The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Whole tumor antigen vaccines
Open accessAbstract
Although cancer vaccines with defined antigens are commonly used, the use of whole tumor cell preparations in tumor immunotherapy is a very promising approach and can obviate some important limitations in vaccine development. Whole tumor cells are a good source of TAAs and can induce simultaneous CTLs and CD4+ T helper cell activation. We review current approaches to prepare whole tumor cell vaccines, including traditional methods of freeze-thaw lysates, tumor cells treated with ultraviolet irradiation, and RNA electroporation, along with more recent methods to increase tumor cell immunogenicity with HOCl oxidation or infection with replication-incompetent herpes simplex virus.
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Cites
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Cited by
Injectable cryogel-based whole-cell cancer vaccines
Bencherif, S. A., Warren Sands, R., Ali, O. A., Li, W. A., Lewin, S. A., Braschler, T. M., Shih, T.-Y., Verbeke, C. S., Bhatta, D., Dranoff, G., et al. (2015) · Nature Communications · doi:10.1038/ncomms8556 · Cited by 416
A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors
Wang, T., Wang, D., Yu, H., Feng, B., Zhou, F., Zhang, H., Zhou, L., Jiao, S., & Li, Y. (2018) · Nature Communications · doi:10.1038/s41467-018-03915-4 · Cited by 391
Integrating next-generation dendritic cell vaccines into the current cancer immunotherapy landscape
Garg, A. D., Coulie, P. G., Van den Eynde, B. J., & Agostinis, P. (2017) · Trends in Immunology · doi:10.1016/j.it.2017.05.006 · Cited by 340
Shi, G.-N., Zhang, C.-N., Xu, R., Niu, J.-F., Song, H.-J., Zhang, X.-Y., Wang, W.-W., Wang, Y.-M., Li, C., Wei, X.-Q., et al. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2016.10.047 · Cited by 299
Whole Tumor Antigen Vaccines: Where Are We?
Chiang, C., Coukos, G., & Kandalaft, L. (2015) · Vaccines · doi:10.3390/vaccines3020344 · Cited by 269
Self-citation
Metadata
- Authors
- Chiang, C. L.-L., Benencia, F., & Coukos, G.
- Venue
- Seminars in Immunology
- Publisher
- Elsevier BV
- Published
- 2010-06
- Volume
- 22
- Issue
- 3
- Pages
- 132-143
- ISSN
- 1044-5323 (ISSN-L)
- OpenAlex
- W2029739605
- Cited by
- 247
- References
- 12
- FWCI
- 4.10
- Type
- journal article
- Language
- en
- Open access
- bronze
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