer eBooks · doi:10.1007/978-3-7091-1482-7_9 · Cited by 65 · see citing works
Self-citationSurgery for Psychiatric Disorders
Luigjes, J., de Kwaasteniet, B. P., de Koning, P. P., Oudijn, M. S., van den Munckhof, P., Schuurman, P. R., & Denys, D. A. J. P. (2012) · World Neurosurgery · doi:10.1016/j.wneu.2012.03.009 · Cited by 67 · see citing works
Self-citationSelvı, Y., Atlı, A., Aydın, A., Beşiroğlu, L., Özdemir, P. G., & Özdemir, O. (2011) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.1169 · Cited by 64 · see citing works
The anteromedial GPi as a new target for deep brain stimulation in obsessive compulsive disorder
Nair, G., Evans, A. H., Bear, R. E., Velakoulis, D., & Bittar, R. G. (2013) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2013.10.003 · Cited by 64 · see citing works
Clinical outcome and mechanisms of deep brain stimulation for obsessive-compulsive disorder
van Westen, M., Rietveld, E., Figee, M., & Denys, D. (2015) · Current Behavioral Neuroscience Reports · doi:10.1007/s40473-015-0036-3 · Cited by 60 · see citing works
Self-citationSwierkosz-Lenart, K., Santos, J. F. A. D., Elowe, J., Clair, A.-H., Bally, J. F., Riquier, F., Bloch, J., Draganski, B., Clerc, M.-T., Moyano, B. P., et al. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1065812 · Cited by 67 · see citing works
Deep Brain Stimulation for Obsessive-Compulsive Disorder: Optimal Stimulation Sites
Meyer, G. M., Hollunder, B., Li, N., Butenko, K., Dembek, T. A., Hart, L., Nombela, C., Mosley, P. E., Akram, H., Acevedo, N., et al. (2023) · Biological Psychiatry · doi:10.1016/j.biopsych.2023.12.010 · Cited by 58 · see citing works
Raymaekers, S., Vansteelandt, K., Luyten, L., Bervoets, C., Demyttenaere, K., Gabriëls, L. A., & Nuttin, B. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.124 · Cited by 57 · see citing works
Park, Y. S., Sammartino, F., Young, N. A., Corrigan, J. D., Krishna, V., & Rezai, A. R. (2019) · World Neurosurgery · doi:10.1016/j.wneu.2019.01.254 · Cited by 58 · see citing works
Hageman, S. B., van Rooijen, G., Bergfeld, I. O., Schirmbeck, F., de Koning, P., Schuurman, P. R., & Denys, D. (2021) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13276 · Cited by 56 · see citing works
Self-citationvan den Boom, B. J. G., Mooij, A. H., Misevičiūtė, I., Denys, D., & Willuhn, I. (2019) · Genes, Brain and Behavior · doi:10.1111/gbb.12557 · Cited by 55 · see citing works
Self-citationTherapeutic Neurostimulation in Obsessive-Compulsive and Related Disorders: A Systematic Review
Acevedo, N., Bosanac, P., Pikoos, T. D., Rossell, S. L., & Castle, D. J. (2021) · Brain Sciences · doi:10.3390/brainsci11070948 · Cited by 55 · see citing works
Pinhal, C. M., van den Boom, B. J. G., Santana-Kragelund, F., Fellinger, L., Bech, P., Hamelink, R., Feng, G., Willuhn, I., Feenstra, M. G. P., & Denys, D. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2018.05.011 · Cited by 54 · see citing works
Self-citationUmathe, S. N., Bhutada, P., Jain, N. S., Mundhada, Y. R., Borkar, S. S., & Dhumal, B. (2009) · Nitric Oxide · doi:10.1016/j.niox.2009.07.001 · Cited by 54 · see citing works
Neuromodulation in Obsessive-Compulsive Disorder
Bais, M., Figee, M., & Denys, D. (2014) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2014.06.003 · Cited by 53 · see citing works
Self-citationNeurosurgical targets for compulsivity: What can we learn from acquired brain lesions?
