The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.
Mismatch negativity potentials and cognitive impairment in schizophrenia
Abstract
Cognitive impairment in schizophrenia is an important predictor of clinical and social outcome. In this preliminary study, the correlation between cognitive status and deficits in mismatch negativity (MMN) generation was explored. The MMN response to tone duration deviants was recorded using a new stimulation protocol with continuously changing ('roving') standard stimuli in order to measure the effect of standard repetitions on MMN (memory trace effect). Cognitive status of the patient group (n=28) was assessed using neuropsychological screening. Healthy participants (n=20) served as age-matched comparison group. In patients, MMN amplitude in frontal electrodes as well as the MMN memory trace effect was diminished compared to controls. While both measures were inversely related to patient's age and disease severity, only the MMN memory trace effect was robustly correlated with the degree of neuropsychological impairment. This suggests that ERP measures of auditory system adaptability more appropriately characterise the pathophysiological processes underlying cognitive impairment in schizophrenia than static measures of ERP magnitude.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“They found that healthy controls showed larger MMN amplitudes under longer repetition conditions, while repetition showed no effect on MMN for patients with schizophrenia.”
From A Predictive Coding Perspective on Mismatch Negativity Impairment in Schizophrenia (2020) · cites this paper as [28]
In the citing paper
“They found that healthy controls showed larger MMN amplitudes under longer repetition conditions, while repetition showed no effect on MMN for patients with schizophrenia.”
From A Predictive Coding Perspective on Mismatch Negativity Impairment in Schizophrenia (2020) · cites this paper as [28]
Citations
Cites
Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282
Rao, R. P. N., & Ballard, D. H. (1999) · Nature Neuroscience · doi:10.1038/4580 · Cited by 5,483
The molecular biology of memory storage: a dialogue between genes and synapses
Kandel, E. R. (2001) · Science · doi:10.1126/science.1067020 · Cited by 3,917
What are the functional consequences of neurocognitive deficits in schizophrenia?
(1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.3.321 · Cited by 3,516
Krystal, J. H. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950030035004 · Cited by 3,330
Recent advances in the phencyclidine model of schizophrenia
(1991) · American Journal of Psychiatry · doi:10.1176/ajp.148.10.1301 · Cited by 2,904
Risto, N. (2018) · Routledge eBooks · doi:10.4324/9780429487354 · Cited by 2,035
McCarthy, G., & Wood, C. C. (1985) · Electroencephalography and Clinical Neurophysiology/Evoked Potentials Section · doi:10.1016/0168-5597(85)90015-2 · Cited by 1,765
The neuropathology of schizophrenia
Harrison, P. J. (1999) · Brain · doi:10.1093/brain/122.4.593 · Cited by 1,677
Wijers, B. (1995) · Acta Psychologica · doi:10.1016/0001-6918(95)90043-8 · Cited by 1,319
Research works printed but not linked: 2
- Krljes, 2002, Mismatch negativity deficit is related to general memory impairment in schizophrenia, Schizophrenia Research, 53, 17
- Wechsler, 1945, A standardised memory scale for clinical use, Psychology, 19, 87
Cited by
Sorted by citations
Items 201–300 of 321
Neural correlates of auditory sensory memory dynamics in the aging brain
Sur, S., & Golob, E. J. (2019) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2019.12.020 · Cited by 10
O’Reilly, J. A. (2021) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2021.09.003 · Cited by 9
Weber, L. A. E., Diaconescu, A. O., Mathys, C. D., Schmidt, A., Kometer, M., Vollenweider, F. X., & Stephan, K. E. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/528372 · Cited by 10
“Electroencephalographic (EEG) activity was recorded during an auditory “roving” oddball paradigm, originally developed by (43) and subsequently modified by (44).”
BackgroundMethodThe effect of deviance predictability on mismatch negativity in schizophrenia patients
Horacek, M., Kärgel, C., Scherbaum, N., & Müller, B. W. (2016) · Neuroscience Letters · doi:10.1016/j.neulet.2016.02.010 · Cited by 9
“Reviews have established these findings to a degree that includes the consideration of MMN amplitude reductions as a biomarker and endophenotype of schizophrenia with relations to symptoms, cognition and global functioning [3, 4, 11, 15, 32].”
