Cited by 833Immune cells in cancerCytokine Signaling Pathways and InteractionsPhagocytosis and Immune Regulation

The DOI matches its Crossref record; 96 of the 98 references it cites were found in a registry or an index.

CSF-1 regulation of the wandering macrophage: complexity in action

Pixley, Fiona J., Stanley, E. Richard·2004·Trends in Cell Biology

DOI 10.1016/j.tcb.2004.09.016

Open this paper in CoChat — free account

Abstract

Most tissue macrophages and osteoclasts are regulated by colony-stimulating factor-1 (CSF-1, also known as macrophage CSF). The effects of CSF-1 are mediated by the CSF-1 receptor tyrosine kinase (CSF-1R), through autophosphorylation of CSF-1R and the subsequent phosphorylation of downstream molecules. Triggering this phosphorylation cascade increases gene transcription and protein translation, and induces cytoskeletal remodeling by several signaling pathways, leading to the survival, proliferation and differentiation of target cells. CSF-1-regulated tissue macrophages are important for innate immunity and for tissue development and function. Because CSF-1 regulates the survival, proliferation and chemotaxis of macrophages and supports their activation, this factor is involved in the pathogenesis of several diseases.

Integrity signals

Registry

Crossref · 10.1016/j.tcb.2004.09.016

Cites

96 of 96 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Rho GTPases in cell biology
Etienne-Manneville, S., & Hall, A. (2002) · Nature · doi:10.1038/nature01148 · Cited by 4,965
Rho and Rac Take Center Stage
Burridge, K., & Wennerberg, K. (2004) · Cell · doi:10.1016/s0092-8674(04)00003-0 · Cited by 1,831
Obesity-induced inflammatory changes in adipose tissue
Wellen, K. E., & Hotamisligil, G. S. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200320514 · Cited by 1,823
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene
Yoshida, H., Hayashi, S.-I., Kunisada, T., Ogawa, M., Nishikawa, S., Okamura, H., Sudo, T., Shultz, L. D., & Nishikawa, S.-I. (1990) · Nature · doi:10.1038/345442a0 · Cited by 1,789
Genetic regulation of osteoclast development and function
Teitelbaum, S. L., & Ross, F. P. (2003) · Nature Reviews Genetics · doi:10.1038/nrg1122 · Cited by 1,720
Colony-Stimulating Factor 1 Promotes Progression of Mammary Tumors to Malignancy
Lin, E. Y., Nguyen, A. V., Russell, R. G., & Pollard, J. W. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.193.6.727 · Cited by 1,594
Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects
Dai, X.-M., Ryan, G. R., Hapel, A. J., Dominguez, M. G., Russell, R. G., Kapp, S., Sylvestre, V., & Stanley, E. R. (2002) · Blood · doi:10.1182/blood.v99.1.111 · Cited by 1,184
Self-citation
Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse.
Wiktor-Jedrzejczak, W., Bartocci, A., Ferrante, A. W., Ahmed-Ansari, A., Sell, K. W., Pollard, J. W., & Stanley, E. R. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.12.4828 · Cited by 1,031
Self-citation
Involvement of Granulocyte-Macrophage Colony-Stimulating Factor in Pulmonary Homeostasis
Dranoff, G., Crawford, A. D., Sadelain, M., Neugeboren, B. I., Rashid, A., Bronson, R. T., Dickersin, G. R., Bachurski, C. J., Mark, E. L., Whitsett, J. A., et al. (1994) · Science · doi:10.1126/science.8171324 · Cited by 877
Divergent Signals and Cytoskeletal Assemblies Regulate Self-Organizing Polarity in Neutrophils
Xu, J., Wang, F., Keymeulen, A. V., Herzmark, P., Straight, A. F., Kelly, K., Takuwa, Y., Sugimoto, N., Mitchison, T. J., & Bourne, H. R. (2003) · Cell · doi:10.1016/s0092-8674(03)00555-5 · Cited by 684

Flagged first, then by citations

Show all 98 references

2 of the 98 references couldn’t be matched to a known paper.

