CSF-1 regulation of the wandering macrophage: complexity in action

Rho GTPases in cell biology

Etienne-Manneville, S., & Hall, A. (2002) · Nature · doi:10.1038/nature01148 · Cited by 4,965

Rho and Rac Take Center Stage

Burridge, K., & Wennerberg, K. (2004) · Cell · doi:10.1016/s0092-8674(04)00003-0 · Cited by 1,831

Obesity-induced inflammatory changes in adipose tissue

Wellen, K. E., & Hotamisligil, G. S. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200320514 · Cited by 1,823

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

Yoshida, H., Hayashi, S.-I., Kunisada, T., Ogawa, M., Nishikawa, S., Okamura, H., Sudo, T., Shultz, L. D., & Nishikawa, S.-I. (1990) · Nature · doi:10.1038/345442a0 · Cited by 1,789

Genetic regulation of osteoclast development and function

Teitelbaum, S. L., & Ross, F. P. (2003) · Nature Reviews Genetics · doi:10.1038/nrg1122 · Cited by 1,720

Colony-Stimulating Factor 1 Promotes Progression of Mammary Tumors to Malignancy

Lin, E. Y., Nguyen, A. V., Russell, R. G., & Pollard, J. W. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.193.6.727 · Cited by 1,594

Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects

Dai, X.-M., Ryan, G. R., Hapel, A. J., Dominguez, M. G., Russell, R. G., Kapp, S., Sylvestre, V., & Stanley, E. R. (2002) · Blood · doi:10.1182/blood.v99.1.111 · Cited by 1,184

Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse.

Wiktor-Jedrzejczak, W., Bartocci, A., Ferrante, A. W., Ahmed-Ansari, A., Sell, K. W., Pollard, J. W., & Stanley, E. R. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.12.4828 · Cited by 1,031

Involvement of Granulocyte-Macrophage Colony-Stimulating Factor in Pulmonary Homeostasis

Dranoff, G., Crawford, A. D., Sadelain, M., Neugeboren, B. I., Rashid, A., Bronson, R. T., Dickersin, G. R., Bachurski, C. J., Mark, E. L., Whitsett, J. A., et al. (1994) · Science · doi:10.1126/science.8171324 · Cited by 877

Divergent Signals and Cytoskeletal Assemblies Regulate Self-Organizing Polarity in Neutrophils

Xu, J., Wang, F., Keymeulen, A. V., Herzmark, P., Straight, A. F., Kelly, K., Takuwa, Y., Sugimoto, N., Mitchison, T. J., & Bourne, H. R. (2003) · Cell · doi:10.1016/s0092-8674(03)00555-5 · Cited by 684

Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy

Tushinski, R. J., Oliver, I. T., Guilbert, L. J., Tynan, P. W., Warner, J. R., & Stanley, E. R. (1982) · Cell · doi:10.1016/0092-8674(82)90376-2 · Cited by 663

Interplay between Rac and Rho in the control of substrate contact dynamics

Rottner, K., Hall, A., & Small, J. V. (1999) · Current Biology · doi:10.1016/s0960-9822(99)80286-3 · Cited by 649

Cbl: many adaptations to regulate protein tyrosine kinases

Thien, C. B. F., & Langdon, W. Y. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35067100 · Cited by 628

Podosomes: adhesion hot-spots of invasive cells

Linder, S., & Aepfelbacher, M. (2003) · Trends in Cell Biology · doi:10.1016/s0962-8924(03)00128-4 · Cited by 615

WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell mov

Takenawa, T., & Miki, H. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.10.1801 · Cited by 604

Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse

Cecchini, M. G., Dominguez, M. G., Mocci, S., Wetterwald, A., Felix, R., Fleisch, H. A., Chisholm, O., Hofstetter, W., Pollard, J. W., & Stanley, E. R. (1994) · Development · doi:10.1242/dev.120.6.1357 · Cited by 557