BackgroundMismatch negativity predicts age-related declines in memory precision
Chow, R., Baker, S., Mo, S., Bugos, J. A., Alain, C., & Rosenbaum, R. S. (2024) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2024.11.012 · Cited by 10
Inaba, H., Kai, R., Namba, H., Sotoyama, H., Jodo, E., Nin, F., Hibino, H., Yabe, H., Eifuku, S., Horii, A., et al. (2020) · Schizophrenia Bulletin Open · doi:10.1093/schizbullopen/sgaa070 · Cited by 9
“48 Compared with our pilot study on frequency MMN of the same EGF-challenged rats, the electrode position detecting MMN-like potential was different; frequency MMN-like potentials were recorded from the electrode on the frontal cortex, whereas the present dMMN-like potentials were from that of the…”
Junghöfer, M., Bröckelmann, A., Kueppers, K. A., Ohrmann, P., & Pedersen, A. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.11.025 · Cited by 9
“Interestingly, prefrontal dysfunction in schizophrenia correlate with negative symptoms, such as social withdrawal (Baldeweg et al., 2004), and have, thus, been interpreted as dampened frontal attention switching towards salient auditory cues.”
BackgroundChoueiry, J., Blais, C. M., Shah, D. K., Smith, D., Fisher, D. J., Ilivitsky, V., & Knott, V. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05646-1 · Cited by 9
Coy, N., Bendixen, A., Grimm, S., Roeber, U., & Schröger, E. (2024) · Psychophysiology · doi:10.1111/psyp.14545 · Cited by 8
Do Auditory Mismatch Responses Differ Between Acoustic Features?
An, H., Kei, S. H., Auksztulewicz, R., & Schnupp, J. W. H. (2021) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2021.613903 · Cited by 8
“In an additional control analysis, we have tested whether the mismatch responses observed in this study were modulated by adaptation effects, which have been shown to be especially prominent in the N1 range (Baldeweg et al., 2004).”
MethodElls, E. M. L., Rudolph, E. D., Petley, L., Abriel, S. C., Campbell, D. J., Tibbo, P. G., & Fisher, D. J. (2018) · Biological Psychology · doi:10.1016/j.biopsycho.2018.03.010 · Cited by 8
The Imbalanced Plasticity Hypothesis of Schizophrenia-Related Psychosis: A Predictive Perspective
Guterman, Y., Ataria, Y., & Silverstein, S. M. (2021) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-021-00911-y · Cited by 10
The Neurobiology of Schizophrenia
Bobo, W. V., Rapoport, J. L., Abi‐Dargham, A., Fatemi, S. H., & Meltzer, H. Y. (2015) · Wiley eBooks · doi:10.1002/9781118753378.ch19 · Cited by 8
Knott, V., Wright, N. P., Shah, D. K., Baddeley, A., Bowers, H., de la Salle, S., & Labelle, A. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00555 · Cited by 9
“80) (55, 56); it is an automatic sensory process that is relatively free of attentional and motivational confounds that influence effortdemanding, higher order cognitive operations (57); and finally, because MMN has strong external face validity (in that it is positively related to performance in behavioral tasks of s…”
BackgroundKu, B. S., Hamilton, H., Yuan, Q. E., Parker, D., Roach, B. J., Bachman, P., Belger, A., Carrión, R. E., Duncan, E., Johannesen, J., et al. (2025) · Neuropsychopharmacology · doi:10.1038/s41386-025-02093-4 · Cited by 7
The mismatch negativity (MMN): An introduction
Näätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.003.0001 · Cited by 8
Oxner, M., Rosentreter, E. T., Hayward, W. G., & Corballis, P. M. (2019) · Journal of Vision · doi:10.1167/19.6.9 · Cited by 7
Attention modulates repetition effects in a context of low periodicity
Hsu, Y., Darriba, Á., & Waszak, F. (2021) · Brain Research · doi:10.1016/j.brainres.2021.147559 · Cited by 7
“…ms at frontocentral electrodes in the ERPs to standard sounds that increases its amplitude with increasing number of repetitions in the roving paradigm (Baldeweg et al., 1999, 2004), no matter whether participants are actively or passively listening to the auditory stimuli (Haenschel et al., 2005).”
