Soluble guanylate cyclase

Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations

Arnold, W. P., Mittal, C. K., Katsuki, S., & Murad, F. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.8.3203 · Cited by 1,459 · see citing works

Crystal Structure of the Catalytic Domains of Adenylyl Cyclase in a Complex with G sα ·GTPγS

Tesmer, J. J. G., Sunahara, R. K., Gilman, A. G., & Sprang, S. R. (1997) · Science · doi:10.1126/science.278.5345.1907 · Cited by 796 · see citing works

A molecular basis for nitric oxide sensing by soluble guanylate cyclase

Zhao, Y., Brandish, P. E., Ballou, D. P., & Marletta, M. A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.26.14753 · Cited by 323 · see citing works

Myoglobin discriminates between O2, NO, and CO by electrostatic interactions with the bound ligand

Olson, J. S., & Phillips, G. N. (1997) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s007750050169 · Cited by 288 · see citing works

Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases

Pellicena, P., Karow, D. S., Boon, E. M., Marletta, M. A., & Kuriyan, J. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0405188101 · Cited by 271 · see citing works

NO activation of guanylyl cyclase

Russwurm, M., & Koesling, D. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600422 · Cited by 222 · see citing works

Femtomolar Sensitivity of a NO Sensor from Clostridium botulinum

Nioche, P., Berka, V., Vipond, J., Minton, N. P., Tsai, A., & Raman, C. S. (2004) · Science · doi:10.1126/science.1103596 · Cited by 189 · see citing works

A molecular basis for NO selectivity in soluble guanylate cyclase

Boon, E. M., Huang, S. H., & Marletta, M. A. (2005) · Nature Chemical Biology · doi:10.1038/nchembio704 · Cited by 188 · see citing works

Spectroscopic Characterization of the Soluble Guanylate Cyclase-like Heme Domains from Vibrio cholerae and Thermoanaerobacter tengcongensis

Karow, D. S., Pan, D., Tran, R., Pellicena, P., Presley, A. D., Mathies, R. A., & Marletta, M. A. (2004) · Biochemistry · doi:10.1021/bi049374l · Cited by 184 · see citing works

Unprecedented proximal binding of nitric oxide to heme: implications for guanylate cyclase

Lawson, D. M., Stevenson, C. E. M., Andrew, C. R., & Eady, R. R. (2000) · The EMBO Journal · doi:10.1093/emboj/19.21.5661 · Cited by 168 · see citing works

The Synthetic and Structural Chemistry of Heme Derivatives with Nitric Oxide Ligands

Scheidt, W. R., & Ellison, M. K. (1999) · Accounts of Chemical Research · doi:10.1021/ar9700116 · Cited by 168 · see citing works

Purifieation of a Soluble, Sodium‐Nitroprusside‐Stimulated Guanylate Cyclase from Bovine Lung

Gerzer, R., Hofmann, F. B., & Schultz, G. (1981) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1981.tb05361.x · Cited by 147 · see citing works

Tonic and acute nitric oxide signaling through soluble guanylate cyclase is mediated by nonheme nitric oxide, ATP, and GTP

Cary, S. P., Winger, J. A., & Marletta, M. A. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506289102 · Cited by 145 · see citing works

On the activation of soluble guanylyl cyclase by nitric oxide

Bellamy, T. C., Wood, J., & Garthwaite, J. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.012368499 · Cited by 141 · see citing works

Ligand specificity of H-NOX domains: from sGC to bacterial NO sensors

Boon, E. M., & Marletta, M. A. (2005) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2004.12.016 · Cited by 113 · see citing works

Purification and properties of heme-deficient hepatic soluble guanylate cyclase: Effects of heme and other factors on enzyme activation by NO, NO-heme, and protoporphyrin IX

Ohlstein, E. H., Wood, K. S., & Ignarro, L. J. (1982) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(82)90335-6 · Cited by 106 · see citing works

Ligand Selectivity of Soluble Guanylyl Cyclase

Martin, E., Berka, V., Bogatenkova, E., Murad, F., & Tsai, A.-L. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m601078200 · Cited by 97 · see citing works

Ligand discrimination in soluble guanylate cyclase and the H-NOX family of heme sensor proteins

Boon, E. M., & Marletta, M. A. (2005) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2005.08.015 · Cited by 96 · see citing works

Regeneration of the Ferrous Heme of Soluble Guanylate Cyclase from the Nitric Oxide Complex: Acceleration by Thiols and Oxyhemoglobin

Brandish, P. E., Buechler, W. A., & Marletta, M. A. (1998) · Biochemistry · doi:10.1021/bi9814989 · Cited by 95 · see citing works

Expression and Characterization of the Catalytic Domains of Soluble Guanylate Cyclase:  Interaction with the Heme Domain

Winger, J. A., & Marletta, M. A. (2005) · Biochemistry · doi:10.1021/bi047601d · Cited by 87 · see citing works