Sorted by citations

Items 301–400 of 833

The RUNX1/IL-34/CSF-1R axis is an autocrinally regulated modulator of resistance to BRAF-V600E inhibition in melanoma
Giricz, O., Mo, Y., Dahlman, K. B., Cotto-Rios, X. M., Vardabasso, C., Nguyen, H., Matusow, B., Bartenstein, M., Polishchuk, V., Johnson, D. B., et al. (2018) · JCI Insight · doi:10.1172/jci.insight.120422 · Cited by 40
Self-citation
CSF-1R Signaling in Health and Disease: A Focus on the Mammary Gland
Dwyer, A. R., & Pixley, F. J. (2014) · Journal of Mammary Gland Biology and Neoplasia · doi:10.1007/s10911-014-9320-1 · Cited by 40
Self-citation
Potential of Photodynamic Therapy Based on Sugar-Conjugated Photosensitizers
Kataoka, H., Nishie, H., Tanaka, M., Sasaki, M., Nomoto, A., Osaki, T., Okamoto, Y., & Yano, S. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10040841 · Cited by 41
LynA regulates an inflammation-sensitive signaling checkpoint in macrophages
Freedman, T. S., Tan, Y. X., Skrzypczynska, K. M., Manz, B. N., Sjaastad, F. V., Goodridge, H. S., Lowell, C. A., & Weiss, A. (2015) · eLife · doi:10.7554/elife.09183 · Cited by 36
The Mechanism of CSF-1-induced Wiskott-Aldrich Syndrome Protein Activation in Vivo
Cammer, M., Gevrey, J., Lorenz, M., Dovas, A., Condeelis, J. S., & Cox, D. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.036384 · Cited by 39
Novel associations between inflammation-related proteins and adiposity: A targeted proteomics approach across four population-based studies
Ponce-de-Leon, M., Linseisen, J., Peters, A., Linkohr, B., Heier, M., Grallert, H., Schöttker, B., Trares, K., Bhardwaj, M., Gao, X. Y., et al. (2021) · Translational research · doi:10.1016/j.trsl.2021.11.004 · Cited by 41
Polymorphisms of pro‐inflammatory cytokine genes and the risk for acute suppurative or chronic nonsuppurative apical periodontitis in a C olombian population
Amaya, M. P., Criado, L. Y., Fuentes, B. Y. B., Gómez, M., Torres, O., Flórez, L. T., González, C. I., & Flórez-Vargas, O. (2012) · International Endodontic Journal · doi:10.1111/j.1365-2591.2012.02097.x · Cited by 39
Macrophage-modulating cytokines predict adverse outcome in heart failure
Hohensinner, P. J., Rychli, K., Zorn, G., Hülsmann, M., Berger, R., Mörtl, D., Richter, B., Huber, K., Wojta, J., Niessner, A., et al. (2010) · Thrombosis and Haemostasis · doi:10.1160/th09-06-0399 · Cited by 40
Macrophages in neuroinflammation: role of the renin-angiotensin-system
Hammer, A., Stegbauer, J., & Linker, R. A. (2017) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-017-1942-x · Cited by 40
Macrophage colony stimulating factor expression in human cardiac cells is upregulated by tumor necrosis factor‐α via an NF‐κB dependent mechanism
Hohensinner, P. J., Kaun, C., Rychli, K., Niessner, A., Pfaffenberger, S., Rega‐Kaun, G., de Martin, R., Maurer, G., Ullrich, R., Huber, K., et al. (2007) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2007.02784.x · Cited by 38
Regulation of tyrosine phosphorylation in macrophage phagocytosis and chemotaxis
Park, H., Ishihara, D., & Cox, D. (2011) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2011.02.019 · Cited by 38
Lipid Rafts and Redox Regulation of Cellular Signaling in Cholesterol Induced Atherosclerosis
Catalgol, B., & Özer, N. K. (2010) · Current Cardiology Reviews · doi:10.2174/157340310793566181 · Cited by 37
Colony-stimulating factor-1 and colony-stimulating factor-1 receptor co-expression is associated with disease progression in gastric cancer
Okugawa, Y., Toiyama, Y., Ichikawa, T., Kawamura, M., Yasuda, H., Fujikawa, H., Saigusa, S., Ohi, M., Araki, T., Tanaka, K., et al. (2018) · International Journal of Oncology · doi:10.3892/ijo.2018.4406 · Cited by 38
Mesothelial cell CSF1 sustains peritoneal macrophage proliferation
Ivanov, S., Gallerand, A., Gros, M., Stunault, M. I., Merlin, J., Vaillant, N., Yvan‐Charvet, L., & Guinamard, R. (2019) · European Journal of Immunology · doi:10.1002/eji.201948164 · Cited by 38
High‐grade mesenchymal pancreatic ductal adenocarcinoma drives stromal deactivation through CSF‐1
Steins, A., van Mackelenbergh, M. G., van der Zalm, A. P., Klaassen, R., Serrels, B., Goris, S. G., Kocher, H. M., Waasdorp, C., de Jong, J. H., Tekin, C., et al. (2020) · EMBO Reports · doi:10.15252/embr.201948780 · Cited by 38
An Early Microglial Response Is Needed To Efficiently Control Herpes Simplex Virus Encephalitis
Uyar, O., Laflamme, N., Piret, J., Venable, M.-C., Carbonneau, J., Zarrouk, K., Rivest, S., & Boivin, G. (2020) · Journal of Virology · doi:10.1128/jvi.01428-20 · Cited by 36