Neural repetition suppression to vocal and non-vocal sounds
Heurteloup, C., Merchie, A., Roux, S., Bonnet‐Brilhault, F., Escera, C., & Gomot, M. (2021) · Cortex · doi:10.1016/j.cortex.2021.11.020 · Cited by 7
Mismatch Negativity in Patients with Schizophrenia
Urban, A., Kremláček, J., & Libiger, J. (2007) · Acta Medica (Hradec Kralove Czech Republic) · doi:10.14712/18059694.2017.55 · Cited by 7
“He found a negative correlation between MMN and the degree of neuropsychological impairment (4).”
BackgroundLarsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Olsen, L., Didriksen, M., Baaré, W. F. C., Werge, T. M., Garrido, M. I., & Siebner, H. R. (2019) · NeuroImage Clinical · doi:10.1016/j.nicl.2019.101721 · Cited by 7
The Somatosensory Mismatch Negativity
Grundei, M., von der Behrens, W., Astikainen, P., Wetzel, N., & Blankenburg, F. (2025) · European Journal of Neuroscience · doi:10.1111/ejn.70301 · Cited by 7
“…modality have switched the roles of standard and deviant features within a stimulus sequence (“roving-oddball paradigm,” e.g., Cowan et al. 1993; Baldeweg et al. 2004) or in different experimental blocks (“block-flip paradigm,” e.g., Harms et al. 2014; Fishman 2014) and averaged responses to…”
Seol, J. J., Kim, M., Lee, K. H., Hur, J., Cho, K. I. K., Lee, T. Y., Chung, C. K., & Kwon, J. S. (2017) · Clinical EEG and Neuroscience · doi:10.1177/1550059417714705 · Cited by 6
“to the robust MMN attenuations we observe in schizophrenia patients.(35) Overall, in accordance with evidence of right hemi-”
ResultAuditory Pattern Representations Under Conditions of Uncertainty—An ERP Study
Bader, M., Schröger, E., & Grimm, S. (2021) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2021.682820 · Cited by 6
“Likely, both standard and deviant ERPs contribute to the MMN increase with deviant ERPs growing more negative and standard ERPs growing more positive (and vice versa for the P3a) as a function of the number of previous standards in a train (Baldeweg et al., 2004; Bendixen et al., 2007; Costa-Faidella et al., 2011; Bad…”
BackgroundSynchronized tapping facilitates learning sound sequences as indexed by the P300
Kamiyama, K. S., & Okanoya, K. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00826 · Cited by 6
“It was reported that the MMN amplitude was affected by the presentation frequency of standard stimuli (Baldeweg et al., 2004; Haenschel et al., 2005), short-term discrimination trainings (Kraus et al.”
BackgroundO’Reilly, J. A., Zhu, J. D., & Sowman, P. F. (2023) · Journal of Neural Engineering · doi:10.1088/1741-2552/acef94 · Cited by 6
Mazer, P., Macedo, I., Paiva, T. O., Ferreira‐Santos, F., Pasion, R., Barbosa, F., Almeida, P. R., Silveira, C., Cunha-Reis, C., & Teixeira, J. M. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.630406 · Cited by 6
“Using a modified version of the roving standard frequency paradigm (35), auditory stimuli (i.”
