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The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells

Esteban, Miguel Angel, Wang, Tao, Qin, Baoming, Yang, Jiayin, Qin, Dajiang, Cai, Jinglei, Li, Wen, Weng, Zhihui, Chen, Jiekai, Ni, Su, Chen, Keshi, Li, Yuan, Liu, Xiaopeng, Xu, Jianyong, Zhang, Shiqiang, Li, Feng, He, Wenzhi, Labuda, Krystyna, Song, Yancheng, Peterbauer, Anja, Wolbank, Susanne, Redl, Heinz, Zhong, Mei, Cai, Daozhang, Zeng, Lingwen, Pei, Duanqing·2010·Cell Stem Cell
DOI 10.1016/j.stem.2009.12.001
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Crossref · 10.1016/j.stem.2009.12.001

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  • Vitamin C, IL-6, TGFβ and bone morphogenetic proteins regulate cellular reprogramming by affecting DNA methylation levels, thereby adjusting the expression of certain microRNAs or facilitating the mesenchymal-to-epithelial transition (MET).

    “In addition to cell intrinsic transcription factors for cellular reprogramming, modulators such as vitamin C [62][63][64][65] , IL-6 [66][67][68] , TGFβ 69 and bone morphogenetic proteins 70 have been shown to regulate cellular reprogramming by affecting DNA methylation levels, thereby adjusting the expression of certain microRNAs or facilitating the mesenchymal-to-epithelial transition (MET).”

    From Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming (2023) · cites this paper as [62]

    The Discussion reports that vitamin C enhances reprogramming of mouse and human cells. It only proposes histone demethylation as a possible mechanism; it does not establish that vitamin C acts through DNA methylation, microRNA expression, or MET. This verdict concerns the vitamin C citations, not the separately cited modulators. (LLM, conf=0.88)

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Research works printed but not linked: 26

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  7. Kang, 2009, iPS cells can support full-term development of tetraploid blastocyst-complemented embryos, Cell Stem Cell, 5, 135, 10.1016/j.stem.2009.07.001 · DOI
  8. Kim, 2009, Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins, Cell Stem Cell, 4, 472, 10.1016/j.stem.2009.05.005 · DOI · Paper page
  9. Li, 2009, The Ink4/Arf locus is a barrier for iPS cell reprogramming, Nature, 460, 1136, 10.1038/nature08290 · DOI · Paper page
  10. Massip, 2009, Vitamin C restores healthy aging in a mouse model for Werner syndrome, FASEB J.
  11. Nakagawa, 2008, Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts, Nat. Biotechnol., 26, 101, 10.1038/nbt1374 · DOI · Paper page
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  17. Sun, 2009, Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells, Proc. Natl. Acad. Sci. USA, 106, 15720, 10.1073/pnas.0908450106 · DOI
  18. Takahashi, 2007, Induction of pluripotent stem cells from adult human fibroblasts by defined factors, Cell, 131, 861, 10.1016/j.cell.2007.11.019 · DOI · Paper page
  19. Utikal, 2009, Immortalization eliminates a roadblock during cellular reprogramming into iPS cells, Nature, 460, 1145, 10.1038/nature08285 · DOI
  20. Wernig, 2007, In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state, Nature, 448, 318, 10.1038/nature05944 · DOI
  21. Wernig, 2008, c-Myc is dispensable for direct reprogramming of mouse fibroblasts, Cell Stem Cell, 2, 10, 10.1016/j.stem.2007.12.001 · DOI
  22. Wilmut, 1997, Viable offspring derived from fetal and adult mammalian cells, Nature, 385, 810, 10.1038/385810a0 · DOI
  23. Yamanaka, 2009, A fresh look at iPS cells, Cell, 137, 13, 10.1016/j.cell.2009.03.034 · DOI · Paper page
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Metadata

Authors
Esteban, M. A., Wang, T., Qin, B., Yang, J., Qin, D., Cai, J., Li, W., Weng, Z., Chen, J., Ni, S., Chen, K., Li, Y., Liu, X., Xu, J., Zhang, S., Li, F., He, W., Labuda, K., Song, Y., Peterbauer, A., Wolbank, S., Redl, H., Zhong, M., Cai, D., Zeng, L., & Pei, D.
Venue
Cell Stem Cell
Publisher
Elsevier BV
Published
2010-01
Volume
6
Issue
1
Pages
71-79
ISSN
1934-5909
DOI
10.1016/j.stem.2009.12.001
Cited by
872
References
6
Language
en
Licence

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