CoChat
Sign Up
Cited by 128Reproductive Health and ContraceptionEstrogen and related hormone effectsSpatial Cognition and Navigation

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Effects of hormonal contraceptives on mental rotation and verbal fluency

Griksiene, Ramune, Ruksenas, Osvaldas·2011·Psychoneuroendocrinology
DOI 10.1016/j.psyneuen.2011.03.001
Open this paper in CoChat — free account

Abstract

Cognitive abilities, such as verbal fluency and mental rotation, are most sensitive to changes in sex steroids but poorly studied in the context of hormonal contraceptive usage. Therefore, we investigated the performance of mental rotation and verbal fluency in young (21.5±1.8 years) healthy oral contraceptive (OC) users (23 women) and non-users (20 women) during the follicular, ovulatory and luteal phases of the menstrual cycle. Salivary 17β-estradiol, progesterone and testosterone levels were assayed to evaluate hormonal differences between groups and the phases of the menstrual cycle. To assess the effects of progestins having androgenic/anti-androgenic properties, OC users were subdivided into the third and new generation OC users. In addition, positive and negative affects as factors possibly affecting cognitive performance were evaluated. Salivary 17β-estradiol and progesterone levels were significantly lower in hormonal contraception users. Level of salivary testosterone was slightly lower in the OC users group with significant difference only during ovulatory phase. Naturally cycling women performed better on verbal fluency task as compared to OC users. Subjects who used the third generation (androgenic) OCs generated significantly fewer words as compared to new generation (anti-androgenic) OC users and non-users. The third generation OC users demonstrated significantly longer RT in MRT task as compared to non-users. The MRT, verbal fluency and mood parameters did not…

