The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Healthy lifestyle habits and 10-year cardiovascular risk in schizophrenia spectrum disorders: An analysis of the impact of smoking tobacco in the CLAMORS schizophrenia cohort
Open accessAbstract
Aim We analysed the impact of tobacco smoking over several healthy lifestyle habits along with the impact on 10-years cardiovascular event (CVE) risk in the CLAMORS schizophrenia cohort. Methods This analysis was performed within the scope of the CLAMORS study which included consecutive outpatients meeting DSM-IV criteria for schizophrenia spectrum disorder. Beside smoking history, data on usual healthy lifestyle habits included current exercise, saturated fat sparing diet, low-caloric diet, and daily dietary fibre, salt, caffeine and alcohol consumption were recorded. The 10-year CVE risk was calculated with Framingham function. Results 1704 patients (61.1% male), 18 to 74 years were examined. Prevalence of smoking was 54.54% (95% CI: 52.16%-56.90%) significantly higher than in age and sex matched general population subjects, 31.51% (31.49%-31.52%); OR=2.61 (2.37-2.87, p<0.0001). After controlling by confounders smokers showed a 10-year CVE risk excess versus non-smokers of 2.63 (2.16-3.09), p<0.001. Smoking cessation would reduce the likely of high/very high 10-year CVE risk (above 10%) by near 90% [OR=0.10 (0.06-0.18), p<0.0001]. Also, smokers were more likely to consume alcohol daily [4.13 (3.07-5.54), p<0.0001] and caffeine [3.39 (2.72-4.23), p<0.0001] than non-smoker patients with schizophrenia, and less likely to avoid daily consumption of salt [0.58 (0.43-0.78), p<0.0001], saturated fat [0.71 (0.56-0.91), p=0.006], high fibre diet [0.67 (0.53-0.84), p=0.001], or to follow a low-caloric diet [0.63 (0.48-0.81), p<0.0001]. Smokers also were less likely to do exercise habitually [0.62 (0.48-0.82, p=0.001]. Conclusion Compared with the general population, patients with schizophrenia showed significant higher prevalence of smoking. Smokers who stop smoking would benefit by a near 90% reduction in the likely of 10-year cardiovascular event risk above 10%.
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“A large study from Spain found that 55% of nearly 2,000 outpatients with schizophrenia were smokers (Bobes et al. 2010).”
From Excess early mortality in schizophrenia. (2014) · cites this paper as Bobes et al. 2010
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Cites
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Mitchell, A. J., Vancampfort, D., Sweers, K., van Winkel, R., Yu, W., & Binder, M. D. (2011) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr148 · Cited by 1,120
Excess early mortality in schizophrenia.
Laursen, T. M., Nordentoft, M., & Mortensen, P. B. (2014) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032813-153657 · Cited by 913
DE HERT, M., COHEN, D., BOBES, J., CETKOVICH‐BAKMAS, M., LEUCHT, S., NDETEI, D. M., NEWCOMER, J. W., UWAKWE, R., ASAI, I., MÖLLER, H., et al. (2011) · World Psychiatry · doi:10.1002/j.2051-5545.2011.tb00036.x · Cited by 870
Self-citationNordentoft, M., Wahlbeck, K., Hällgren, J., Westman, J., Ösby, U., Alinaghizadeh, H., Gissler, M., & Laursen, T. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055176 · Cited by 778
Bickel, W. K., Jarmolowicz, D. P., Mueller, E. T., Koffarnus, M. N., & Gatchalian, K. M. (2012) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2012.02.004 · Cited by 604
Metadata
- Authors
- Bobes, J., Arango, C., Garcia-Garcia, M., & Rejas, J.
- Affiliations
- Universidad de Oviedo (ES)
- Hospital General Universitario Gregorio Marañón (ES)
- Pfizer (Spain) (ES)
- Venue
- Schizophrenia Research
- Publisher
- Elsevier BV
- Published
- 2010-06
- Volume
- 119
- Issue
- 1-3
- Pages
- 101-109
- ISSN
- 0920-9964 (ISSN-L)
- OpenAlex
- W2152889938
- Cited by
- 181
- References
- 40
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 5 · 2023: 7 · 2022: 6 · 2021: 15 · 2020: 6 · 2019: 8 · 2018: 20 · 2017: 8 · 2016: 12 · 2015: 9 · 2014: 12 · 2013: 20 · 2012: 19
- FWCI
- 14.93
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- cc-by-nc-nd
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- Locations
- Schizophrenia Research (publishedVersion)
- PubMed (publishedVersion)
- Consultation of the Doctoral Thesis Database (TESEO) (Ministerio de Educación, Cultura y Deporte) (submittedVersion, cc-by-nc-nd)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Keywords
- schizophrenia spectrum disorders, smoking
- MeSH terms
- Cardiac Rehabilitation, Adolescent, Adult, Aged, Cardiovascular Diseases, Cross-Sectional Studies, Feeding Behavior, Female, Health Status Indicators, Health Surveys, Humans, Life Style, Male, Middle Aged, Psychotic Disorders, Risk, Schizophrenia, Schizophrenic Psychology, Smoking, Spain, Cohort Studies, Comorbidity, Case-Control Studies, Smoking Cessation, Risk Assessment, Metabolic Syndrome, Young Adult
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