Cited by 19Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatmentsTreatment of Major Depression

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La depresión: un predictor de demencia

Deví Bastida, Josep, Puig Pomés, Núria, Jofre Font, Susanna, Fetscher Eickhoff, Albert·2016·Revista Española de Geriatría y Gerontología

Abstract

Many studies suggest that in 10-25% of cases of Alzheimer's, the most common dementia in our society, can be prevented with the elimination of some risk factors. Barnes and Yaffe found that one-third of Alzheimer's cases are attributable to depression, but in the scientific literature it is not clear if it has a real causal effect on the development of dementia. The purpose of this study is to analyse the scientific evidence on the hypothesis that depression increases the risk of developing dementia. A systematic review and a meta-analysis were performed on the scientific literature published up until the present day, searching articles that were published between 1990 and 2014. Ten of the studies found met the selection criteria -similar to a) size and characteristics of the sample (origin, age…), b) process of gathering data c) method of studying the relationship (within and/or between group comparison), and d) statistical analysis of the results- and the previously established quality. The value of odds ratio varied from 1.72 to 3.59, and the hazard ratio from 1,72 to 5.44. This indicates that the subjects with a history of depression have a higher risk of developing dementia than others who did not suffer depression.

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Research works printed but not linked: 45

  1. Prince, 2013, The global prevalence of dementia: A systematic review and metaanalysis, Alzheimers Dement., 9, 63, 10.1016/j.jalz.2012.11.007 · DOI · Paper page
  2. Norton, 2014, Potential for primary prevention of Alzheimer's disease: an analysis population-based data, Lancet Neurol., 13, 788, 10.1016/S1474-4422(14)70136-X · DOI · Paper page
  3. Barnes, 2011, The projected effect of risk factor reduction on Alzheimer's disease prevalence, Lancet Neurol., 819, 10.1016/S1474-4422(11)70072-2 · DOI
  4. Andersen, 2005, Depression and the risk of Alzheimer disease, Epidemiol., 16, 233, 10.1097/01.ede.0000152116.32580.24 · DOI
  5. Buntinx, 1996, Is depression in elderly people followed by dementia?. A retrospective cohort study based in general practice, Age Ageing., 25, 231, 10.1093/ageing/25.3.231 · DOI · Paper page
  6. Dal Forno, 2005, Depressive symptoms, sex, and risk for Alzheimer's disease, Ann Neurol, 57, 381, 10.1002/ana.20405 · DOI
  7. Green, 2003, Depression as a risk factor for Alzheimer disease: the MIRAGE Study, Arch Neurol., 60, 753, 10.1001/archneur.60.5.753 · DOI · Paper page
  8. Kessing, 2003, Increased risk of developing dementia in patients with major affective disorders compared to patients with other medical illnesses, J Affect Disord., 73, 261, 10.1016/S0165-0327(02)00004-6 · DOI
  9. Ownby, 2006, Depression and risk for Alzheimer disease: systematic review, meta-analysis, and metaregression analysis, Arch Gen Psychiatry., 63, 530, 10.1001/archpsyc.63.5.530 · DOI · Paper page
  10. López Trigo, 2001, La depresión en el paciente anciano, Rev Esp Geriatr Gerontol., 3
  11. Forsell, 1998, Major depression in a population of demented and nondemented older people: prevalence and correlates, J Am Geriatr Soc., 46, 27, 10.1111/j.1532-5415.1998.tb01009.x · DOI
  12. Jost, 1996, The evolution of psychiatric symptoms in Alzheimer's disease: a natural history study, J Am Geriatr Soc., 44, 1078, 10.1111/j.1532-5415.1996.tb02942.x · DOI
  13. Bolland, 2000, Depression in Alzheimer's disease and other dementias, Curr Psychiatr Repor., 2, 427, 10.1007/s11920-000-0028-0 · DOI
  14. Vilalta-Franch, 1999, Depression and dementia: case-control study, Rev Neurol., 29, 599, 10.33588/rn.2907.99240 · DOI
  15. Vilalta-Franch, 1998, Prevalence of depressive disorders in dementia, Rev Neurol., 26, 57
  16. Förstl, 1992, Clinical and neuropathological correlates of depression in Alzheimer's disease, Psychol Med., 22, 877, 10.1017/S0033291700038459 · DOI
  17. Masters, 2015, «Noncognitive» symptoms of early Alzheimer disease, Neurology., 84, 617, 10.1212/WNL.0000000000001238 · DOI
  18. Mah, 2015, Anxiety symptoms in amnestic mild cognitive impairment are associated with medial temporal atrophy and predict conversion to Alzheimer disease, Am J Geriatr Psychiatry., 23, 466, 10.1016/j.jagp.2014.10.005 · DOI
  19. Kim, 2003, Subjective memory impairment, cognitive function and depression—a community study in older Koreans, Dement Geriatr Cogn Disorder., 15, 218, 10.1159/000068783 · DOI
  20. Fuhrer, 2003, Exploring sex differences in the relationship between depressive symptoms and dementia incidence: prospective results from the PAQUID study, J Am Geriatr Soc., 51, 1055, 10.1046/j.1532-5415.2003.51352.x · DOI
  21. Chen, 2011, Temporal relationship between depression and dementia Findings from a large community-based 15-year follow up study, Arch Gen Psychiatry., 68, 970, 10.1001/archgenpsychiatry.2011.86 · DOI
