NAD+ and sirtuins in aging and disease

Imai, Shin-ichiro, Guarente, Leonard·2014·Trends in Cell Biology

Cited by (1,000)

Items 501–600 of 1,000

  1. Healthy Lifestyle Recommendations: Do the Beneficial Effects Originate from NAD+ Amount at the Cellular Level?
    Borut Poljšak, Vito Kovač, Irina Milisav · 2020 · Oxidative Medicine and Cellular Longevity
  2. Comparative metabolomic analysis in plasma and cerebrospinal fluid of humans and in plasma and brain of mice following antidepressant-dose ketamine administration
    Ruin Moaddel, Panos Zanos, Cristan Farmer, Bashkim Kadriu, Patrick J. Morris, Jacqueline Lovett, Elia E. Acevedo-Diaz, Grace W. Cavanaugh, Peixiong Yuan, Mani Yavi et al. · 2022 · Translational Psychiatry
  3. TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity
    Harshad S. Ugamraj, Kevin H. Dang, Laure‐Hélène Ouisse, Benjamin Buelow, Eduardo N. Chini, Giulia Castello, James Allison, Starlynn Clarke, Laura M. Davison, Roland Buelow et al. · 2022 · mAbs
  4. Oxidative stress impairs the Nur77‐Sirt1 axis resulting in a decline in organism homeostasis during aging
    Yang Yu, Xiaoyu Song, Guojing Ma, Lixia Zheng, Xiaoxun Wang, Feng Chen, Tingting Liu, Huanlian Tian, Yingxi Xu, Danni Li et al. · 2023 · Aging Cell
  5. Visualization of Nicotine Adenine Dinucleotide Redox Homeostasis with Genetically Encoded Fluorescent Sensors
    Yuzheng Zhao, Zhuo Zhang, Yejun Zou, Yi An Yang · 2017 · Antioxidants and Redox Signaling
  6. Can adipokine visfatin be a novel marker of pregnancy‐related disorders in women with obesity?
    Anna Wnuk, Aleksandra Stangret, Mateusz Wątroba, Anna Edyta Platek, Marta Skoda, Krzysztof Cendrowski, Włodzimierz Sawicki, Dariusz Szukiewicz · 2020 · Obesity Reviews
  7. Neuroprotection of NAD+ and NBP against ischemia/reperfusion brain injury is associated with restoration of sirtuin-regulated metabolic homeostasis
    Xinxin Wang, Guang-Hui Mao, Qiqi Li, Jie Tang, Hua Zhang, Kang-Lin Wang, Lei Wang, Hong Ni, Rui Sheng, Zheng‐Hong Qin · 2023 · Frontiers in Pharmacology
  8. The immunometabolic reprogramming of microglia in Alzheimerʼs disease
    Hongli Chen, Zichen Guo, Yaxuan Sun, Xueling Dai · 2023 · Neurochemistry International
  9. Application of omics in the diagnosis, prognosis, and treatment of acute myeloid leukemia
    Zhiyu Zhang, Jiayi Huang, Zhibo Zhang, Hongjie Shen, Xiaowen Tang, Depei Wu, Xiebing Bao, Guoqiang Xu, Suning Chen · 2024 · Biomarker Research
  10. Molecular and Cellular Mechanisms of Immunosenescence: Modulation Through Interventions and Lifestyle Changes
    Luca Pangrazzi, Andreas Meryk · 2024 · Biology
  11. Epigenetics and nutrition-related epidemics of metabolic diseases: Current perspectives and challenges
    Anna Hernández‐Aguilera, Salvador Fernández‐Arroyo, Elisabet Cuyàs, Fedra Luciano‐Mateo, Noemí Cabré, Jordi Camps, José López‐Miranda, Javier Abel Menéndez, Jorge Joven · 2016 · Food and Chemical Toxicology
  12. Silencing forkhead box M1 promotes apoptosis and autophagy through SIRT7/mTOR/IGF2 pathway in gastric cancer cells
    Wei Yu, Xiaofeng Cui, Zhongyi Wan, Yanhui Yu, Xiumin Liu, Lifang Jin · 2018 · Journal of Cellular Biochemistry
  13. Targeting anti‐aging protein sirtuin (Sirt) in the diagnosis of idiopathic pulmonary fibrosis
    Sadiya Bi Shaikh, Ashwini Prabhu, Yashodhar P. Bhandary · 2018 · Journal of Cellular Biochemistry
