The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
La depresión: un predictor de demencia
Abstract
Many studies suggest that in 10-25% of cases of Alzheimer's, the most common dementia in our society, can be prevented with the elimination of some risk factors. Barnes and Yaffe found that one-third of Alzheimer's cases are attributable to depression, but in the scientific literature it is not clear if it has a real causal effect on the development of dementia. The purpose of this study is to analyse the scientific evidence on the hypothesis that depression increases the risk of developing dementia. A systematic review and a meta-analysis were performed on the scientific literature published up until the present day, searching articles that were published between 1990 and 2014. Ten of the studies found met the selection criteria -similar to a) size and characteristics of the sample (origin, age…), b) process of gathering data c) method of studying the relationship (within and/or between group comparison), and d) statistical analysis of the results- and the previously established quality. The value of odds ratio varied from 1.72 to 3.59, and the hazard ratio from 1,72 to 5.44. This indicates that the subjects with a history of depression have a higher risk of developing dementia than others who did not suffer depression.
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Studies investigating the relationship between antidepressant use and AD/ADRD risk have yielded conflicting results.
“Studies looking into this question, however, have yielded conflicting results. 4-7”
From Antidepressant exposure and long‐term dementia risk in a nationwide retrospective study on US veterans with midlife major depressive disorder (2024) · cites this paper as [5]
Citations
Cites
Recurrent depressive symptoms and the incidence of dementia and mild cognitive impairment
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Cited by
Sorted by citations
Ramos‐Cejudo, J., Corrigan, J. K., Zheng, C., Swinnerton, K. N., Jacobson, S. R., La, J., Betensky, R. A., Osorio, R. S., Madanes, S., Pomara, N., et al. (2024) · Alzheimer's & Dementia · doi:10.1002/alz.13853 · Cited by 11
Metadata
- Authors
- Deví Bastida, J., Puig Pomés, N., Jofre Font, S., & Fetscher Eickhoff, A.
- Venue
- Revista Española de Geriatría y Gerontología
- Publisher
- Elsevier BV
- Published
- 2016-03
- Volume
- 51
- Issue
- 2
- Pages
- 112-118
- ISSN
- 0211-139X (ISSN-L)
- OpenAlex
- W2183492123
- Cited by
- 19
- References
- 3
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 6 · 2022: 1 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 2
- FWCI
- 0.09
- Type
- journal article
- Language
- es
- Open access
- closed
- Locations
- Revista Española de Geriatría y Gerontología (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Keywords
- depression, dementia, Alzheimer's disease, dementia risk, depression as risk factor, dementia prevention, risk factors, odds ratio, hazard ratio, attributable fraction, meta-regression, publication bias, study quality assessment, cognitive screening
- MeSH terms
- Aged, Dementia, Depression, Depressive Disorder, Humans, Risk Factors
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