Anger temperament is modestly associated with the risk of type 2 diabetes mellitus: The atheroslcerosis risk in communities study
Abstract
Objective Trait anger has been shown to predict coronary heart disease; however, there are no prior studies evaluating anger as a risk factor for type 2 diabetes. The objective of this study was to determine if anger proneness predicted type 2 diabetes using prospective analyses. Methods We analyzed data on trait anger, assessed by questionnaire, in a longitudinal, bi-racial cohort study of 11,615 initially non-diabetic adults aged 48-67, who were subsequently followed for 6 years for the development of type 2 diabetes. Results There was no relation between overall trait anger and the subsequent risk of diabetes; however, individuals in the highest tertile of trait anger temperament scores had a 34% increased risk of developing diabetes compared to those in the lowest tertile (Relative hazard [RH] = 1.34; 95% confidence interval: 1.10, 1.62), following adjustment for age, race, gender, and education. The relation between anger temperament and diabetes remained significant following adjustment for behavioral factors (smoking, physical activity, and caloric intake) (RH = 1.31; 95% CI: 1.08, 1.60) but was non-significant after additional adjustment for waist-to-hip ratio and body-mass index (RH = 1.18; 95% CI: 0.97, 1.44). Conclusions While we found no relation between overall trait anger and incident diabetes, persons who had higher anger temperament subscale scores had a slightly increased risk of type 2 diabetes, which was largely explained by adiposity. Anger temperament may deserve further attention as a potential risk factor for type 2 diabetes.
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In the Atherosclerosis Risk in Communities Study of 11,615 participants, trait anger was associated with an increased risk of future T2DM independent of covariates.
“In the Atherosclerosis Risk in Communities Study of 11,615 participants, trait anger was associated with an increased risk of future T2DM independent of covariates 86”
From Type 2 diabetes mellitus and psychological stress — a modifiable risk factor (2017) · cites this paper as [86]
In the ARIC cohort (n=11,615; 6-year mean follow-up), anger using the Spielberger trait anger scale (ten item) was associated with incident diabetes mellitus (HR 1.34, 95% CI 1.10-1.62).
“ARIC cohort ( n = 11,615; 6 year mean follow-up) | Anger using the Spielberger trait anger scale (ten item) | *HR 1.34 (95% CI 1.10- 1.62).”
From Type 2 diabetes mellitus and psychological stress — a modifiable risk factor (2017) · cites this paper as Golden (2006) 80
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- Authors
- Golden, S. H., Williams, J. E., Ford, D. E., Yeh, H.-C., Sanford, C. P., Nieto, F. J., & Brancati, F. L.
- Affiliations
- Johns Hopkins University (US)
- NC Department of Health and Human Services (US)
- University of Wisconsin–Madison (US)
- Corresponding author
- Golden, Sherita Hill
- ORCID
- Golden, Sherita Hill
- Venue
- Psychoneuroendocrinology
- Publisher
- Elsevier BV
- Published
- 2006-04
- Volume
- 31
- Issue
- 3
- Pages
- 325-332
- ISSN
- 0306-4530 (ISSN-L)
- OpenAlex
- W2134141628
- Cited by
- 55
- References
- 30
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 2 · 2023: 6 · 2022: 4 · 2021: 2 · 2020: 2 · 2019: 3 · 2018: 1 · 2017: 1 · 2016: 5 · 2015: 4 · 2014: 2 · 2013: 2 · 2012: 5
- FWCI
- 1.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychoneuroendocrinology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (n01hc55021-47-0-1, n01hc55020-39-0-0, n01hc55016-37-0-0, n01hc055022-024, n01hc55019-35-0-1, n01hc55018-38-0-1, n01hc55015-48-0-1)
- National Heart, Lung, and Blood Institute (N01-HC55022, N01-HC-55018, N01 HC 55020, N01 HC 55019, N01-HC55016, N01‐HC‐55015, N01-HC55021)
- National Institute of Diabetes and Digestive and Kidney Diseases (IK24-DK6222-01)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
- Keywords
- type 2 diabetes, diabetes risk factors, trait anger, adiposity, body mass index, waist-to-hip ratio, psychosocial risk factors, Atherosclerosis Risk in Communities Study, middle-aged adults
- MeSH terms
- Aged, Anger, Anthropometry, Blood Chemical Analysis, Diabetes Mellitus, Type 2, Female, Follow-Up Studies, Humans, Longitudinal Studies, Male, Middle Aged, Personality, Predictive Value of Tests, Prospective Studies, Risk Factors, United States, Cohort Studies, Atherosclerosis
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