  14. Therapeutic potential of nicotinamide adenine dinucleotide (NAD)
    Marta Arenas‐Jal, Josep Maria Suñé-Negre, Encarna García‐Montoya · 2020 · European Journal of Pharmacology
  15. Metabolic syndrome exacerbates amyloid pathology in a comorbid Alzheimer's mouse model
    Alpna Tyagi, Carol Mirita, Nadine Taher, Iman Shah, Emily Moeller, Anit Tyagi, Thomas Chong, Subbiah Pugazhenthi · 2020 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  16. Mitochondrial dysregulation occurs early in ALS motor cortex with TDP-43 pathology and suggests maintaining NAD+ balance as a therapeutic strategy
    Mukesh Gautam, Aksu Günay, Navdeep S. Chandel, P. Hande Özdinler · 2022 · Scientific Reports
  17. Redox Homeostasis in Cardiovascular Disease: The Role of Mitochondrial Sirtuins
    Alberto Zullo, Rosa Guida, Rosaria Sciarrillo, Francesco Paolo Mancini · 2022 · Frontiers in Endocrinology
  18. Combination of resolvin E1 and lipoxin A4 promotes the resolution of pulpitis by inhibiting NF‐κB activation through upregulating sirtuin 7 in dental pulp fibroblasts
    Xiaochen Liu, Chunmeng Wang, Liping Pang, Liangliang Pan, Qi Zhang · 2022 · Cell Proliferation
  19. Mechanism of Allosteric Modulation of Nicotinamide Phosphoribosyltransferase to Elevate Cellular NAD+
    Kiira M Ratia, Zhengnan Shen, Jesse M. Gordon-Blake, Hyun Lee, Megan S. Laham, Isabella S. Krider, Nicholas Christie, Martha S Ackerman-Berrier, Christopher Penton, Natalie G. Knowles et al. · 2023 · Biochemistry
  20. Alterations of SIRT1 / SIRT3 subcellular distribution in aging undermine cardiometabolic homeostasis during ischemia and reperfusion
    Jingwen Zhang, Hao Wang, Lily A. Slotabec, Feng Cheng, Yi Tan, Ji Li · 2023 · Aging Cell
  21. The circadian clock in adult neural stem cell maintenance
    Swip Draijer, Inês Chaves, Marco F.M. Hoekman · 2018 · Progress in Neurobiology
  22. Effects of Chronic NAD Supplementation on Energy Metabolism and Diurnal Rhythm in Obese Mice
    Eun Roh, Gil Myoung Kang, So Young Gil, Chan Hee Lee, Seongjun Kim, Hong Dugu, Gi Hoon Son, Min‐Seon Kim · 2018 · Obesity
  23. Longevity-Promoting Pathways and Transcription Factors Respond to and Control Extracellular Matrix Dynamics During Aging and Disease
    Tinka Vidović, Collin Y. Ewald · 2022 · Frontiers in Aging
  24. Taurine, homotaurine, GABA and hydrophobic amino acids content influences “in vitro” antioxidant and SIRT1 modulation activities of enzymatic protein hydrolysates from algae
    Carlos Terriente-Palacios, Susana Rubiño, María Hortos, César Peteiro, Massimo Castellari · 2022 · Scientific Reports
  25. The impact of aging on liver health and the development of liver diseases
    Sha Neisha Williams, Wen‐Xing Ding · 2025 · Hepatology Communications
  26. The NAD + precursor nicotinic acid improves genomic integrity in human peripheral blood mononuclear cells after X-irradiation
    Kathrin Weidele, Sascha Beneke, Alexander Bürkle · 2017 · DNA repair
  27. Mitochondrial Metabolism and Aging in Yeast
    Giacomo Baccolo, Giulia Stamerra, Damiano Pellegrino-Coppola, Ivan Orlandi, Marina Vai · 2018 · International review of cytology
  28. Aging Kidney and Aging-Related Disease
    Zhongchi Li, Zhao Wang · 2018 · Advances in experimental medicine and biology
  29. Acute sources of mitochondrial NAD+ during respiratory chain dysfunction
    Christos Chinopoulos · 2020 · Experimental Neurology
  30. Hypothalamic NAD+-Sirtuin Axis: Function and Regulation