Paxillin: a focal adhesion-associated adaptor protein

Schaller, M. D. (2001) · Oncogene · doi:10.1038/sj.onc.1204786 · Cited by 546

A Role for Cdc42 in Macrophage Chemotaxis

Allen, W. E., Zicha, D., Ridley, A. J., & Jones, G. E. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.141.5.1147 · Cited by 528

RhoA is required for monocyte tail retraction during transendothelial migration

Worthylake, R. A., Lemoine, S., Watson, J. M., & Burridge, K. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.200103048 · Cited by 501

RAFTK/Pyk2-mediated cellular signalling

Avraham, H. K., Park, S., Schinkmann, K. A., & Avraham, S. (2000) · Cellular Signalling · doi:10.1016/s0898-6568(99)00076-5 · Cited by 459

Vascular Endothelial Growth Factor Can Substitute for Macrophage Colony-Stimulating Factor in the Support of Osteoclastic Bone Resorption

Niida, S., Kaku, M., Amano, H., Yoshida, H., Kataoka, H., Nishikawa, S., Tanne, K., Maeda, N., Nishikawa, S., & Kodama, H. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.190.2.293 · Cited by 443

Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages

Allen, W. E., Jones, G. E., Pollard, J. W., & Ridley, A. J. (1997) · Journal of Cell Science · doi:10.1242/jcs.110.6.707 · Cited by 409

Iba1 Is an Actin-Cross-Linking Protein in Macrophages/Microglia

Sasaki, Y., Ohsawa, K., Kanazawa, H., Kohsaka, S., & Imai, Y. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5388 · Cited by 373

Cbl Associates with Pyk2 and Src to Regulate Src Kinase Activity, αvβ3 Integrin-Mediated Signaling, Cell Adhesion, and Osteoclast Motility

Sanjay, A., Houghton, A., Neff, L., DiDomenico, E., Bardelay, C., Antoine, E., Levy, J. B., Gailit, J. O., Bowtell, D. D. L., Horne, W. C., et al. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.152.1.181 · Cited by 371

The Adaptor Protein Paxillin Is Essential for Normal Development in the Mouse and Is a Critical Transducer of Fibronectin Signaling

Hagel, M., George, E. L., Kim, A., Tamimi, R. M., Opitz, S. L., Turner, C. E., Imamoto, A., & Thomas, S. Μ. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.3.901-915.2002 · Cited by 332

Osteopetrosis, a New Recessive Skeletal Mutation on Chromosome 12 of the Mouse

Marks, S. C., & LANE, P. W. (1976) · Journal of Heredity · doi:10.1093/oxfordjournals.jhered.a108657 · Cited by 304

Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration

Okigaki, M., Davis, C., Falasca, M., Harroch, S., Felsenfeld, D. P., Sheetz, M. P., & Schlessinger, J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1834348100 · Cited by 299

The Cbl protooncoprotein stimulates CSF‐1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation

Lee, P. S. W., Wang, Y., Dominguez, M. G., Yeung, Y., Murphy, M. A., Bowtell, D. D. L., & Stanley, E. R. (1999) · The EMBO Journal · doi:10.1093/emboj/18.13.3616 · Cited by 255

Heterozygous osteopetrotic (op) mutation reduces atherosclerosis in LDL receptor- deficient mice.

Rajavashisth, T. B., Qiao, J. H., Tripathi, S., Tripathi, J., Mishra, N. K., Hua, M., Wang, X. P., Loussararian, A. H., Clinton, S. K., Libby, P., et al. (1998) · Journal of Clinical Investigation · doi:10.1172/jci119891 · Cited by 245

Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages

Vanhaesebroeck, B., Jones, G. E., Allen, W. E., Zicha, D., Hooshmand-Rad, R., Sawyer, C., Wells, C. M., Waterfield, M. D., & Ridley, A. J. (1999) · Nature Cell Biology · doi:10.1038/9045 · Cited by 236

Induction of macrophage production and proliferation by a purified colony stimulating factor