Nitric oxide activation of guanylyl cyclase in cells revisited

Roy, B., & Garthwaite, J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602544103 · Cited by 85 · see citing works

Studying the Structure and Regulation of Soluble Guanylyl Cyclase

Koesling, D. (1999) · Methods · doi:10.1006/meth.1999.0891 · Cited by 84 · see citing works

Characterization of Functional Heme Domains from Soluble Guanylate Cyclase

Karow, D. S., Pan, D., Davis, J. H., Behrends, S., Mathies, R. A., & Marletta, M. A. (2005) · Biochemistry · doi:10.1021/bi051601b · Cited by 78 · see citing works

Kinetics and Equilibria of Soluble Guanylate Cyclase Ligation by CO: Effect of YC-1

Kharitonov, V. G., Sharma, V. S., Magde, D., & Koesling, D. (1999) · Biochemistry · doi:10.1021/bi990277f · Cited by 75 · see citing works

Nitric Oxide Interaction with Cytochromec‘ and Its Relevance to Guanylate Cyclase. Why Does the Iron Histidine Bond Break?

Marti, M. A., Capece, L., Crespo, A., Doctorovich, F. A., & Estrin, D. A. (2005) · Journal of the American Chemical Society · doi:10.1021/ja042870c · Cited by 68 · see citing works

The separation of the heme and apoheme forms of soluble guanylate cyclase

Gerzer, R., Radany, E. W., & Garbers, D. L. (1982) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(82)90883-x · Cited by 57 · see citing works

Interactions of soluble guanylate cyclase with diatomics as probed by resonance Raman spectroscopy

Pal, B., & Kitagawa, T. (2004) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2004.09.027 · Cited by 35 · see citing works

Identification of residues crucially involved in soluble guanylate cyclase activation

Rothkegel, C., Schmidt, P. M., Stoll, F., Schröder, H., Schmidt, H. H. H. W., & Stasch, J. (2006) · FEBS Letters · doi:10.1016/j.febslet.2006.06.079 · Cited by 33 · see citing works

Human Soluble Guanylate Cyclase: Functional Expression, Purification and Structural Characterization

Kosarikov, D. N., Young, P., Uversky, V. N., & Gerber, N. C. (2001) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.2001.2284 · Cited by 18 · see citing works

Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways

Mishanina, T. V., Libiad, M., & Banerjee, R. V. (2015) · Nature Chemical Biology · doi:10.1038/nchembio.1834 · Cited by 612 · see citing works

Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation

Tejero, J., Shiva, S., & Gladwin, M. T. (2019) · Physiological Reviews · doi:10.1152/physrev.00036.2017 · Cited by 541 · see citing works

Understanding nitrate assimilation and its regulation in microalgae

Sanz‐Luque, E., Chamizo‐Ampudia, A., Llamas, Á., Galván, A., & Fernández, E. M. (2015) · Frontiers in Plant Science · doi:10.3389/fpls.2015.00899 · Cited by 453 · see citing works

Interactions of Multiple Gas-Transducing Systems: Hallmarks and Uncertainties of CO, NO, and H 2 S Gas Biology

Kajimura, M., Fukuda, R., Bateman, R. M., Yamamoto, T., & Suematsu, M. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2657 · Cited by 265 · see citing works

Novel lead structures and activation mechanisms for CO ‐releasing molecules ( CORMs )

Schatzschneider, U. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12688 · Cited by 251 · see citing works

Designing Artificial Metalloenzymes by Tuning of the Environment beyond the Primary Coordination Sphere

Stappen, C. V., Deng, Y., Liu, Y., Heidari, H., Wang, J., Zhou, Y., Ledray, A. P., & Lu, Y. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.2c00106 · Cited by 174 · see citing works

The effects of nitric oxide on the immune system during Trypanosoma cruzi infection

Gutierrez, F. R. S., Mineo, T. W. P., Pavanelli, W. R., Guedes, P. M. D. M., & Silva, J. S. (2009) · Memórias do Instituto Oswaldo Cruz · doi:10.1590/s0074-02762009000900030 · Cited by 151 · see citing works

Carbon dioxide-sensing in organisms and its implications for human disease

Cummins, E. P., Selfridge, A. C., Sporn, P. H. S., Sznajder, J. I., & Taylor, C. T. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1470-6 · Cited by 127 · see citing works

Iron-Based Redox Switches in Biology

Outten, F. W., & Theil, E. C. (2008) · Antioxidants and Redox Signaling · doi:10.1089/ars.2008.2296 · Cited by 123 · see citing works

The Diversity of Microbial Responses to Nitric Oxide and Agents of Nitrosative Stress

Bowman, L. A. H., McLean, S., Poole, R. K., & Fukuto, J. M. (2011) · Advances in microbial physiology/Advances in Microbial Physiology · doi:10.1016/b978-0-12-387661-4.00006-9 · Cited by 117 · see citing works

