Tissue factor as a link between inflammation and coagulation

Rivaroxaban in Patients with a Recent Acute Coronary Syndrome

Mega, J. L., Braunwald, E., Wiviott, S. D., Bassand, J., Bhatt, D. L., Bode, C., Burton, P. B. J., Cohen, M. C., Cook‐Bruns, N., Fox, K. A. A., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1112277 · Cited by 1,900 · see citing works

Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

Zampetaki, A., Kiechl, S. J., Drozdov, I. A., Willeit, P., Mayr, U., Prokopi, M., Mayr, A., Weger, S., Oberhollenzer, F., Bonora, E., et al. (2010) · Circulation Research · doi:10.1161/circresaha.110.226357 · Cited by 1,457 · see citing works

Understanding alternative splicing: towards a cellular code

Matlin, A. J., Clark, F., & Smith, C. W. J. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1645 · Cited by 1,299 · see citing works

Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches

Chen, M., & Manley, J. L. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2777 · Cited by 1,284 · see citing works

Blood-borne tissue factor: Another view of thrombosis

Giesen, P. L. A., Rauch, U., Bohrmann, B., Kling, D., Roqué, M., Fallon, J. T., Badimón, J. J., Himber, J., Riederer, M. A., & Nemerson, Y. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.5.2311 · Cited by 990 · see citing works

C-reactive protein induces human peripheral blood monocytes to synthesize tissue factor

Čermák, J., Key, N., Bach, R., Balla, J., Jacob, H., & Vercellotti, G. (1993) · Blood · doi:10.1182/blood.v82.2.513.513 · Cited by 838 · see citing works

The Phosphatidylinositol 3-Kinase-Akt Pathway Limits Lipopolysaccharide Activation of Signaling Pathways and Expression of Inflammatory Mediators in Human Monocytic Cells

Guha, M., & Mackman, N. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m203298200 · Cited by 799 · see citing works

Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa

Camerer, E., Huang, W., & Coughlin, S. R. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.10.5255 · Cited by 674 · see citing works

Role of tissue factor in embryonic blood vessel development

Carmeliet, P., Mackman, N., Moons, L., Luther, T., Gressèns, P., Vlaenderen, L. V., Demunck, H., Kasper, M. E., Breier, G., Evrard, P., et al. (1996) · Nature · doi:10.1038/383073a0 · Cited by 669 · see citing works

Activation of Monocyte/Macrophage Functions Related to Acute Atheroma Complication by Ligation of CD40

Mach, F., Schönbeck, U., Bonnefoy, J., Pober, J. S., & Libby, P. (1997) · Circulation · doi:10.1161/01.cir.96.2.396 · Cited by 493 · see citing works

Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein

Bogdanov, V. Y., Balasubramanian, V., Hathcock, J. J., Vele, O. E., Lieb, M., & Nemerson, Y. (2003) · Nature Medicine · doi:10.1038/nm841 · Cited by 467 · see citing works

MicroRNA-181b regulates NF-κB–mediated vascular inflammation

Sun, X., Icli, B., Wara, A. K., Belkin, N., He, S., Kobzik, L., Hunninghake, G. M., Pinilla-Vera, M., Blackwell, T. S., Baron, R. M., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci61495 · Cited by 450 · see citing works

The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation

Anczuków, O., Rosenberg, A. Z., Akerman, M., Das, S., Zhan, L., Karni, R., Muthuswamy, S. K., & Krainer, A. R. (2012) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2207 · Cited by 441 · see citing works

Transfer of tissue factor from leukocytes to platelets is mediated by CD15 and tissue factor

Rauch, U., Bonderman, D., Bohrmann, B., Badimón, J. J., Himber, J., Riederer, M. A., & Nemerson, Y. (2000) · Blood · doi:10.1182/blood.v96.1.170.013k42_170_175 · Cited by 419 · see citing works

Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets

Müller, I., Klocke, A., Alex, M., Kotzsch, M., Luther, T., Morgenstern, E., Zieseniss, S., Stefan Zahler, A., Preissner, K., & Engelmann, B. (2003) · The FASEB Journal · doi:10.1096/fj.02-0574fje · Cited by 401 · see citing works

Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody

Fleck, R. A., Rao, L. V. M., Rapaport, S. I., & Varki, N. M. (1990) · Thrombosis Research · doi:10.1016/0049-3848(90)90148-6 · Cited by 361 · see citing works

Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenecity of human platelets

Schwertz, H., Tolley, N. D., Foulks, J. M., Denis, M. M., Risenmay, B. W., Buerke, M., Tilley, R. E., Rondina, M. T., Harris, E. M., Kraiss, L. W., et al. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20061302 · Cited by 361 · see citing works

Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation

Chou, J., Mackman, N., Merrill‐Skoloff, G., Pedersen, B., Furie, B. C., & Furie, B. (2004) · Blood · doi:10.1182/blood-2004-03-0935 · Cited by 347 · see citing works

Statin Prevents Tissue Factor Expression in Human Endothelial Cells

Eto, M., Kozai, T., Cosentino, F., Joch, H., & Lüscher, T. F. (2002) · Circulation · doi:10.1161/01.cir.0000015465.73933.3b · Cited by 331 · see citing works

Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia

Pawliński, R., Pedersen, B., Schabbauer, G., Tencati, M., Holscher, T. D., Boisvert, W. A., Andrade‐Gordon, P., Frank, R. D., & Mackman, N. (2003) · Blood · doi:10.1182/blood-2003-09-3051 · Cited by 308 · see citing works

Thrombus Formation on Atherosclerotic Plaques: Pathogenesis and Clinical Consequences

Rauch, U., Osende, J. I., Fuster, V., Badimón, J. J., Fayad, Z. A., & Chesebro, J. H. (2001) · Annals of Internal Medicine · doi:10.7326/0003-4819-134-3-200102060-00014 · Cited by 297 · see citing works