Stanley, E. R., Chen, D. M., & Lin, H. (1978) · Nature · doi:10.1038/274168a0 · Cited by 235

Rescue of the colony-stimulating factor 1 (CSF-1)–nullizygous mouse (Csf1op/Csf1op) phenotype with a CSF-1 transgene and identification of sites of local CSF-1 synthesis

Ryan, G. R., Dai, X.-M., Dominguez, M. G., Tong, W., Chuan, F.-C., Chisholm, O., Russell, R. G., Pollard, J. W., & Stanley, E. R. (2001) · Blood · doi:10.1182/blood.v98.1.74 · Cited by 224

The colony‐stimulating factors and collagen‐induced arthritis: exacerbation of disease by M‐CSF and G‐CSF and requirement for endogenous M‐CSF

Campbell, I., Rich, M. J., Bischof, R., & Hamilton, J. (2000) · Journal of Leukocyte Biology · doi:10.1189/jlb.68.1.144 · Cited by 219

Cellular signaling in macrophage migration and chemotaxis

Jones, G. E. (2000) · Journal of Leukocyte Biology · doi:10.1189/jlb.68.5.593 · Cited by 214

The trophoblast is a component of the innate immune system during pregnancy

Guleria, I., & Pollard, J. W. (2000) · Nature Medicine · doi:10.1038/75074 · Cited by 210

CSF-1 signal transduction

Hamilton, J. A. (1997) · Journal of Leukocyte Biology · doi:10.1002/jlb.62.2.145 · Cited by 206

Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration

Wells, C. M., Walmsley, M. J., Ooi, S. K. T., Tybulewicz, V. L. J., & Ridley, A. J. (2004) · Journal of Cell Science · doi:10.1242/jcs.00997 · Cited by 186

Sequence Requirements for Binding of Src Family Tyrosine Kinases to Activated Growth Factor Receptors

Alonso, G., Koegl, M., Mazurenko, N. N., & Courtneidge, S. A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.17.9840 · Cited by 186

Direct observation and quantification of macrophage chemoattraction to the growth factor CSF-1

Webb, S., Pollard, J. W., & Jones, G. E. (1996) · Journal of Cell Science · doi:10.1242/jcs.109.4.793 · Cited by 180

Macrophage Colony-stimulating Factor Promotes Cell Survival through Akt/Protein Kinase B

Kelley, T. W., Graham, M. M., Doseff, A. I., Pomerantz, R. W., Lau, S. M., Ostrowski, M. C., Franke, T. F., & Marsh, C. B. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.37.26393 · Cited by 171

Functional Heterogeneity of Colony-Stimulating Factor-Induced Human Nonocyte-Derived Macrophages

Akagawa, K. S. (2002) · International Journal of Hematology · doi:10.1007/bf02982715 · Cited by 169

Lipopolysaccharide Induces Actin Reorganization and Tyrosine Phosphorylation of Pyk2 and Paxillin in Monocytes and Macrophages

Williams, L. M., & Ridley, A. J. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.4.2028 · Cited by 160

Colony-stimulating factor (CSF) radioimmunoassay: detection of a CSF subclass stimulating macrophage production.

Stanley, E. R. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.6.2969 · Cited by 156

Human recombinant granulocyte-macrophage colony-stimulating factor and interleukin 3 cause basophil histamine release.

Haak‐Frendscho, M., Arai, N., Arai, K., Baeza, M. L., Finn, A., & Kaplan, A. P. (1988) · Journal of Clinical Investigation · doi:10.1172/jci113567 · Cited by 155

Cyclin D1Governs Adhesion and Motility of Macrophages

Neumeister, P., Pixley, F. J., Xiong, Y., Xie, H., Wu, K., Ashton, A. W., Cammer, M., Chan, A. Y., Symons, M. H., Stanley, E. R., et al. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.02-07-0102 · Cited by 152