Figee, M., Wielaard, I., Mazaheri, A., & Denys, D. A. J. P. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.01.005 · Cited by 53 · see citing works
Self-citationRecent Advances in the Understanding and Treatment of Anxiety Disorders
Shearer, S. L. (2007) · Primary Care Clinics in Office Practice · doi:10.1016/j.pop.2007.05.002 · Cited by 53 · see citing works
Chabardès, S., Krack, P., Piallat, B., Bougerol, T., Seigneuret, É., Yelnik, J., Fernández-Vidal, S., Olivier David, A., Mallet, L., Benabid, A., et al. (2020) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2020-323421 · Cited by 52 · see citing works
LHRH antagonist attenuates the effect of fluoxetine on marble-burying behavior in mice
Gaikwad, U., Bhutada, P., Manish, W., & Umathe, S. N. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.02.016 · Cited by 52 · see citing works
Deep brain stimulation modulates directional limbic connectivity in obsessive-compulsive disorder
Fridgeirsson, E. A., Figee, M., Luigjes, J., van den Munckhof, P., Schuurman, P. R., van Wingen, G., & Denys, D. (2020) · Brain · doi:10.1093/brain/awaa100 · Cited by 51 · see citing works
Self-citationDeep brain stimulation in mental health: Review of evidence for clinical efficacy
Fitzgerald, P. B., & Segrave, R. A. (2015) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867415598011 · Cited by 47 · see citing works
Cortico-striatal oxidative status, dopamine turnover and relation with stereotypy in the deer mouse
Güldenpfennig, M., Wolmarans, D. W., du Preez, J. L., Stein, D. J., & Harvey, B. H. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.03.008 · Cited by 45 · see citing works
Ooms, P., Blankers, M., Figee, M., Bergfeld, I. O., van den Munckhof, P., Schuurman, P. R., & Denys, D. A. J. P. (2017) · Brain stimulation · doi:10.1016/j.brs.2017.04.120 · Cited by 43 · see citing works
Self-citationInvasive and Non-invasive Neurostimulation for OCD
Bergfeld, I. O., Dijkstra, E., Graat, I., de Koning, P. P., van den Boom, B. J. G., Arbab, T., Vulink, N. C. C., Denys, D. A. J. P., Willuhn, I., & Mocking, R. J. T. (2021) · Current topics in behavioral neurosciences · doi:10.1007/7854_2020_206 · Cited by 43 · see citing works
Self-citationAn update on the pharmacological treatment of obsessive-compulsive disorder
Fontenelle, L. F., Nascimento, A. L., Mendlowicz, M. V., Shavitt, R. G., & Versiani, M. (2007) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.8.5.563 · Cited by 42 · see citing works
Denys, D. A. J. P., Fineberg, N. A., Carey, P. D., & Stein, D. J. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.12.014 · Cited by 41 · see citing works
Self-citationUmathe, S. N., Vaghasiya, J. M., Jain, N. S., & Dixit, P. V. (2009) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.06.013 · Cited by 40 · see citing works
The Psychopharmacology of Obsessive-Compulsive Disorder: A Preclinical Roadmap
Szechtman, H., Harvey, B. H., Woody, E. Z., & Hoffman, K. L. (2019) · Pharmacological Reviews · doi:10.1124/pr.119.017772 · Cited by 40 · see citing works
Rolls, E. T. (2012) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.06.017 · Cited by 39 · see citing works
Holland, M. T., Trapp, N. T., McCormick, L. M., Jareczek, F. J., Zanaty, M., Close, L. N., Beeghly, J. H. L., & Greenlee, J. D. W. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00055 · Cited by 38 · see citing works
Off-label prescription of quetiapine in psychiatric disorders
ROWE, D. L. (2007) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.7.7.841 · Cited by 39 · see citing works
Winter, L., Saryyeva, A., Schwabe, K., Heissler, H. E., Runge, J., Alam, M., Heitland, I., Kahl, K. G., & Krauss, J. K. (2020) · Neuromodulation Technology at the Neural Interface · doi:10.1111/ner.13232 · Cited by 38 · see citing works
Farrand, S., Evans, A. H., Mangelsdorf, S., Loi, S. M., Mocellin, R., Borham, A., Bevilacqua, J., Blair‐West, S., Walterfang, M., Bittar, R. G., et al. (2017) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867417731819 · Cited by 36 · see citing works
(2010) · Cited by 35 · see citing works
