Higher levels of psychological distress are associated with a higher risk of incident diabetes during 18 year follow-up: results from the British household panel survey
Open accessAbstract
BACKGROUND: Reviews have shown that depression is a risk factor for the development of type 2 diabetes. However, there is limited evidence for general psychological distress to be associated with incident diabetes. The aim of the present study was to test whether persons who report higher levels of psychological distress are at increased risk to develop type 2 diabetes during 18 years follow up, adjusted for confounders. METHODS: A prospective analysis using data from 9,514 participants (41 years, SD=14; 44% men) of the British Household Panel Survey. The General Health Questionnaire 12 item version was used to assess general psychological distress, diabetes was measured by means of self-report. Cox proportional hazards regression models were used to calculate the multivariate-adjusted hazard ratio (HR) of incident diabetes during 18 years follow up, comparing participants with low versus high psychological distress at baseline (1991). RESULTS: A total of 472 participants developed diabetes 18 year follow up. Those with a high level of psychological distress had a 33% higher hazard of developing diabetes (HR=1.33, 95% CI 1.10-1.61), relative to those with a low level of psychological distress, adjusted for age, sex, education level and household income. After further adjustment for differences in level of energy, health status, health problems and activity level, higher psychological distress was no longer associated with incident diabetes (HR=1.10, 95% CI 0.91-1.34). CONCLUSIONS: Higher levels of psychological distress are a risk factor for the development of diabetes during an 18 year follow up period. This association may be potentially mediated by low energy level and impaired health status.
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In the largest study, psychological distress was associated with future development of diabetes mellitus, but the association was attenuated after controlling for health behaviours.
“The largest study found an association between psychological distress and future development of diabetes mellitus, but the finding was attenuated after controlling for health behaviours 75”
From Type 2 diabetes mellitus and psychological stress — a modifiable risk factor (2017) · cites this paper as [75]
Table 3 reports an association between psychological distress and incident diabetes after sociodemographic adjustment (HR 1.33), which fell to HR 1.10 after adjustment for energy level and health status. Adding the lifestyle factors did not further attenuate it (HR 1.10). The claim is therefore right about the association and attenuation, but attributes the attenuation to health behaviours rather than the health factors identified in the paper. (LLM, conf=0.90)
Experimental — accuracy not yet measuredIn UK adults (n=9,514; 18-year follow-up), psychological distress measured by the 12-item general health questionnaire was associated with incident diabetes mellitus (HR 1.33, 95% CI 1.10-1.61), attenuated controlling for health behaviours.
“UK adults ( n = 9,514; 18 year follow-up) | Psychological distress using the 12- item general health questionnaire | *HR 1.33 (95% CI 1.10-1.61). Attenuated controlling for health behaviours.”
From Type 2 diabetes mellitus and psychological stress — a modifiable risk factor (2017) · cites this paper as Mommersteeg (2012)
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- Authors
- Mommersteeg, P. M., Herr, R., Zijlstra, W. P., Schneider, S., & Pouwer, F.
- Affiliations
- Tilburg University (NL)
- Corresponding author
- Mommersteeg, Paula MC
- Venue
- BMC Public Health
- Published
- 2012-12
- Volume
- 12
- Issue
- 1
- Pages
- 1109-1109
- ISSN
- 1471-2458 (ISSN-L)
- PMC
- PMC3551824
- OpenAlex
- W2099776907
- Cited by
- 58
- References
- 35
- Citations by year
- 2025: 2 · 2024: 4 · 2023: 6 · 2022: 6 · 2021: 4 · 2020: 2 · 2019: 2 · 2018: 4 · 2017: 5 · 2016: 8 · 2015: 4 · 2014: 6 · 2013: 5
- FWCI
- 3.85
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- BMC Public Health (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- Research portal (Tilburg University) (publishedVersion, other-oa)
- PubMed (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- University of Essex
- Economic and Social Research Council
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Social Sciences › Health › Health disparities and outcomes
- Keywords
- psychological distress, type 2 diabetes, incident diabetes risk, depression, General Health Questionnaire, energy intake, health status, British Household Panel Survey
- MeSH terms
- Adult, Diabetes Mellitus, Type 2, Female, Follow-Up Studies, United Kingdom, Health Surveys, Humans, Male, Middle Aged, Prospective Studies, Risk Factors, Stress, Psychological, Incidence, Risk Assessment
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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