Pubertal mammary gland development is a key determinant of adult mammographic density
Ghadge, A. G., Dasari, P., Stone, J., Thompson, E. W., Robker, R. L., & Ingman, W. V. (2020) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2020.11.011 · Cited by 38
Cell Trafficking at the Intersection of the Tumor–Immune Compartments
Du, W., Nair, P. R., Johnston, A. C., Wu, P., & Wirtz, D. (2022) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-110320-110749 · Cited by 38
CSF-1 receptor signalling from endosomes mediates the sustained activation of Erk1/2 and Akt in macrophages
Huynh, J., Kwa, M. Q., Cook, A. D., Hamilton, J. A., & Scholz, G. M. (2012) · Cellular Signalling · doi:10.1016/j.cellsig.2012.04.022 · Cited by 36
Mitogen-Activated Protein Kinases and Mitogen Kinase Phosphatase 1: A Critical Interplay in Macrophage Biology
Lloberas, J., Estrella, L. V., Tur, J., Vico, T., & Celada, A. (2016) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2016.00028 · Cited by 37
From HDLS to BANDDOS: fast-expanding phenotypic spectrum of disorders caused by mutations in CSF1R
Guo, L. Z., & Ikegawa, S. (2021) · Journal of Human Genetics · doi:10.1038/s10038-021-00942-w · Cited by 35
The RNA-binding protein QKI5 is a direct target of C/EBPα and delays macrophage differentiation
Fu, H., Yang, G., Wei, M., Liu, L., Jin, L., Lu, X., Wang, L., Shen, L., Zhang, J., Lu, H., et al. (2012) · Molecular Biology of the Cell · doi:10.1091/mbc.e11-05-0412 · Cited by 40
Regulation of macrophage motility by Irgm1
Henry, S. C., Traver, M. K., Daniell, X., Indaram, M., Oliver, T., & Taylor, G. A. (2009) · Journal of Leukocyte Biology · doi:10.1189/jlb.0509299 · Cited by 37
Distinct Activities of Stromal Cells Involved in the Organogenesis of Lymph Nodes and Peyer’s Patches
Okuda, M., Togawa, A., Wada, H., & Nishikawa, S. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.2.804 · Cited by 37
Discovery of Novel Benzopyranyl Tetracycles that Act as Inhibitors of Osteoclastogenesis Induced by Receptor Activator of NF-κB Ligand
Zhu, M., Kim, M. H., Lee, S., Bae, S. J., Kim, S. H., & Park, S. B. (2010) · Journal of Medicinal Chemistry · doi:10.1021/jm1011269 · Cited by 37
CSF1R Protein Expression in Reactive Lymphoid Tissues and Lymphoma: Its Relevance in Classical Hodgkin Lymphoma
Martín-Moreno, A. M., Roncador, G., Maestre, L., Mata, E., Jiménez, S., Martinez-Torrecuadrada, J. L., Reyes-García, A. I., Rubio, C., Tomás, J. F., Estévez, M., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0125203 · Cited by 38
Biomarkers for Kidney Involvement in Pediatric Lupus
Goilav, B., Putterman, C., & Rubinstein, T. B. (2015) · Biomarkers in Medicine · doi:10.2217/bmm.15.25 · Cited by 36
MKP ‐1: A critical phosphatase in the biology of macrophages controlling the switch between proliferation and activation
Comalada, M., Lloberas, J., & Celada, A. (2012) · European Journal of Immunology · doi:10.1002/eji.201242441 · Cited by 36
Delivery of the CSF-1R to the lumen of macropinosomes promotes its destruction in macrophages
Lou, J., Low-Nam, S. T., Kerkvliet, J. G., & Hoppe, A. D. (2014) · Journal of Cell Science · doi:10.1242/jcs.154393 · Cited by 36
Differential prognostic impact of interleukin-34 mRNA expression and infiltrating immune cell composition in intrinsic breast cancer subtypes
Zins, K., Heller, G., Mayerhofer, M., Schreiber, M., & Abraham, D. (2018) · Oncotarget · doi:10.18632/oncotarget.25226 · Cited by 36
CSF1R Is Required for Differentiation and Migration of Langerhans Cells and Langerhans Cell Histiocytosis
Lonardi, S., Scutera, S., Licini, S., Lorenzi, L., Cesinaro, A. M., Gatta, L. B., Castagnoli, C., Bollero, D., Sparti, R., Tomaselli, M., et al. (2020) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-19-0232 · Cited by 35
FMS Kinase Inhibitors: Current Status and Future Prospects
El-Gamal, M. I., Anbar, H. S., Yoo, K. H., & Oh, C. (2012) · Medicinal Research Reviews · doi:10.1002/med.21258 · Cited by 37
The interferon-inducible gene, Ifi204, is transcriptionally activated in response to M-CSF, and its expression favors macrophage differentiation in myeloid progenitor cells
Jeremy, D., Mouchiroud, G., & Bourette, R. P. (2005) · Journal of Leukocyte Biology · doi:10.1189/jlb.0205083 · Cited by 36
Specific inhibition of PI 3 K p110δ inhibits CSF ‐1‐induced macrophage spreading and invasive capacity
Mouchemore, K. A., Sampaio, N. G., Murrey, M. W., Stanley, E. R., Lannutti, B. J., & Pixley, F. J. (2013) · FEBS Journal · doi:10.1111/febs.12316 · Cited by 36