    Eun Roh, Min‐Seon Kim · 2020 · Biomolecules
  31. Aging and leukemic evolution of hematopoietic stem cells under various stress conditions
    Shuhei Kurosawa, Atsushi Iwama · 2020 · Inflammation and Regeneration
  32. Nicotinamide Supplementation Attenuates Renal Interstitial Fibrosis via Boosting the Activity of Sirtuins
    Xin Zhen, Shao-Wu Zhang, Feifei Xie, Miaomiao Zhou, Zheng Hu, Fengxin Zhu, Jing Nie · 2021 · Kidney Diseases
  33. Mitochondrial sirtuins in stem cells and cancer
    Amit Jaiswal, Zhu Xudong, Zhenyu Ju, Gabriele Christine Saretzki · 2021 · FEBS Journal
  34. NAD+-boosting molecules suppress mast cell degranulation and anaphylactic responses in mice
    Hyun-Woo Kim, Ga-Hee Ryoo, Hyun‐Young Jang, So‐Young Rah, Dong Hyun Lee, Do‐Kyun Kim, Eun Ju Bae, Byung‐Hyun Park · 2022 · Theranostics
  35. Targeting Mitochondrial Sirtuins in Age-Related Neurodegenerative Diseases and Fibrosis
    Haoxiang Xiao, Yuqiao Xie, Kaiwen Xi, Jinyi Xie, Mingyue Liu, Yangming Zhang, Zishuo Cheng, Wenting Wang, Baolin Guo, Shengxi Wu · 2023 · Aging and Disease
  36. Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity
    Cristiana O’Brien, Tianyi Ling, Jacob M. Berman, Rachel Culp‐Hill, Julie A. Reisz, Vincent Rondeau, Soheil Jahangiri, Jonathan R. St‐Germain, Vinitha Macwan, Audrey Astori et al. · 2023 · Haematologica
  37. A Review of Telomere Attrition in Cancer and Aging: Current Molecular Insights and Future Therapeutic Approaches
    Mina Iskandar, Miguel Xiao Barbero, Mohammed Tariq Jaber, Roy Chen, Romulo Gomez-Guevara, Edwin Cruz, Sandy D. Westerheide · 2025 · Cancers
  38. NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging
    Sabina Chubanava, Iuliia E. Karavaeva, Amy M. Ehrlich, Roger M. Justicia, Astrid Linde Basse, Ivan Kulik, Emilie Dalbram, Danial Ahwazi, Samuel R. Heaselgrave, Kajetan Trôst et al. · 2025 · Cell Metabolism
  39. Epigenetic regulation of histone modifications in glioblastoma: recent advances and therapeutic insights
    Li Zhang, Yang Yang, Yanchu Li, Chenyu Wang, Chenbin Bian, Hongbin Wang, Feng Wang · 2025 · Biomarker Research
  40. Associations among Metabolism, Circadian Rhythm and Age-Associated Diseases
    Yiwei Cao, Rui-Hong Wang · 2017 · Aging and Disease
  41. Nicotinamide N -Methyltransferase in Health and Cancer
    David Boyer Ramsden, Rosemary H. Waring, David J. Barlow, Richard B. Parsons · 2017 · International Journal of Tryptophan Research
  42. Two Different Methods of Quantification of Oxidized Nicotinamide Adenine Dinucleotide (NAD+) and Reduced Nicotinamide Adenine Dinucleotide (NADH) Intracellular Levels: Enzymatic Coupled Cycling Assay and Ultra-performance Liquid Chromatography (UPLC)-Mass Spectrometry
    Karina S. Kanamori, Guilherme C. de Oliveira, Maria Auxiliadora‐Martins, Renee A. Schoon, Joel M. Reid, Eduardo N. Chini · 2018 · BIO-PROTOCOL
  43. Cysteine thiol oxidation on SIRT2 regulates inflammation in obese mice with sepsis
    Xianfeng Wang, Nancy L. Buechler, David L. Long, Cristina M. Furdui, Barbara K. Yoza, Charles E. McCall, Vidula Vachharajani · 2018 · Inflammation
  44. Discovery of Selective SIRT2 Inhibitors as Therapeutic Agents in B-Cell Lymphoma and Other Malignancies
    Sarwat Chowdhury, Smitha P. Sripathy, Alyssa A. Webster, Angela Park, Uyen Lao, Joanne H. Hsu, Taylor K. Loe, Antonio Bedalov, Julian A. Simon · 2020 · Molecules