Auditory Event-Related Potentials
Winkler, I., Denham, S. L., & Escera, C. (2022) · Springer eBooks · doi:10.1007/978-1-0716-1006-0_99 · Cited by 7
Neural Correlates of Automatic and Controlled Auditory Processing in Schizophrenia
Morey, R. A., Mitchell, T. V., Inan, S., Lieberman, J. A., & Belger, A. (2008) · Journal of Neuropsychiatry · doi:10.1176/appi.neuropsych.20.4.419 · Cited by 5
Mismatch negativity and polygenic risk scores for schizophrenia and bipolar disorder
Pentz, A. B., O’Connel, K. S., van Jole, O., Timpe, C. M. F., Slapø, N. B., Melle, I. S., Lagerberg, T. V., Steen, N. E., Westlye, L. T., Haukvik, U. K., et al. (2024) · Schizophrenia Research · doi:10.1016/j.schres.2024.01.013 · Cited by 6
“Previous studies of the memory trace effects for MMN, RP, and DN in SCZ have reported inconsistent results (Baldeweg and Hirsch, 2015; Baldeweg et al., 2004; Javitt et al., 1998; Baldeweg et al., 2006; Coffman et al., 2017; McCleery et al., 2019).”
InfluentialOn the matching of top-down knowledge with sensory input in the perception of ambiguous speech
Eulitz, C., & Hannemann, R. (2010) · BMC Neuroscience · doi:10.1186/1471-2202-11-67 · Cited by 5
“Inside each train of this so called roving standard oddball paradigm [27,28] all items belonged to one stimulus class.”
MethodNeural surprise in somatosensory Bayesian learningPreprint
Gijsen, S., Grundei, M., Lange, R. T., Ostwald, D., & Blankenburg, F. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.06.18.158915 · Cited by 5
Towards a neurobiologically plausible model of language-related, negative event-related potentialsPreprint
Bornkessel‐Schlesewsky, I., & Schlesewsky, M. (2018) · doi:10.31219/osf.io/aynsp · Cited by 6
Hamilton, H., Roach, B. J., Bachman, P., Belger, A., Carrión, R. E., Duncan, E., Johannesen, J., Light, G. A., Niznikiewicz, M. A., Addington, J., et al. (2024) · Clinical EEG and Neuroscience · doi:10.1177/15500594241294035 · Cited by 4
“Amplitude reduction of the mismatch negativity (MMN) event-related potential (ERP) component derived from electro-encephalography (EEG) recording is a well-established bio-marker of schizophrenia (see 1,2 ) that is sensitive to cognitive dysfunction 3 – 6 and poor functional outcomes.”
Hyperlearning Hypothesis: Network disruption and maladaptive learning in schizophrenia
Yuichi, T., Sunaga, M., Fujihara, K., Ohki, T., Kato, Y., & Jinde, S. (2025) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2025.111599 · Cited by 4
Model-Based Approaches to Investigating Mismatch Responses in Schizophrenia
Gütlin, D., McDermott, H. H., Grundei, M., & Auksztulewicz, R. (2024) · Clinical EEG and Neuroscience · doi:10.1177/15500594241253910 · Cited by 5
“…probability, 132 – 134 given the sensitivity of MMN to (un)expected stimulus repetitions, 2,135,136 which may be disrupted in schizophrenia 137,138 ; and (c) transition probability, 10,116,121,127,139 typical for Markovian stimulus sequences 140 and considered essential for probabilistic…”
Dheerendra, P., Grent-‘t-Jong, T., Gajwani, R., Groß, J., Gumley, A. I., Krishnadas, R., Lawrie, S. M., Schwannauer, M., Schultze‐Lutter, F., & Uhlhaas, P. J. (2023) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2023.09.006 · Cited by 4
(2024) · doi:10.1016/j.jneumeth.2024.110277 · Cited by 4
“The Deviant [p ɑː ] or [ b ̬ a : ] cluster were presented in randomized order and interleaved with the Standard [b ɑː ] cluster, similar to the “ roving ” Standard paradigm employed by Baldeweg et al. (2004).”
