The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
The efficacy of cognitive-behavioral therapy for insomnia in patients with chronic pain
Open accessAbstract
Study objectives To assess the efficacy of cognitive-behavioral therapy for insomnia (CBT-I) in patients with non-malignant chronic pain.Methods Twenty-eight subjects with chronic neck and back pain were stratified according to gender, age, and ethnicity, then assigned to one of the two treatment groups: CBT-I or a contact control condition.Intervention Eight weeks of CBT-I including sleep restriction, stimulus control, sleep hygiene, and one session of cognitive therapy devoted to catastrophic thoughts about the consequences of insomnia.Measurements and results Outcomes included sleep diary assessments of sleep continuity, pre-post measures of insomnia severity (ISI), pain (Multidimensional Pain Inventory), and mood (BDI and POMS). Subjects receiving CBT-I (n=19), as compared to control subjects (n=9), exhibited significant decreases in sleep latency, wake after sleep onset, number of awakenings, and significant increase in sleep efficiency. The diary findings were paralleled by significant changes in the ISI (p=0.05). Significant improvement (p=0.03) was found on the Interference Scale of the Multidimensional Pain Inventory. The groups did not significantly differ on mood measures or measures of pain severity.Conclusions CBT-I was successfully applied to patients experiencing chronic pain. Significant improvements were found in sleep as well as in the extent to which pain interfered with daily functioning. The observed effect sizes for the sleep outcomes appear comparable to or better than meta-analytic norms for subjects with Primary Insomnia.
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“RCTs of CBT-I only, with no medication comparator condition, generally find that treatment is as efficacious in those with comorbid disorders compared to those with primary insomnia (for example see [38]).”
From Comparative effectiveness of cognitive behavioral therapy for insomnia: a systematic review (2012) · cites this paper as [38]
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Citations
Cites
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
Benjamini, Y., & Hochberg, Y. (1995) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1995.tb02031.x · Cited by 109,482 · cited 1×
“The false discovery rate (FDR) was used to effectively control for Type I errors for multiple comparisons [16].”
MethodCore outcome measures for chronic pain clinical trials: IMMPACT recommendations
Dworkin, R. H., Turk, D. C., Farrar, J. T., Haythornthwaite, J. A., Jensen, M. P., Katz, N. P., Kerns, R. D., Stucki, G., Allen, R. R., Bellamy, N., et al. (2005) · Pain · doi:10.1016/j.pain.2004.09.012 · Cited by 3,732 · cited 1×
“6 point decreases are considered clinically relevant [24,25].”
BackgroundCore outcome domains for chronic pain clinical trials: IMMPACT recommendations
Turk, D. C., Dworkin, R. H., Allen, R. R., Bellamy, N., Brandenburg, N., Carr, D. B., Cleeland, C., Dionne, R., Farrar, J. T., Galer, B. S., et al. (2003) · Pain · doi:10.1016/j.pain.2003.08.001 · Cited by 3,510
Dworkin, R. H., Turk, D. C., Wyrwich, K. W., Beaton, D., Cleeland, C. S., Farrar, J. T., Haythornthwaite, J. A., Jensen, M. P., Kerns, R. D., Ader, D. N., et al. (2008) · The Journal of Pain · doi:10.1016/j.jpain.2007.09.005 · Cited by 3,471 · cited 1×
“6 point decreases are considered clinically relevant [24,25].”
BackgroundThe West Haven-Yale Multidimensional Pain Inventory (WHYMPI)
Kerns, R. D., Turk, D. C., & Rudy, T. E. (1985) · Pain · doi:10.1016/0304-3959(85)90004-1 · Cited by 2,128 · cited 1×
“2 [10,11].”
Morley, S., Eccleston, C., & Williams, A. (1999) · Pain · doi:10.1016/s0304-3959(98)00255-3 · Cited by 1,597 · cited 1×
“In fact, our observed effects sizes on pain are comparable, if not better than the effects of cognitive-behavioral therapy for pain on pain severity [23].”
BackgroundA behavioral perspective on insomnia treatment
Spielman, A. J., Caruso, L. S., & Glovinsky, P. B. (1987) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(18)30532-x · Cited by 1,261 · cited 1×
“This point of view is further buttressed by the Spielman Model [3,4] which clearly suggests that chronic insomnia is maintained, irrespective of the original precipitants, by a common set of perpetuating factors which are largely cognitive and behavioral in nature.”