Thrombin Responses in Human Endothelial Cells

O'Brien, P. J., Prévost, N., Molino, M., Hollinger, M. K., Woolkalís, M. J., Woulfe, D. S., & Brass, L. F. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.18.13502 · Cited by 297 · see citing works

Procoagulant Soluble Tissue Factor Is Released From Endothelial Cells in Response to Inflammatory Cytokines

Szotowski, B., Antoniak, S., Poller, W. C., Schultheiss, H., & Rauch, U. (2005) · Circulation Research · doi:10.1161/01.res.0000171805.24799.fa · Cited by 293 · see citing works

Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall

Day, S. M., Reeve, J., Pedersen, B., Farris, D. M., Myers, D. D., Im, M. M., Wakefield, T. W., Mackman, N., & Fay, W. P. (2004) · Blood · doi:10.1182/blood-2004-06-2225 · Cited by 281 · see citing works

Regulation of the Tissue Factor Gene

Mackman, N. (1997) · Thrombosis and Haemostasis · doi:10.1055/s-0038-1657623 · Cited by 274 · see citing works

Minimally oxidized low-density lipoprotein induces tissue factor expression in cultured human endothelial cells.

Drake, T. A., Hannani, K. K., Fei, H. H., Lavi, S., & Berliner, J. A. (1991) · PubMed Central · Cited by 223 · see citing works

Low levels of tissue factor are compatible with development and hemostasis in mice.

Parry, G. C., Erlich, J., Carmeliet, P., Luther, T., & Mackman, N. (1998) · Journal of Clinical Investigation · doi:10.1172/jci814 · Cited by 202 · see citing works

Let-7 in Cardiovascular Diseases, Heart Development and Cardiovascular Differentiation from Stem Cells

Bao, M., Xing, F., Zhang, Y., Lou, X.-Y., Cheng, Y., & Zhou, H. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms141123086 · Cited by 195 · see citing works

Factor Xa Induces Cytokine Production and Expression of Adhesion Molecules by Human Umbilical Vein Endothelial Cells

Senden, N. H. M., Jeunhomme, T. M. A. A., Heemskerk, J. W. M., Wagenvoord, R. J., Veer, C. V. ′., Hemker, H. C., & Buurman, W. A. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.8.4318 · Cited by 192 · see citing works

Hypoxia/Hypoxemia-Induced Activation of the Procoagulant Pathways and the Pathogenesis of Ischemia-Associated Thrombosis

Yan, S.-F., Mackman, N., Kisiel, W., Stern, D. M., & Pinsky, D. J. (1999) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.19.9.2029 · Cited by 185 · see citing works

Specificity, diversity, and convergence in VEGF and TNF‐α signaling events leading to tissue factor up regulation via EGR‐1 in endothelial cells

Mechtcheriakova, D., Schabbauer, G., Lucerna, M., Clauss, M. A., de Martin, R., Binder, B. R., & Hofer, E. (2001) · The FASEB Journal · doi:10.1096/fj.00-0247com · Cited by 182 · see citing works

Blood thrombogenicity in type 2 diabetes mellitus patients is associated with glycemic control

Osende, J. I., Badimon, J. J., Fuster, V., Herson, P., Rabito, P., Vidhun, R., Zaman, A., Rodriguez, O. J., Lev, E. I., Rauch, U., et al. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(01)01555-8 · Cited by 167 · see citing works

Alternatively spliced tissue factor induces angiogenesis through integrin ligation

van den Berg, Y. W., van den Hengel, L. G., Myers, H. R., Ayachi, O., Jordanova, E. S., Ruf, W., Spek, C. A., Reitsma, P. H., Bogdanov, V. Y., & Versteeg, H. H. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0905325106 · Cited by 150 · see citing works

Shedding of tissue factor (TF)‐containing microparticles rather than alternatively spliced TF is the main source of TF activity released from human cancer cells

Yu, J., & Rak, J. W. (2004) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2004.00972.x · Cited by 149 · see citing works

Structure of the Extracellular Domain of Human Tissue Factor: Location of the Factor VIIa Binding Site

Muller, Y. A., Ultsch, M. H., Kelley, R. F., & de Vos, A. M. (1994) · Biochemistry · doi:10.1021/bi00202a003 · Cited by 144 · see citing works

Fibrinogen and fibrin induce synthesis of proinflammatory cytokines from isolated peripheral blood mononuclear cells

Kierulf, P., Sandset, P. M., Klingenberg, O., Joø, G. B., Godal, H. C., Skjønsberg, O. H., & Jensen, T. (2007) · Thrombosis and Haemostasis · doi:10.1160/th07-01-0039 · Cited by 140 · see citing works

Protease-activated Receptor 2-dependent Phosphorylation of the Tissue Factor Cytoplasmic Domain

Ahamed, J., & Ruf, W. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m401376200 · Cited by 139 · see citing works

Histamine Induces Tissue Factor Expression

Steffel, J., Akhmedov, A., Greutert, H., Lüscher, T. F., & Tanner, F. C. (2005) · Circulation · doi:10.1161/circulationaha.105.553735 · Cited by 132 · see citing works

MicroRNA-19 (miR-19) Regulates Tissue Factor Expression in Breast Cancer Cells

Zhang, X., Yu, H., Lou, J. R., Zheng, J., Zhu, H., Popescu, N. I., Lupu, F., Lind, S. E., & Ding, W. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.146530 · Cited by 132 · see citing works

Identification of miRNAs as potential modulators of tissue factor expression in patients with systemic lupus erythematosus and antiphospholipid syndrome

Teruel, R., Pérez-Sánchez, C., Corral, J., Herranz, M. T., Pérez-Andreu, V., Saiz, E., García-Barberá, N., Martínez-Martínez, I., Roldán, V., Vicente, V., et al. (2011) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2011.04451.x · Cited by 120 · see citing works

Tissue Factor: Then and Now

Nemerson, Y. (1995) · Thrombosis and Haemostasis · doi:10.1055/s-0038-1642673 · Cited by 116 · see citing works

Thrombin and factor Xa enhance the production of interleukin-1.