Behavioral pattern analysis and dopamine release in quinpirole-induced repetitive behavior in rats
de Haas, R., Nijdam, A., Westra, T. A., Kas, M. J., & Westenberg, H. G. M. (2010) · Journal of Psychopharmacology · doi:10.1177/0269881110389093 · Cited by 35 · see citing works
Vinchurney, M. D., Thakre, P. P., Pannase, A. S., Aglawe, M. M., Taksande, B. G., & Kotagale, N. R. (2014) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2014.02.045 · Cited by 34 · see citing works
Genetics of obsessive–compulsive disorder: a research update
Grados, M. A., & Wilcox, H. C. (2007) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.7.8.967 · Cited by 33 · see citing works
Effects of deep brain stimulation on prepulse inhibition in obsessive-compulsive disorder
Kohl, S., Gruendler, T. O. J., Huys, D., Sildatke, E., Dembek, T. A., Hellmich, M., Vorderwulbecke, M., Timmermann, L., Ahmari, S. E., Klosterkoetter, J., et al. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.171 · Cited by 30 · see citing works
Moon, W., Kim, S. N., Park, S. M., Paek, S. H., & Kwon, J. S. (2017) · Medicine · doi:10.1097/md.0000000000007397 · Cited by 30 · see citing works
Muñoz, K. A., Kostick, K. M., Torgerson, L. N., Zuk, P. D., Kalwani, L., Sanchez, C. E., Blumenthal‐Barby, J., Storch, E. A., & Lázaro‐Muñoz, G. (2021) · Brain stimulation · doi:10.1016/j.brs.2021.10.388 · Cited by 29 · see citing works
Tierney, T. S., Abd‐El‐Barr, M. M., Stanford, A. D., Foote, K. D., & Okun, M. S. (2013) · International Journal of Neuroscience · doi:10.3109/00207454.2013.852086 · Cited by 29 · see citing works
Ablative neurosurgery and deep brain stimulation for obsessive-compulsive disorder
Arumugham, S. S., Balachander, S., & Srinivas, D. (2019) · Indian Journal of Psychiatry · doi:10.4103/psychiatry.indianjpsychiatry_523_18 · Cited by 30 · see citing works
Pinto, B. S., Cavendish, B. A., da Silva, P. H. R., Suen, P. J. C., Marinho, K. A. P., Valiengo, L. D. C. L., Vanderhasselt, M., Brunoni, A. R., & Razza, L. B. (2022) · Biomedicines · doi:10.3390/biomedicines11010080 · Cited by 27 · see citing works
Eskenazi, D., & Neumaier, J. F. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07756.x · Cited by 25 · see citing works
Progress and challenges in deep brain stimulation for obsessive-compulsive disorder
Kohl, S., & Baldermann, J. C. (2018) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2018.01.011 · Cited by 25 · see citing works
Psychedelics for the Treatment of Obsessive–Compulsive Disorder: Efficacy and Proposed Mechanisms
Collins, H. M. (2024) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyae057 · Cited by 24 · see citing works
Ashkan, K., Mirza, A. B., Tambirajoo, K., & Furlanetti, L. L. (2020) · European Journal of Paediatric Neurology · doi:10.1016/j.ejpn.2020.09.004 · Cited by 24 · see citing works
Surgical Approaches in Psychiatry: A Survey of the World Literature on Psychosurgery
Neumaier, F., Paterno, M., Alpdogan, S., Tevoufouet, E. E., Schneider, T., Hescheler, J., & Albanna, W. (2016) · World Neurosurgery · doi:10.1016/j.wneu.2016.10.008 · Cited by 24 · see citing works
New Pharmacotherapeutic Approaches to Obsessive-Compulsive Disorder
Figee, M., & Denys, D. A. J. P. (2009) · CNS Spectrums · doi:10.1017/s1092852900027255 · Cited by 24 · see citing works
Self-citationState of the Art: Novel Applications for Deep Brain Stimulation
Roy, H., Green, A. L., & Aziz, T. Z. (2017) · Neuromodulation Technology at the Neural Interface · doi:10.1111/ner.12604 · Cited by 23 · see citing works
Tucci, M. C., Dvorkin‐Gheva, A., Sharma, R., Taji, L., Cheon, P., Peel, J. K., Kirk, A., & Szechtman, H. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3505-6 · Cited by 23 · see citing works
Naesstr, M., Blomstedt, P. C., Hariz, M. I., & Bodlund, O. (2017) · Surgical Neurology International · doi:10.4103/sni.sni_19_17 · Cited by 23 · see citing works
Matsunaga, H., Hayashida, K., Maebayashi, K., 三戸, 宏., & Kiriike, N. (2011) · International Journal of Psychiatry in Clinical Practice · doi:10.3109/13651501.2011.605958 · Cited by 23 · see citing works