A comparison of the chemistry associated with the biological signaling and actions of nitroxyl (HNO) and nitric oxide (NO)

Fukuto, J. M., Cisneros, C. J., & Kinkade, R. L. (2012) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2012.08.027 · Cited by 118 · see citing works

The Effects of Nitroxyl (HNO) on Soluble Guanylate Cyclase Activity

Miller, T. W., Cherney, M. M., Lee, A. J., Francoleon, N. E., Farmer, P. J., King, S. B., Hobbs, A. J., Miranda, K. M., Burstyn, J. N., & Fukuto, J. M. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.014282 · Cited by 99 · see citing works

Structural insights into the role of iron–histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins

Herzik, M. A., Jonnalagadda, R., Kuriyan, J., & Marletta, M. A. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1416936111 · Cited by 95 · see citing works

Nitroxyl (azanone) trapping by metalloporphyrins

Doctorovich, F. A., Bikiel, D. E., Pellegrino, J., Suárez, S., Larsen, A., & Marti, M. A. (2011) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2011.04.012 · Cited by 93 · see citing works

Crystal Structures of the Catalytic Domain of Human Soluble Guanylate Cyclase

Allerston, C. K., von Delft, F., & Gileadi, O. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057644 · Cited by 79 · see citing works

Transcriptional Responses of Olive Flounder (Paralichthys olivaceus) to Low Temperature

Hu, J., You, F., Wang, Q., Shenda, W., Liu, H., Wang, L., Zhang, P., & Tan, X. (2014) · PLoS ONE · doi:10.1371/journal.pone.0108582 · Cited by 76 · see citing works

Mechanism of Binding of NO to Soluble Guanylyl Cyclase: Implication for the Second NO Binding to the Heme Proximal Site

Martin, E., Berka, V., Sharina, I. G., & Tsai, A.-L. (2012) · Biochemistry · doi:10.1021/bi300105s · Cited by 76 · see citing works

A structural basis for H-NOX signaling in Shewanella oneidensis by trapping a histidine kinase inhibitory conformation

Erbil, W. K., Price, M. S., Wemmer, D. E., & Marletta, M. A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911645106 · Cited by 73 · see citing works

S-Nitrosylation-induced Conformational Change in Blackfin Tuna Myoglobin

Schreiter, E. R., Rodríguez, M. M., Weichsel, A., Montfort, W. R., & Bonaventura, J. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m701363200 · Cited by 63 · see citing works

Regulatory FeII/III Heme: The Reconstruction of a Molecule's Biography

Kühl, T., & Imhof, D. (2014) · ChemBioChem · doi:10.1002/cbic.201402218 · Cited by 61 · see citing works

Carbon monoxide is not always a poison gas for human organism: Physiological and pharmacological features of CO

Olas, B. (2014) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2014.08.005 · Cited by 60 · see citing works

How Do Heme-Protein Sensors Exclude Oxygen? Lessons Learned from Cytochrome c′, Nostoc puntiforme Heme Nitric Oxide/Oxygen-Binding Domain, and Soluble Guanylyl Cyclase

Tsai, A.-L., Martin, E., Berka, V., & Olson, J. S. (2012) · Antioxidants and Redox Signaling · doi:10.1089/ars.2012.4564 · Cited by 60 · see citing works

Oxidative heme protein-mediated nitroxyl (HNO) generation

Reisz, J. A., Bechtold, E., & King, S. B. (2010) · Dalton Transactions · doi:10.1039/c000980f · Cited by 59 · see citing works

Oxidation and Loss of Heme in Soluble Guanylyl Cyclase from Manduca sexta

Fritz, B. G., Hu, X., Brailey, J. L., Berry, R. E., Walker, F. A., & Montfort, W. R. (2011) · Biochemistry · doi:10.1021/bi200794c · Cited by 58 · see citing works

Interplay between Obesity-Induced Inflammation and cGMP Signaling in White Adipose Tissue

Sanyal, A., Naumann, J., Hoffmann, L. S., Chabowska-Kita, A., Ehrlund, A., Schlitzer, A., Arner, P., Blüher, M., & Pfeifer, A. (2017) · Cell Reports · doi:10.1016/j.celrep.2016.12.028 · Cited by 55 · see citing works

Acyloxy Nitroso Compounds as Nitroxyl (HNO) Donors: Kinetics, Reactions with Thiols, and Vasodilation Properties

Shoman, M. E., DuMond, J. F., Isbell, T. S., Crawford, J. H., Brandon, A. P., Honovar, J., Vitturi, D. A., White, C. R., Patel, R. P., & King, S. B. (2011) · Journal of Medicinal Chemistry · doi:10.1021/jm101432z · Cited by 54 · see citing works

Regulation of Endothelial Nitric Oxide Synthase Activity by Protein-Protein Interaction