Self-citation
Spontaneous and induced osteoclastogenic behaviour of human peripheral blood mononuclear cells and their CD14+ and CD14− cell fractions
Costa‐Rodrigues, J., Fernandes, A. C., & Fernandes, M. H. (2011) · Cell Proliferation · doi:10.1111/j.1365-2184.2011.00768.x · Cited by 36
Phosphatidylinostitol-3 kinase and phospholipase C enhance CSF-1-dependent macrophage survival by controlling glucose uptake
Chang, M., Hamilton, J. A., Scholz, G. M., Masendycz, P. J., Macaulay, S. L., & Elsegood, C. L. (2009) · Cellular Signalling · doi:10.1016/j.cellsig.2009.04.003 · Cited by 39
Rab10-CAV1 mediated intraluminal vesicle transport to migrasomes
Li, Y., Wen, Y., Li, Y., Tan, X., Gao, S., Fan, P., Tian, W., Wong, C. C. L., & Chen, Y. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2319267121 · Cited by 35
Prostaglandin E2 transactivates the colony‐stimulating factor‐1 receptor and synergizes with colony‐stimulating factor‐1 in the induction of macrophage migration via the mitogen‐activated protein kinase ERK1/2
Digiacomo, G., Ziche, M., Sbarba, P. D., Donnini, S., & Rovida, E. (2015) · The FASEB Journal · doi:10.1096/fj.14-258939 · Cited by 35
Genome Sequence of Peacock Reveals the Peculiar Case of a Glittering Bird
Jaiswal, S. K., Gupta, A., Saxena, R., K., V., Sharma, A. K., Mittal, P., Roy, A., Shafer, A. B. A., Vijay, N., & Sharma, V. K. (2018) · Frontiers in Genetics · doi:10.3389/fgene.2018.00392 · Cited by 31
Acute inflammatory response in the skin of gilthead seabream (Sparus aurata) caused by carrageenin
Campos‐Sánchez, J. C., Mayor-Lafuente, J., González‐Silvera, D., Guardiola, F. A., & Esteban, M. Á. (2021) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2021.10.009 · Cited by 35
Phosphoinositide 3-kinase/Akt and its related signaling pathways in the regulation of tumor-associated macrophages polarization
Yang, D., Yang, L., Cai, J., Li, H., Zheng, X., & Hou, Y. (2022) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-022-04461-w · Cited by 34
The Primary Microglial Leukodystrophies: A Review
Ferrer, I. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23116341 · Cited by 35
Novel LCK/FMS inhibitors based on phenoxypyrimidine scaffold as potential treatment for inflammatory disorders
Farag, A. K., Elkamhawy, A., Londhe, A. M., Lee, K., Pae, A. N., & Roh, E. J. (2017) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2017.10.003 · Cited by 34
Inhibition of differentiation of monocyte to macrophages in atherosclerosis by oligomeric proanthocyanidins –In-vivo and in-vitro study
Mohana, T., Vijayan, N. A., Jamuna, S., Sadullah, M. S. S., & Devaraj, S. N. (2015) · Food and Chemical Toxicology · doi:10.1016/j.fct.2015.04.028 · Cited by 34
Neutrophil and Macrophage Cell Surface Colony-Stimulating Factor 1 Shed by ADAM17 Drives Mouse Macrophage Proliferation in Acute and Chronic Inflammation
Tang, J., Frey, J. M., Wilson, C. L., Moncada-Pazos, Á., Levet, C., Freeman, M., Rosenfeld, M. E., Stanley, E. R., Raines, E. W., & Bornfeldt, K. (2018) · Molecular and Cellular Biology · doi:10.1128/mcb.00103-18 · Cited by 35
Self-citation
Myelodysplastic Syndromes: Clinicopathologic Features, Pathobiology, and Molecular Pathogenesis
Nishino, H., & Chang, C.-C. (2005) · Archives of Pathology & Laboratory Medicine · doi:10.5858/2005-129-1299-mscfpa · Cited by 34
Small-molecule amines: a big role in the regulation of bone homeostasis
Zhang, Q., Yang, J., Hu, N., Liu, J., Yu, H., Pan, H., Chen, D., & Ruan, C. (2023) · Bone Research · doi:10.1038/s41413-023-00262-z · Cited by 34
Contribution of macrophage polarization in bone metabolism: A literature review
Yan, Q., Liu, H., Zhu, R., & Zhang, Z. (2024) · Cytokine · doi:10.1016/j.cyto.2024.156768 · Cited by 35
SECTM1 Produced by Tumor Cells Attracts Human Monocytes via CD7-Mediated Activation of the PI3K Pathway
Wang, T., Ge, Y., Xiao, M., López-Coral, A., Li, L., Roesch, A., Huang, C., Alexander, P. M., VOGT, T. M., Xu, X., et al. (2013) · Journal of Investigative Dermatology · doi:10.1038/jid.2013.437 · Cited by 33
A genome-wide association study of fetal response to type 2 porcine reproductive and respiratory syndrome virus challenge
Yang, T., Wilkinson, J., Wang, Z., Ladinig, A., Harding, J. C. S., & Plastow, G. S. (2016) · Scientific Reports · doi:10.1038/srep20305 · Cited by 33
Contribution of Macrophages and T Cells in Skeletal Metastasis
Mendoza‐Reinoso, V., McCauley, L. K., & Fournier, P. G. J. (2020) · Cancers · doi:10.3390/cancers12041014 · Cited by 35