MethodSound frequency dependence of duration mismatch negativity recorded from awake rats
Inaba, H., Namba, H., Sotoyama, H., Narihara, I., Jodo, E., Yabe, H., Eifuku, S., & Nawa, H. (2019) · Neuropsychopharmacology Reports · doi:10.1002/npr2.12090 · Cited by 4
Action effect predictions in ‘what’, ‘when’, and ‘whether’ intentional actions
Chung, W. Y., Darriba, Á., Korka, B., Widmann, A., Schröger, E., & Waszak, F. (2022) · Brain Research · doi:10.1016/j.brainres.2022.147992 · Cited by 4
“…and mispredicted action-effects parallels explanations proposed to explain the MMN manifesting and getting larger along the number of repetitions of standard stimuli in repetition suppression studies (Baldeweg et al., 2004; Haenschel, 2005), in which predictions are based on sensory evidence.”
Huang, W., Wang, Y., Qin, J., He, C., Li, Y., Wang, Y., Li, M., Lyu, J., Zhou, Z., Jia, H., et al. (2022) · Neuroreport · doi:10.1097/wnr.0000000000001851 · Cited by 3
Mismatch negativity as an early biomarker of cognitive impairment in schizophrenia
Mahmoud, A. M. A., Eissa, M. A.-R., Kolkaila, E. A., Amer, R. A. R., & Kotait, M. A. (2023) · The Egyptian Journal of Neurology Psychiatry and Neurosurgery · doi:10.1186/s41983-023-00627-5 · Cited by 6
“Baldeweg and colleague [43] also delineated a significant association regarding the drop of MMN amplitude measures with duration deviant stimuli and several cognitive domains including verbal fluency, executive function and episodic memory.”
BackgroundAeberli, T., Müller, M., Theodoridou, A., Hagenmuller, F., Seifritz, E., Walitza, S., Wulf Rössler, A., Kawohl, W., & Heekeren, K. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1130809 · Cited by 4
Trait and State Anxiety Effects on Mismatch Negativity and Sensory Gating Event-Related Potentials
Ioakeimidis, V., Lennuyeux-Comnene, L., Khachatoorian, N., Gaigg, S., Haenschel, C., Kyriakopoulos, M., & Dima, D. (2023) · Brain Sciences · doi:10.3390/brainsci13101421 · Cited by 4
“Hence, MMN is mediated by a complex interplay of top-down and bottom-up connection dynamics [4], with frontal feedback signals mediating attentional reorienting and temporal feedforward connections regulating sensory memory encoding [3,35].”
BackgroundSärkämö, T. (2011) · Cited by 4
Neurovascular coupling: insights from multi-modal dynamic causal modelling of fMRI and MEGPreprint
Jafarian, A., Vladimir Litvak, A., Cagnan, H., Friston, K. J., & Zeidman, P. (2019) · arXiv (Cornell University) · doi:10.48550/arxiv.1903.07478 · Cited by 4
“conducted in accordance with the Ethics Committee of University College London, UCL Ethics Ref: 1825/003 (MRI) and Ref: 1825/005 (MEG). The task was a variant of the auditory roving oddball paradigm (Baldeweg et al. 2004), which has been extensively characterised in patient and control populations using DCM (e.g. Boly…”
MethodModel-based prediction of muscarinic receptor function from auditory mismatch negativity responsesPreprint
Schöbi, D., Jung, F., Frässle, S., Endepols, H., Moran, R., Friston, K. J., Tittgemeyer, M., Heinzle, J., & Stephan, K. E. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.06.08.139550 · Cited by 5
“As an experimental paradigm, we chose the auditory mismatch negativity (MMN) which is reliably impaired in schizophrenia (Baldeweg et al., 2004; Umbricht and Krljes, 2005; Erickson et al., 2016) and is sensitive to cholinergic manipulations (for review, see (Garrido et al., 2009)).”
MethodWynn, J. K., & Green, M. F. (2024) · Clinical EEG and Neuroscience · doi:10.1177/15500594241252897 · Cited by 3
“The roving MMN has only rarely been used in SCZ, 26,31,32 with results being consistent with prediction error coding de fi cits, but has never been assessed in TBI.”