Su, Y. (2014) · Current Pharmaceutical Design · doi:10.2174/13816128113196660752 · Cited by 54 · see citing works

Dynamical Characterization of the Heme NO Oxygen Binding (HNOX) Domain. Insight into Soluble Guanylate Cyclase Allosteric Transition

Capece, L., Estrin, D. A., & Marti, M. A. (2008) · Biochemistry · doi:10.1021/bi800682k · Cited by 52 · see citing works

Nitric oxide production and signalling in algae

Astier, J., Rossi, J., Chatelain, P., Klinguer, A., Besson‐Bard, A., Rosnoblet, C., Jeandroz, S., Nicolas-Francès, V., & Wendehenne, D. (2020) · Journal of Experimental Botany · doi:10.1093/jxb/eraa421 · Cited by 50 · see citing works

Heme-Copper Assembly Mediated Reductive Coupling of Nitrogen Monoxide (·NO)

Wang, J., Schopfer, M. P., Sarjeant, A. A. N., & Karlin, K. D. (2008) · Journal of the American Chemical Society · doi:10.1021/ja8084324 · Cited by 50 · see citing works

Photolability of NO in designed metal nitrosyls with carboxamido-N donors: a theoretical attempt to unravel the mechanism

Fry, N. L., & Mascharak, P. K. (2012) · Dalton Transactions · doi:10.1039/c2dt12470j · Cited by 48 · see citing works

Thrombospondin-1 and Angiotensin II Inhibit Soluble Guanylyl Cyclase through an Increase in Intracellular Calcium Concentration

Ramanathan, S., Mazzalupo, S., Boitano, S. A., & Montfort, W. R. (2011) · Biochemistry · doi:10.1021/bi201060c · Cited by 47 · see citing works

ADMA injures the glomerular filtration barrier: role of nitric oxide and superoxide

Sharma, M., Zhou, Z., Miura, H., Papapetropoulos, A., McCarthy, E. T., Sharma, R., Savin, V. J., & Lianos, E. A. (2009) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.90369.2008 · Cited by 46 · see citing works

Allostery in Recombinant Soluble Guanylyl Cyclase from Manduca sexta

Hu, X., Murata, L. B., Weichsel, A., Brailey, J. L., Roberts, S. A., Nighorn, A. J., & Montfort, W. R. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m801501200 · Cited by 45 · see citing works

Nitric oxide pathology and therapeutics in sickle cell disease

Kim‐Shapiro, D. B., & Gladwin, M. T. (2018) · Clinical Hemorheology and Microcirculation · doi:10.3233/ch-189009 · Cited by 47 · see citing works

Two decades of new concepts in nitric oxide signaling: From the discovery of a gas messenger to the mediation of nonenzymatic posttranslational modifications

Martı́nez-Ruiz, A., & Lamas, S. (2008) · IUBMB Life · doi:10.1002/iub.144 · Cited by 45 · see citing works

Aged garlic extract inhibits human platelet aggregation by altering intracellular signaling and platelet shape change

Rahman, K., Lowe, G. M., & Smith, S. (2016) · The Journal of Nutrition · doi:10.3945/jn.114.202408 · Cited by 43 · see citing works

Nitric Oxide-Releasing Platforms for Treating Cardiovascular Disease

He, M., Wang, D., Xu, Y., Jiang, F., Zheng, J., Feng, Y., Cao, J.-M., & Zhou, X. H. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14071345 · Cited by 44 · see citing works

Role of cAMP and cGMP Signaling in Brown Fat

Reverte-Salisa, L., Sanyal, A., & Pfeifer, A. (2018) · Handbook of experimental pharmacology · doi:10.1007/164_2018_117 · Cited by 42 · see citing works

Activation Parameters for Heme−NO Binding in Alcaligenes xylosoxidans Cytochrome c′: The Putative Dinitrosyl Intermediate Forms via a Dissociative Mechanism

Pixton, D. A., Petersen, C. A., Franke, A., van Eldik, R., Garton, E. M., & Andrew, C. R. (2009) · Journal of the American Chemical Society · doi:10.1021/ja809587q · Cited by 42 · see citing works

Nitric oxide signaling in the brain: translation of dynamics into respiration control and neurovascular coupling

Laranjinha, J. A. N., Santos, R. M., Lourenço, C. F., Ledo, A., & Barbosa, R. M. (2012) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2012.06582.x · Cited by 41 · see citing works

Structural and Functional Evidence Indicates Selective Oxygen Signaling in Caldanaerobacter subterraneus H-NOX

Hespen, C. W., Bruegger, J. J., Phillips‐Piro, C. M., & Marletta, M. A. (2016) · ACS Chemical Biology · doi:10.1021/acschembio.6b00431 · Cited by 41 · see citing works

Interstitial cells of Cajal contain signalling molecules for transduction of nitrergic stimulation in guinea pig caecum

