Development of high throughput microfluidic cell culture chip for perfusion 3-dimensional cell culture-based chemosensitivity assay
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3D models can better replicate intrinsic physiological conditions and in vivo cellular responses to external stimuli compared to the 2D monolayer.
“Therefore, 3D models can better replicate intrinsic physiological conditions and in vivo cellular responses to external stimuli compared to the 2D monolayer. 77,78,80-82”
From Three-dimensional cell culture systems and their applications in drug discovery and cell-based biosensors (2014) · cites this paper as [81]
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- Authors
- Wu, M.-H., Chang, Y.-H., Liu, Y.-T., Chen, Y.-M., Wang, S.-S., Wang, H.-Y., Lai, C.-S., & Pan, T.-M.
- Affiliations
- Chang Gung University (TW)
- Corresponding author
- Wu, Min-Hsien
- Venue
- Sensors and Actuators B: Chemical
- Publisher
- Elsevier BV
- Published
- 2011-07
- Volume
- 155
- Issue
- 1
- Pages
- 397-407
- ISSN
- 0925-4005 (ISSN-L)
- OpenAlex
- W1988593504
- Cited by
- 42
- References
- 44
- Citations by year
- 2026: 1 · 2023: 3 · 2022: 1 · 2021: 2 · 2020: 4 · 2019: 3 · 2018: 2 · 2017: 5 · 2015: 4 · 2014: 2 · 2013: 5 · 2012: 9
- FWCI
- 2.84
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Sensors and Actuators B Chemical (publishedVersion)
- Funders
- Chang Gung Memorial Hospital (CMRPD190331)
- Ministry of Science and Technology, Taiwan (98-2221-E-182-008)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Microfluidic and Capillary Electrophoresis Applications
- Physical Sciences › Engineering › Biomedical Engineering › 3D Printing in Biomedical Research
- Physical Sciences › Engineering › Biomedical Engineering › Microfluidic and Bio-sensing Technologies
- Keywords
- microbioreactors, chemosensitivity assay, high-throughput screening, drug response
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