MethodResultInfluentialInaba, H., Namba, H., Kida, S., & Nawa, H. (2021) · Neuropsychopharmacology Reports · doi:10.1002/npr2.12199 · Cited by 2
Deviance Detection Property in Dissociated Cultures of Neurons
Kubota, T., Sakurayama, K., Shiramatsu, T. I., & Takahashi, H. (2021) · IEEJ Transactions on Electronics Information and Systems · doi:10.1541/ieejeiss.141.661 · Cited by 3
Fujitani, S., Kunii, N., Nagata, K., Takasago, M., Shimada, S., Tada, M., Kirihara, K., Komatsu, M., Uka, T., Kasai, K., et al. (2024) · Cerebral Cortex · doi:10.1093/cercor/bhad508 · Cited by 3
Näätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.003.0003 · Cited by 5
Bruzzone, S. E. P., Haumann, N. T., Kliuchko, M., Vuust, P., & Brattico, E. (2021) · Clinical Neurophysiology · doi:10.1016/j.clinph.2021.05.007 · Cited by 3
Teichert, T., Jedema, H. P., Shen, Z., & Gurnsey, K. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2019.12.18.881821 · Cited by 3
“To approach this issue empirically, we modified the commonly used roving-standard paradigm (Baldeweg et al., 2004; Christianson et al., 2014; Costa-Faidella et al., 2011; Garrido et al., 2008; Lieder et al., 2013; Schröger and Wolff, 1996; Teichert et al., 2016) in a way that allowed us to measure…”
MethodAre There Non‐Mammalian Models of Mismatch Negativity? A Translational Tribute to Risto Näätänen
Chahlova, S. S., Stewart, A., Galstyan, D. S., de Abreu, M. S., & Kalueff, A. V. (2025) · European Journal of Neuroscience · doi:10.1111/ejn.70200 · Cited by 2
“…replicable finding with large effect sizes, evidence is mixed as for whether this solely reflects an impaired response to deviation, or represents an impaired response to deviation and impaired encoding of regularity (Rentzsch et al. 2015; Javitt 2023; Baldeweg et al. 2004; Erickson et al. 2016).”
Multi-feature mismatch negativity: How can reliable data be recorded in a short time?
Atalık, G., Yağcıoğlu, S., Yiğit, Ö., Belgi̇n, E., Sendesen, E., & Türkyılmaz, M. D. (2022) · Clinical Neurophysiology · doi:10.1016/j.clinph.2022.09.007 · Cited by 2
Fante, E. D., Piovesan, F., Sarasso, P., Barbieri, P., Villa, M.-C., Sacco, K., & Ronga, I. (2024) · Cyberpsychology Behavior and Social Networking · doi:10.1089/cyber.2023.0336 · Cited by 2
“22,23 In the roving paradigm, the same stimulus could be either deviant or standard depending on its position, with equal probability.”
Erickson, M. A., Bansal, S., Li, C., Waltz, J. A., Corlett, P. R., & Gold, J. M. (2024) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2024.100394 · Cited by 2
An ace in the hole? Opportunities and limits of using mice to understand schizophrenia neurobiology
Villarin, J. M., & Kellendonk, C. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03060-7 · Cited by 2
“It correlates well with cognitive dysfunctions and overall disease severity in schizophrenia [35, 36], as well as with auditory hallucinations during acute psychotic states [37].”
Teichert, T., Jedema, H. P., Shen, Z., & Gurnsey, K. (2025) · Journal of Neurophysiology · doi:10.1152/jn.00515.2024 · Cited by 6
Can new paradigms bring new perspectives for mismatch negativity studies in schizophrenia?
Jarkiewicz, M., & Wichniak, A. (2015) · Neuropsychiatric Electrophysiology · doi:10.1186/s40810-015-0010-z · Cited by 2
“Research using a roving paradigm in which the standard stimuli were varied provided more insight into dysfunction of MMN mechanism in schizophrenia as it provided evidence for deficits in the formation of memory traces for standards (Baldeweg et al. 2004; Baldeweg and Hirsch 2014).”