Iino, S., Horiguchi, K., Nojyo, Y., Ward, S. M., & Sanders, K. M. (2009) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2008.01236.x · Cited by 40 · see citing works

High Intraocular Pressure Following Anti-Vascular Endothelial Growth Factor Therapy: Proposed Pathophysiology due to Altered Nitric Oxide Metabolism

Ricca, A. M., Morshedi, R. G., & Wirostko, B. M. (2014) · Journal of Ocular Pharmacology and Therapeutics · doi:10.1089/jop.2014.0062 · Cited by 39 · see citing works

Cardiac Hypoxia Tolerance in Fish: From Functional Responses to Cell Signals

Cerra, M. C., Filice, M., Caferro, A., Mazza, R., Gattuso, A., & Imbrogno, S. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24021460 · Cited by 38 · see citing works

Heme and Hemoproteins

Munro, A. W., Girvan, H. M., McLean, K. J., Cheesman, M. R., & Leys, D. (2009) · Springer eBooks · doi:10.1007/978-0-387-78518-9_10 · Cited by 36 · see citing works

Nitric oxide/cGMP signalling inducesEscherichia coliK1 receptor expression and modulates the permeability in human brain endothelial cell monolayers during invasion

Mittal, R., & Prasadarao, N. V. (2009) · Cellular Microbiology · doi:10.1111/j.1462-5822.2009.01379.x · Cited by 34 · see citing works

Structural basis for oxygen sensing and signal transduction of the heme-based sensor protein Aer2 from Pseudomonas aeruginosa

Sawai, H., Sugimoto, H., Shiro, Y., Ishikawa, H., Mizutani, Y., & Aono, S. (2012) · Chemical Communications · doi:10.1039/c2cc32549g · Cited by 34 · see citing works

Structural and thermodynamic consequences of b heme binding for monomeric apoglobins and other apoproteins

Landfried, D. A., Vuletich, D. A., Pond, M. P., & Lecomte, J. T. J. (2007) · Gene · doi:10.1016/j.gene.2007.02.046 · Cited by 32 · see citing works

The bioactivity of neuronal-derived nitric oxide in aging and neurodegeneration: Switching signaling to degeneration

Ledo, A., Lourenço, C. F., Cadenas, E., Barbosa, R. M., & Laranjinha, J. A. N. (2020) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2020.11.005 · Cited by 30 · see citing works

Antagonism of soluble guanylyl cyclase attenuates cutaneous vasodilation during whole body heat stress and local warming in humans

Kellogg, D. L., Zhao, J. L., Wu, Y., & Johnson, J. M. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00702.2010 · Cited by 29 · see citing works

Molecular biosensor based on a coordinated iron complex

Salazar-Salinas, K., Jauregui, L. A., Kubli‐Garfias, C., & Seminario, J. M. (2009) · The Journal of Chemical Physics · doi:10.1063/1.3070235 · Cited by 29 · see citing works

Butyl Isocyanide as a Probe of the Activation Mechanism of Soluble Guanylate Cyclase

Derbyshire, E. R., & Marletta, M. A. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m705557200 · Cited by 29 · see citing works

Recent Progress in Photoinduced NO Delivery With Designed Ruthenium Nitrosyl Complexes

deBoer, T. R., & Mascharak, P. K. (2014) · Advances in inorganic chemistry · doi:10.1016/bs.adioch.2014.11.002 · Cited by 28 · see citing works

The evolution of small molecule enzyme activators

Dow, L. F., Case, A. M., Paustian, M. P., Pinkerton, B. R., Simeon, P., & Trippier, P. C. (2023) · RSC Medicinal Chemistry · doi:10.1039/d3md00399j · Cited by 29 · see citing works

Motion of proximal histidine and structural allosteric transition in soluble guanylate cyclase

Yoo, B., Lamarre, I., Martin, J. L., Rappaport, F., & Négrerie, M. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1423098112 · Cited by 25 · see citing works

Breaking the Proximal FeII–NHis Bond in Heme Proteins through Local Structural Tension: Lessons from the Heme b Proteins Nitrophorin 4, Nitrophorin 7, and Related Site-Directed Mutant Proteins

He, C., Neya, S., & Knipp, M. (2011) · Biochemistry · doi:10.1021/bi201073t · Cited by 24 · see citing works

A Heme-based Redox Sensor in the Methanogenic Archaeon Methanosarcina acetivorans

Molitor, B., Stassen, M., Modi, A. R., El‐Mashtoly, S. F., Laurich, C., Lubitz, W., Dawson, J. H., Rother, M., & Frankenberg‐Dinkel, N. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.476267 · Cited by 24 · see citing works

Picosecond to Second Dynamics Reveals a Structural Transition inClostridium botulinumNO-Sensor Triggered by the Activator BAY-41-2272

Yoo, B., Lamarre, I., Rappaport, F., Nioche, P., Raman, C. S., Martin, J. L., & Négrerie, M. (2012) · ACS Chemical Biology · doi:10.1021/cb3003539 · Cited by 24 · see citing works

