The DOI matches its Crossref record; 52 of the 53 references it cites were found in a registry or an index.
Green improved processes to extract bioactive phenolic compounds from brown macroalgae using Sargassum muticum as model
Abstract
A comparative study between "alternative" extraction processes such as centrifugal partition extraction (CPE), supercritical fluid extraction (SFE) and pressurized liquid extraction (PLE) and classical solid/liquid used in the laboratory are currently focusing on the efficiency (selectivity and productivity) to obtain bioactive phenolic compounds from the phaeophyte Sargassum muticum model. The choice of the best process was based on several measurements: (i) the total phenolic content measured by the colorimetric Folin-Ciocalteu assay, (ii) radical scavenger and antioxidant activities assessed by the DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging assay, and the β-carotene bleaching method and finally (iii) the method productivity. Irrespective of the solvent used in the processes, alternative methods are always sharply more effective than classical ones. With the exception of SFE which does not allow extracting the totality of the active phenolic compounds, two of the other extraction methods were particularly promising. First, CPE afforded the most important yields in concentrated phenolic compounds (PC) (22.90±0.65% DW) also displaying the best activities (0.52±0.02 and 0.58±0.19 mg/mL for IC50 and AAC700, respectively). Secondly, PLE using an EtOH:water mixture 75:25 (v/v) allowed a good PC extraction (10.18±0.25% DW) with huge efficiency. Despite a lesser activity of the extracts (0.77±0.01 and 1.59±0.15 mg/mL for IC50 and AAC700, respectively) PLE is a green process and potentially complies European norms requirements for the prospective valorization of phenolic compounds from S. muticum in Brittany.
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In the citing paper
“Besides, macroalgae species as well as the season of their collecting affects phenolics extraction. It is important to collect macroalgae during the summer [36] because then they produce the maximum of phenolic compounds.”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [36]
In the citing paper
“According to published studies [14,31,36], this is the most promising technique for the extraction of bioactive compounds.”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [36]
Citations
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Cited by
Sorted by citations
Application of Novel Extraction Technologies for Bioactives from Marine Algae
Kadam, S. U., Tiwari, B. K., & O’Donnell, C. P. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf400819p · Cited by 547
Herrero, M., Sánchez‐Camargo, A. D. P., Cifuentes, A., & Ibáñez, E. (2015) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2015.01.018 · Cited by 344
Li, Y., Fu, X., Duan, D., Liu, X., Xu, J., & Gao, X. (2017) · Marine Drugs · doi:10.3390/md15020049 · Cited by 272
Alternative and efficient extraction methods for marine-derived compounds
Grosso, C., Valentão, P., Ferreres, F., & Andrade, P. (2015) · Marine Drugs · doi:10.3390/md13053182 · Cited by 248
Golden Tides: Problem or Golden Opportunity? The Valorisation of Sargassum from Beach Inundations
Milledge, J. J., & Harvey, P. J. (2016) · Journal of Marine Science and Engineering · doi:10.3390/jmse4030060 · Cited by 249
Metadata
- Authors
- Anaëlle, T., Serrano Leon, E., Laurent, V., Elena, I., Mendiola, J. A., Stéphane, C., Nelly, K., Stéphane, L. B., Luc, M., & Valérie, S.-P.
- Affiliations
- Instituto de Investigación en Ciencias de la Alimentación (ES)
- ORCID
- Mendiola, Jose A.
- Venue
- Talanta
- Publisher
- Elsevier BV
- Published
- 2013-01
- Volume
- 104
- Pages
- 44-52
- ISSN
- 0039-9140 (ISSN-L)
- OpenAlex
- W2008473817
- Cited by
- 121
- References
- 53
- Citations by year
- 2026: 6 · 2025: 9 · 2024: 10 · 2023: 9 · 2022: 5 · 2021: 11 · 2020: 11 · 2019: 7 · 2018: 12 · 2017: 9 · 2016: 9 · 2015: 13 · 2014: 8 · 2013: 2
- FWCI
- 10.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Talanta (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion)
- Funders
- Ministère de l'Education Nationale, de l'Enseignement Supérieur et de Recherche
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
- Keywords
- Sargassum muticum, brown macroalgae, phenolic compounds, extraction methods, supercritical fluid extraction, accelerated solvent extraction, green extraction, antioxidant activity, free radical scavenging, total phenolic content
- MeSH terms
- Antioxidants, Biphenyl Compounds, Magnetic Resonance Spectroscopy, Phenols, Picrates, Plant Extracts, beta Carotene, Sargassum, Green Chemistry Technology
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