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Cited by 269

The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.

The prevalence and significance of abnormal vital signs prior to in-hospital cardiac arrest

Open access
Andersen, Lars W., Kim, Won Young, Chase, Maureen, Berg, Katherine--> M., Mortensen, Sharri J., Moskowitz, Ari, Novack, Victor, Cocchi, Michael N., Donnino, Michael W.·2016·Resuscitation
DOI 10.1016/j.resuscitation.2015.08.016
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Abstract

Background Patients suffering in-hospital cardiac arrest often show signs of physiological deterioration before the event. The purpose of this study was to determine the prevalence of abnormal vital signs 1–4 hours before cardiac arrest, and to evaluate the association between these vital sign abnormalities and inhospital mortality. Methods We included adults from the Get With the Guidelines® - Resuscitation registry with an in-hospital cardiac arrest. We used two a priori definitions for vital signs: abnormal (heart rate (HR) ≤ 60 or ≥ 100 min−1, respiratory rate (RR) ≤ 10 or > 20 min−1 and systolic blood pressure (SBP) ≤ 90 mm Hg) and severely abnormal (HR ≤ 50 or ≥ 130 min−1, RR ≤ 8 or ≥ 30 min−1 and SBP ≤80 mm Hg). We evaluated the association between the number of abnormal vital signs and in-hospital mortality using a multivariable logistic regression model. Results 7,851 patients were included. Individual vital signs were associated with in-hospital mortality. The majority of patients (59.4%) had at least one abnormal vital sign 1–4 hours before the arrest and 13.4% had at least one severely abnormal sign. We found a step-wise increase in mortality with increasing number of abnormal vital signs within the abnormal (odds ratio (OR) 1.53 (CI: 1.42 – 1.64) and severely abnormal groups (OR 1.62 [CI: 1.38 – 1.90]). This remained in multivariable analysis (abnormal: OR 1.38 [CI: 1.28 – 1.48], and severely abnormal: OR 1.40 [CI: 1.18 – 1.65]). Conclusion Abnormal vital signs are prevalent 1–4 hours before in-hospital cardiac arrest on hospital wards. Inhospital mortality increases with increasing number of pre-arrest abnormal vital signs as well as increased severity of vital sign derangements.

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Metadata

Authors
Andersen, L. W., Kim, W. Y., Chase, M., Berg, K.->. M., Mortensen, S. J., Moskowitz, A., Novack, V., Cocchi, M. N., & Donnino, M. W.
Venue
Resuscitation
Publisher
Elsevier BV
Published
2016-01
Volume
98
Pages
112-117
ISSN
0300-9572 (ISSN-L)
DOI
10.1016/j.resuscitation.2015.08.016
OpenAlex
W1472453757
Cited by
269
References
31
FWCI
6.69
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: The prevalence and significance of abnormal vital signs prior to in-hospital cardiac arrest. https://app.cochat.ai/papers/10.1016/j.resuscitation.2015.08.016
The paper
Andersen, L. W., Kim, W. Y., Chase, M., Berg, K.->. M., Mortensen, S. J., Moskowitz, A., Novack, V., Cocchi, M. N., & Donnino, M. W. (2016). The prevalence and significance of abnormal vital signs prior to in-hospital cardiac arrest. Resuscitation. https://doi.org/10.1016/j.resuscitation.2015.08.016

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.