Jones, A., & Geczy, C. L. (1990) · PubMed Central · Cited by 112 · see citing works

Monocytes Upregulate Endothelial Cell Expression of Tissue Factor: A Role for Cell-Cell Contact and Cross-Talk

Napoleone, E., Santo, A. D., & Lorenzet, R. (1997) · Blood · doi:10.1182/blood.v89.2.541 · Cited by 112 · see citing works

Heterogeneous regulation of constitutive thrombomodulin or inducible tissue-factor activities on the surface of human saphenous-vein endothelial cells in culture following stimulation by interleukin-1, tumour necrosis factor, thrombin or phorbol ester

Archipoff, G., Beretz, A., Freyssinet, J., Klein-Soyer, C., Brisson, C., & Cazenave, J. (1991) · Biochemical Journal · doi:10.1042/bj2730679 · Cited by 110 · see citing works

Celecoxib Decreases Endothelial Tissue Factor Expression Through Inhibition of c-Jun Terminal NH 2 Kinase Phosphorylation

Steffel, J., Hermann, M., Greutert, H., Gay, S., Lüscher, T. F., Ruschitzka, F. T., & Tanner, F. C. (2005) · Circulation · doi:10.1161/01.cir.0000160358.63804.c9 · Cited by 110 · see citing works

Circulating tissue factor and thrombosis

Rauch, U., & Nemerson, Y. (2000) · Current Opinion in Hematology · doi:10.1097/00062752-200009000-00003 · Cited by 108 · see citing works

Cooperation Between VEGF and TNF-α Is Necessary for Exposure of Active Tissue Factor on the Surface of Human Endothelial Cells

Camera, M., Giesen, P. L. A., Fallon, J., Aufiero, B. M., Taubman, M. B., Tremoli, E., & Nemerson, Y. (1999) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.19.3.531 · Cited by 106 · see citing works

Vascular smooth muscle–derived tissue factor is critical for arterial thrombosis after ferric chloride–induced injury

Wang, L., Miller, C., Swarthout, R. F., Rao, M., Mackman, N., & Taubman, M. B. (2008) · Blood · doi:10.1182/blood-2007-05-090944 · Cited by 103 · see citing works

miR-93/106b and Their Host Gene, MCM7, Are Differentially Expressed in Leiomyomas and Functionally Target F3 and IL-8

Chuang, T., Luo, X., Panda, H., & Chegini, N. (2012) · Molecular Endocrinology · doi:10.1210/me.2012-1075 · Cited by 100 · see citing works

Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction

Pawliński, R., Fernandes, A., Kehrle, B., Pedersen, B., Parry, G. C., Erlich, J., Pyo, R. T., Gutstein, D. E., Zhang, J., Castellino, F. J., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242501899 · Cited by 98 · see citing works

Tissue Factor, the Blood, and the Arterial Wall

Rauch, U. (2000) · Trends in Cardiovascular Medicine · doi:10.1016/s1050-1738(00)00049-9 · Cited by 98 · see citing works

Vascular Endothelial Growth Factor Production by Fibroblasts in Response to Factor VIIa Binding to Tissue Factor Involves Thrombin and Factor Xa

Ollivier, V., Chabbat, J., Herbert, J., Hakim, J., & de Prost, D. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.5.1374 · Cited by 85 · see citing works

Tissue factor expression pattern in human non-small cell lung cancer tissues indicate increased blood thrombogenicity and tumor metastasis

Goldin-Lang, P., Tran, Q.-V., Fichtner, I., Eisenreich, A., Antoniak, S., Schulze, K., Coupland, S. E., Poller, W. C., Schultheiss, H., & Rauch, U. (2008) · Oncology Reports · doi:10.3892/or.20.1.123 · Cited by 83 · see citing works

Cdc2-Like Kinases and DNA Topoisomerase I Regulate Alternative Splicing of Tissue Factor in Human Endothelial Cells

Eisenreich, A., Bogdanov, V. Y., Zakrzewicz, A., Pries, A. R., Antoniak, S., Poller, W. C., Schultheiß, H., & Rauch, U. (2009) · Circulation Research · doi:10.1161/circresaha.108.183905 · Cited by 81 · see citing works

Alterations in myocardial tissue factor expression and cellular localization in dilated cardiomyopathy

Szotowski, B., Goldin-Lang, P., Antoniak, S., Bogdanov, V. Y., Pathirana, D., Pauschinger, M., Dörner, A., Kühl, U., Coupland, S. E., Nemerson, Y., et al. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.12.061 · Cited by 80 · see citing works

MicroRNA-223 inhibits tissue factor expression in vascular endothelial cells

Li, S., Chen, H., Ren, J., Geng, Q., Song, J., Lee, C., Cao, C., Zhang, J., & Xu, N. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.09.033 · Cited by 78 · see citing works

Inhibition of tissue factor reduces thrombus formation and intimal hyperplasia after porcine coronary angioplasty

Roqué, M., Reis, E. D., Fuster, V., Padurean, A. M., Fallon, J. T., Taubman, M. B., Chesebro, J. H., & Badimón, J. J. (2000) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)01018-4 · Cited by 73 · see citing works

Protease-Activated Receptor-2 Modulates Protease-Activated Receptor-1–Driven Neointimal Hyperplasia

Sevigny, L. M., Austin, K. M., Zhang, P., Kasuda, S., Κούκος, Γ., Sharifi, S., Covic, L., & Kuliopulos, A. (2011) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.111.238261 · Cited by 71 · see citing works

Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1

Fernández, J. A., Griffin, J. H., Schuepbach, R. A., Feistritzer, C., & Riewald, M. (2009) · Thrombosis and Haemostasis · doi:10.1160/th08-10-0632 · Cited by 70 · see citing works

MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor

Li, S., Ren, J., Xu, N., Zhang, J., Geng, Q., Cao, C., Lee, C., Song, J., Li, J., & Chen, H. (2014) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2014.06.017 · Cited by 70 · see citing works

