Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 14

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Intermittent fasting ameliorates di-(2-ethylhexyl) phthalate-induced precocious puberty in female rats: A study of the hypothalamic–pituitary–gonadal axis

Yu, Zhen, Zhan, Qiufeng, Chen, Ayun, Han, Junyong, Zheng, Yuanyuan, Gong, Yuqing, Lu, Rongmei, Zheng, Zeyu, Chen, Gang·2021·Reproductive Biology

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.repbio.2021.100513

Cites

6 of 6 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 6 references

Research works printed but not linked: 59

  1. Gao, 2018, Specific effects of prenatal DEHP exposure on neuroendocrine gene expression in the developing hypothalamus of male rats, Arch Toxicol, 92, 501, 10.1007/s00204-017-2049-z · DOI
  2. Johns, 2015, Urinary phthalate metabolites in relation to maternal serum thyroid and sex hormone levels during pregnancy: a longitudinal analysis, Reprod Biol Endocrinol, 13, 4, 10.1186/1477-7827-13-4 · DOI
  3. Xiu, 2020, DEHP degradation and dechlorination of polyvinyl chloride waste in subcritical water with alkali and ethanol: a comparative study, Chemosphere, 249, 10.1016/j.chemosphere.2020.126138 · DOI
  4. Wu, 2017, Phthalate levels and related factors in children aged 6-12 years, Environ Pollut, 220, 990, 10.1016/j.envpol.2016.11.049 · DOI
  5. Liu, 2018, Di-(2-ethylhexyl) phthalate induces precocious puberty in adolescent female rats, Iran J Basic Med Sci, 21, 848
  6. Yang, 2020, The dynamic assessment of toxicity and pathological process of DEHP in germ cells of male Sprague Dawley rats, Reprod Biol, 10.1016/j.repbio.2020.07.005 · DOI
  7. Xia, 2018, Phthalate exposure and childhood overweight and obesity: urinary metabolomic evidence, Environ Int, 121, 159, 10.1016/j.envint.2018.09.001 · DOI
  8. Parada, 2018, Urinary phthalate metabolite concentrations and breast Cancer incidence and survival following breast Cancer: the long island breast Cancer study project, Environ Health Perspect, 126, 47013, 10.1289/EHP2083 · DOI
  9. Kasper-Sonnenberg, 2017, Pre-pubertal exposure with phthalates and bisphenol A and pubertal development, PLoS One, 12, 10.1371/journal.pone.0187922 · DOI
  10. Frederiksen, 2012, High urinary phthalate concentration associated with delayed pubarche in girls, Int J Androl, 35, 216, 10.1111/j.1365-2605.2012.01260.x · DOI · Paper page
  11. Lai, 2017, Di (2-ethylhexyl) phthalate impairs steroidogenesis in ovarian follicular cells of prepuberal mice, Arch Toxicol, 91, 1279, 10.1007/s00204-016-1790-z · DOI
  12. Ma, 2006, Exposure of prepubertal female rats to inhaled di(2-ethylhexyl)phthalate affects the onset of puberty and postpubertal reproductive functions, Toxicol Sci, 93, 164, 10.1093/toxsci/kfl036 · DOI
  13. Svechnikova, 2007, The influence of di-(2-ethylhexyl) phthalate on steroidogenesis by the ovarian granulosa cells of immature female rats, J Endocrinol, 194, 603, 10.1677/JOE-07-0238 · DOI
  14. Moyer, 2012, Reproductive effects in F1 adult females exposed in utero to moderate to high doses of mono-2-ethylhexylphthalate (MEHP), Reprod Toxicol, 34, 43, 10.1016/j.reprotox.2012.02.006 · DOI
  15. Patino-Garcia, 2018, Reproductive alterations in chronically exposed female mice to environmentally relevant doses of a mixture of phthalates and alkylphenols, Endocrinology, 159, 1050, 10.1210/en.2017-00614 · DOI
  16. Kinoshita, 2005, Involvement of central metastin in the regulation of preovulatory luteinizing hormone surge and estrous cyclicity in female rats, Endocrinology, 146, 4431, 10.1210/en.2005-0195 · DOI · Paper page
  17. Asai, 2000, Structural essentials of xenoestrogen dialkyl phthalates to bind to the estrogen receptors, Toxicol Lett, 118, 1, 10.1016/S0378-4274(00)00253-8 · DOI
  18. Shanle, 2011, Endocrine disrupting chemicals targeting estrogen receptor signaling: identification and mechanisms of action, Chem Res Toxicol, 24, 6, 10.1021/tx100231n · DOI · Paper page
  19. Engel, 2017, Agonistic and antagonistic effects of phthalates and their urinary metabolites on the steroid hormone receptors ERalpha, ERbeta, and AR, Toxicol Lett, 277, 54, 10.1016/j.toxlet.2017.05.028 · DOI
  20. Hlisnikova, 2020, Effects and mechanisms of phthalates’ action on reproductive processes and reproductive health: a literature review, Int J Environ Res Public Health, 17, 10.3390/ijerph17186811 · DOI · Paper page
  21. Shao, 2019, The interference of DEHP in precocious puberty of females mediated by the hypothalamic IGF-1/PI3K/Akt/mTOR signaling pathway, Ecotoxicol Environ Saf, 181, 362, 10.1016/j.ecoenv.2019.06.017 · DOI
  22. Yu, 2020, Opposite effects of high- and low-dose di-(2-ethylhexyl) phthalate (DEHP) exposure on puberty onset, oestrous cycle regularity and hypothalamic kisspeptin expression in female rats, Reprod Fertil Dev, 32, 610, 10.1071/RD19024 · DOI
  23. Fang, 2000, Quantitative comparisons of in vitro assays for estrogenic activities, Environ Health Perspect, 108, 723, 10.1289/ehp.00108723 · DOI
  24. Kuohung, 2006, GPR54 and KiSS-1: role in the regulation of puberty and reproduction, Rev Endocr Metab Disord, 7, 257, 10.1007/s11154-006-9020-2 · DOI
  25. Castellano, 2013, Metabolic regulation of kisspeptin, Adv Exp Med Biol, 784, 363, 10.1007/978-1-4614-6199-9_17 · DOI · Paper page
  26. Polkowska, 2015, The effect of short fasting on the hypothalamic neuronal system of kisspeptin in peripubertal female lambs, Anim Reprod Sci, 159, 184, 10.1016/j.anireprosci.2015.06.016 · DOI
  27. Wahab, 2011, Decrease in hypothalamic Kiss1 and Kiss1r expression: a potential mechanism for fasting-induced suppression of the HPG axis in the adult male rhesus monkey (Macaca mulatta), Horm Metab Res, 43, 81, 10.1055/s-0030-1269852 · DOI · Paper page