  22. Soares, 1997, The anatomy of mood disorders—review of structural neuroimaging studies, Biol Psychiatry., 41, 86, 10.1016/S0006-3223(96)00006-6 · DOI
  23. Greenwald, 1996, MRI signal hyperintensities in geriatric depression, Am J Psychiatry., 153, 1212, 10.1176/ajp.153.9.1212 · DOI
  24. Lesser, 1996, Cognition and white matter hyperintensities in older depressed patients, Am J Psychiatry., 153, 1280, 10.1176/ajp.153.10.1280 · DOI
  25. Jorm, 2000, Is depression a risk factor for dementia or cognitive decline?. A review, Gerontology., 46, 219, 10.1159/000022163 · DOI · Paper page
  26. Chen, 1999, The temporal relationship between depressive symptoms and dementia: a community-based prospective study, Arch Gen Psychiatry., 56, 261, 10.1001/archpsyc.56.3.261 · DOI · Paper page
  27. Yaffe, 1999, Depressive symptoms and cognitive decline in nondemented elderly women: a prospective study, Arch Gen Psychiatry., 56, 425, 10.1001/archpsyc.56.5.425 · DOI · Paper page
  28. Fuhrer, 1992, Depressive symptomatology and cognitive functioning: an epidemiological survey in an elderly community sample in France, Psychol Med., 22, 159, 10.1017/S0033291700032815 · DOI
  29. Olazarán, 2013, Cumulative effect of depression on dementia risk, Int J Alzheimers Dis., 10.1155/2013/457175 · DOI
  30. Brommelhoff, 2009, Depression as a risk factor or prodromal feature for dementia? Findings in a population-based sample of Swedish twins, Psychol Aging., 24, 373, 10.1037/a0015713 · DOI
  31. Saczynski, 2010, Depressive symptoms and risk of dementia: the Framingham Heart Study, Neurology., 75, 35, 10.1212/WNL.0b013e3181e62138 · DOI · Paper page
  32. Cooper, 1998, Previous psychiatric history as a risk factor for late-life dementia: a population-based case-control study, Age ageing., 27, 181, 10.1093/ageing/27.2.181 · DOI
  33. Chen, 2008, Severity of depression and risk for subsequent dementia: cohort studies in China and the UK, Br J Psychiatry., 193, 373, 10.1192/bjp.bp.107.044974 · DOI
  34. Vilalta-Franch, 2013, Depression subtypes and 5-year risk of dementia and Alzheimer disease in patients aged 70 years, Int J Geriatr Psychiatry., 28, 341, 10.1002/gps.3826 · DOI
  35. Martínez, 2008, Risk factors for dementia in the epidemiological study of Munguialde County (Basque Country-Spain), BMC Neurol., 8
  36. Steenland, 2012, Late-life depresion as a risk factor for mild cognitive impairment or Alzheimer's disease in 30 US Alzheimer's disease Centers, Int J Alzheimers Dis., 31, 265, 10.3233/JAD-2012-111922 · DOI
  37. Ownby, 2006, Depression and risk for Alzheimer disease: systematic review,meta-analysis, and meta regression analysis, Arch Gen Psychiatry., 63, 530, 10.1001/archpsyc.63.5.530 · DOI · Paper page
  38. Diniz, 2013, Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies, Br J Psychiatry., 202, 329, 10.1192/bjp.bp.112.118307 · DOI · Paper page
  39. Gao, 2013, Depression as a risk factor for dementia and mild cognitive impairment: a meta-analysis of longitudinal studies, Int J Geriatr Psychiatry., 28, 441, 10.1002/gps.3845 · DOI
  40. Butters, 2008, Pathways linking late-life depression to persistent cognitive impairment and dementia, Dialogues Clin Neurosci., 10, 345, 10.31887/DCNS.2008.10.3/mabutters · DOI
  41. Namekawa, 2013, Heterogeneity of elderly depression: increased risk of Alzheimer's disease and Aβ protein metabolism, Prog Neuropsychopharmacol Biol Psychiatry., 43, 203, 10.1016/j.pnpbp.2012.12.016 · DOI
  42. Mann, 1986, Neurotransmitter deficits in AD and in other dementing disorders, Hum Neurobiol., 5, 147
  43. Palmer, 1988, Possible neurotransmitter basis of behavioral changes in AD, Ann Neurol., 23, 616, 10.1002/ana.410230616 · DOI
  44. Whitehouse, 1987, Neurotransmitter receptor alterations in AD: a review, Alzheimer Dis Assoc Disord., 1, 9, 10.1097/00002093-198701000-00003 · DOI
  45. Chapman, 2006, Dementia and its implications for public health, Prev Chronic Dis., 3, A34

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Metadata

Authors
Deví Bastida, J., Puig Pomés, N., Jofre Font, S., & Fetscher Eickhoff, A.
Venue
Revista Española de Geriatría y Gerontología
Publisher
Elsevier BV
Published
2016-03
Volume
51
Issue
2
Pages
112-118
ISSN
0211-139X (ISSN-L)
OpenAlex
W2183492123
Cited by
19
References
3
Citations by year
2025: 2 · 2024: 3 · 2023: 6 · 2022: 1 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 2
FWCI
0.09
Type
journal article
Language
es
Open access
closed
Locations
  • Revista Española de Geriatría y Gerontología (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
  • Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Keywords
depression, dementia, Alzheimer's disease, dementia risk, depression as risk factor, dementia prevention, risk factors, odds ratio, hazard ratio, attributable fraction, meta-regression, publication bias, study quality assessment, cognitive screening
MeSH terms
Aged, Dementia, Depression, Depressive Disorder, Humans, Risk Factors

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