Overview

Integrity signals

Registry

Crossref · 10.1016/j.psyneuen.2011.03.001

Cites

0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 48

  1. Aleman, 2004, A single administration of testosterone improves visuospatial ability in young women, Psychoneuroendocrinology, 29, 612, 10.1016/S0306-4530(03)00089-1 · DOI
  2. Almagor, 1991, Mood changes during the menstrual cycle and their relation to the use of oral contraceptive, J. Psychosom. Res., 35, 721, 10.1016/0022-3999(91)90123-6 · DOI
  3. Amy, 2009, Contraception for women: an evidence based overview, BMJ, 339, b2895, 10.1136/bmj.b2895 · DOI
  4. Batur, 2003, Update on contraception: benefits and risks of the new formulations, Cleve. Clin. J. Med., 70, 10.3949/ccjm.70.8.681 · DOI
  5. Benagiano, 2009, Safety, efficacy and patient satisfaction with continuous daily administration of levonorgestrel/ethinylestradiol oral contraceptives, Patient. Prefer. Adherence, 3, 131, 10.2147/PPA.S3692 · DOI
  6. Borod, 1984, The target test: a brief laterality measure of speed and accuracy, Percept. Mot. Skills, 58, 743, 10.2466/pms.1984.58.3.743 · DOI
  7. Brown, 2008, Well-being, sleep, exercise patterns, and the menstrual cycle: a comparison of natural hormones, oral contraceptives and depo-provera, Women Health, 47, 105, 10.1300/J013v47n01_06 · DOI
  8. Carr, 1998, Uniqueness of oral contraceptive progestins, Contraception, 58, 23S, 10.1016/S0010-7824(98)00079-1 · DOI
  9. Epting, 1998, Sex-sensitive tasks in men and women: a search for performance fluctuations across the menstrual cycle, Behav. Neurosci., 112, 1304, 10.1037/0735-7044.112.6.1304 · DOI
  10. Farrag, 2002, Effect of surgical menopause on cognitive functions, Dement. Geriatr. Cogn. Disord., 13, 193, 10.1159/000048652 · DOI
  11. Glasier, 2006, Combined hormonal contraception, Medicine, 34, 1, 10.1383/medc.2006.34.1.1 · DOI
  12. Gordon, 1993, No difference in cognitive performance between phases of the menstrual cycle, Psychoneuroendocrinology, 18, 521, 10.1016/0306-4530(93)90045-M · DOI
  13. Gouchie, 1991, The relationship between testosterone levels and cognitive ability patterns, Psychoneuroendocrinology, 16, 323, 10.1016/0306-4530(91)90018-O · DOI
  14. Griksiene, 2009, Cognitive effects of hormone-based contraception in young healthy women, Biologija, 55, 115, 10.2478/v10054-009-0018-z · DOI
  15. Halari, 2006, Comparable fMRI activity with differential behavioural performance on mental rotation and overt verbal fluency tasks in healthy men and women, Exp. Brain Res., 169, 1, 10.1007/s00221-005-0118-7 · DOI
  16. Hampson, 1990, Estrogen-related variations in human spatial and articulatory-motor skills, Psychoneuroendocrinology, 15, 97, 10.1016/0306-4530(90)90018-5 · DOI
  17. Hausmann, 2000, Steroid fluctuations modify functional cerebral asymmetries: the hypothesis of progesterone-mediated interhemispheric decoupling, Neuropsychologia, 38, 1362, 10.1016/S0028-3932(00)00045-2 · DOI
  18. Hausmann, 2009, Interactive effects of sex hormones and gender stereotypes on cognitive sex differences – a psychobiosocial approach, Psychoneuroendocrinology, 34, 389, 10.1016/j.psyneuen.2008.09.019 · DOI
  19. Hausmann, 2000, Sex hormones affect spatial abilities during the menstrual cycle, Behav. Neurosci., 114, 1245, 10.1037/0735-7044.114.6.1245 · DOI
  20. Jansen, 2010, Gender differences in mental rotation across adulthood, Exp. Aging Res., 36, 94, 10.1080/03610730903422762 · DOI
  21. Kozaki, 2009, Sex differences on components of mental rotation at different menstrual phases, Int. J. Neurosci., 119, 59, 10.1080/00207450802480101 · DOI
  22. Liening, 2010, Salivary testosterone, cortisol, and progesterone: two-week stability, interhormone correlations, and effects of time of day, menstrual cycle, and oral contraceptive use on steroid hormone levels, Physiol. Behav., 99, 8, 10.1016/j.physbeh.2009.10.001 · DOI
  23. Lu, 1999, Salivary estradiol and progesterone levels in conception and nonconception cycles in women: evaluation of a new assay for salivary estradiol, Fertil. Steril., 71, 863, 10.1016/S0015-0282(99)00093-X · DOI
  24. Maki, 2002, Implicit memory varies across the menstrual cycle: estrogen effects in young women, Neuropsychologia, 40, 518, 10.1016/S0028-3932(01)00126-9 · DOI
  25. Matousek, 2010, Sex steroid hormones and cognitive functioning in healthy, older men, Horm. Behav., 57, 352, 10.1016/j.yhbeh.2010.01.004 · DOI
  26. Moffat, 1996, A curvilinear relationship between testosterone and spatial cognition in humans: possible influence of hand preference, Psychoneuroendocrinology, 21, 323, 10.1016/0306-4530(95)00051-8 · DOI
  27. Mordecai, 2008, Effects of menstrual cycle phase and oral contraceptive use on verbal memory, Horm. Behav., 54, 286, 10.1016/j.yhbeh.2008.03.006 · DOI
  28. Oinonen, 2002, To what extent do oral contraceptives influence mood and affect?, J. Affect. Disord., 70, 229, 10.1016/S0165-0327(01)00356-1 · DOI · Paper page
  29. Ossewaarde, 2010, Neural mechanisms underlying changes in stress-sensitivity across the menstrual cycle, Psychoneuroendocrinology, 35, 47, 10.1016/j.psyneuen.2009.08.011 · DOI · Paper page
  30. Ostatnikova, 2002, testosterone levels and their fluctuations influence cognitive performance in humans?, Scr. Med. (Brno), 75, 245
  31. Peters, 2008, Applications of mental rotation figures of the shepard and metzler type and description of a mental rotation stimulus library, Brain Cogn., 66, 260, 10.1016/j.bandc.2007.09.003 · DOI
  32. Peters, 2006, Mental rotation test performance in four cross-cultural samples (n=3367): overall sex differences and the role of academic program in performance, Cortex, 42, 1005, 10.1016/S0010-9452(08)70206-5 · DOI
  33. Rosenberg, 2002, Verbal and spatial functions across the menstrual cycle in healthy young women, Psychoneuroendocrinology, 27, 835, 10.1016/S0306-4530(01)00083-X · DOI · Paper page
  34. Rowlands, 2003, Newer progestogens, J. Fam. Plann. Reprod. Health Care, 29, 13, 10.1783/147118903101197188 · DOI
  35. Rumberg, 2010, Cycle and gender-specific cerebral activation during a verb generation task using fMRI: comparison of women in different cycle phases, under oral contraception, and men, Neurosci. Res., 66, 366, 10.1016/j.neures.2009.12.011 · DOI
  36. Shepard, 1971, Mental rotation of three-dimensional objects, Science, 171, 701, 10.1126/science.171.3972.701 · DOI · Paper page
  37. Sherwin, 2006, Estrogen and cognitive aging in women, Neuroscience, 138, 1021, 10.1016/j.neuroscience.2005.07.051 · DOI
  38. Silinskas, 2004, Correlates of subjective well-being in male sample, Psichologija, 30, 47, 10.15388/Psichol.2004..4347 · DOI
  39. Slabbekoorn, 1999, Activating effects of cross-sex hormones on cognitive functioning: a study of short-term and long-term hormone effects in transsexuals, Psychoneuroendocrinology, 24, 423, 10.1016/S0306-4530(98)00091-2 · DOI
  40. van Anders, 2010, Chewing gum has large effects on salivary testosterone, estradiol, and secretory immunoglobulin A assays in women and men, Psychoneuroendocrinology, 35, 305, 10.1016/j.psyneuen.2009.06.009 · DOI
  41. Van Goozen, 1995, Gender differences in behavior: activating effects of cross-sex hormones, Psychoneuroendocrinology, 20, 343, 10.1016/0306-4530(94)00076-X · DOI
  42. van Heusden, 1999, Activity of the pituitary-ovarian axis in the pill-free interval during use of low-dose combined oral contraceptives, Contraception, 59, 237, 10.1016/S0010-7824(99)00025-6 · DOI
  43. Vandenberg, 1978, Mental rotations, a group test of three-dimensional spatial visualization, Percept. Mot. Skills., 47, 599, 10.2466/pms.1978.47.2.599 · DOI · Paper page
  44. Wallentin, 2009, Putative sex differences in verbal abilities and language cortex: a critical review, Brain Lang., 108, 175, 10.1016/j.bandl.2008.07.001 · DOI
  45. Watson, 1988, Development and validation of brief measures of positive and negative affect: the PANAS scales, J. Pers. Soc. Psychol., 54, 1063, 10.1037/0022-3514.54.6.1063 · DOI · Paper page
  46. Weiss, 2003, Sex differences in cognitive functions, Pers. Individ. Differ., 35, 863, 10.1016/S0191-8869(02)00288-X · DOI
  47. Wharton, 2008, Oral contraceptives and androgenicity: influences on visuospatial task performance in younger individuals, Exp. Clin. Psychopharmacol., 16, 156, 10.1037/1064-1297.16.2.156 · DOI
  48. Yang, 2007, Testosterone levels and mental rotation performance in Chinese men, Horm. Behav., 51, 373, 10.1016/j.yhbeh.2006.12.005 · DOI · Paper page