  28. Fernandez-Fernandez, 2006, Novel signals for the integration of energy balance and reproduction, Mol Cell Endocrinol, 254-255, 127, 10.1016/j.mce.2006.04.026 · DOI · Paper page
  29. Brown, 2008, KiSS-1 mRNA in adipose tissue is regulated by sex hormones and food intake, Mol Cell Endocrinol, 281, 64, 10.1016/j.mce.2007.10.011 · DOI
  30. Wade, 2004, Neuroendocrinology of nutritional infertility, Am J Physiol Regul Integr Comp Physiol, 287, R1277, 10.1152/ajpregu.00475.2004 · DOI
  31. Patterson, 2017, Metabolic effects of intermittent fasting, Annu Rev Nutr, 37, 371, 10.1146/annurev-nutr-071816-064634 · DOI · Paper page
  32. Varady, 2007, Alternate-day fasting and chronic disease prevention: a review of human and animal trials, Am J Clin Nutr, 86, 7, 10.1093/ajcn/86.1.7 · DOI
  33. Gotthardt, 2016, Intermittent fasting promotes fat loss with lean mass retention, increased hypothalamic norepinephrine content, and increased neuropeptide y gene expression in diet-induced obese male mice, Endocrinology, 157, 679, 10.1210/en.2015-1622 · DOI
  34. Joslin, 2017, Obese mice on a high-fat alternate-day fasting regimen lose weight and improve glucose tolerance, J Anim Physiol Anim Nutr (Berl), 101, 1036, 10.1111/jpn.12546 · DOI
  35. Yang, 2016, Alternate-day fasting protects the livers of mice against high-fat diet-induced inflammation associated with the suppression of Toll-like receptor 4/nuclear factor kappaB signaling, Nutr Res, 36, 586, 10.1016/j.nutres.2016.02.001 · DOI
  36. Yang, 2016, The interaction of fasting, caloric restriction, and diet-induced obesity with 17beta-estradiol on the expression of KNDy neuropeptides and their receptors in the female mouse, Mol Cell Endocrinol, 437, 35, 10.1016/j.mce.2016.08.008 · DOI
  37. Castellano, 2016, Metabolic control of female puberty: potential therapeutic targets, Expert Opin Ther Targets, 20, 1181, 10.1080/14728222.2016.1212015 · DOI
  38. Landry, 2013, Implications of leptin in neuroendocrine regulation of male reproduction, Reprod Biol, 13, 1, 10.1016/j.repbio.2012.12.001 · DOI
  39. Ronnekleiv, 2019, Arcuate kisspeptin neurons coordinate reproductive activities with metabolism, Semin Reprod Med, 37, 131, 10.1055/s-0039-3400251 · DOI
  40. Louis, 2011, Molecular mapping of the neural pathways linking leptin to the neuroendocrine reproductive axis, Endocrinology, 152, 2302, 10.1210/en.2011-0096 · DOI
  41. Smith, 2006, KiSS-1 neurones are direct targets for leptin in the ob/ob mouse, J Neuroendocrinol, 18, 298, 10.1111/j.1365-2826.2006.01417.x · DOI · Paper page
  42. Cardoso, 2010, Reproductive axis response to repeated lipopolysaccharide administration in peripubertal female rats, J Physiol Biochem, 66, 237, 10.1007/s13105-010-0030-x · DOI
  43. Hu, 2015, Relative importance of the arcuate and anteroventral periventricular kisspeptin neurons in control of puberty and reproductive function in female rats, Endocrinology, 156, 2619, 10.1210/en.2014-1655 · DOI
  44. Marraudino, 2017, Kisspeptin innervation of the hypothalamic paraventricular nucleus: sexual dimorphism and effect of estrous cycle in female mice, J Anat, 230, 775, 10.1111/joa.12603 · DOI
  45. Han, 2017, Intracerebroventricular injection of RFRP-3 delays puberty onset and stimulates growth hormone secretion in female rats, Reprod Biol Endocrinol, 15, 35, 10.1186/s12958-017-0254-5 · DOI
  46. Cravo, 2013, Leptin signaling in Kiss1 neurons arises after pubertal development, PLoS One, 8, 10.1371/journal.pone.0058698 · DOI
  47. Venturelli, 2015, Effects of exposure to Di-(2-ethylhexyl) phthalate (DEHP) during lactation and puberty on sexual maturation and glycemic homeostasis in males rats, Clin Nutr ESPEN, 10, e5, 10.1016/j.clnme.2014.10.002 · DOI
  48. Wassenaar, 2017, Systematic review and meta-analysis of early life exposure to di(2-ethylhexyl) phthalate and obesity related outcomes in rodents, Chemosphere, 188, 174, 10.1016/j.chemosphere.2017.08.165 · DOI
  49. Xu, 2018, Di-(2-ethylhexyl)-phthalate induces glucose metabolic disorder in adolescent rats, Environ Sci Pollut Res Int, 25, 3596, 10.1007/s11356-017-0738-z · DOI
  50. Kennedy, 1963, Body weight and food intake as initiating factors for puberty in the rat, J Physiol, 166, 408, 10.1113/jphysiol.1963.sp007112 · DOI · Paper page
  51. Li, 2012, High-fat diet increases LH pulse frequency and kisspeptin-neurokinin B expression in puberty-advanced female rats, Endocrinology, 153, 4422, 10.1210/en.2012-1223 · DOI
  52. Trevisan, 2018, Kisspeptin/GPR54 System: What Do We Know About Its Role in Human Reproduction?, Cell Physiol Biochem, 49, 1259, 10.1159/000493406 · DOI
  53. Hussain, 2015, There is kisspeptin - and then there is Kisspeptin, Trends Endocrinol Metab, 26, 564, 10.1016/j.tem.2015.07.008 · DOI
  54. Yang, 2016, Prepubertal exposure to an oestrogenic mycotoxin zearalenone induces central precocious puberty in immature female rats through the mechanism of premature activation of hypothalamic kisspeptin-GPR54 signaling, Mol Cell Endocrinol, 437, 62, 10.1016/j.mce.2016.08.012 · DOI
  55. Burger, 2011, Endocrine, 39, 212, 10.1007/s12020-011-9440-y · DOI
  56. Varady, 2007, Effects of modified alternate-day fasting regimens on adipocyte size, triglyceride metabolism, and plasma adiponectin levels in mice, J Lipid Res, 48, 2212, 10.1194/jlr.M700223-JLR200 · DOI
  57. Backholer, 2010, Kisspeptin cells in the ewe brain respond to leptin and communicate with neuropeptide Y and proopiomelanocortin cells, Endocrinology, 151, 2233, 10.1210/en.2009-1190 · DOI · Paper page
  58. Qiu, 2011, Guinea pig kisspeptin neurons are depolarized by leptin via activation of TRPC channels, Endocrinology, 152, 1503, 10.1210/en.2010-1285 · DOI
  59. Qiu, 2011, Guinea pig kisspeptin neurons are depolarized by leptin via activation of TRPC channels, Endocrinology, 152, 1503, 10.1210/en.2010-1285 · DOI