Optimization of a Potent Class of Arylamide Colony-Stimulating Factor-1 Receptor Inhibitors Leading to Anti-inflammatory Clinical Candidate 4-Cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[(dimethylamino)acetyl]-4-piperidinyl]phenyl]-1H-imidazole-2-carboxamide (JNJ-28312141)
Illig, C. R., Manthey, C. L., Wall, M. J., Meegalla, S. K., Chen, J., Wilson, K. J., Ballentine, S. K., DesJarlais, R. L., Schubert, C. J., Crysler, C. S., et al. (2011) · Journal of Medicinal Chemistry · doi:10.1021/jm200900q · Cited by 33
Chromatin-associated CSF-1R binds to the promoter of proliferation-related genes in breast cancer cells
Barbetti, V., Morandi, A., Tusa, I., Digiacomo, G., Riverso, M., Marzi, I., Cipolleschi, M. G., Bessi, S., Giannini, A., Leo, A. D., et al. (2013) · Oncogene · doi:10.1038/onc.2013.542 · Cited by 33
Colony-stimulating factor-1 receptor protein expression is a specific marker for goldfish (Carassius auratus L.) macrophage progenitors and their differentiated cell types
Katzenback, B. A., & Belosevic, M. (2011) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2011.12.003 · Cited by 33
Transgenic expression of CSF-1 in CSF-1 receptor-expressing cells leads to macrophage activation, osteoporosis, and early death
Wei, S., Dai, X.-M., & Stanley, E. R. (2006) · Journal of Leukocyte Biology · doi:10.1189/jlb.0506304 · Cited by 33
Self-citation
Distinct Roles of CSF-1 Isoforms in Lupus Nephritis
Weinmann‐Menke, J., Iwata, Y., Rabacal, W., Basu, R., Stanley, E. R., & Kelley, V. R. (2011) · Journal of the American Society of Nephrology · doi:10.1681/asn.2011010038 · Cited by 33
Self-citation
Early growth response 2 negatively modulates osteoclast differentiation through upregulation of Id helix–loop–helix proteins
Kim, H., Hong, J. M., Yoon, K., Kim, N., Cho, D., Choi, J., Lee, I. K., & Kim, S. (2012) · Bone · doi:10.1016/j.bone.2012.07.015 · Cited by 33
Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Interacts With Colony-Stimulating Factor 1 Receptor (CSF1R) but Is Not Necessary for CSF1/CSF1R-Mediated Microglial Survival
Cheng, B., Li, X., Dai, K., Duan, S., Rong, Z., Chen, Y., Lü, L., Liu, Z., Huang, X., Xu, H., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.633796 · Cited by 34
Tumor-Associated Macrophages/Microglia in Glioblastoma Oncolytic Virotherapy: A Double-Edged Sword
Blitz, S. E., Kappel, A. D., Gessler, F. A., Klinger, N. V., Arnaout, O. M., Lu, Y., Peruzzi, P., Smith, T. R., Chiocca, E. A., Friedman, G. K., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031808 · Cited by 32
Targeting colonic macrophages improves glycemic control in high-fat diet-induced obesity
Rohm, T. V., Keller, L., Bosch, A. J. T., AlAsfoor, S., Baumann, Z., Thomas, A., Wiedemann, S. J., Steiger, L., Dalmas, É., Wehner, J., et al. (2022) · Communications Biology · doi:10.1038/s42003-022-03305-z · Cited by 33
Direct inhibitory and indirect stimulatory effects of RAGE ligand S100 on sRANKL‐induced osteoclastogenesis
Yoshida, T., Flegler, A. J., Kozlov, A., & Stern, P. H. (2009) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22192 · Cited by 32
Signaling networks regulating leukocyte podosome dynamics and function
Dovas, A., & Cox, D. (2011) · Cellular Signalling · doi:10.1016/j.cellsig.2011.02.004 · Cited by 34
The selective M-CSF receptor tyrosine kinase inhibitor Ki20227 suppresses experimental autoimmune encephalomyelitis
Uemura, Y., Ohno, H., Ohzeki, Y., Takanashi, H., Murooka, H., Kubo, K., & Serizawa, I. (2008) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2008.01.015 · Cited by 32
Enlarging the Nosological Spectrum of Hereditary Diffuse Leukoencephalopathy with Axonal Spheroids ( HDLS )
Hoffmann, S., Murrell, J. R., Harms, L., Miller, K., Meisel, A., Brosch, T., Scheel, M., Ghetti, B. F., Goebel, H., & Stenzel, W. (2014) · Brain Pathology · doi:10.1111/bpa.12120 · Cited by 32
Interleukin-34 as a promising clinical biomarker and therapeutic target for inflammatory arthritis
Udomsinprasert, W., Jittikoon, J., & Honsawek, S. (2019) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2019.05.005 · Cited by 31
Structure-based optimization of a potent class of arylamide FMS inhibitors
Meegalla, S. K., Wall, M. J., Chen, J., Wilson, K. J., Ballentine, S. K., DesJarlais, R. L., Schubert, C., Crysler, C. S., Chen, Y., Molloy, C. J., et al. (2008) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2008.04.059 · Cited by 31
MicroRNA-Mediated Down-Regulation of M-CSF Receptor Contributes to Maturation of Mouse Monocyte-Derived Dendritic Cells
Riepsaame, J., van Oudenaren, A., den Broeder, B. J. H., van IJcken, W. F. J., Pothof, J., & Leenen, P. J. M. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00353 · Cited by 35
Integration of cytokine and transcription factor signals in hematopoietic stem cell commitment
Sarrazin, S., & Sieweke, M. H. (2011) · Seminars in Immunology · doi:10.1016/j.smim.2011.08.011 · Cited by 34
The Chemotactic Defect in Wiskott-Aldrich Syndrome Macrophages Is Due to the Reduced Persistence of Directional Protrusions
Ishihara, D., Dovas, A., Park, H., Isaac, B. M., & Cox, D. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030033 · Cited by 30
The impact of colony‐stimulating factor‐1 on fracture healing: An experimental study
Sarahrudi, K., Mousavi, M., Großschmidt, K., Sela, N., König, F., Vécsei, V., & Aharinejad, S. (2008) · Journal of Orthopaedic Research® · doi:10.1002/jor.20680 · Cited by 30
Lipocalin-2 inhibits osteoclast formation by suppressing the proliferation and differentiation of osteoclast lineage cells
Kim, H., Yoon, H., Yoon, K., Gwon, M., Seong, S. J., Suk, K., Kim, S., & Yoon, Y. (2015) · Experimental Cell Research · doi:10.1016/j.yexcr.2015.03.008 · Cited by 30
CSF-1 receptor-mediated differentiation of a new type of monocytic cell with B cell-stimulating activity: its selective dependence on IL-34
Yamane, F., Nishikawa, Y., Matsui, K., Asakura, M., Iwasaki, E., Watanabe, K., Tanimoto, H., Sano, H., Fujiwara, Y., Stanley, E. R., et al. (2013) · Journal of Leukocyte Biology · doi:10.1189/jlb.0613311 · Cited by 30
Self-citation
Identification of prognostic biomarkers for response to radiotherapy by DNA microarray in nasopharyngeal carcinoma patients
Chen, J. (2012) · International Journal of Oncology · doi:10.3892/ijo.2012.1341 · Cited by 30
Increased osteoclast formation and activity by peripheral blood mononuclear cells in chronic liver disease patients with osteopenia
Olivier, B. J., Schoenmaker, T., Mebius, R. E., Everts, V. E., Mulder, C. J. J., van Nieuwkerk, K. M. J., de Vries, T. J., & der Merwe, V. (2007) · Hepatology · doi:10.1002/hep.21971 · Cited by 29
Macrophage-Colony-Stimulating Factor-Induced Proliferation and Lipopolysaccharide-Dependent Activation of Macrophages Requires Raf-1 Phosphorylation to Induce Mitogen Kinase Phosphatase-1 Expression
Sànchez‐Tilló, E., Comalada, M., Farrera, C., Valledor, A. F., Lloberas, J., & Celada, A. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.11.6594 · Cited by 30
CSF1R+ myeloid-monocytic cells drive CAR-T cell resistance in aggressive B cell lymphoma
Stahl, D. J., Gödel, P., Balke‐Want, H., Gholamipoorfard, R., Segbers, P., Tetenborg, L., Koker, M., Dörr, J., Gregor, L., Bachurski, D., et al. (2025) · Cancer Cell · doi:10.1016/j.ccell.2025.05.013 · Cited by 37
Analysis of gene expression profile identifies potential biomarkers for atherosclerosis
Liu, L., Liu, Y., Liu, C., Zhang, Z., Du, Y., & Zhao, H. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.5650 · Cited by 29
Chronic pain and impaired glial glutamate transporter function in lupus‐prone mice are ameliorated by blocking macrophage colony‐stimulating factor‐1 receptors
Yan, X., Maixner, D. W., Li, F., & Weng, H. (2017) · Journal of Neurochemistry · doi:10.1111/jnc.13952 · Cited by 29
Macrophage differentiation of myeloid progenitor cells in response to M-CSF is regulated by the dual-specificity phosphatase DUSP5
Grasset, M.-F., Gobert, S., Mouchiroud, G., & Bourette, R. P. (2009) · Journal of Leukocyte Biology · doi:10.1189/jlb.0309151 · Cited by 28
Epstein-Barr Virus-Encoded BARF1 Protein is a Decoy Receptor for Macrophage Colony Stimulating Factor and Interferes with Macrophage Differentiation and Activation
Hoebe, E. K., Large, T. Y. S. L., Tarbouriech, N., Oosterhoff, D., de Gruijl, T. D., Middeldorp, J. M., & Greijer, A. E. (2012) · Viral Immunology · doi:10.1089/vim.2012.0034 · Cited by 29
Distinct In Vivo Roles of Colony-Stimulating Factor-1 Isoforms in Renal Inflammation
Jang, M.-H., Herber, D., Jiang, X., Nandi, S., Dai, X.-M., Zeller, G. C., Stanley, E. R., & Kelley, V. R. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.6.4055 · Cited by 29
Self-citation
Design and synthesis of a pyrido[2,3-d]pyrimidin-5-one class of anti-inflammatory FMS inhibitors
Huang, H., Hutta, D. A., Hu, H., DesJarlais, R. L., Schubert, C., Petrounia, I. P., Chaikin, M. A., Manthey, C. L., & Player, M. R. (2008) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2008.02.070 · Cited by 29