BackgroundMethodResultInfluentialInterrelation of reduction of mismatch negativity and cognitive deficit in paranoid schizophrenia
1, P. D. №., Petrov, M. V., Kolchev, A. I., Ершов, Б. Б., Gvozdetskiy, A., Golovanova, I. V., Daeva, N., & 7, T. C. P. D. N. (2017) · Vestnik of Saint Petersburg University Psychology · doi:10.21638/11701/spbu16.2017.107 · Cited by 2
Pakarinen, S. (2011) · Työväentutkimus Vuosikirja · Cited by 2
Unraveling neural adaptation to vocal and non-vocal sounds in autism
Merchie, A., Bonnet‐Brilhault, F., Escera, C., Houy‐Durand, E., & Gomot, M. (2024) · Clinical Neurophysiology · doi:10.1016/j.clinph.2024.12.003 · Cited by 1
“This paradigm allows to measure neural adaptation thanks to a constant updating of the memory trace (Baldeweg et al., 2004, 1999; Cowan et al., 1993; Haenschel et al., 2005).”
Harenbrock, J., Schloßmacher, I., Todd, J., & Straube, T. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106534 · Cited by 5
Kirasirova, L., Archakov, D., Клочко, Н., Batsunov, A., Skobeleva, K., Sagalajev, B., & Tugin, S. (2026) · Journal of Visualized Experiments · doi:10.3791/69817 · Cited by 1
Functional and Structural Endophenotypes in Schizophrenia
Bender, S., Weisbrod, M., & Resch, F. (2009) · Springer eBooks · doi:10.1007/978-1-4020-9831-4_4 · Cited by 1
Neurophysiology of Cognitive Dysfunction in Schizophrenia
Haenschel, C., & Linden, D. E. J. (2011) · Springer eBooks · doi:10.1007/978-94-007-0831-0_18 · Cited by 1
Decoding of auditory surprise in adult magnetoencephalography data using Bayesian models
Tavoosi, P., Azemi, G., & Sowman, P. F. (2024) · Digital Signal Processing · doi:10.1016/j.dsp.2024.104450 · Cited by 1
Visual mismatch negativity is more than the sum of microsequences
Kővári, L., Kojouharova, P., Gaál, Z. A., & Czigler, I. (2024) · Biological Psychology · doi:10.1016/j.biopsycho.2024.108956 · Cited by 1
“The non-oddball condition is a variety of the roving standard paradigms of (auditory) MMN (e.g. Baldeweg et al., 2004; Cooper et al., 2008; Garrido et al., 2008a; Winkler et al., 1996a, 1996b) and vMMN (Oxner et al., 2019; Schlossmacher et al., 2020; Stefanics et al., 2020; Sulykos et al., 2013)…”
Saperstein, A. M., Brennan, R., Qian, M., Javitt, D. C., & Medalia, A. A. (2025) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaf017 · Cited by 1
Hsu, Y., Vincent, R., & Waszak, F. (2015) · Brain Research · doi:10.1016/j.brainres.2015.05.029 · Cited by 1
“Moreover, the degree of impairment in such basic auditory plasticity seems to correlate with markers of schizophrenia severity, such as cognitive and functional impairment (Baldeweg et al., 2004; Baldeweg, 2006).”
Mismatch Negativity as a Psychophysiological Index of Cognitive Function in Schizophrenia
Nakagome, K. (2007) · Institutional Repositories DataBase (IRDB) · Cited by 1
Cortical multi-attribute auditory discrimination deficits and their amelioration in dyslexia
Lovio, R. (2013) · Työväentutkimus Vuosikirja · Cited by 1
Switch to ziprazidone treatment is associated with changes in MMN amplitude
Salazar, J., Ordoño, F., Soriano, S., Rueda, M., Ojeda, E., Cozar, R., & Belloch, V. (2009) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.01.016 · Cited by 1
“Recent findings have showed a robust correlation between the MMN and cognitive impairment in schizophrenia, suggesting that MMN may serve as a putative neural marker of deficits in NMDA-dependent neural processes underlying such impairment (Baldeweg et al., 2004).”
