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Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use

Kim, Tae Wan, Piao, Jinghua, Koo, So Yeon, Kriks, Sonja, Chung, Sun Young, Betel, Doron, Socci, Nicholas D., Choi, Se Joon, Zabierowski, Susan, Dubose, Brittany N., Hill, Ellen J., Mosharov, Eugene V., Irion, Stefan, Tomishima, Mark J., Tabar, Viviane, Studer, Lorenz·2021·Cell Stem Cell

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Research works printed but not linked: 48

  1. Barker, 2013, Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson’s disease, Lancet Neurol., 12, 84, 10.1016/S1474-4422(12)70295-8 · DOI
  2. Barker, 2017, Human trials of stem cell-derived dopamine neurons for Parkinson’s disease: dawn of a new era, Cell Stem Cell, 21, 569, 10.1016/j.stem.2017.09.014 · DOI
  3. Blau, 2019, Stem cells in the treatment of disease, N. Engl. J. Med., 380, 1748, 10.1056/NEJMra1716145 · DOI
  4. Blauwkamp, 2012, Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors, Nat. Commun., 3, 1070, 10.1038/ncomms2064 · DOI
  5. Danielian, 1996, Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development, Nature, 383, 332, 10.1038/383332a0 · DOI
  6. Dobin, 2013, STAR: ultrafast universal RNA-seq aligner, Bioinformatics, 29, 15, 10.1093/bioinformatics/bts635 · DOI · Paper page
  7. Dodt, 2012, FLEXBAR-flexible barcode and adapter processing for next-generation sequencing platforms, Biology (Basel), 1, 895
  8. Doi, 2014, Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation, Stem Cell Reports, 2, 337, 10.1016/j.stemcr.2014.01.013 · DOI
  9. Doi, 2020, Pre-clinical study of induced pluripotent stem cell-derived dopaminergic progenitor cells for Parkinson’s disease, Nat. Commun., 11, 3369, 10.1038/s41467-020-17165-w · DOI · Paper page
  10. Durinck, 2009, Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt, Nat. Protoc., 4, 1184, 10.1038/nprot.2009.97 · DOI
  11. Fox, 2014, Stem cell therapy. Use of differentiated pluripotent stem cells as replacement therapy for treating disease, Science, 345, 1247391, 10.1126/science.1247391 · DOI
  12. Ganat, 2012, Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment, J. Clin. Invest., 122, 2928, 10.1172/JCI58767 · DOI
  13. Gantner, 2020, Viral delivery of GDNF promotes functional integration of human stem cell grafts in Parkinson’s disease, Cell Stem Cell, 26, 511, 10.1016/j.stem.2020.01.010 · DOI
  14. Grace, 1989, Morphology and electrophysiological properties of immunocytochemically identified rat dopamine neurons recorded in vitro, J. Neurosci., 9, 3463, 10.1523/JNEUROSCI.09-10-03463.1989 · DOI
  15. Harrow, 2012, GENCODE: the reference human genome annotation for The ENCODE Project, Genome Res., 22, 1760, 10.1101/gr.135350.111 · DOI · Paper page
  16. Kee, 2017, Single-cell analysis reveals a close relationship between differentiating dopamine and subthalamic nucleus neuronal lineages, Cell Stem Cell, 20, 29, 10.1016/j.stem.2016.10.003 · DOI · Paper page
  17. Kefalopoulou, 2014, Long-term clinical outcome of fetal cell transplantation for Parkinson disease: two case reports, JAMA Neurol., 71, 83, 10.1001/jamaneurol.2013.4749 · DOI
  18. Kiecker, 2001, A morphogen gradient of Wnt/beta-catenin signalling regulates anteroposterior neural patterning in Xenopus, Development, 128, 4189, 10.1242/dev.128.21.4189 · DOI
  19. Kim, 2020, Pluripotent stem cell therapies for Parkinson disease: present challenges and future opportunities, Front. Cell Dev. Biol., 8, 729, 10.3389/fcell.2020.00729 · DOI
  20. Kirkeby, 2017, Predictive markers guide differentiation to improve graft outcome in clinical translation of hESC-based therapy for Parkinson’s disease, Cell Stem Cell, 20, 135, 10.1016/j.stem.2016.09.004 · DOI
  21. Kriks, 2011, Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease, Nature, 480, 547, 10.1038/nature10648 · DOI
  22. Langmead, 2012, Fast gapped-read alignment with Bowtie 2, Nat. Methods, 9, 357, 10.1038/nmeth.1923 · DOI · Paper page
  23. Li, 2016, Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain, Proc. Natl. Acad. Sci. USA, 113, 6544, 10.1073/pnas.1605245113 · DOI · Paper page
  24. Liu, 2001, Early anterior/posterior patterning of the midbrain and cerebellum, Annu. Rev. Neurosci., 24, 869, 10.1146/annurev.neuro.24.1.869 · DOI