Impaired integrin-mediated signal transduction, altered cytoskeletal structure and reduced motility in Hck/Fgr deficient macrophages

Suen, P. W., Ilić, D., Caveggion, E., Berton, G., Damsky, C. H., & Lowell, C. A. (1999) · Journal of Cell Science · doi:10.1242/jcs.112.22.4067 · Cited by 150

BLIMP-1: trigger for differentiation of myeloid lineage

Chang, D., Angelin‐Duclos, C., & Calame, K. L. (2000) · Nature Immunology · doi:10.1038/77861 · Cited by 149

Macrophages: important accessory cells for reproductive function

Cohen, P. E., Nishimura, K., Zhu, L., & Pollard, J. W. (1999) · Journal of Leukocyte Biology · doi:10.1002/jlb.66.5.765 · Cited by 147

Cytokine reference : a compendium of cytokines and other mediators of host defence

Durum, S. K., Oppenheim, J. J., Feldmann, M., Hirano, T., Vilec, J., & Nicola, N. A. (2001) · Academic Press eBooks · Cited by 145

Incomplete restoration of colony-stimulating factor 1 (CSF-1) function in CSF-1–deficient Csf1op/Csf1op mice by transgenic expression of cell surface CSF-1

Dai, X.-M., Zong, X.-H., Sylvestre, V. T., & Stanley, E. R. (2003) · Blood · doi:10.1182/blood-2003-08-2739 · Cited by 144

Interleukin 1 plus interleukin 3 plus colony-stimulating factor 1 are essential for clonal proliferation of primitive myeloid bone marrow cells.

Bartelmez, S., Bradley, T. R., Bertoncello, I., Mochizuki, D. Y., Tushinski, R. J., Stanley, E. R., Hapel, A. J., Young, I., Kriegler, A. B., & HODGSON, G. S. (1989) · PubMed · Cited by 128

Early Events in M-CSF Receptor Signaling

Bourette, R. P., & Rohrschneider, L. R. (2000) · Growth Factors · doi:10.3109/08977190009001065 · Cited by 125

Cytokine regulation of the macrophage (M phi) system studied using the colony stimulating factor-1-deficient op/op mouse

Wiktor-Jedrzejczak, W., & Gordon, S. (1996) · Physiological Reviews · doi:10.1152/physrev.1996.76.4.927 · Cited by 125

Colony-stimulating factor-1 antisense treatment suppresses growth of human tumor xenografts in mice.

Aharinejad, S., Abraham, D., Paulus, P., ABRI, H., Hofmann, M., Großschmidt, K., Schäfer, R., Stanley, E. R., & Hofbauer, R. (2002) · PubMed · Cited by 121

Tyrosine phosphorylation of paxillin alpha is involved in temporospatial regulation of paxillin-containing focal adhesion formation and F-actin organization in motile cells.

Nakamura, K., Yano, H., Uchida, H., Hashimoto, S., SCHAEFER, E. M., & Sabe, H. (2000) · PubMed · doi:10.1074/jbc.m000679200 · Cited by 120

Rho proteins, PI 3‐kinases, and monocyte/macrophage motility

Ridley, A. J. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)02481-4 · Cited by 119

WASp deficiency in mice results in failure to form osteoclast sealing zones and defects in bone resorption

Calle, Y., Jones, G. E., Jagger, C. J., Fuller, K., Blundell, M. P., Chow, J. W. M., Chambers, T. J., & Thrasher, A. J. (2004) · Blood · doi:10.1182/blood-2003-04-1259 · Cited by 117

The Inositol 5′-Phosphatase SHIP-1 and the Src Kinase Lyn Negatively Regulate Macrophage Colony-stimulating Factor-induced Akt Activity

Baran, C. P., Tridandapani, S., Helgason, C. D., Humphries, R. K., Krystal, G., & Marsh, C. B. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305021200 · Cited by 106

Pleiotropic Roles for CSF-1 in Development Defined by the Mouse Mutation Osteopetrotic

Pollard, J. W., & Stanley, E. R. (1996) · Advances in developmental biochemistry · doi:10.1016/s1064-2722(08)60060-2 · Cited by 105

Both Src-Dependent and -Independent Mechanisms Mediate Phosphatidylinositol 3-Kinase Regulation of Colony-Stimulating Factor 1-Activated Mitogen-Activated Protein Kinases in Myeloid Progenitors

Lee, A. W. ‐., & States, D. J. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.18.6779-6798.2000 · Cited by 103

Reduced Macrophage Recruitment, Proliferation, and Activation in Colony-Stimulating Factor-1-Deficient Mice Results in Decreased Tubular Apoptosis During Renal Inflammation

Lenda, D. M., Kikawada, E., Stanley, E. R., & Kelley, V. R. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.170.6.3254 · Cited by 101

Tyrosine Phosphorylation of Paxillin α Is Involved in Temporospatial Regulation of Paxillin-containing Focal Adhesion Formation and F-actin Organization in Motile Cells

Nakamura, K., Yano, H., Uchida, H., Hashimoto, S., SCHAEFER, E. M., & Sabe, H. (2000) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)61492-4 · Cited by 101

Phagocytic signaling strategies: Fcγreceptor-mediated phagocytosis as a model system

Cox, D., & Greenberg, S. (2001) · Seminars in Immunology · doi:10.1006/smim.2001.0330 · Cited by 98

Scaffolding Protein Gab2 Mediates Differentiation Signaling Downstream of Fms Receptor Tyrosine Kinase

Liu, Y., Jenkins, B. J., Shin, J. L., & Rohrschneider, L. R. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.9.3047-3056.2001 · Cited by 96

Alveolar macrophage deficiency in osteopetrotic mice deficient in macrophage colony-stimulating factor is spontaneously corrected with age and associated with matrix metalloproteinase expression and emphysema

Shibata, Y., Zsengellér, Z. K., Otake, K., Palaniyar, N., & Trapnell, B. C. (2001) · Blood · doi:10.1182/blood.v98.9.2845 · Cited by 85

C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus

Wilhelmsen, K., Burkhalter, S., & van der Geer, P. (2002) · Oncogene · doi:10.1038/sj.onc.1205166 · Cited by 76

Proteomic Approaches to the Analysis of Early Events in Colony-stimulating Factor-1 Signal Transduction

Yeung, Y.-G., & Stanley, E. R. (2003) · Molecular & Cellular Proteomics · doi:10.1074/mcp.r300009-mcp200 · Cited by 74

Colony-stimulating factor-1 induces rapid behavioural responses in the mouse macrophage cell line, BAC1.2F5

Boocock, C. A., Jones, G. E., Stanley, E. R., & Pollard, J. W. (1989) · Journal of Cell Science · doi:10.1242/jcs.93.3.447 · Cited by 74

Protein Tyrosine Phosphatase φ Regulates Paxillin Tyrosine Phosphorylation and Mediates Colony-Stimulating Factor 1-Induced Morphological Changes in Macrophages

Pixley, F. J., Lee, P. S. W., Condeelis, J. S., & Stanley, E. R. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.5.1795-1809.2001 · Cited by 73

The expanding role of PI3-kinase in bone

Golden, L., & Insogna, K. L. (2003) · Bone · doi:10.1016/j.bone.2003.09.005 · Cited by 71

Macrophage-Colony-Stimulating Factor-Induced Activation of Extracellular-Regulated Kinase Involves Phosphatidylinositol 3-Kinase and Reactive Oxygen Species in Human Monocytes

Bhatt, N. Y., Kelley, T. W., Khramtsov, V. V., Wang, Y., Lam, G. K., Clanton, T. L., & Marsh, C. B. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.11.6427 · Cited by 70

Complexity in Uterine Macrophage Responses to Cytokines in Mice1

Pollard, J. W., Lin, E. Y., & Zhu, L. (1998) · Biology of Reproduction · doi:10.1095/biolreprod58.6.1469 · Cited by 64