Binding of YC-1 or BAY 41-2272 to Soluble Guanylyl Cyclase Induces a Geminate Phase in CO Photolysis

Hu, X., Feng, C., Hazzard, J. T., Tollin, G., & Montfort, W. R. (2008) · Journal of the American Chemical Society · doi:10.1021/ja804103y · Cited by 21 · see citing works

Cytochromes: Reactivity of the “dark side” of the heme

Ascenzi, P., Santucci, R., Coletta, M., & Polticelli, F. (2010) · Biophysical Chemistry · doi:10.1016/j.bpc.2010.09.008 · Cited by 20 · see citing works

Nonequilibrium Dynamics Simulations of Nitric Oxide Release: Comparative Study of Nitrophorin and Myoglobin

Kondrashov, D. A., & Montfort, W. R. (2007) · The Journal of Physical Chemistry B · doi:10.1021/jp071136n · Cited by 19 · see citing works

Dysregulation of TRPV4, eNOS and caveolin-1 contribute to endothelial dysfunction in the streptozotocin rat model of diabetes

Shamsaldeen, Y. A., Lione, L. A., & Benham, C. D. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173441 · Cited by 19 · see citing works

Regulatory effects of curcumin on nitric oxide signaling in the cardiovascular system

Abolfazli, S., Mortazavi, P., Kheirandish, A., Butler, A. E., Jamialahmadi, T., & Sahebkar, A. (2023) · Nitric Oxide · doi:10.1016/j.niox.2023.12.003 · Cited by 18 · see citing works

H-NOX domains display different tunnel systems for ligand migration

Zhang, Y., Lu, M. W., Cheng, Y., & Li, Z. (2010) · Journal of Molecular Graphics and Modelling · doi:10.1016/j.jmgm.2010.02.007 · Cited by 18 · see citing works

Activation of aminoimidazole carcinogens by nitrosation: Mutagenicity and nucleotide adducts

Zenser, T. V., Lakshmi, V. M., Schut, H. A. J., Zhou, H., & Josephy, P. D. (2009) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2008.12.007 · Cited by 17 · see citing works

Nitric Oxide Production and Regulation in the Teleost Cardiovascular System

Giordano, D., Verde, C., & Corti, P. (2022) · Antioxidants · doi:10.3390/antiox11050957 · Cited by 17 · see citing works

Conformationally Distinct Five-Coordinate Heme–NO Complexes of Soluble Guanylate Cyclase Elucidated by Multifrequency Electron Paramagnetic Resonance (EPR)

Gunn, A., Derbyshire, E. R., Marletta, M. A., & Britt, R. D. (2012) · Biochemistry · doi:10.1021/bi300831m · Cited by 15 · see citing works

A novel insight into the heme and NO/CO binding mechanism of the alpha subunit of human soluble guanylate cyclase

Zhong, F., Pan, J., Liu, X., Wang, H., Ying, T., Su, J., Huang, Z., & Tan, X. (2011) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s00775-011-0811-x · Cited by 14 · see citing works

Impaired iNOS–sGC–cGMP signalling contributes to chronic hypoxic and hypercapnic pulmonary hypertension in rat

Xia, X., Xu, Z., Hu, X., Wu, C., Dai, Y., & Yang, L. (2012) · Cell Biochemistry and Function · doi:10.1002/cbf.2796 · Cited by 13 · see citing works

Immunohistochemical and functional characterization of nitric oxide signaling pathway in isolated aorta from Crotalus durissus terrificus

Mónica, F. Z., Rojas-Moscoso, J. A., Porto, M., Schenka, A. A., Antunes, E., Cogo, J. C., & Nucci, G. D. (2011) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2011.11.003 · Cited by 13 · see citing works

ALCOHOL DOES NOT MODULATE THE AUGMENTED ACETYLCHOLINE-INDUCED VASODILATORY RESPONSE IN HEMORRHAGED RODENTS

Molina, M. F., Whitaker, A. M., Molina, P. E., & McDonough, K. H. (2009) · Shock · doi:10.1097/shk.0b013e31819e2b9a · Cited by 13 · see citing works

Inhibition of NOS1 promotes the interferon response of melanoma cells

Chen, X., Zou, Z., Wang, Q., Gao, W., Zeng, S., Ye, S., Xu, P., Huang, M., Li, K., Chen, J., et al. (2022) · Journal of Translational Medicine · doi:10.1186/s12967-022-03403-w · Cited by 12 · see citing works

NO Binding to the Proapoptotic Cytochrome c–Cardiolipin Complex

Hough, M. A., Silkstone, G. G. A., Worrall, J. A. R., & Wilson, M. T. (2014) · Vitamins and hormones · doi:10.1016/b978-0-12-800254-4.00008-8 · Cited by 12 · see citing works