BackgroundMethodInfluentialDaly, M. P. (2014) · CUNY Academic Works (City University of New York) · Cited by 1
Applying SCA for high-accuracy cortical auditory ERPs in childrenPreprint
Bruzzone, S. E. P., Haumann, N. T., Kliuchko, M., Vuust, P., & Brattico, E. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.09.25.313809 · Cited by 1
“…sensory deficits (Cone-wesson & Wunderlich, 2003; Eggermont & Ponton, 2002; Oken & Phillips, 2009) as well as cognitive impairments (Akshoomoff & Courchesne, 1994; Baldeweg et al., 2004; Čeponienė et al., 2009; Friedman, 2003; R Näätänen et al., 2012; Sunohara et al., 1999; Wiersema et al., 2005).”
BackgroundCausal modelling of evoked brain responses.
Garrido, M. I. (2008) · UCL Discovery (University College London) · Cited by 1
Regularity encoding in the auditory brain as revealed by human evoked potentials
Costa‐Faidella, J. (2011) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
Auditory and speech processing in specific language impairment (SLI) and dyslexia
Tuomainen, O. (2009) · UCL Discovery (University College London)
Association between Mismatch Negativity and Functional Status in Patients with Schizophrenia
Kim, M. A., Kim, S. N., Lee, M. H., Lee, S., & Kwon, J. S. (2013) · Korean Journal of Schizophrenia Research · doi:10.16946/kjsr.2013.16.2.98
What rhythmic perception and amusia can tell us about vocal social communication in schizophreniaPreprint
Mitchell, R. L. C., Gamez, K., Bolgar, J., Neustadter, E. S., Calkins, M. E., Moore, T. M., & Leitman, D. I. (2016) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/092098
Age effects on auditory sensory memory: a cognitive neuroscience perspective
Cooper, R. J. (2009) · NOVA (University of Newcastle Australia)
Matziorinis, A. M., Moberget, T., & Elvsåshagen, T. (2017) · NORA - Norwegian Open Research Archives · doi:10.13140/rg.2.2.33351.52644
Näätänen, R., Paavilainen, P., Rinne, T., & Alho, K. (2007)
Näätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.003.0002
Skaug, K. A. (2018) · NORA - Norwegian Open Research Archives
Näätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.003.0008
Näätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.003.0005
Näätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.003.0004
Näätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.003.0007
Näätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.003.0006
Wang, C., Flemming, K., Cortiana, G., Putkinen, V., Lammert, J. M., Rafat, Y., Tao, S., & Joanisse, M. F. (2022) · Biological Psychology · doi:10.1016/j.biopsycho.2022.108449
Experimental Medicine Approaches in Early-Phase CNS Drug Development
English, B. A., & Ereshefsky, L. (2023) · Advances in neurobiology · doi:10.1007/978-3-031-21054-9_17
Näätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.002.0007
Metadata
- Authors
- Baldeweg, T., Klugman, A., Gruzelier, J., & Hirsch, S. R.
- Affiliations
- Great Ormond Street Hospital (GB)
- Charing Cross Hospital (GB)
- Corresponding author
- Baldeweg, Torsten
- ORCID
- Baldeweg, Torsten
- Venue
- Schizophrenia Research
- Publisher
- Elsevier BV
- Published
- 2004-08
- Volume
- 69
- Issue
- 2-3
- Pages
- 203-217
- ISSN
- 0920-9964 (ISSN-L)
- OpenAlex
- W2142009972
- Cited by
- 321
- References
- 64
- Citations by year
- 2026: 11 · 2025: 9 · 2024: 19 · 2023: 12 · 2022: 17 · 2021: 20 · 2020: 27 · 2019: 27 · 2018: 10 · 2017: 16 · 2016: 10 · 2015: 16 · 2014: 16 · 2013: 16 · 2012: 14
- FWCI
- 2.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Schizophrenia Research (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- mismatch negativity, schizophrenia
- MeSH terms
- Acoustic Stimulation, Adult, Brain Mapping, Cognition, Cognition Disorders, Contingent Negative Variation, Electroencephalography, Electrooculography, Evoked Potentials, Auditory, Female, Humans, Male, Memory, Middle Aged, Neuropsychological Tests, Psychiatric Status Rating Scales, Schizophrenia, Case-Control Studies
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review