ResultComparative Meta-Analysis of Pharmacotherapy and Behavior Therapy for Persistent Insomnia
Smith, M. T., Perlis, M. L., Park, A., Smith, M. S., Pennington, J., Giles, D. E., & Buysse, D. J. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.1.5 · Cited by 863 · cited 5×
“[17] where a positive treatment response was defined as 43% improvement for SL, or 31% for NWAK, or 55% for WASO.”
BackgroundResultInfluentialSelf-citationNational Institutes of Health State of the Science Conference Statement
(2005) · Sleep · doi:10.1093/sleep/28.9.1049 · Cited by 745
The effects of sleep deprivation on pain inhibition and spontaneous pain in women
Smith, M. T., Edwards, R. R., McCann, U. D., & Haythornthwaite, J. A. (2007) · Sleep · doi:10.1093/sleep/30.4.494 · Cited by 539 · cited 1×
“It was recently demonstrated, for example, that sleep continuity disruption in healthy subjects impairs psychophysical measures of endogenous pain inhibitory capacity [20].”
BackgroundSelf-citation
Cited by
Sorted by citations
Cognitive and behavioral therapies in the treatment of insomnia: A meta-analysis
van Straten, A., van der Zweerde, T., Kleiboer, A., Cuijpers, P., Morin, C. M., & Lancee, J. (2018) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2017.02.001 · Cited by 676
Comparative effectiveness of cognitive behavioral therapy for insomnia: a systematic review
Mitchell, M. D., Gehrman, P., Perlis, M., & Umscheid, C. A. (2012) · BMC Family Practice · doi:10.1186/1471-2296-13-40 · Cited by 617
“RCTs of CBT-I only, with no medication comparator condition, generally find that treatment is as efficacious in those with comorbid disorders compared to those with primary insomnia (for example see [38]).”
BackgroundSelf-citationWu, J. Q., Appleman, E. R., Salazar, R. D., & Ong, J. C. (2015) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2015.3006 · Cited by 527
Perlis, M. L., Posner, D. A., Riemann, D. W., Bastien, C., Teel, J., & Thase, M. (2022) · The Lancet · doi:10.1016/s0140-6736(22)00879-0 · Cited by 428
Self-citationCognitive Behavioral Therapy in Persons with Comorbid Insomnia: A Meta-Analysis
Geiger-Brown, J. M., Rogers, V. E., Liu, W., Ludeman, E. M., Downton, K. D., & Diaz-Abad, M. (2015) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2014.11.007 · Cited by 331
Metadata
- Authors
- Jungquist, C. R., O’Brien, C., Matteson-Rusby, S., Smith, M. T., Pigeon, W. R., Xia, Y., Lu, N., & Perlis, M. L.
- Affiliations
- University of Rochester Medicine (US)
- Johns Hopkins University (US)
- University of Rochester (US)
- University of Pennsylvania (US)
- Venue
- Sleep Medicine
- Publisher
- Elsevier BV
- Published
- 2010-03
- Volume
- 11
- Issue
- 3
- Pages
- 302-309
- ISSN
- 1389-9457 (ISSN-L)
- PMC
- PMC2830371
- OpenAlex
- W2101759370
- Cited by
- 256
- References
- 27
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 12 · 2023: 9 · 2022: 20 · 2021: 22 · 2020: 13 · 2019: 22 · 2018: 13 · 2017: 17 · 2016: 16 · 2015: 25 · 2014: 23 · 2013: 11 · 2012: 21
- FWCI
- 20.10
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Sleep Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (L30 MH087269)
- National Institute of Nursing Research (NR5R21NR009080-02., R21NR009080)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- cognitive behavioral therapy for insomnia, chronic pain, insomnia, neck pain, back pain, sleep restriction, stimulus control, sleep hygiene, catastrophic thinking, pain interference, sleep efficiency, mood
- MeSH terms
- Adult, Female, Humans, Sleep Initiation and Maintenance Disorders, Male, Medical Records, Middle Aged, Pain, Pain Measurement, Psychiatric Status Rating Scales, Cognitive Behavioral Therapy, Single-Blind Method, Treatment Outcome
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