Marginal Zone Macrophages and Immune Responses Against Viruses

Oehen, S., Odermatt, B., Karrer, U. W., Hengartner, H., Zinkernagel, R. M., & López-Macías, C. I. R. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.3.1453 · Cited by 56

The Related Adhesion Focal Tyrosine Kinase (RAFTK) Is Tyrosine Phosphorylated and Participates in Colony-Stimulating Factor-1/Macrophage Colony-Stimulating Factor Signaling in Monocyte-Macrophages

Hatch, W. C., Ganju, R. K., Hiregowdara, D., Avraham, S., & Groopman, J. E. (1998) · Blood · doi:10.1182/blood.v91.10.3967 · Cited by 55

Autoinhibitory mechanisms in receptor tyrosine kinases

Hubbard, S. R. (2002) · Frontiers in bioscience · doi:10.2741/a778 · Cited by 51

Tyrosine phosphorylation of a common 57-kDa protein in growth factor-stimulated and -transformed cells.

Li, W., Yeung, Y. G., & Stanley, E. R. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)89572-6 · Cited by 51

A Novel Macrophage Actin-associated Protein (MAYP) Is Tyrosine-phosphorylated following Colony Stimulating Factor-1 Stimulation

Yeung, Y.-G., Soldera, S., & Stanley, E. R. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.46.30638 · Cited by 49

FMIP, a novel Fms-interacting protein, affects granulocyte/macrophage differentiation

Tamura, T., Mancini, A., Joos, H., Koch, A., Hakim, C., Dumanski, J. P., Weidner, K. M., & Niemann, H. (1999) · Oncogene · doi:10.1038/sj.onc.1203062 · Cited by 48

Cutting Edge: A Possible Role for CD4+ Thymic Macrophages as Professional Scavengers of Apoptotic Thymocytes

Esashi, E., Sekiguchi, T., Ito, H., Koyasu, S., & Miyajima, A. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.6.2773 · Cited by 46

Suppressor of Cytokine Signaling 1 Interacts with the Macrophage Colony-stimulating Factor Receptor and Negatively Regulates Its Proliferation Signal

Bourette, R. P., Sepulveda, P. D., Arnaud, S., Dubreuil, P. C., Rottapel, R. K., & Mouchiroud, G. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101878200 · Cited by 45

The N Termini of Focal Adhesion Kinase Family Members Regulate Substrate Phosphorylation, Localization, and Cell Morphology

Dunty, J., & Schaller, M. D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m201779200 · Cited by 45

Expression and tyrosine phosphorylation of Cbl regulates macrophage chemokinetic and chemotactic movement

Caveggion, E., Continolo, S., Pixley, F. J., Stanley, E. R., Bowtell, D. D. L., Lowell, C. A., & Berton, G. (2003) · Journal of Cellular Physiology · doi:10.1002/jcp.10236 · Cited by 44

Tyrosines 559 and 807 in the cytoplasmic tail of the macrophage colony-stimulating factor receptor play distinct roles in osteoclast differentiation and function.

Feng, X., Takeshita, S., Namba, N., Wei, S., Teitelbaum, S., & Ross, F. (2002) · Endocrinology · doi:10.1210/en.2002-220467 · Cited by 43

M-CSF induced differentiation of myeloid precursor cells involves activation of PKC-δ and expression of Pkare

Junttila, I., Bourette, R. P., Rohrschneider, L. R., & Silvennoinen, O. (2003) · Journal of Leukocyte Biology · doi:10.1189/jlb.0702359 · Cited by 43

The relationship between different high proliferative potential colony-forming cells in mouse bone marrow.

