Cited by 96Schizophrenia research and treatmentCounseling, Therapy, and Family DynamicsMental Health Treatment and Access

Brief culturally adapted CBT for psychosis (CaCBTp): A randomized controlled trial from a low income country

Naeem, Farooq, Saeed, Sofiya, Irfan, Muhammad, Kiran, Tayyeba, Mehmood, Nasir, Gul, Mirrat, Munshi, Tariq, Ahmad, Sohail +5 more·2015·Schizophrenia Research

Abstract

Evidence for the effectiveness of Culturally adapted CBT for psychosis in Low And Middle Income Countries (LAMIC) is limited. Therefore, brief Culturally adapted CBT for psychosis (CaCBTp) targeted at symptoms of schizophrenia for outpatients plus treatment as usual (TAU) is compared with TAU. A total of 116 participants with schizophrenia were recruited from 2 hospitals in Karachi, Pakistan, and randomized into two groups with 1:1 allocation (CaCBTp plus TAU=59, TAU=57). A brief version of CaCBTp (6 individual sessions with the involvement of main carer, plus one session for the family) was provided over 4months. Psychopathology was measured using Positive and Negative Syndrome Scale of Schizophrenia (PANSS), Psychotic Symptom Rating Scales (PSYRATS), and the Schedule for Assessment of Insight (SAI) at baseline and end of therapy. Participants in treatment group, showed statistically significant improvement in all measures of psychopathology at the end of the study compared with control group. Participants in treatment group showed statistically significant improvement in Positive Symptoms (PANSS, Positive Symptoms Subscale; p=0.000), Negative Symptoms (PANSS, Negative Symptoms subscales; p=0.000), Delusions (PSYRATS, Delusions Subscale; p=0.000), Hallucinations (PSYRATS, Hallucination Subscale; p=0.000) and Insight (SAI; p=0.007). The results suggest that brief, Culturally adapted CBT for psychosis can be an effective treatment when provided in combination with TAU, for patients with schizophrenia in a LAMIC setting. This is the first trial of CBT for psychosis from outside the western world. These findings need replicating in other low and middle income countries.

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Crossref · 10.1016/j.schres.2015.02.015

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Authors
Naeem, F., Saeed, S., Irfan, M., Kiran, T., Mehmood, N., Gul, M., Munshi, T., Ahmad, S., Kazmi, A., Husain, N., Farooq, S., Ayub, M., & Kingdon, D.
Affiliations
  • Queen's University (CA)
  • Pakistan Association of Cognitive Therapists (PK)
  • Pakistan Institute of Learning and Living (PK)
  • Sir Ganga Ram Hospital (PK)
  • Abbasi Shaheed Hospital (PK)
  • University of Manchester (GB)
  • University of Staffordshire (GB)
  • Southern Health NHS Foundation Trust (GB)
Corresponding author
Naeem, Farooq
Venue
Schizophrenia Research
Publisher
Elsevier BV
Published
2015-05
Volume
164
Issue
1-3
Pages
143-148
ISSN
0920-9964 (ISSN-L)
OpenAlex
W1972761922
Cited by
96
References
42
Citations by year
2026: 4 · 2025: 6 · 2024: 6 · 2023: 15 · 2022: 5 · 2021: 4 · 2020: 10 · 2019: 11 · 2018: 9 · 2017: 17 · 2016: 7 · 2015: 2
FWCI
9.51
Type
journal article
Language
en
Open access
closed
Locations
  • Schizophrenia Research (publishedVersion)
  • PubMed (publishedVersion)
  • ePrints Soton (University of Southampton) (acceptedVersion)
  • Research Explorer (The University of Manchester) (submittedVersion)
Funders
Pakistan Association Of Cognitive Behavior Therapists
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Psychology › Clinical Psychology › Counseling, Therapy, and Family Dynamics
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
Keywords
psychosis
MeSH terms
Adult, Aged, Delusions, Female, Hallucinations, Humans, Male, Middle Aged, Outpatients, Poverty, Psychiatric Status Rating Scales, Psychotic Disorders, Cognitive Behavioral Therapy, Treatment Outcome, Culturally Competent Care

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