  25. Liu, 2003, FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors, Development, 130, 6175, 10.1242/dev.00845 · DOI
  26. Love, 2014, Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2, Genome Biol., 15, 550, 10.1186/s13059-014-0550-8 · DOI · Paper page
  27. Martinez, 1999, FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression, Development, 126, 1189, 10.1242/dev.126.6.1189 · DOI
  28. Miller et al. (2013). · DOI
  29. Nordström, 2002, Progressive induction of caudal neural character by graded Wnt signaling, Nat. Neurosci., 5, 525, 10.1038/nn0602-854 · DOI
  30. Nouri, 2017, A novel floor plate boundary defined by adjacent En1 and Dbx1 microdomains distinguishes midbrain dopamine and hypothalamic neurons, Development, 144, 916
  31. Parmar, 2020, The future of stem cell therapies for Parkinson disease, Nat. Rev. Neurosci., 21, 103, 10.1038/s41583-019-0257-7 · DOI
  32. Piao, 2021, Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01, Cell Stem Cell, 28, 10.1016/j.stem.2021.01.004 · DOI · Paper page
  33. Politis, 2010, Serotonergic neurons mediate dyskinesia side effects in Parkinson’s patients with neural transplants, Sci. Transl. Med., 2, 38ra46, 10.1126/scitranslmed.3000976 · DOI
  34. Pothos, 1996, L-3,4-dihydroxyphenylalanine increases the quantal size of exocytotic dopamine release in vitro, J. Neurochem., 66, 629, 10.1046/j.1471-4159.1996.66020629.x · DOI
  35. Poulin, 2020, Classification of midbrain dopamine neurons using single-cell gene expression profiling approaches, Trends Neurosci., 43, 155, 10.1016/j.tins.2020.01.004 · DOI · Paper page
  36. Rayport, 1992, Identified postnatal mesolimbic dopamine neurons in culture: morphology and electrophysiology, J. Neurosci., 12, 4264, 10.1523/JNEUROSCI.12-11-04264.1992 · DOI
  37. Rekaik, 2015, Dissecting the role of Engrailed in adult dopaminergic neurons--Insights into Parkinson disease pathogenesis, FEBS Lett., 589, 3786, 10.1016/j.febslet.2015.10.002 · DOI
  38. Robinson, 2011, Integrative genomics viewer, Nat. Biotechnol., 29, 24, 10.1038/nbt.1754 · DOI · Paper page
  39. Simon, 2001, Fate of midbrain dopaminergic neurons controlled by the engrailed genes, J. Neurosci., 21, 3126, 10.1523/JNEUROSCI.21-09-03126.2001 · DOI
  40. Sundberg, 2013, Improved cell therapy protocols for Parkinson’s disease based on differentiation efficiency and safety of hESC-, hiPSC-, and non-human primate iPSC-derived dopaminergic neurons, Stem Cells, 31, 1548, 10.1002/stem.1415 · DOI
  41. Tabar, 2014, Pluripotent stem cells in regenerative medicine: challenges and recent progress, Nat. Rev. Genet., 15, 82, 10.1038/nrg3563 · DOI
  42. Temple, 2017, Lessons learned from pioneering neural stem cell studies, Stem Cell Reports, 8, 191, 10.1016/j.stemcr.2017.01.024 · DOI · Paper page
  43. Tiklová, 2020, Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease, Nat. Commun., 11, 2434, 10.1038/s41467-020-16225-5 · DOI
  44. Xi, 2012, Specification of midbrain dopamine neurons from primate pluripotent stem cells, Stem Cells, 30, 1655, 10.1002/stem.1152 · DOI
  45. Xiong, 2021, Human stem cell-derived neurons repair circuits and restore neural function, Cell Stem Cell, 28, 112, 10.1016/j.stem.2020.08.014 · DOI
  46. Yan, 2005, Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells, Stem Cells, 23, 781, 10.1634/stemcells.2004-0365 · DOI
  47. Ye, 2001, Distinct regulators control the expression of the mid-hindbrain organizer signal FGF8, Nat. Neurosci., 4, 1175, 10.1038/nn761 · DOI
  48. Zhang, 2008, Model-based analysis of ChIP-Seq (MACS), Genome Biol., 9, R137, 10.1186/gb-2008-9-9-r137 · DOI · Paper page

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Metadata

Authors
Kim, T. W., Piao, J., Koo, S. Y., Kriks, S., Chung, S. Y., Betel, D., Socci, N. D., Choi, S. J., Zabierowski, S., Dubose, B. N., Hill, E. J., Mosharov, E. V., Irion, S., Tomishima, M. J., Tabar, V., & Studer, L.
Venue
Cell Stem Cell
Publisher
Elsevier BV
Published
2021-02
Volume
28
Issue
2
Pages
343-355.e5
ISSN
1934-5909
Cited by
210
References
6
Language
en
Funders
  • New York State Stem Cell Science (C028503)
  • National Institutes of Health
  • National Cancer Institute

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