Ligand-Based Regulation of Dynamics and Reactivity of Hemoproteins

Turilli-Ghisolfi, E. S., Lualdi, M., & Fasano, M. (2023) · Biomolecules · doi:10.3390/biom13040683 · Cited by 11 · see citing works

Production of Dioxygen in the Dark: Dismutases of Oxyanions

DuBois, J. L., & Ojha, S. (2014) · Metal ions in life sciences · doi:10.1007/978-3-319-12415-5_3 · Cited by 11 · see citing works

Recent History of Heme-Containing Proteins: Advances in Structure, Functions, and Reaction Intermediate Determination

Collins, D. P., & Dawson, J. H. (2013) · Elsevier eBooks · doi:10.1016/b978-0-08-097774-4.00306-5 · Cited by 10 · see citing works

Azanone (HNO) interaction with Hemeproteins and metalloporphyrins

Doctorovich, F. A., Bikiel, D. E., Pellegrino, J., Suárez, S., & Marti, M. A. (2012) · Advances in inorganic chemistry · doi:10.1016/b978-0-12-396462-5.00004-0 · Cited by 10 · see citing works

Isocyanide or nitrosyl complexation to hemes with varying tethered axial base ligand donors: synthesis and characterization

Sharma, S. K., Kim, H., Rogler, P. J., Siegler, M. A., & Karlin, K. D. (2016) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s00775-016-1369-4 · Cited by 9 · see citing works

Vasodilatory effect of formaldehyde via the NO/cGMP pathway and the regulation of expression of KATP, BKCa and L-type Ca2+ channels

Zhao, Y. S., Ge, J., Li, X., Guo, Q., Zhu, Y., Song, J., Zhang, L., Ding, S., Yang, X., & Li, R. (2019) · Toxicology Letters · doi:10.1016/j.toxlet.2019.04.006 · Cited by 9 · see citing works

Cryo-EM density map fitting driven in-silico structure of human soluble guanylate cyclase (hsGC) reveals functional aspects of inter-domain cross talk upon NO binding

Khalid, R. R., Maryam, A., Fadouloglou, V. E., Siddiqi, A. R., & Zhang, Y. (2019) · Journal of Molecular Graphics and Modelling · doi:10.1016/j.jmgm.2019.04.009 · Cited by 8 · see citing works

Density functional theory studies on a designed photoactive {FeNO}6 nitrosyl and the corresponding photoinactive {FeNO}7 species: Insight into the origin of NO photolability

Fry, N. L., Zhao, X. P., & Mascharak, P. K. (2010) · Inorganica Chimica Acta · doi:10.1016/j.ica.2010.12.041 · Cited by 8 · see citing works

Heme delivery into soluble guanylyl cyclase requires a heme redox change and is regulated by NO and Hsp90 by distinct mechanisms

Dai, Y., & Stuehr, D. J. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2025.108315 · Cited by 7 · see citing works

Decoding the enigmatic last gasotransmitter. The intriguing journey of HNO: From hidden origins to clues on reactivity and detection

Suárez, S. (2024) · Redox Biochemistry and Chemistry · doi:10.1016/j.rbc.2024.100024 · Cited by 7 · see citing works

Native Alanine Substitution in the Glycine Hinge Modulates Conformational Flexibility of Heme Nitric Oxide/Oxygen (H-NOX) Sensing Proteins

Hespen, C. W., Bruegger, J. J., Guo, Y., & Marletta, M. A. (2018) · ACS Chemical Biology · doi:10.1021/acschembio.8b00248 · Cited by 7 · see citing works

Prenatal hypothyroidism diminished exogenous NO-mediated diastolic effects in fetal rat thoracic aorta smooth muscle via increased oxidative stress

Guo, J. X., Yu, X., Liu, Y., Lu, L., Zhu, D., Zhang, Y., Li, L., Zhang, P., Gao, Q., Lu, X., et al. (2022) · Reproductive Toxicology · doi:10.1016/j.reprotox.2022.08.009 · Cited by 7 · see citing works

Cell-specific expression and immunolocalization of nitric oxide synthase isoforms and soluble guanylyl cyclase α and β subunits in postnatal porcine uteri

Li, Y., Zhou, X., Wei, Q., Huang, R., & Shi, F. (2013) · Acta Histochemica · doi:10.1016/j.acthis.2013.10.003 · Cited by 6 · see citing works

Oxygen Mediates Vascular Smooth Muscle Relaxation in Hypoxia

Dada, J., Pinder, A. G., Lang, D., & James, P. E. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057162 · Cited by 6 · see citing works

Theoretical investigation on the diatomic ligand migration process and ligand binding properties in non‐O2‐binding H‐NOX domain

Zhang, Y., Liu, L., Wu, L., Li, S., Li, F., & Li, Z. (2013) · Proteins Structure Function and Bioinformatics · doi:10.1002/prot.24279 · Cited by 6 · see citing works