Cited by

Sorted by citations

See all 128

Metadata

Authors
Griksiene, R., & Ruksenas, O.
Venue
Psychoneuroendocrinology
Publisher
Elsevier BV
Published
2011-09
Volume
36
Issue
8
Pages
1239-1248
ISSN
0306-4530 (ISSN-L)
DOI
10.1016/j.psyneuen.2011.03.001
OpenAlex
W2011880684
Cited by
128
References
0
Citations by year
2026: 4 · 2025: 10 · 2024: 4 · 2023: 9 · 2022: 16 · 2021: 9 · 2020: 16 · 2019: 9 · 2018: 9 · 2017: 5 · 2016: 10 · 2015: 6 · 2014: 10 · 2013: 9 · 2012: 1
FWCI
6.61
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Psychoneuroendocrinology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Health and Contraception
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Spatial Cognition and Navigation
Keywords
oral contraceptives, mental rotation, verbal fluency, progestins, androgenic progestins, salivary estradiol, salivary progesterone, salivary testosterone, menstrual cycle phases, cognitive performance, spatial ability, mood, young women
MeSH terms
Adult, Affect, Contraceptives, Oral, Hormonal, Female, Humans, Male, Mental Processes, Neuropsychological Tests, Rotation, Space Perception, Task Performance and Analysis, Verbal Behavior, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review