Direct thrombin inhibitors, but not the direct factor Xa inhibitor rivaroxaban, increase tissue factor‐induced hypercoagulability in vitro and in vivo

Perzborn, E., Heitmeier, S., Buetehorn, U., & Laux, V. (2014) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.12591 · Cited by 68 · see citing works

Alternatively spliced tissue factor promotes breast cancer growth in a β1 integrin-dependent manner

Kocatürk, B., van den Berg, Y. W., Tieken, C., Mieog, J. S. D., de Kruijf, E. M., Engels, C. C., van der Ent, M. A., Kuppen, P. J. K., van de Velde, C. J., Ruf, W., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1307100110 · Cited by 66 · see citing works

Low levels of tissue factor lead to alveolar haemorrhage, potentiating murine acute lung injury and oxidative stress

Bastarache, J. A., Sebag, S. C., Clune, J. K., Grove, B. S., Lawson, W. E., Janz, D. R., Roberts, L. J., Dworski, R., Mackman, N., & Ware, L. B. (2012) · Thorax · doi:10.1136/thoraxjnl-2012-201781 · Cited by 65 · see citing works

Splice variants of tissue factor promote monocyte‐endothelial interactions by triggering the expression of cell adhesion molecules via integrin‐mediated signaling

Srinivasan, R., Ozhegov, E., van den Berg, Y. W., Aronow, B. J., FRANCO, R. S., Palascak, M. B., Fallon, J. T., Ruf, W., Versteeg, H. H., & Bogdanov, V. Y. (2011) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2011.04454.x · Cited by 64 · see citing works

MicroRNA-19a targets tissue factor to inhibit colon cancer cells migration and invasion

Yu, G., Li, H., Wang, X., Wu, T., Zhu, J., Huang, S., Wan, Y., & Tang, J. (2013) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-013-1679-6 · Cited by 57 · see citing works

Serotonin induces the expression of tissue factor and plasminogen activator inhibitor-1 in cultured rat aortic endothelial cells

Kawano, H., Tsuji, H., Nishimura, H., Kimura, S., Yano, S., Ukimura, N., Kunieda, Y., Yoshizumi, M., Sugano, T., Nakagawa, K., et al. (2001) · Blood · doi:10.1182/blood.v97.6.1697 · Cited by 57 · see citing works

Angiotensin II induces the expression of tissue factor and its mechanism in human monocytes

He, M., He, X., Xie, Q.-Z., Chen, F., & He, S. (2005) · Thrombosis Research · doi:10.1016/j.thromres.2005.04.033 · Cited by 55 · see citing works

FXa-Induced Responses in Vascular Wall Cells are PAR-Mediated and Inhibited by ZK-807834

Mclean, K., Schirm, S., Johns, A., Morser, J., & Light, D. R. (2001) · Thrombosis Research · doi:10.1016/s0049-3848(01)00330-9 · Cited by 52 · see citing works

Identification and characterization of murine alternatively spliced tissue factor

Bogdanov, V. Y., Kirk, R. I., Miller, C. L., Hathcock, J. J., VELE, S., Gazdoiu, M., Nemerson, Y., & Taubman, M. B. (2005) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2005.01680.x · Cited by 51 · see citing works

Role of the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway in Regulating Alternative Splicing of Tissue Factor mRNA in Human Endothelial Cells

Eisenreich, A., Malz, R., Pepke, W., Ayral, Y., Poller, W. C., Schultheiss, H., & Rauch, U. (2009) · Circulation Journal · doi:10.1253/circj.cj-99-0225 · Cited by 50 · see citing works

Increased thrombus formation relates to ambient blood glucose and leukocyte count in diabetes mellitus type 2

Rauch, U., Crandall, J. P., Osende, J. I., Fallon, J. T., Chesebro, J. H., Fuster, V., & Badimon, J. (2000) · The American Journal of Cardiology · doi:10.1016/s0002-9149(00)00871-7 · Cited by 48 · see citing works

Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells

Eisenreich, A., Zakrzewicz, A., Huber, K., THIERBACH, H., Pepke, W., Goldin-Lang, P., Schultheiß, H., Pries, A. R., & Rauch, U. (2013) · Oncology Reports · doi:10.3892/or.2013.2413 · Cited by 47 · see citing works

Alternatively Spliced Tissue Factor: A Previously Unknown Piece in the Puzzle of Hemostasis

Szotowski, B., Antoniak, S., & Rauch, U. (2006) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2006.03.005 · Cited by 46 · see citing works

Pathogenesis of Thrombosis in Coronary Artery Disease

Chesebro, J. H., Rauch, U., Fuster, V., & Badimon, J. J. (2009) · Haemostasis · doi:10.1159/000217477 · Cited by 43 · see citing works

Alternatively spliced tissue factor and full-length tissue factor protect cardiomyocytes against TNF-α-induced apoptosis

Boltzen, U., Eisenreich, A., Antoniak, S., Weithäuser, A., Fechner, H., Poller, W. C., Schultheiß, H., Mackman, N., & Rauch, U. (2012) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2012.01.015 · Cited by 42 · see citing works

Tissue factor-positive microparticles in blood associated with coagulopathy in cancer

Antoniak, S., & Rauch, U. (2007) · Thrombosis and Haemostasis · doi:10.1160/th06-12-0687 · Cited by 41 · see citing works

CRP regulates the expression and activity of tissue factor as well as tissue factor pathway inhibitor via NF‐κB and ERK 1/2 MAPK pathway

Chen, Y., Wang, J., Yao, Y.-J., Yuan, W., Kong, M., Lin, Y., Geng, D.-F., & Nie, R. (2009) · FEBS Letters · doi:10.1016/j.febslet.2009.07.037 · Cited by 41 · see citing works

Microparticle association and heterogeneity of tumor‐derived tissue factor in plasma: is it important for coagulation activation?