Modulating tumor-associated macrophages through CSF1R inhibition: a potential therapeutic strategy for HNSCC
Chen, K., Li, X., Dong, S., Guo, Y., Luo, Z., Zhuang, S., Liu, J., Liu, T., Liao, J., & Wen, W. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-024-06036-3 · Cited by 35
Principles of Immunophenotyping
Naeim, F. (2008) · Elsevier eBooks · doi:10.1016/b978-0-12-370607-2.00002-8 · Cited by 28
Research progress on immunotherapy in triple‑negative breast cancer (Review)
Zhang, X., Ge, X., Jiang, T., Yang, R., & Li, S. (2022) · International Journal of Oncology · doi:10.3892/ijo.2022.5385 · Cited by 28
SR-A ligand and M-CSF dynamically regulate SR-A expression and function in primary macrophages via p38 MAPK activation
Nikolic, D. M., Cormier, L. E., Du, L., & Post, S. R. (2011) · BMC Immunology · doi:10.1186/1471-2172-12-37 · Cited by 28
Functional significance of mononuclear phagocyte populations generated through adult hematopoiesis
Gutknecht, M. F., & Bouton, A. H. (2014) · Journal of Leukocyte Biology · doi:10.1189/jlb.1ri0414-195r · Cited by 30
Characterisation of the osteoclastogenic potential of human osteoblastic and fibroblastic conditioned media
Costa-Rodrigues, J., Teixeira, C., Sampaio, P., & Fernandes, M. H. (2009) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22398 · Cited by 31
Differentiation-dependent antiviral capacities of amphibian (Xenopus laevis) macrophages
Yaparla, A., Popović, M., & Grayfer, L. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.794065 · Cited by 28
Potent 2′-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents
Patch, R. J., Brandt, B. M., Asgari, D., Baindur, N., Chadha, N. K., Georgiadis, T. M., Cheung, W. S., Petrounia, I. P., Donatelli, R. R., Chaikin, M. A., et al. (2007) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2007.09.057 · Cited by 28
Selection and growth regulation of genetically modified cells with hapten‐specific antibody/receptor tyrosine kinase chimera
Tanaka, K., Kawahara, M., Ueda, H., & Nagamune, T. (2009) · Biotechnology Progress · doi:10.1002/btpr.185 · Cited by 27
Increased bone loss and amount of osteoclasts in kinin B1 receptor knockout mice
Gonçalves‐Zillo, T. O., Pugliese, L. S., Sales, V., Mori, M. A., Squaiella‐Baptistão, C. C., Longo‐Maugéri, I. M., Lopes, J. D., de Oliveira, S. M., Monteiro, A. C., & Pesquero, J. B. (2013) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.12097 · Cited by 28
Low-dose IL-34 has no effect on osteoclastogenesis but promotes osteogenesis of hBMSCs partly via activation of the PI3K/AKT and ERK signaling pathways
Xu, J., Fu, L., Bai, J., Zhong, H., Kuang, Z., Zhou, C., Hu, B., Ni, L., Li, Y., Chen, E., et al. (2021) · Stem Cell Research & Therapy · doi:10.1186/s13287-021-02263-3 · Cited by 27
Goldfish (Carassius auratus L.) as a model system to study the growth factors, receptors and transcription factors that govern myelopoiesis in fish
Katzenback, B. A., Katakura, F., & Belosevic, M. (2015) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2015.10.024 · Cited by 28
Targeting Stromal-cancer Cell Interactions with siRNAs
Aharinejad, S., Sioud, M., Lucas, T., & Abraham, D. (2008) · Methods in molecular biology · doi:10.1007/978-1-60327-547-7_12 · Cited by 28
Pilot study of the antifibrotic effects of the multikinase inhibitor pacritinib in a mouse model of liver fibrosis
Al‐Fayoumi, S., Hashiguchi, T., Shirakata, Y., Mascarenhas, J. O., & Singer, J. W. (2018) · Journal of Experimental Pharmacology · doi:10.2147/jep.s150729 · Cited by 27
Chapter 6 Cell and Molecular Biology of the Novel Protein Tyrosine‐Phosphatase‐Interacting Protein 51
Stenzinger, A., Schreiner, D., Reiners-Koch, P.-S., Hofer, H. W., & Wimmer, M. A. (2009) · International review of cytology · doi:10.1016/s1937-6448(09)75006-3 · Cited by 28
Levels of myeloid‐related proteins in saliva for screening and monitoring of periodontal disease
Lira‐Junior, R., Bissett, S. M., Preshaw, P. M., Taylor, J. J., & Boström, E. A. (2021) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.13534 · Cited by 26
Biomarkers for Childhood-Onset Systemic Lupus Erythematosus
Abulaban, K. M., & Brunner, H. I. (2014) · Current Rheumatology Reports · doi:10.1007/s11926-014-0471-2 · Cited by 26
Tumor necrosis factor-alpha-converting enzyme activities and tumor-associated macrophages in breast cancer
Rego, S. L., Helms, R. S., & Dréau, D. (2013) · Immunologic Research · doi:10.1007/s12026-013-8434-7 · Cited by 26