  45. The mitohormetic response as part of the cytoprotection mechanism of berberine
    Xiaofei Zhu, Yihui Wei, Beibei Yang, Xiaoxiao Yin, Xiaofang Guo · 2020 · Molecular Medicine
  46. Sirtuin activation targets IDH-mutant tumors
    Julie J. Miller, Alexandria L. Fink, Jack A Banagis, Hiroaki Nagashima, Megha P. Subramanian, Christine Kyuyoung Lee, Lisa Melamed, Shilpa S. Tummala, Kensuke Tateishi, Hiroaki Wakimoto et al. · 2020 · Neuro-Oncology
  47. Vitamins and Uterine Fibroids: Current Data on Pathophysiology and Possible Clinical Relevance
    Michał Ciebiera, Mohamed K. Ali, Magdalena Zgliczyńska, Maciej Skrzypczak, Ayman A. Al-Hendy · 2020 · International Journal of Molecular Sciences
  48. Mitochondrion-driven nephroprotective mechanisms of novel glucose lowering medications
    Barış Afşar, Mads Hornum, Rengin Elsürer Afşar, Lale A. Ertuğlu, Alberto Ortíz, Adrian Constantin Covic, Daniël H. van Raalte, David Z.I. Cherney, Mehmet Kanbay · 2021 · Mitochondrion
  49. The Interplay Between Autophagy and Senescence in Anthracycline Cardiotoxicity
    Michele Russo, Enrico Bono, Alessandra Ghigo · 2021 · Current Heart Failure Reports
  50. HMGB1 is a critical molecule in the pathogenesis of Gram-negative sepsis
    Jan Andersson, Huan Yang · 2022 · Journal of Intensive Medicine
  51. Pterostilbene in Combination With Mitochondrial Cofactors Improve Mitochondrial Function in Cellular Models of Mitochondrial Diseases
    Juan Miguel Suarez-Rivero, Carmen J. Pastor‐Maldonado, Ana Romero-González, David Gómez-Fernández, Suleva Povea-Cabello, Mónica Álvarez-Córdoba, Irene Villalón-García, Marta Talaverón-Rey, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza et al. · 2022 · Frontiers in Pharmacology
  52. Enhancement of Replication and Differentiation Potential of Human Bone Marrow Stem Cells by Nicotinamide Treatment
    J. Ok, Seon Beom Song, Eun Seong Hwang · 2018 · International Journal of Stem Cells
  53. CD38 Causes Autophagic Flux Inhibition and Cardiac Dysfunction Through a Transcriptional Inhibition Pathway Under Hypoxia/Ischemia Conditions
    Xingyue Zhang, Lingfei Li, Qiong Zhang, Qinglin Wei, Jiezhi Lin, Jiezhi Jia, Junhui Zhang, Tiantian Yan, Yanling Lv, Xupin Jiang et al. · 2020 · Frontiers in Cell and Developmental Biology
  54. Insights into the Conserved Regulatory Mechanisms of Human and Yeast Aging
    Rashmi Dahiya, Taj Mohammad, Mohamed Fahad Alajmi, Md Tabish Rehman, Gulam Mustafa Hasan, Afzal Hussain, Md. Imtaiyaz Hassan · 2020 · Biomolecules
  55. Senescence‐Targeted and NAD + ‐Dependent SIRT1‐Activated Nanoplatform to Counteract Stem Cell Senescence for Promoting Aged Bone Regeneration
    Ying Wang, Fangru Xie, Zirui He, Lingbin Che, Xi Chen, Yuan Yuan, Changsheng Liu · 2023 · Small
  56. Channeling Nicotinamide Phosphoribosyltransferase (NAMPT) to Address Life and Death
    Velma Ganga Reddy, Isabella S. Krider, Erick T. M. Alves, Jenna M. Courey, Megan S. Laham, Gregory R. J. Thatcher · 2024 · Journal of Medicinal Chemistry
  57. Advancements in NMN biotherapy and research updates in the field of digestive system diseases
    Guanyi Liao, Yuchen Xie, Hong Peng, Tianke Li, Xinsen Zou, Faguo Yue, Jinjun Guo, Li Rong · 2024 · Journal of Translational Medicine
  58. Physiologic Mechanical Stress Directly Induces Bone Formation by Activating Glucose Transporter 1 (Glut 1) in Osteoblasts, Inducing Signaling via NAD+-Dependent Deacetylase (Sirtuin 1) and Runt-Related Transcription Factor 2 (Runx2)
