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Grenni, P., Ancona, V., & Barra Caracciolo, A. (2018) · Microchemical Journal · doi:10.1016/j.microc.2017.02.006 · Cited by 1,257

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Loos, R., Gawlik, B. M., Locoro, G., Rimaviciute, E., Contini, S., & Bidoglio, G. (2009) · Environmental Pollution · doi:10.1016/j.envpol.2008.09.020 · Cited by 1,023

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Luo, Y., Xu, L., Rysz, M., Wang, Y., Zhang, H., & Alvarez, P. J. J. (2011) · Environmental Science & Technology · doi:10.1021/es104009s · Cited by 964

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Bu, Q., Wang, B., Huang, J., Deng, S., & Yu, G. (2013) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2013.08.040 · Cited by 947

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Xu, W., Zhang, G., Li, X., Zou, S., Li, P., Hu, Z., & Li, J. (2007) · Water Research · doi:10.1016/j.watres.2007.06.023 · Cited by 629

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Zou, S., Xu, W., Zhang, R., Tang, J., Chen, Y., & Zhang, G. (2011) · Environmental Pollution · doi:10.1016/j.envpol.2011.04.037 · Cited by 481

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Gulkowska, A., He, Y., So, M. K., Yeung, L. W. Y., Leung, H. W., Giesy, J. P., Lam, P. K. S., Martin, M., & Richardson, B. J. (2007) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2007.04.008 · Cited by 177

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