Davila, M., Robles-Carrillo, L. D., Unruh, D. J., Huo, Q., Gardiner, C., Sargent, I. L., Adam, M., Woodhams, B. J., Francis, J. L., Bogdanov, V. Y., et al. (2013) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.12475 · Cited by 36 · see citing works

Association of tissue-factor upregulation in squamous-cell carcinoma of the lung with increased tissue factor in circulating blood

Rauch, U., Antoniak, S., Boots, M., Schulze, K., Goldin-Lang, P., Stein, H., Schultheiß, H., & Coupland, S. E. (2005) · The Lancet Oncology · doi:10.1016/s1470-2045(05)70099-1 · Cited by 33 · see citing works

SR proteins ASF/SF2 and SRp55 participate in tissue factor biosynthesis in human monocytic cells

Tardos, J. G., Eisenreich, A., Deikus, G. Y., Bechhofer, D. H., Chandradas, S., Zafar, M. U., Rauch, U., & Bogdanov, V. Y. (2008) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2008.02946.x · Cited by 30 · see citing works

Ionizing radiation induces upregulation of cellular procoagulability and tissue factor expression in human peripheral blood mononuclear cells

Goldin-Lang, P., Niebergall, F., Antoniak, S., Szotowski, B., Rosenthal, P., Pels, K., Schultheiß, H., & Rauch, U. (2007) · Thrombosis Research · doi:10.1016/j.thromres.2007.01.008 · Cited by 28 · see citing works

MicroRNA-19a regulates lipopolysaccharide-induced endothelial cell apoptosis through modulation of apoptosis signal-regulating kinase 1 expression

Jiang, W., Zhang, Y., Xia, Q., Zhu, J., Yu, X., Fan, T. T., & Wang, F. (2015) · BMC Molecular Biology · doi:10.1186/s12867-015-0034-8 · Cited by 28 · see citing works

Possible involvement of p21/waf1 in the growth inhibition of HepG2 cells induced by hepatocyte growth factor

Shima, N., Stolz, D. B., Miyazaki, M., Gohda, E., Higashio, K., & Michalopoulos, G. K. (1998) · Journal of Cellular Physiology · doi:10.1002/(sici)1097-4652(199810)177:1 · Cited by 26 · see citing works

Regulation and Differential Role of the Tissue Factor Isoforms in Cardiovascular Biology

Eisenreich, A., & Rauch, U. (2010) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2011.08.001 · Cited by 23 · see citing works

Risk of Intracranial Hemorrhage With Protease-Activated Receptor-1 Antagonists

Lee, M., Saver, J. L., Hong, K., Wu, H., & Ovbiagele, B. I. (2012) · Stroke · doi:10.1161/strokeaha.112.670604 · Cited by 22 · see citing works

Levels of Alternatively Spliced Tissue Factor in the Plasma of Patients with Pancreatic Cancer May Help Predict Aggressive Tumor Phenotype

Unruh, D. J., Sagin, F., Adam, M., Dreden, P. V., Woodhams, B. J., Hart, K. W., Lindsell, C. J., Ahmad, S. A., & Bogdanov, V. Y. (2015) · Annals of Surgical Oncology · doi:10.1245/s10434-015-4592-2 · Cited by 22 · see citing works

Alternatively Spliced Tissue Factor Is Not Sufficient for Embryonic Development

Sluka, S. H. M., Akhmedov, A., Vogel, J., Unruh, D. J., Bogdanov, V. Y., Camici, G. G., Lüscher, T. F., Ruf, W., & Tanner, F. C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0097793 · Cited by 8 · see citing works

Gut microbiota and cardiovascular disease.

Witkowski, M., Weeks, T. L., & Hazen, S. L. (2020) · Circulation Research · doi:10.1161/circresaha.120.316242 · Cited by 1,051 · see citing works

Tissue Factor

Grover, S. P., & Mackman, N. (2018) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.117.309846 · Cited by 672 · see citing works

Intravascular Mesenchymal Stromal/Stem Cell Therapy Product Diversification: Time for New Clinical Guidelines

Moll, G., Ankrum, J. A., Kamhieh-Milz, J., Bieback, K., Ringdén, O., Volk, H.-D., Geissler, S., & Reinke, P. (2019) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2018.12.006 · Cited by 440 · see citing works

Risk Factors Associated With Clinical Outcomes in 323 Coronavirus Disease 2019 (COVID-19) Hospitalized Patients in Wuhan, China

Hu, L., Chen, S., Fu, Y., Gao, Z., Long, H., Ren, H., Zuo, Y., Li, H., Wang, J., Yu, W.-X., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa539 · Cited by 398 · see citing works

The Therapeutic Potential of Mesenchymal Stromal Cells for Regenerative Medicine: Current Knowledge and Future Understandings

Merimi, M., Majzoub, R. E., Lagneaux, L., Agha, D. M., Bouhtit, F., Meuleman, N., Fahmi, H., Lewalle, P., Fayyad‐Kazan, M., & Najar, M. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.661532 · Cited by 180 · see citing works

Improved MSC Minimal Criteria to Maximize Patient Safety: A Call to Embrace Tissue Factor and Hemocompatibility Assessment of MSC Products

Moll, G., Ankrum, J. A., Olson, S. D., & Nolta, J. A. (2022) · Stem Cells Translational Medicine · doi:10.1093/stcltm/szab005 · Cited by 176 · see citing works

Macrophage activation syndrome and COVID-19

Otsuka, R., & Seino, K.-I. (2020) · Inflammation and Regeneration · doi:10.1186/s41232-020-00131-w · Cited by 139 · see citing works

Reactions Related to CAR-T Cell Therapy

Miao, L., Zhang, Z., Ren, Z., & Li, Y. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.663201 · Cited by 124 · see citing works

Microvascular thrombosis: experimental and clinical implications

Bray, M. A., Sartain, S. E., Gollamudi, J., & Rumbaut, R. E. (2020) · Translational research · doi:10.1016/j.trsl.2020.05.006 · Cited by 119 · see citing works

Beyond thrombosis: the impact of tissue factor signaling in cancer

Unruh, D. J., & Horbinski, C. (2020) · Journal of Hematology & Oncology · doi:10.1186/s13045-020-00932-z · Cited by 117 · see citing works

Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis

Witkowski, M., Witkowski, M., Friebel, J., Buffa, J. A., Li, X. S., Wang, Z., Sangwan, N., Li, L., DiDonato, J. A., Tizian, C., et al. (2021) · Cardiovascular Research · doi:10.1093/cvr/cvab263 · Cited by 116 · see citing works

Endothelial cells: source, barrier, and target of defensive mediators

Roumenina, L. T., Rayes, J., Frimat, M., & Frémeaux‐Bacchi, V. (2016) · Immunological Reviews · doi:10.1111/imr.12479 · Cited by 107 · see citing works

Hypercoagulopathy and Adipose Tissue Exacerbated Inflammation May Explain Higher Mortality in COVID-19 Patients With Obesity

Pasquarelli-do-Nascimento, G., Braz-de-Melo, H. A., Faria, S. S., Santos, I. D. O., Kobinger, G., & Magalhães, K. G. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00530 · Cited by 99 · see citing works

Intravenous Infusion of Human Adipose Mesenchymal Stem Cells Modifies the Host Response to Lipopolysaccharide in Humans: A Randomized, Single-Blind, Parallel Group, Placebo Controlled Trial

Perlee, D., van Vught, L. A., Scicluna, B. P., Maag, A., Lutter, R., Kemper, E. M., Veer, C. V. ′., Punchard, M. A., González, J., Richard, M. P., et al. (2018) · Stem Cells · doi:10.1002/stem.2891 · Cited by 99 · see citing works

From Infection to Death: An Overview of the Pathogenesis of Visceral Leishmaniasis

Costa, C. H. N., Chang, K. P., Costa, D. L., & Cunha, F. V. M. (2023) · Pathogens · doi:10.3390/pathogens12070969 · Cited by 109 · see citing works

Micro–RNA-126 Reduces the Blood Thrombogenicity in Diabetes Mellitus via Targeting of Tissue Factor

Witkowski, M., Weithauser, A., Tabaraie, T., Steffens, D., Kränkel, N., Witkowski, M., Stratmann, B., Tschoepe, D., Landmesser, U., & Rauch-Kroehnert, U. (2016) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.115.306094 · Cited by 79 · see citing works

The interplay between hemostasis and immune response in biomaterial development for osteogenesis

Xiao, L., Ma, Y., Crawford, R., Mendhi, J., Zhang, Y., Lu, H., Zhao, Q., Cao, J., Wu, C., Wang, X., et al. (2022) · Materials Today · doi:10.1016/j.mattod.2022.02.010 · Cited by 75 · see citing works

The molecular basis for the prothrombotic state in sickle cell disease

Shet, A. S., Lizarralde-Iragorri, M. A., & Naik, R. P. P. (2020) · Haematologica · doi:10.3324/haematol.2019.239350 · Cited by 72 · see citing works

Balancing Microthrombosis and Inflammation via Injectable Protein Hydrogel for Inflammatory Bowel Disease

Hong, L., Chen, G., Cai, Z., Liu, H., Zhang, C., Wang, F., Xiao, Z., Zhong, J., Wang, L., Wang, Z., et al. (2022) · Advanced Science · doi:10.1002/advs.202200281 · Cited by 73 · see citing works

Thrombin, a Mediator of Coagulation, Inflammation, and Neurotoxicity at the Neurovascular Interface: Implications for Alzheimer’s Disease

Iannucci, J., Renehan, W. E., & Grammas, P. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00762 · Cited by 72 · see citing works

Molecular Insights Into SARS COV-2 Interaction With Cardiovascular Disease: Role of RAAS and MAPK Signaling

Wehbe, Z., Hammoud, S. H., Soudani, N., Zaraket, H., EL‐Yazbi, A. F., & Eid, A. H. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00836 · Cited by 70 · see citing works

Coagulopathy and thromboembolic events in patients with SARS-CoV-2 infection: pathogenesis and management strategies

Allegra, A., Innao, V., Allegra, A. G., & Musolino, C. (2020) · Annals of Hematology · doi:10.1007/s00277-020-04182-4 · Cited by 67 · see citing works

COVID-19 and coagulative axis: review of emerging aspects in a novel disease

Boccia, M., Aronne, L., Celia, B., Mazzeo, G., Ceparano, M., D’Agnano, V., Parrella, R., Valente, T., Bianco, A., & Perrotta, F. (2020) · Monaldi Archives for Chest Disease · doi:10.4081/monaldi.2020.1300 · Cited by 66 · see citing works

Mesenchymal stem cell immunomodulation: in pursuit of controlling COVID-19 related cytokine storm

Song, N., Wakimoto, H., Rossignoli, F., Bhere, D., Ciccocioppo, R., Chen, K.-S., Khalsa, J. K., Mastrolia, I., Samarelli, A. V., Dominici, M., et al. (2021) · Stem Cells · doi:10.1002/stem.3354 · Cited by 62 · see citing works

[Characteristics, causes, diagnosis and treatment of coagulation dysfunction in patients with COVID-19].

Mei, H., & Hu, Y. (2020) · PubMed Central · doi:10.3760/cma.j.issn.0253-2727.2020.0002 · Cited by 61 · see citing works

Extracellular vesicles released in response to respiratory exposures: implications for chronic disease

Benedikter, B. J., Wouters, E. F. �., Savelkoul, P. H. M., Rohde, G. G. U., & Stassen, F. R. M. (2018) · Journal of Toxicology and Environmental Health Part B · doi:10.1080/10937404.2018.1466380 · Cited by 59 · see citing works

Thrombotic manifestations of VEXAS syndrome

Groarke, E. M., Dulau‐Florea, A., & Kanthi, Y. M. (2021) · Seminars in Hematology · doi:10.1053/j.seminhematol.2021.10.006 · Cited by 55 · see citing works