Kriegler, A., Sm, V., Bernardo, D., & Bertoncello, I. (1994) · PubMed · Cited by 43

The major SHP-1-binding, tyrosine-phosphorylated protein in macrophages is a member of the KIR/LIR family and an SHP-1 substrate

Berg, K. L., Carlberg, K., Rohrschneider, L. R., Siminovitch, K. A., & Stanley, E. R. (1998) · Oncogene · doi:10.1038/sj.onc.1202203 · Cited by 40

Induced Expression and Association of the Mona/Gads Adapter and Gab3 Scaffolding Protein during Monocyte/Macrophage Differentiation

Bourgin, C., Bourette, R. P., Arnaud, S., Liu, Y., Rohrschneider, L. R., & Mouchiroud, G. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.11.3744-3756.2002 · Cited by 36

Increased Circulating Colony-Stimulating Factor-1 (CSF-1) in SJL/J Mice With Radiation-Induced Acute Myeloid Leukemia (AML) Is Associated With Autocrine Regulation of AML Cells by CSF-1

Haran‐Ghera, N., Krautghamer, R., Lapidot, T., Peled, A., Dominguez, M. G., & Stanley, E. R. (1997) · Blood · doi:10.1182/blood.v89.7.2537 · Cited by 26

Colony-Stimulating Factor 1-Dependent Cells Protect against Systemic Infection with Listeria monocytogenes but Facilitate Neuroinvasion

Jin, Y., Dons, L. E., Kristensson, K., & Rottenberg, M. E. (2002) · Infection and Immunity · doi:10.1128/iai.70.8.4682-4686.2002 · Cited by 23

Colony-stimulating factor-1 (CSF-1) receptor-mediated macrophage differentiation in myeloid cells: a role for tyrosine 559-dependent protein phosphatase 2A (PP2A) activity

McMahon, K., Wilson, N. J., Marks, D. C., Beecroft, T., Whitty, G. A., Hamilton, J. A., & Csar, X. F. (2001) · Biochemical Journal · doi:10.1042/0264-6021:3580431 · Cited by 22

Lineage-dependent NF-κB activation contributes to the resistance of human macrophages to apoptosis

Zhang, J., Li, Y., Yu, M., Chen, B., & Shen, B. (2003) · The Hematology Journal · doi:10.1038/sj.thj.6200252 · Cited by 21

Mechanism of phosphatidylinositol 3-kinase-dependent increases in BAC1.2F5 macrophage-like cell density in response to M-CSF: Phosphatidylinositol 3-kinase inhibitors increase the rate of apoptosis rather than inhibit DNA synthesis

Murray, J. T., Craggs, G., Wilson, L., & Kellie, S. (2000) · Inflammation Research · doi:10.1007/s000110050638 · Cited by 19

A novel 110 kDa form of myosin XVIIIA (MysPDZ) is tyrosine-phosphorylated after colony-stimulating factor-1 receptor signalling

Cross, M., Csar, X. F., Wilson, N. J., Manès, G., Addona, T. A., Marks, D. C., Whitty, G. A., Ashman, K., & Hamilton, J. A. (2004) · Biochemical Journal · doi:10.1042/bj20031978 · Cited by 19

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Kaku, M., Tsutsui, K., Motokawa, M., Kawata, T., Fujita, T., Kohno, S., Tohma, Y., Ohtani, J., Tenjoh, K., & Tanne, K. (2003) · Brain Research Protocols · doi:10.1016/j.brainresprot.2003.09.001 · Cited by 18

Independently arising macrophage mutants dissociate growth factor-regulated survival and proliferation.

Pollard, J. W., Morgan, C. J., Sbarba, P. D., Cheers, C., & Stanley, E. R. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.4.1474 · Cited by 13

Untitled work

(1997) · doi:10.1002/(sici)1098-2795(199701)46:1

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Colony-stimulating factors in inflammation and autoimmunity

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CSF-1 as a regulator of macrophage activation and immune responses.

Sweet, M. J., & Hume, D. A. (2003) · PubMed · Cited by 108

Macrophage Migration and Its Regulation by CSF-1

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CSF-1 receptor signaling in myeloid cells.

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