Metadata

Authors
Yu, Z., Zhan, Q., Chen, A., Han, J., Zheng, Y., Gong, Y., Lu, R., Zheng, Z., & Chen, G.
Venue
Reproductive Biology
Publisher
Elsevier BV
Published
2021-09
Volume
21
Issue
3
Pages
100513
ISSN
1642-431X
Cited by
14
References
6
Language
en
Licence
  • www.elsevier.com/tdm/userlicense/1.0/ (tdm)
  • www.elsevier.com/legal/tdmrep-license (tdm)
Funders
  • Fujian Provincial Department of Science and Technology
  • Fujian Provincial Hospital (2017 GL-003)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Intermittent fasting ameliorates di-(2-ethylhexyl) phthalate-induced precocious puberty in female rats: A study of the hypothalamic–pituitary–gonadal axis. https://app.cochat.ai/papers/10.1016/j.repbio.2021.100513
The paper
Yu, Z., Zhan, Q., Chen, A., Han, J., Zheng, Y., Gong, Y., Lu, R., Zheng, Z., & Chen, G. (2021). Intermittent fasting ameliorates di-(2-ethylhexyl) phthalate-induced precocious puberty in female rats: A study of the hypothalamic–pituitary–gonadal axis. Reproductive Biology. https://doi.org/10.1016/j.repbio.2021.100513

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.