PCSK9 Induces Tissue Factor Expression by Activation of TLR4/NFkB Signaling

Scalise, V., Sanguinetti, C., Neri, T., Cianchetti, S., Lai, M., Carnicelli, V., Celi, A., & Pedrinelli, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222312640 · Cited by 55 · see citing works

The SIRT1 inhibitor EX-527 suppresses mTOR activation and alleviates acute lung injury in mice with endotoxiemia

Huang, J., Tian, R., Yang, Y., Jiang, R., Dai, J., Tang, L. P., & Zhang, L. (2017) · Innate Immunity · doi:10.1177/1753425917733531 · Cited by 53 · see citing works

A new perspective on cerebrospinal fluid dynamics after subarachnoid hemorrhage: From normal physiology to pathophysiological changes

Fang, Y., Huang, L., Wang, X., Si, X., Lenahan, C., Shi, H., Shao, A., Tang, J., Chen, S., Zhang, J., et al. (2021) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x211045748 · Cited by 52 · see citing works

The intersection of coagulation activation and inflammation after injury: What you need to know

Costantini, T. W., Kornblith, L. Z., Pritts, T. A., & Coimbra, R. S. M. (2023) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0000000000004190 · Cited by 52 · see citing works

Protease-Activated Receptor PAR-4: An Inducible Switch between Thrombosis and Vascular Inflammation?

Fender, A. C., Rauch, B. H., Geisler, T., & Schrör, K. (2017) · Thrombosis and Haemostasis · doi:10.1160/th17-03-0219 · Cited by 50 · see citing works

Vascular miR-181b controls tissue factor-dependent thrombogenicity and inflammation in type 2 diabetes

Witkowski, M., Witkowski, M., Saffarzadeh, M., Friebel, J., Tabaraie, T., Ta Bao, L., Chakraborty, A., Dörner, A., Stratmann, B., Tschoepe, D., et al. (2020) · Cardiovascular Diabetology · doi:10.1186/s12933-020-0993-z · Cited by 50 · see citing works

HIV-related cardiovascular diseases: the search for a unifying hypothesis

Dominick, L., Midgley, N., Swart, L.-M., Sprake, D., Deshpande, G., Laher, I., Joseph, D. E., Teer, E., & Essop, M. F. (2020) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00549.2019 · Cited by 51 · see citing works

Mesenchymal stem cells biological and biotechnological advances: Implications for clinical applications

Pharoun, J., Berro, J., Sobh, J., Abou-Younes, M.-M., Nasr, L., Majed, A., Khalil, A., Joseph, J., Stephan, & Faour, W. H. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176719 · Cited by 53 · see citing works

Proteomic analysis reveals procoagulant properties of cigarette smoke‐induced extracellular vesicles

Benedikter, B. J., Bouwman, F. G., Heinzmann, A. C. A., Vajen, T., Mariman, E. C. M., Wouters, E. F. �., Savelkoul, P. H. M., Koenen, R. R., Rohde, G. G. U., van Oerle, R., et al. (2019) · Journal of Extracellular Vesicles · doi:10.1080/20013078.2019.1585163 · Cited by 47 · see citing works

COVID‐19‐related coagulopathy: A review of pathophysiology and pharmaceutical management

Vajari, M. K., Shirin, M., Pourbagheri‐Sigaroodi, A., Akbari, M. E., Abolghasemi, H., & Bashash, D. (2021) · Cell Biology International · doi:10.1002/cbin.11623 · Cited by 48 · see citing works

Coagulation cascade and complement system in systemic lupus erythematosus

Liang, Y., Xie, S., Wu, C., Hu, Y., Zhang, Q., Li, S., Fan, Y., Leng, R., Pan, H., Xiong, H., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.23206 · Cited by 46 · see citing works

Sickle Cell Disease: A Paradigm for Venous Thrombosis Pathophysiology

Lizarralde-Iragorri, M. A., & Shet, A. S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21155279 · Cited by 45 · see citing works

Post-stroke Impairment of the Blood–Brain Barrier and Perifocal Vasogenic Edema Is Alleviated by Endovascular Mesenchymal Stem Cell Administration: Modulation of the PKCδ/MMP9/AQP4-Mediated Pathway

Datta, A., Sarmah, D., Kaur, H., Chaudhary, A., Mounica, L., Kalia, K., Borah, A., Yavagal, D. R., & Bhattacharya, P. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-02761-2 · Cited by 44 · see citing works

Mechanisms and interactions in concomitant use of herbs and warfarin therapy: An updated review

Leite, P. M., Martins, M. A. P., Ferriani, M. D. G. C., & Castilho, R. O. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112103 · Cited by 43 · see citing works

When Origin Matters: Properties of Mesenchymal Stromal Cells From Different Sources for Clinical Translation in Kidney Disease

Calcat-i-Cervera, S., Sanz‐Nogués, C., & O’Brien, T. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.728496 · Cited by 42 · see citing works

NLRP3 inflammasome contributes to endotoxin-induced coagulation

Shi, J., Tang, Y., Liang, F., Liu, L., Liang, N., Yang, X., Zhang, N., Yi, Z., Zhong, Y., Wang, W., et al. (2022) · Thrombosis Research · doi:10.1016/j.thromres.2022.04.001 · Cited by 39 · see citing works

Thrombin, a Key Driver of Pathological Inflammation in the Brain

Iannucci, J., & Grammas, P. (2023) · Cells · doi:10.3390/cells12091222 · Cited by 38 · see citing works

Withametelin: a biologically active withanolide in cancer, inflammation, pain and depression

Baig, M. W., Nasir, B., Waseem, D., Majid, M., Khan, M. Z. I., & Haq, I. (2020) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2020.09.021 · Cited by 38 · see citing works

ICAM-1–targeted thrombomodulin mitigates tissue factor–driven inflammatory thrombosis in a human endothelialized microfluidic model

Greineder, C. F., Johnston, I. H., Villa, C. H., Gollomp, K. L., Esmon, C. T., Cines, D. B., Poncz, M., & Muzykantov, V. R. (2017) · Blood Advances · doi:10.1182/bloodadvances.2017007229 · Cited by 37 · see citing works