Authors: Pixley, F. J., & Stanley, E. R.
Affiliations: Albert Einstein College of Medicine (US)
Corresponding author: Stanley, E. Richard
ORCID: Pixley, Fiona J.
Stanley, E. Richard
Venue: Trends in Cell Biology
Publisher: Elsevier BV
Published: 2004-11
Volume: 14
Issue: 11
Pages: 628-638
ISSN: 0962-8924 (ISSN-L)
DOI: 10.1016/j.tcb.2004.09.016
OpenAlex: W2032410318
Cited by: 807
References: 98
Citations by year: 2026: 19 · 2025: 34 · 2024: 50 · 2023: 32 · 2022: 45 · 2021: 41 · 2020: 36 · 2019: 34 · 2018: 30 · 2017: 39 · 2016: 33 · 2015: 34 · 2014: 44 · 2013: 40 · 2012: 45
FWCI: 2.17
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
doi.org/10.15223/policy-017 (stm-asf)
doi.org/10.15223/policy-037 (stm-asf)
doi.org/10.15223/policy-012 (stm-asf)
doi.org/10.15223/policy-029 (stm-asf)
doi.org/10.15223/policy-004 (stm-asf)
Locations: Trends in Cell Biology (publishedVersion)
PubMed (publishedVersion)
UWA Profiles and Research Repository (UWA) (submittedVersion)
Funders: National Institutes of Health (KO8 CA097348, PO1 CA100324, RO1 CA 25604, RO1 CA32551)
Albert Einstein Cancer Center (P30 CA13330)
Topics: Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
Life Sciences › Immunology and Microbiology › Immunology › Cytokine Signaling Pathways and Interactions
Life Sciences › Immunology and Microbiology › Immunology › Phagocytosis and Immune Regulation
Keywords: colony-stimulating factor 1, CSF-1 receptor, tissue macrophages, osteoclasts, macrophage chemotaxis, macrophage activation, signaling pathways, innate immunity, pathogenesis
MeSH terms: Animals, Humans, Macrophage Activation, Macrophages, Phosphorylation, Signal Transduction, Macrophage Colony-Stimulating Factor, Receptor, Macrophage Colony-Stimulating Factor

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

CSF-1 regulation of the wandering macrophage: complexity in action

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks