The DOI matches its Crossref record; 7 of the 8 references it cites were found in a registry or an index.
Norms and standardization of the Brief Assessment of Cognition in Schizophrenia (BACS)
Abstract
According to the recommendations of the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Neurocognition Committee, one of the desired characteristics of a cognitive battery for assessing cognition in schizophrenia studies and clinical trials is the availability of normative data. This report describes normative data collected on the Brief Assessment of Cognition in Schizophrenia (BACS) from 404 healthy controls with demographic characteristics matching the 2005 United States Census of English-speakers. The six test measures demonstrated the expected pattern of correlations with age, gender, and education. Individual test scores were converted into standardized (T and z) scores and composite scores that were corrected for age and gender. An education-correction factor was calculated and recommended only for non-schizophrenia patients. Eight different verbal memory tests were found to have equivalent levels of difficulty.
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Keefe, R. (2004) · Schizophrenia Research · doi:10.1016/j.schres.2003.09.011 · Cited by 1,573
Wide Range Achievement Test-Revised
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Items 301–342 of 342
Longitudinal Improvement of Neurocognition after Electroconvulsive Therapy in Bipolar Depression
Nakano, T., Motomura, E., Hasegawa, T., Kawano, Y., & Okada, M. (2021) · Case Reports in Psychiatry · doi:10.1155/2021/7748073
An effect of cholinesterase blockade on negative symptoms in schizophrenia
Ma, M., Потанин, С. С., Rupchev, G., Burminskiy, D. S., Lepilkina, T. A., & Герович, Б. А. (2021) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro202112108137
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Pavlichenko, A. V., & Gubina, A. S. (2022) · Consortium Psychiatricum · doi:10.17816/cp105 · Cited by 1
“The tolerability and safety of various doses of cariprazine were also confirmed in the course of two non-blind trials lasting for 1 year [61] and 48 weeks [35].”
BackgroundExploración de las alteraciones de la conectividad funcional en esquizofrenia
Lorenzana, A. R. (2021) · UVaDOC UVaDOC University of Valladolid Documentary Repository (University of Valladolid) · doi:10.35376/10324/52880
Effects of Blockade of Cholinesterase on Negative Disorders in Schizophrenia
Ma, M., Потанин, С. С., Rupchev, G., Burminskiy, D. S., Lepilkina, T. A., & Герович, Б. А. (2022) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-022-01284-6
Chorazy, K. S. V., Efkemann, S. A., Schneider, U., & Juckel, G. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e11924
“Furthermore, there was a significant positive correlation between the BACS score and the PSP score.”
MethodInfluentialThe relationship between gut microbiota and schizophrenia: Recent research and treatment application
Yang, K., & Qi, J. (2023) · Highlights in Science Engineering and Technology · doi:10.54097/hset.v36i.6180
Взаимосвязь когнитивного статуса и параметров антисаккад у пациентов, страдающих шизофренией
Shvaiko, D. A., Yanushko, M. G., Шаманина, М. В., & Ivanov, M. V. (2023) · Сибирский вестник психиатрии и наркологии · doi:10.26617/1810-3111-2022-4(117)-22-32
Matsuzaki, Y., Omiya, H., Hisakura, T., Tanii, H., & Miyajima, M. (2023) · Asian Journal of Occupational Therapy · doi:10.11596/asiajot.19.205
Beño‐Ruiz‐de‐la‐Sierra, R. M., Arjona, A., Hernández-García, M., Fernández‐Linsenbarth, I., Díez, Á., Roig-Herrero, A., Osorio-Iriarte, E., & Molina, V. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4764003
Brand, B. A. (2024) · University of Groningen research database (University of Groningen / Centre for Information Technology) · doi:10.33612/diss.1087705066
Beño‐Ruiz‐de‐la‐Sierra, R. M. (2024) · UVaDOC UVaDOC University of Valladolid Documentary Repository (University of Valladolid) · doi:10.35376/10324/72377
Medvedev, V. E. (2025) · Neurology neuropsychiatry Psychosomatics · doi:10.14412/2074-2711-2025-1-24-33
Diet-Gut Microbiome Nexus: A New Paradigm in Food-Based Mental Disease Therapeutics
Anand, S., Kumar, P., Singh, S., Tiwari, S., Mishra, R., Uğuz, S., Saud, S., Mor, S. K., Yang, X., & McClements, D. J. (2025) · Food Reviews International · doi:10.1080/87559129.2025.2479123
“[160] Therefore, additional investigation and clinical studies are required to verify if modifying the gut microbiota may effectively treat this condition.”
Shmukler, A. B., & Karyakina, M. (2025) · Minerva Psychiatry · doi:10.23736/s2724-6612.24.02565-x
Ageing is associated with exaggerated overstaying in foraging behaviour
Wolpe, N., Scott, D. N., Salomon, M. L., Nassar, M. R., Fletcher, P. C., & Fernández-Egea, E. (2025) · npj Aging · doi:10.1038/s41514-025-00240-1
Synaptic density deficits in patients with a psychotic disorder and unaffected siblingsPreprint
van der Weijden-Germann, M., Jager, J. E. D., Nuninga, J. O., de Vries, E. F. J., van der Weijden, C. W. J., & Sommer, I. E. (2025) · medRxiv · doi:10.1101/2025.06.05.25328865
Stǎnicǎ, A. M., Remiszewski, N., Shen, C., Sponheim, S. R., Hellemann, G., Kraguljac, N. V., & Lee, J. (2025) · Schizophrenia Research · doi:10.1016/j.schres.2025.09.025
Koloth, A., Yeak, K., Azimi, S., Koloth, R., Alexander, A. L., Dragović, M., & John, A. P. (2025) · Australasian Psychiatry · doi:10.1177/10398562251391697
Moller, C. I., Shearman, R., & Yung, A. R. (2025) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/00048674251387882
“The BACS assesses four of the seven cognitive domains assessed by the MCCB; reasoning and problem-solving (i.e. executive functioning), processing speed, verbal memory and working memory (Keefe et al., 2008).”
Role of childhood trauma in interoception and alexithymia in schizophrenia
Narvaez, S., Wisner, K., Siatka, A., Hong, L. E., & Chiappelli, J. (2025) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2025.11.040
“Cognitive measures included the Digit Symbol Coding task of the Wechsler Adult Intelligence Scale-3 to assess processing speed (Wechsler, 1997) and the Digit Sequencing task from the Brief Assessment of Cognition in Schizophrenia (Keefe et al., 2008) to assess working memory.”
Tan, S. M. X., Lieu, M. Y., Kai, J., Yang, Z., Luke, K. K., Lwin, M. O., Lee, J., & Goh, W. W. B. (2025) · JMIR Formative Research · doi:10.2196/75960
“Cognitive performance was measured using the Brief Assessment of Cognition in Schizophrenia (BACS), which is an instrument that specifically assesses the aspects of cognition impaired and correlated with clinical outcomes in individuals with schizophrenia [54].”
Gjerde, K. V., Bartz-Johannessen, C. A., Løberg, E., Steen, V. M., Steen, N. E., Andreassen, O. A., Ueland, T., Rettenbacher, M. A., Joa, I., Reitan, S. K., et al. (2026) · Schizophrenia Research · doi:10.1016/j.schres.2026.01.021
D -optimal designs for beta binomial regression
de Vries, K., Timmerman, M. E., & Albers, C. J. (2026) · Statistical Modelling · doi:10.1177/1471082x261416637
Accelerated DMN-Targeted cTBS Improves Processing Speed Deficits in SchizophreniaPreprint
Connolly, J. G., Blyth, S. H., Yildiz, G., Rogers, B. P., Vandekar, S., Halko, M. A., Brady, R. O., & Ward, H. B. (2026) · medRxiv · doi:10.64898/2026.02.11.26346103
Does neurocognition predict personal recovery over time in psychotic disorder patients?
Rietveld, R., Kamperman, A. M., van Aken, B. C., Pijnenborg, G. H. M., & Mulder, C. L. (2026) · Schizophrenia Research Cognition · doi:10.1016/j.scog.2026.100425
“Z -scores were calculated based on both our study population, and on a general population based on the reference scores provided in the manual (Keefe et al., 2008).”
InfluentialYilmaz, D., Gottschewsky, N., Spaeth, J., Deller, L., Kara, E. B., Lada, K., Hussain, M., BrainTrain Working Group, Keeser, D., Röll, L., et al. (2026) · Research Square · doi:10.21203/rs.3.rs-9031987/v1
Harvey, P. D., & Kallestrup, P. (2026) · Journal of Visualized Experiments · doi:10.3791/70431
Self-citationPsychopathological and pathopsychological features of depressed patients at high risk of psychosis
Shulgina, D. I., Kafarov, E. R., Shishkovskaia, T. I., Rupchev, G. E., Oleychik, M. I., & Ениколопов, С. Н. (2026) · Clinical Psychology and Special Education · doi:10.17759/cpse.2026150107
Arjona, A., Conde, L. S., Beño‐Ruiz‐de‐la‐Sierra, R. M., Hernández-García, M., Fernández‐Linsenbarth, I., Díez, Á., Roig-Herrero, A., Osorio-Iriarte, E., Talavera, J. C. F., & Molina, V. (2026) · Schizophrenia Bulletin · doi:10.1093/schbul/sbag041
Collier, M. E. W., Ceeney, G., Chiappelli, J., Sathyasaikumar, K. V., Cao, T. H., Quinn, P., Ma, J., Shauriq, A., Sylvius, N. B., Hollox, E. J., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.05.19.726163
“Participants completed two cognitive measures; the digit symbol coding task, which provides a measure of processing speed [31], and the digit sequencing task, a measure of working memory [32].”
Rai, M., Wolde, H. F., & John, A. P. (2026) · Australasian Psychiatry · doi:10.1177/10398562261468928
Klein, H., Fan, R. H., Ge, T., Asgharnejad, M., Brady, C., Hanson, E., Harvey, P. D., Sedway, J., Murthy, V., Keefe, R. S. E., et al. (2026) · Schizophrenia Research · doi:10.1016/j.schres.2026.07.021
Self-citationAccelerated DMN-targeted cTBS improves processing speed deficits in schizophrenia
Connolly, J. G., Blyth, S. H., Yildiz, G., Rogers, B. P., Vandekar, S., Halko, M. A., Brady, R. O., & Ward, H. B. (2026) · Molecular Psychiatry · doi:10.1038/s41380-026-03798-8
Wahner, V. T. H., Lange, T., Stonner, I., Paribello, P., Contu, M., Pinna, M., Kopeć, D., Ferensztajn‐Rochowiak, E., Rybakowski, F., Dierssen, M., et al. (2026) · Journal of Affective Disorders · doi:10.1016/j.jad.2026.122380
Wu, F., Long, M., Li, X., Zeng, Z., Ma, S., Zhou, S., Zhang, L., Gong, H., & Huang, J. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1915709
Metabolic health in severe mental illness: bridging the mortality gap – a narrative review
Ishaq, K., Zavala, G. A., & Siddiqi, N. (2026) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000001121
Kubota, R., Izumi, S., Oba, M. S., Sanji, S., Tsuno, R., Miwa, M., Takai, K., Shima, H., & Nakagome, K. (2026) · Schizophrenia Research Cognition · doi:10.1016/j.scog.2026.100464
“Continuous variables were summarized using means and SDs. BAC App subtest scores were calculated as follows: (raw score (cid:0) age-and sex-specific mean) / age-and sex-specific SD (Keefe et al., 2008).”
Leng, A., du Sert, O. P., Lepage, M., & Ghanem, J. (2026) · Schizophrenia Research · doi:10.1016/j.schres.2026.09.033
Akiyoshi, T., Sumioka, H., Kumazaki, H., Nakanishi, J., Kato, H., & Shiomi, M. (2026) · ACM Transactions on Human-Robot Interaction · doi:10.1145/3857348
“3) Cognitive Function: The Brief Assessment of Cognition in Schizophrenia (BACS) [55] was used to assess six domains of cognitive function.”
Beño-Ruiz-de-la-Sierra, R. M., Arjona, A., Osorio-Iriarte, E., Sobrino-Conde, L., Rodríguez, V., Núñez, P., Jesus, P., Roig-Herrero, A., Diez, A., & Molina, V. (2026) · Schizophrenia Research · doi:10.1016/j.schres.2026.09.038
Metadata
- Authors
- KEEFE, R., HARVEY, P., GOLDBERG, T., GOLD, J., WALKER, T., KENNEL, C., & HAWKINS, K.
- Affiliations
- Duke University (US)
- Emory University (US)
- Zucker Hillside Hospital (US)
- Duke Medical Center (US)
- Corresponding author
- KEEFE, R
- Venue
- Schizophrenia Research
- Publisher
- Elsevier BV
- Published
- 2008-07
- Volume
- 102
- Issue
- 1-3
- Pages
- 108-115
- ISSN
- 0920-9964 (ISSN-L)
- OpenAlex
- W2018927895
- Cited by
- 342
- References
- 8
- Citations by year
- 2026: 27 · 2025: 24 · 2024: 25 · 2023: 24 · 2022: 30 · 2021: 33 · 2020: 28 · 2019: 21 · 2018: 27 · 2017: 11 · 2016: 16 · 2015: 19 · 2014: 16 · 2013: 18 · 2012: 7
- FWCI
- 3.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Schizophrenia Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Keywords
- Brief Assessment of Cognition in Schizophrenia, BACS
- MeSH terms
- Adult, Aged, Cognition Disorders, Educational Status, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Psychiatric Status Rating Scales, Psychometrics, Reference Values, Schizophrenia, Schizophrenic Psychology, Age Distribution, Sex Distribution, Control Groups, Diagnostic and Statistical Manual of Mental Disorders
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