Graat, I., Balke, S., Prinssen, J., de Koning, P. P., Vulink, N. C. C., Mocking, R. J. T., van Rooijen, G., van den Munckhof, P., Schuurman, R., & Denys, D. A. J. P. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.12.089 · Cited by 22 · see citing works
Self-citationMahoney, J. J., Koch-Gallup, N., Scarisbrick, D. M., Berry, J. H., & Rezai, A. R. (2022) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2022.120253 · Cited by 21 · see citing works
The potent inhibitory effect of tipepidine on marble-burying behavior in mice
Honda, S., Kawaura, K., Soeda, F., Shirasaki, T., & Takahama, K. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.08.010 · Cited by 20 · see citing works
Cano, M., Alonso, P., Martínez‐Zalacaín, I., Subirà, M., Real, E., Segalàs, C., Pujol, J., Cardoner, N., Menchón, J. M., & Soriano‐Mas, C. (2017) · Psychological Medicine · doi:10.1017/s0033291717002288 · Cited by 20 · see citing works
Yılmaz, Z., Larsen, J. T., Nissen, J. B., Crowley, J. J., Mattheisen, M., Bulik, C. M., & Petersen, L. V. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.02.004 · Cited by 19 · see citing works
Cohen, S. E., Zantvoord, J. B., Storosum, B. W. C., Mattila, T. K., Daams, J. G., Wezenberg, B. N., de Boer, A., & Denys, D. A. J. P. (2024) · BMJ Mental Health · doi:10.1136/bmjment-2023-300951 · Cited by 19 · see citing works
Self-citationAltinay, M. I., Estemalik, E., & Malone, D. A. (2015) · Headache The Journal of Head and Face Pain · doi:10.1111/head.12517 · Cited by 18 · see citing works
Neuromodulation for obsessive-compulsive disorder
Aronson, J. P., Katnani, H. A., & Eskandar, E. N. (2014) · Neurosurgery Clinics of North America · doi:10.1016/j.nec.2013.08.003 · Cited by 18 · see citing works
D-cycloserine augmentation in behavioral therapy for obsessive-compulsive disorder: a meta-analysis
Yu, X., Xia, J., Du, Y., Han, J., & Liu, G. (2015) · Drug Design Development and Therapy · doi:10.2147/dddt.s68994 · Cited by 18 · see citing works
Expanding indications for deep brain stimulation
Doshi, P. (2018) · Neurology India · doi:10.4103/0028-3886.226450 · Cited by 17 · see citing works
Graat, I., van Rooijen, G., Mocking, R. J. T., Vulink, N. C. C., de Koning, P. P., Schuurman, R., & Denys, D. A. J. P. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.11.152 · Cited by 16 · see citing works
Self-citationSchleyken, S., Baldermann, J. C., Huys, D., Franklin, J. G., Visser-Vandewalle, V. E. R. M., Kuhn, J. H., & Kohl, S. (2020) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2020.07.016 · Cited by 17 · see citing works
Starkey, S. R., Morrisey, J. K., Hickam, H. D., Albright, J. D., & Lynch, M. J. (2008) · Journal of Avian Medicine and Surgery · doi:10.1647/2007-037.1 · Cited by 17 · see citing works
Yang, X., Ma, L., Fan, C. G., Wang, H., Zhang, M., Du, H., Zhou, T., & Li, X. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.10.071 · Cited by 16 · see citing works
- Authors
- Denys, D.
- Affiliations
- Utrecht University (NL)
- Corresponding author
- Denys, Damiaan
- ORCID
- Denys, Damiaan
- Venue
- Psychiatric Clinics of North America
- Publisher
- Elsevier BV
- Published
- 2006-06
- Volume
- 29
- Issue
- 2
- Pages
- 553-584
- ISSN
- 0193-953X (ISSN-L)
- OpenAlex
- W2167273704
- Cited by
- 213
- References
- 142
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 18 · 2023: 10 · 2022: 15 · 2021: 16 · 2020: 15 · 2019: 7 · 2018: 9 · 2017: 11 · 2016: 2 · 2015: 16 · 2014: 12 · 2013: 9 · 2012: 4
- FWCI
- 1.44
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychiatric Clinics of North America (publishedVersion)
- PubMed (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Pure Amsterdam UMC (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- obsessive-compulsive disorder, obsessive-compulsive spectrum disorders, pharmacotherapy, serotonin reuptake inhibitors, atypical antipsychotics, treatment-refractory OCD, predictors of treatment response, drug switching, drug delivery
- MeSH terms
- Brain, Clomipramine, Humans, Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy, Fluvoxamine, Selective Serotonin Reuptake Inhibitors, Sertraline, Positron-Emission Tomography
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review