NMR Studies of the Dynamics of Nitrophorin 2 Bound to Nitric Oxide

Dhanasekaran, M., Berry, R. E., Zhang, H., & Walker, F. A. (2013) · Biochemistry · doi:10.1021/bi4010396 · Cited by 6 · see citing works

1H, 13C, 15N backbone and side-chain resonance assignment of Nostoc sp. C139A variant of the heme–nitric oxide/oxygen binding (H-NOX) domain

Alexandropoulos, I. I., Argyriou, A. I., Marousis, K. D., Topouzis, S., Papapetropoulos, A., & Spyroulias, G. A. (2016) · Biomolecular NMR Assignments · doi:10.1007/s12104-016-9707-6 · Cited by 6 · see citing works

Structural and functional insights into the heme-binding domain of the human soluble guanylate cyclase α2 subunit and heterodimeric α2β1

Wang, H., Zhong, F., Pan, J., Li, W., Su, J., Huang, Z., & Tan, X. (2012) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s00775-012-0891-2 · Cited by 5 · see citing works

Purification and characterization of recombinant human soluble guanylate cyclase produced from baculovirus-infected insect cells

Emmons, T. L., Mathis, K. J., Shuck, M. E., Reitz, B. A., Curran, D. F., Walker, M. C., Leone, J. W., Day, J. E., Bienkowski, M. J., Fischer, H., et al. (2009) · Protein Expression and Purification · doi:10.1016/j.pep.2009.01.001 · Cited by 5 · see citing works

Maprotiline Prevents Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats

Tong, Y., Jiao, Q., Liu, Y., Lv, J., Wang, R., & Zhu, L. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01032 · Cited by 5 · see citing works

Maintenance of Cardiac Microenvironmental Homeostasis: A Joint Battle of Multiple Cells

Yao, J., Zhang, Y., Wang, Z., Chen, Y., & Shi, X. (2024) · Journal of Cellular Physiology · doi:10.1002/jcp.31496 · Cited by 4 · see citing works

THRA1/PGC-1α/SIRT3 pathway regulates oxidative stress and is implicated in hypertension of maternal hypothyroid rat offspring

Guo, J., Shi, Y.-J., Yu, X., Zhao, Y., Wei, B., Huo, M., Lu, L.-K., Li, L., Gao, Q.-Q., & Sun, M. (2024) · Hypertension Research · doi:10.1038/s41440-024-02023-9 · Cited by 4 · see citing works

Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble Guanylate Cyclase to Inhibit Abnormal Vasomotion

Yang, S., Zhao, Y., Cheng, X., Zhan, T., Tian, J., Liu, X., Ma, C., Wang, Z., Jin, L.-Y., Liu, Q., et al. (2023) · Engineering · doi:10.1016/j.eng.2023.06.009 · Cited by 3 · see citing works

Morphological and functional analysis of saccus vasculosus of mandarin fish ( Siniperca chuatsi )

Aly, R. S. S., Fang, J., Li, K., Ma, X., Gao, J., Zhang, M., Chen, X., & Shen, Y. (2025) · Journal of Fish Biology · doi:10.1111/jfb.70232 · Cited by 3 · see citing works

Modulation of Cellular Respiration by Endogenously Produced Nitric Oxide in Rat Hippocampal Slices

Ledo, A., Barbosa, R. M., & Laranjinha, J. A. N. (2011) · Methods in molecular biology · doi:10.1007/978-1-61779-382-0_5 · Cited by 3 · see citing works

Beyond eNOS: Genetic influence in NO pathway affecting drug response

Esposito, A., Filho, C. K. C., & Lacchini, R. (2022) · Genetics and Molecular Biology · doi:10.1590/1678-4685-gmb-2022-0157 · Cited by 3 · see citing works

Molecular steps in soluble guanylate cyclase activation

Boon, E. M., Cary, S. P., Huang, S. H., Winger, J. A., & Marletta, M. A. (2005) · BMC Pharmacology · doi:10.1186/1471-2210-5-s1-s1

A molecular basis for nitric oxide sensing by soluble guanylate cyclase

Zhao, Y., Brandish, P. E., Ballou, D. P., & Marletta, M. A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.26.14753 · Cited by 323 · see citing works

Structure and Activation of Soluble Guanylyl Cyclase, the Nitric Oxide Sensor

Montfort, W. R., Wales, J. A., & Weichsel, A. (2017) · Antioxidants & Redox Signaling · doi:10.1089/ars.2016.6693 · Cited by 144 · see citing works

On the activation of soluble guanylyl cyclase by nitric oxide

Bellamy, T. C., Wood, J., & Garthwaite, J. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.012368499 · Cited by 141 · see citing works

Structure and Regulation of Soluble Guanylate Cyclase

Derbyshire, E. R., & Marletta, M. A. (2012) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-050410-100030 · Cited by 466 · see citing works