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Comparison of the incidence of cholelithiasis after sleeve gastrectomy and Roux-en-Y gastric bypass: a meta-analysis

Wan, Qianyi, Zhao, Rui, Chen, Yi, Wang, Yong, Wu, Yutao, Wu, Xiaoting·2021·Surgery for Obesity and Related Diseases
DOI 10.1016/j.soard.2021.02.003
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Abstract

Background Bariatric surgery could increase the risk of cholelithiasis, although it is unclear whether the incidence rates of cholelithiasis are similar after different bariatric procedures. Objectives To compare the incidence rates of cholelithiasis after sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) in people with obesity. Setting Meta-analysis of cohort studies. Methods We searched the PubMed and Web of Science databases for relevant studies before December 2020, and estimated the summary odds ratios (OR) and 95% confidence intervals (CI) using a random-effects model or fixed-effects model, according to the heterogeneity. Results In total, 8 cohort studies were included in this meta-analysis, and 94,855 and 106,844 participants received SG and RYGB, respectively. Compared with those receiving RYGB, the summary results showed that participants receiving SG had a 35% lower rate of cholelithiasis (OR, .65; 95% CI, .49-.86). Also, the participants receiving SG had a significantly lower incidence of cholecystectomy than those receiving RYGB (OR, .54; 95% CI, .30-.99). In a subgroup analysis, SG was associated with a significantly lower incidence of subsequent cholelithiasis than RYGB in both Western and non-Western countries. SG led to a significantly lower incidence of cholelithiasis than RYGB only when the follow-up was Conclusion Participants receiving SG had a significantly lower incidence of cholelithiasis than those receiving RYGB, particularly within the fi…

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Metadata

Authors
Wan, Q., Zhao, R., Chen, Y., Wang, Y., Wu, Y., & Wu, X.
Venue
Surgery for Obesity and Related Diseases
Publisher
Elsevier BV
Published
2021-06
Volume
17
Issue
6
Pages
1198-1205
ISSN
1550-7289
DOI
10.1016/j.soard.2021.02.003
Cited by
17
References
2
Language
en
Licence
Funders
Sichuan Province Science and Technology Support Program

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