Cited by 121Seaweed-derived Bioactive CompoundsPhytochemicals and Antioxidant ActivitiesAgricultural and Biological Research

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Green improved processes to extract bioactive phenolic compounds from brown macroalgae using Sargassum muticum as model

Anaëlle, Tanniou, Serrano Leon, Esteban, Laurent, Vandanjon, Elena, Ibanez, Mendiola, Jose A., Stéphane, Cerantola, Nelly, Kervarec, Stéphane, La Barre, Luc, Marchal, Valérie, Stiger-Pouvreau·2013·Talanta

DOI 10.1016/j.talanta.2012.10.088

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Abstract

A comparative study between "alternative" extraction processes such as centrifugal partition extraction (CPE), supercritical fluid extraction (SFE) and pressurized liquid extraction (PLE) and classical solid/liquid used in the laboratory are currently focusing on the efficiency (selectivity and productivity) to obtain bioactive phenolic compounds from the phaeophyte Sargassum muticum model. The choice of the best process was based on several measurements: (i) the total phenolic content measured by the colorimetric Folin-Ciocalteu assay, (ii) radical scavenger and antioxidant activities assessed by the DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging assay, and the β-carotene bleaching method and finally (iii) the method productivity. Irrespective of the solvent used in the processes, alternative methods are always sharply more effective than classical ones. With the exception of SFE which does not allow extracting the totality of the active phenolic compounds, two of the other extraction methods were particularly promising. First, CPE afforded the most important yields in concentrated phenolic compounds (PC) (22.90±0.65% DW) also displaying the best activities (0.52±0.02 and 0.58±0.19 mg/mL for IC50 and AAC700, respectively). Secondly, PLE using an EtOH:water mixture 75:25 (v/v) allowed a good PC extraction (10.18±0.25% DW) with huge efficiency. Despite a lesser activity of the extracts (0.77±0.01 and 1.59±0.15 mg/mL for IC50 and AAC700, respectively) PLE is a green process and potentially complies European norms requirements for the prospective valorization of phenolic compounds from S. muticum in Brittany.

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Self-citation

Authors: Anaëlle, T., Serrano Leon, E., Laurent, V., Elena, I., Mendiola, J. A., Stéphane, C., Nelly, K., Stéphane, L. B., Luc, M., & Valérie, S.-P.
Affiliations: Instituto de Investigación en Ciencias de la Alimentación (ES)
ORCID: Mendiola, Jose A.
Venue: Talanta
Publisher: Elsevier BV
Published: 2013-01
Volume: 104
Pages: 44-52
ISSN: 0039-9140 (ISSN-L)
DOI: 10.1016/j.talanta.2012.10.088
OpenAlex: W2008473817
Cited by: 121
References: 53
Citations by year: 2026: 6 · 2025: 9 · 2024: 10 · 2023: 9 · 2022: 5 · 2021: 11 · 2020: 11 · 2019: 7 · 2018: 12 · 2017: 9 · 2016: 9 · 2015: 13 · 2014: 8 · 2013: 2
FWCI: 10.77
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Talanta (publishedVersion)
PubMed (publishedVersion)
HAL (submittedVersion)
DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion)
Funders: Ministère de l'Education Nationale, de l'Enseignement Supérieur et de Recherche
Topics: Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
Keywords: Sargassum muticum, brown macroalgae, phenolic compounds, extraction methods, supercritical fluid extraction, accelerated solvent extraction, green extraction, antioxidant activity, free radical scavenging, total phenolic content
MeSH terms: Antioxidants, Biphenyl Compounds, Magnetic Resonance Spectroscopy, Phenols, Picrates, Plant Extracts, beta Carotene, Sargassum, Green Chemistry Technology

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Green improved processes to extract bioactive phenolic compounds from brown macroalgae using Sargassum muticum as model

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