Tissue factor (:Factor VIIa) in the heart and vasculature: More than an envelope

D’Alessandro, E., Posma, J., Spronk, H. M. H., & Cate, H. T. (2018) · Thrombosis Research · doi:10.1016/j.thromres.2018.06.020 · Cited by 37 · see citing works

The Many Faces of Cytokine Release Syndrome-Related Coagulopathy

Wang, J., & Doran, J. (2021) · Clinical Hematology International · doi:10.2991/chi.k.210117.001 · Cited by 39 · see citing works

Pyroptotic cell death in SARS-CoV-2 infection: revealing its roles during the immunopathogenesis of COVID-19

Wang, M., Chang, W., Zhang, L., & Zhang, Y. (2022) · International Journal of Biological Sciences · doi:10.7150/ijbs.77561 · Cited by 34 · see citing works

Manifestations of blood coagulation and its relation to clinical outcomes in severe COVID‐19 patients: Retrospective analysis

Zhang, Y., He, L., Chen, H., Lu, S., Xiong, Y.-F., Liu, J., Zheng, Y., Wang, S. L., & Liu, L. (2020) · International Journal of Laboratory Hematology · doi:10.1111/ijlh.13273 · Cited by 36 · see citing works

Interplay between acute phase response and coagulation/fibrinolysis in chronic spontaneous urticaria

Grzanka, R., Damasiewicz-Bodzek, A., & Kasperska−Zając, A. (2018) · Allergy Asthma and Clinical Immunology · doi:10.1186/s13223-018-0255-8 · Cited by 34 · see citing works

Investigation for role of tissue factor and blood coagulation system in severe acute pancreatitis and associated liver injury

Ou, Z.-B., Miao, C., Ye, M.-X., Xing, D.-P., He, K., Li, P., Zhu, R., & Gong, J. (2016) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.11.039 · Cited by 33 · see citing works

Elevated levels of damage-associated molecular patterns HMGB1 and S100A8/A9 coupled with toll-like receptor-triggered monocyte activation are associated with inflammation in patients with myelofibrosis

Luca, G. D., Goette, N. P., Lev, P. R., Pietto, M. C. B., Oyarzún, C. P. M., Ríos, M. A. C., Moiraghi, B., Sackmann, F., Kamiya, L. J., Verri, V., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1365015 · Cited by 32 · see citing works

Immunothrombosis and the molecular control of tissue factor by pyroptosis: prospects for new anticoagulants

Ryan, T. A. J., Preston, R. J. S., & O'Neill, L. A. J. (2022) · Biochemical Journal · doi:10.1042/bcj20210522 · Cited by 32 · see citing works

Do methodological differences account for the current controversy on tissue factor expression in platelets?

Brambilla, M., Rossetti, L., Zara, C., Canzano, P., Giesen, P. L. A., Tremoli, E., & Camera, M. (2017) · Platelets · doi:10.1080/09537104.2017.1327653 · Cited by 32 · see citing works

MicroRNA-19a contributes to the epigenetic regulation of tissue factor in diabetes

Witkowski, M., Tabaraie, T., Steffens, D., Friebel, J., Dörner, A., Skurk, C., Witkowski, M., Stratmann, B., Tschoepe, D., Landmesser, U., et al. (2018) · Cardiovascular Diabetology · doi:10.1186/s12933-018-0678-z · Cited by 31 · see citing works

HIV-Related Myocardial Fibrosis: Inflammatory Hypothesis and Crucial Role of Immune Cells Dysregulation

Teer, E., Dominick, L., Mukonowenzou, N. C., & Essop, M. F. (2022) · Cells · doi:10.3390/cells11182825 · Cited by 30 · see citing works

Characterization of Dermal Stem Cells of Diabetic Patients

Ferroni, L., Gardin, C., Paola, L. D., Campo, G. C., Cimaglia, P., Bellin, G., Pinton, P., & Zavan, B. (2019) · Cells · doi:10.3390/cells8070729 · Cited by 30 · see citing works

Interactions of mesenchymal stromal/stem cells and immune cells following MSC-based therapeutic approaches in rheumatoid arthritis

Dehnavi, S., Sadeghi, M., Afshari, J. T., & Mohammadi, M. (2023) · Cellular Immunology · doi:10.1016/j.cellimm.2023.104771 · Cited by 30 · see citing works

Good Fences Make Good Neighbors: Human Immunodeficiency Virus and Vascular Disease

Mayne, E. S., & Louw, S. J. (2019) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofz303 · Cited by 29 · see citing works

Inflammation and coagulation crosstalk induced by BJcuL, a galactose-binding lectin isolated from Bothrops jararacussu snake venom

Cezarette, G. N., Sartim, M. A., & Sampaio, S. V. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.12.015 · Cited by 29 · see citing works

The gut–heart axis: a review of gut microbiota, dysbiosis, and cardiovascular disease development

Abdulrahim, A. O., Doddapaneni, N. S. P., Salman, N., Giridharan, A., Thomas, J., Sharma, K., Abboud, E., Rochill, K., Shreelakshmi, B., Gupta, V., et al. (2024) · Annals of Medicine and Surgery · doi:10.1097/ms9.0000000000002789 · Cited by 31 · see citing works

A Novel Volume-Stable Collagen Matrix Induces Changes in the Behavior of Primary Human Oral Fibroblasts, Periodontal Ligament, and Endothelial Cells

Asparuhova, M. B., Stähli, A., Guldener, K., & Sculean, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22084051 · Cited by 28 · see citing works

Tissue Factor, Thrombosis, and Chronic Kidney Disease

Oe, Y., & Takahashi, N. (2022) · Biomedicines · doi:10.3390/biomedicines10112737 · Cited by 30 · see citing works

Sex, Endothelial Cell Functions, and Peripheral Artery Disease

Cartland, S. P., Stanley, C. P., Bursill, C. A., Passam, F. H., Figtree, G. A., Patel, S., