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Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use
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“the feasibility of allografting without long-term immunosuppression, coupled with cryopreservation, offers an off-the-shelf approach33,47 that could facilitate the broader application of this therapy in the future.”
From Phase I trial of hES cell-derived dopaminergic neurons for Parkinson’s disease (2025) · cites this paper as [33]
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Phase I trial of hES cell-derived dopaminergic neurons for Parkinson’s disease
Tabar, V., Sarva, H., Lozano, A. M., Fasano, A., Kalia, S. K., Yu, K. K. H., Brennan, C., Ma, Y., Peng, S., Eidelberg, D., et al. (2025) · Nature · doi:10.1038/s41586-025-08845-y · Cited by 181
Self-citationDevelopment, wiring and function of dopamine neuron subtypes
Garritsen, O., van Battum, E. Y., Grossouw, L. M., & Pasterkamp, R. J. (2023) · Nature reviews. Neuroscience · doi:10.1038/s41583-022-00669-3 · Cited by 128
Metadata
- Authors
- Kim, T. W., Piao, J., Koo, S. Y., Kriks, S., Chung, S. Y., Betel, D., Socci, N. D., Choi, S. J., Zabierowski, S., Dubose, B. N., Hill, E. J., Mosharov, E. V., Irion, S., Tomishima, M. J., Tabar, V., & Studer, L.
- Venue
- Cell Stem Cell
- Publisher
- Elsevier BV
- Published
- 2021-02
- Volume
- 28
- Issue
- 2
- Pages
- 343-355.e5
- ISSN
- 1934-5909
- PMC
- PMC8006469
- Cited by
- 210
- References
- 6
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 368 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Funders
- New York State Stem Cell Science (C028503)
- National Institutes of Health
- National Cancer Institute
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