Prevalence and correlates of heavy smoking and nicotine dependence in adolescents with bipolar and cannabis use disorders
Open accessAbstract
The study examined the prevalence and correlates of heavy smoking and nicotine dependence in adolescents with bipolar and cannabis use disorders. Participants were 80 adolescents between 13 and 22 years of age with co-occurring bipolar I disorder and cannabis abuse or dependence who reported ever trying a cigarette. Diagnostic and symptom severity measures were completed as part of the baseline assessments for a clinical trial. Almost half (49%) of these participants who ever tried a cigarette were current heavy smokers (≥10 cigarettes/day), and 70% met DSM-IV-TR lifetime criteria for nicotine dependence. Heavy smoking was associated with older age, heavier marijuana use and greater compulsive craving, lifetime diagnoses of attention-deficit/hyperactivity disorder, conduct disorder, illicit drug use disorders, and poorer overall functioning. Nicotine dependence was related to White race, higher current mania severity, and poorer overall functioning. These findings suggest that heavy smoking and nicotine dependence were highly prevalent among these adolescents. Although both were associated with greater physical and psychosocial problems, only heavy smoking was linked to a clear pattern of more severe substance-related and psychiatric problems. Further research to elucidate mechanisms and develop interventions to address early, entrenched patterns of co-use of tobacco and marijuana is warranted.
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Heavy smoking in adolescents with bipolar disorder paves the way to heavier marijuana use, illicit drug use disorders, and poorer overall functioning.
“Heavy smoking in adolescents with BD also paves the way to heavier marijuana use, illicit drug use disorders, and poorer overall functioning (13).”
From The detrimental effects of smoking on the course and outcome in adults with bipolar disorder—A narrative review (2023) · cites this paper as [13]
Results §3.1 associates heavy smoking with more marijuana use, illicit drug use disorders, and poorer functioning among adolescents with both bipolar and cannabis use disorders. Discussion §4 explicitly says causality cannot be determined, so the claim’s “paves the way” wording overstates the finding; the study also does not establish it for adolescents with bipolar disorder generally. (LLM, conf=0.90)
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- Authors
- Heffner, J. L., Anthenelli, R. M., Adler, C. M., Strakowski, S. M., Beavers, J., & DelBello, M. P.
- Affiliations
- University of Cincinnati (US)
- University of California San Diego (US)
- Corresponding author
- Heffner, Jaimee L.
- ORCID
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 2013-12
- Volume
- 210
- Issue
- 3
- Pages
- 857-862
- ISSN
- 0165-1781 (ISSN-L)
- PMC
- PMC3899029
- OpenAlex
- W2009040232
- Cited by
- 22
- References
- 39
- Citations by year
- 2023: 2 · 2022: 2 · 2021: 3 · 2019: 1 · 2018: 3 · 2017: 1 · 2016: 3 · 2015: 3 · 2014: 4
- FWCI
- 2.31
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychiatry Research (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Institutes of Health (K23DA026517, R01DA022221)
- National Institute on Drug Abuse
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- adolescent smoking, heavy smoking, nicotine dependence, bipolar disorder, cannabis use disorder, co-occurring substance use disorders, mania severity, attention deficit hyperactivity disorder, conduct disorder, prevalence
- MeSH terms
- Adolescent, Age Factors, Attention Deficit Disorder with Hyperactivity, Bipolar Disorder, Cannabis, Marijuana Abuse, Female, Health Surveys, Humans, Male, Marijuana Smoking, Surveys and Questionnaires, Smoking, Tobacco Use Disorder, United States, Prevalence, Diagnostic and Statistical Manual of Mental Disorders, Young Adult
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