    Shu Somemura, Takanori Kumai, Kanaka Yatabe, Chizuko Sasaki, Hiroto Fujiya, Hisateru Niki, Kazuo Yudoh · 2021 · International Journal of Molecular Sciences
  59. NAD+ Metabolism and Diseases with Motor Dysfunction
    Samuel Lundt, Shinghua Ding · 2021 · Genes
  60. Nicotinamide mononucleotide supplementation improves the quality of porcine oocytes under heat stress
    Meijie Song, Yu Li, Yihang Zhou, Jiner Yan, Xiaohua Zhou, Qian Gao, Yilong Miao, Bo Xiong · 2022 · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
  61. Exosomes from senescent epithelial cells activate pulmonary fibroblasts via the miR-217-5p/Sirt1 axis in paraquat-induced pulmonary fibrosis
    Min Zhang, Xiang Xue, Zhenshuai Lou, Yanhong Lin, Qian Li, Changbao Huang · 2024 · Journal of Translational Medicine
  62. Replicative Senescence in Human Fibroblasts Is Delayed by Hydrogen Sulfide in a NAMPT/SIRT1 Dependent Manner
    Reiko Sanokawa‐Akakura, Shin Akakura, SIAMAK S. TABIBZADEH · 2016 · PLoS ONE
  63. Aging: A cell source limiting factor in tissue engineering
    Mohammadhossein Khorraminejad‐Shirazi, Mohammadreza Dorvash, AliReza Estedlal, Amir Human Hoveidaei, Mohsen Mazloomrezaei, Pouria Mosaddeghi · 2019 · World Journal of Stem Cells
  64. Inhibition of Knee Osteoarthritis Progression in Mice by Administering SRT2014, an Activator of Silent Information Regulator 2 Ortholog 1
    Nobuaki Miyaji, Kyohei K. Nishida, Toshikazu Tanaka, Daisuke Araki, Noriyuki Kanzaki, Yuichi Y. Hoshino, Ryosuke Kuroda, Takehiko Matsushita · 2020 · Cartilage
  65. Mitochondrial quality control: the real dawn of intervertebral disc degeneration?
    Ba Qiu, Xiaoxing Xie, Yanhai Xi · 2024 · Journal of Translational Medicine
  66. Roles of SIRT3 in aging and aging-related diseases
    Yuzi You, Zhong Wang · 2025 · International Journal of Biological Sciences
  67. Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating SIRT 1 activity and antioxidant gene expression in mouse cells
    Fiqri Dizar Khaidizar, Yasukazu Nakahata, Akira Kume, Kyosuke Sumizawa, Kenji Kohno, Takaaki Matsui, Yasumasa Bessho · 2017 · Genes to Cells
  68. Resveratrol attenuates excessive ethanol exposure-induced β-cell senescence in rats: A critical role for the NAD+/SIRT1-p38MAPK/p16 pathway
    Gang Luo, Lin Xiao, Dongxia Wang, Ning Wang, Can Luo, Xuefeng Yang, Liping Hao · 2020 · The Journal of Nutritional Biochemistry
  69. Attenuated SIRT1 Activity Leads to PER2 Cytoplasmic Localization and Dampens the Amplitude of Bmal1 Promoter-Driven Circadian Oscillation
    Atsushige Ashimori, Yasukazu Nakahata, Toshiya Sato, Yuichiro Fukamizu, Takaaki Matsui, Hikari Yoshitane, Yoshitaka Fukada, Kazuyuki Shinohara, Yasumasa Bessho · 2021 · Frontiers in Neuroscience
  70. Sirtuins and redox signaling interplay in neurogenesis, neurodegenerative diseases, and neural cell reprogramming
    Elisabetta Mormone, Eugenio Luigi Iorio, Lucrezia Abate, Carlo Rodolfo · 2023 · Frontiers in Neuroscience
  71. Comparative Metabolomic Profiling Reveals That Dysregulated Glycolysis Stemming from Lack of Salvage NAD+ Biosynthesis Impairs Reproductive Development in Caenorhabditis elegans
    Wenqing Wang, Melanie R. McReynolds, Jimmy F. Goncalves, Muya Shu, Ineke Dhondt, Bart P. Braeckman, Stephanie E. Lange, Kelvin Kho, Ariana C. Detwiler, Marisa J. Pacella et al. · 2015 · Journal of Biological Chemistry
  72. Altered cellular redox status, sirtuin abundance and clock gene expression in a mouse model of developmentally primed NASH
    Kimberley D. Bruce, Dawid Szczepankiewicz, Kiran K. Sihota, Manoj Ravindraanandan, Hugh Thomas, Karen A. Lillycrop, Graham C. Burdge, Mark A. Hanson, Christopher D. Byrne, Felino Ramon A. Cagampang · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  73. NMNAT1 E257K variant, associated with Leber Congenital Amaurosis (LCA9), causes a mild retinal degeneration phenotype
    Aiden Eblimit, Smriti Agrawal Zaneveld, Wei Liu, Kandace Thomas, Keqing Wang, Yumei Li, Graeme Mardon, Rui Chen · 2018 · Experimental Eye Research
  74. The evolutionary tug-of-war of macrophage metabolism during bacterial infection
    Luís Almeida, Ayesha Dhillon-LaBrooy, Tim D. Sparwasser · 2023 · Trends in Endocrinology and Metabolism
  75. Targeting NAD+ Metabolism to Modulate Autoimmunity and Inflammation
    Jing Wu, Kim Han, Michael N. Sack · 2024 · The Journal of Immunology
  76. 15-HETE protects pulmonary artery smooth muscle cells against apoptosis via SIRT1 regulation during hypoxia
    Fujun Li, Yanqiu You, Hui Fang Zhu · 2018 · Biomedicine & Pharmacotherapy
  77. Role of NUDIX Hydrolases in NAD and ADP-Ribose Metabolism in Mammals
    Veronika Kulikova, Andrey A. Nikiforov · 2020 · Biochemistry (Moscow)
  78. Targeting nicotinamide N-methyltransferase overcomes resistance to EGFR-TKI in non-small cell lung cancer cells
    Jun Wang, Xi Liu, Yuanfeng Huang, Pan Li, Minqiang Yang, Shanshan Zeng, Danyang Chen, Qian Wang, Hao Liu, Kai Luo et al. · 2022 · Cell Death Discovery
  79. Particulate matter-induced metabolic recoding of epigenetics in macrophages drives pathogenesis of chronic obstructive pulmonary disease
    Myungkyung Noh, Jeong Yeon Sim, Jisung Kim, Jee Hwan Ahn, Hye‐Young Min, Jong-Uk Lee, Jong-Sook Park, Ji Yun Jeong, Jae Young Lee, Shin Yup Lee et al. · 2023 · Journal of Hazardous Materials
  80. Reduced Ssy1-Ptr3-Ssy5 (SPS) Signaling Extends Replicative Life Span by Enhancing NAD+ Homeostasis in Saccharomyces cerevisiae
    Felicia A. Tsang, Christol James, Michiko Kato, Victoria Myers, Irtqa Ilyas, Matthew Tsang, Su-Ju Lin · 2015 · Journal of Biological Chemistry
  81. The c-MYC/NAMPT/SIRT1 feedback loop is activated in early classical and serrated route colorectal cancer and represents a therapeutic target
    Lydia Brandl, Nina Kirstein, Jens H. L. Neumann, Andrea Sendelhofert, Michael W. Vieth, Thomas Kirchner, Antje Menssen · 2018 · Medical Oncology
  82. miRNA expression profiling uncovers a role of miR‐302b‐3p in regulating skin fibroblasts senescence
    Jingyong Tan, Longyuan Hu, Xin Yang, Xin Zhang, Canshen Wei, Qing Lü, Zhilin Chen, Jing Li · 2019 · Journal of Cellular Biochemistry
  83. Metabolic Intermediates in Tumorigenesis and Progression
    Yuchen He, Menghui Gao, Haosheng Tang, Yiqu Cao, Shuang Liu, Yongguang Tao · 2019 · International Journal of Biological Sciences
  84. Inhibition of Sirt2 Alleviates Fibroblasts Activation and Pulmonary Fibrosis via Smad2/3 Pathway
    Hui Gong, Chenyi Zheng, Xing Lyu, Lini Dong, Shengyu Tan, Xiangyu Zhang · 2021 · Frontiers in Pharmacology
  85. SIRT1 activation ameliorates rhesus monkey liver fibrosis by inhibiting the TGF-β/smad signaling pathway
    Yu Xia, Qihui Luo, Qi Gao, Chao Huang, Ping Chen, Yao Zou, Xiwen Chen, Wentao Liu, Zhengli Chen · 2024 · Chemico-Biological Interactions
  86. Targeting immunosenescence for improved tumor immunotherapy
    Zaoqu Liu, Lulu Zuo, Zhaokai Zhou, Shutong Liu, Yuhao Ba, Anning Zuo, Yuqing Ren, Chuhan Zhang, Yukang Chen, Hongxuan Ma et al. · 2024 · MedComm
  87. Mesenchymal Stem Cell Senescence and Osteogenesis
    Artaria Tjempakasari, Heri Suroto, Djoko Santoso · 2021 · Medicina
  88. Mitochondrial respiratory quiescence: A new model for examining the role of mitochondrial metabolism in development
    Helin Hocaoglu, Matthew Sieber · 2022 · Seminars in Cell and Developmental Biology
  89. Fatty acids derived from apoptotic chondrocytes fuel macrophages FAO through MSR1 for facilitating BMSCs osteogenic differentiation
    Ziyang Zheng, Tao Jiang, Zhenfei Huang, Bo Chu, Jun Gu, Xuan Zhao, Hao Liu, Jin Fan, Lipeng Yu, Shu‐Heng Jiang et al. · 2022 · Redox Biology
  90. Monoterpenes as Sirtuin-1 Activators: Therapeutic Potential in Aging and Related Diseases
    Cátia Sousa, Alexandrina Ferreira Mendes · 2022 · Biomolecules
  91. NMN ameliorated radiation induced damage in NRF2-deficient cell and mice via regulating SIRT6 and SIRT7
    Xiaotong Zhao, Manman Zhang, Jinhan Wang, Kaihua Ji, Yan Wang, Xiaohui Sun, Chang Xu, Qin Wang, Ningning He, Huijuan Song et al. · 2022 · Free Radical Biology and Medicine
  92. Nicotinamide mononucleotide restores oxidative stress‐related apoptosis of oocyte exposed to benzyl butyl phthalate in mice
    Yi Jiang, Di Wang, Cheng Zhang, Yangyang Jiao, Yanan Pu, Rong Cheng, Chunyu Li, Yan Chen · 2023 · Cell Proliferation
  93. The Role of Increased Expression of Sirtuin 6 in the Prevention of Premature Aging Pathomechanisms
    Adrianna Dzidek, Olga Czerwińska‐Ledwig, Małgorzata Żychowska, Wanda Pilch, Anna Piotrowska · 2023 · International Journal of Molecular Sciences
  94. Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japanese men
    Shintaro Yamaguchi, Junichiro Irie, Masanori Mitsuishi, Yuichi Uchino, Hideaki Nakaya, Ryo Takemura, Emi Inagaki, Shotaro Kosugi, Hideyuki Okano, Masato Yasui et al. · 2024 · Endocrine Journal
  95. Finding Ponce de Leon’s Pill: Challenges in Screening for Anti-Aging Molecules
    Surinder Kumar, David B. Lombard · 2016 · F1000Research
  96. NAMPT-Mediated NAD Biosynthesis as the Internal Timing Mechanism: In NAD+ World, Time Is Running in Its Own Way
    Borut Poljšak · 2017 · Rejuvenation Research
  97. A functional link between NAD+ homeostasis and N-terminal protein acetylation in Saccharomyces cerevisiae
    Trevor Croft, Christol James Theoga Raj, Michelle Salemi, Brett S. Phinney, Su-Ju Lin · 2018 · Journal of Biological Chemistry
  98. Mitochondrial and Autophagic Regulation of Adult Neurogenesis in the Healthy and Diseased Brain
    Hansruedi Büeler · 2021 · International Journal of Molecular Sciences
  99. Early loss of endogenous NAD + following rotenone treatment leads to mitochondrial dysfunction and Sarm1 induction that is ameliorated by PARP inhibition
    Ankita Sarkar, Sourav Dutta, Malinki Sur, Semanti Chakraborty, Puja Dey, Piyali Mukherjee · 2022 · FEBS Journal
  100. Methionine in embryonic development: metabolism, redox homeostasis, epigenetic modification and signaling pathway
    Yan Chang, Biyan He, Chenjun Wang, Wanzhen Li, Siming Tao, Jingqing Chen, Yuquan Wang, Ling Yang, Yingjie Wu, Zhenlong Wu et al. · 2025 · Critical Reviews in Food Science and Nutrition