Cited by 179Smoking Behavior and CessationBipolar Disorder and TreatmentSubstance Abuse Treatment and Outcomes

Tobacco smoking behaviors in bipolar disorder: a comparison of the general population, schizophrenia, and major depression

Diaz, Francisco J, James, Danielle, Botts, Sheila, Maw, Lorraine, Susce, Margaret T, De Leon, Jose·2009·Bipolar Disorders

Abstract

OBJECTIVES: This study compared the prevalence of tobacco smoking behaviors in patients with bipolar disorder with normal and psychiatric (schizophrenia and major depression) controls. The main goal was to establish that bipolar patients smoke more than normal controls. Differences with psychiatric controls were explored. METHODS: Samples of 424 patients (99 bipolar, 258 schizophrenia and 67 major depression) and 402 volunteer controls were collected in Central Kentucky. Smoking data for Kentucky's general population were available. Odds ratios (ORs) and their 95% confidence intervals (CIs) were used to establish the strength of associations. Logistic regression was used to adjust ORs for confounding variables. RESULTS: Using epidemiological definitions of smoking behaviors and the general population as controls provided bipolar disorder unadjusted ORs of 5.0 (95% CI: 3.3-7.8) for current cigarette smoking, 2.6 (95% CI: 1.7-4.4) for ever cigarette smoking, and 0.13 (95% CI: 0.03-0.24) for smoking cessation. Using a clinical definition and volunteers as controls provided respective bipolar disorder adjusted ORs of 7.3 (95% CI: 4.3-12.4), 4.0 (95% CI: 2.4-6.7), and 0.15 (95% CI: 0.06-0.36). Prevalences of current daily smoking for patients with major depression, bipolar disorder, and schizophrenia were 57%, 66%, and 74%, respectively. CONCLUSIONS: Bipolar disorder was associated with significantly higher prevalences of tobacco smoking behaviors compared with the general population or volunteer controls, independently of the definition used. It is possible that smoking behaviors in bipolar disorder may have intermediate prevalences between major depression and schizophrenia, but larger samples or a combination of multiple studies (meta-analysis) will be needed to establish whether this hypothesis is correct.

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Crossref · 10.1111/j.1399-5618.2009.00664.x

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  • The prevalence of everyday current smoking is 66% in people with bipolar disorder in a Kentucky catchment area study, significantly elevated compared to the general population and exceeding rates in major depression and schizophrenia.

    “A catchment area study from Kentucky reports that the prevalence of everyday current smoking is 66% in people with BD, which is also significantly elevated when compared to the general population, and also exceeds the rate observed in people with major depression and schizophrenia (9).”

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Authors
Diaz, F. J., James, D., Botts, S., Maw, L., Susce, M. T., & De Leon, J.
Affiliations
University of Kentucky (US)
Venue
Bipolar Disorders
Publisher
Wiley
Published
2009-02-25
Volume
11
Issue
2
Pages
154-165
ISSN
  • 1398-5647 (ISSN-L)
  • 1399-5618
OpenAlex
W1979173012
Cited by
179
References
49
Citations by year
2026: 6 · 2025: 2 · 2024: 2 · 2023: 5 · 2022: 12 · 2021: 6 · 2020: 10 · 2019: 8 · 2018: 6 · 2017: 12 · 2016: 6 · 2015: 20 · 2014: 6 · 2013: 12 · 2012: 24
FWCI
14.36
Type
journal article
Language
en
Open access
closed
Locations
  • Bipolar Disorders (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
  • Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords
smoking, bipolar disorder, schizophrenia, major depressive disorder, smoking prevalence, smoking cessation, psychiatric comorbidity
MeSH terms
Adult, Bipolar Disorder, Major Depressive Disorder, Female, Humans, Male, Middle Aged, Schizophrenia, Schizophrenic Psychology, Smoking, Prevalence, Confidence Intervals, Odds Ratio, Population Groups

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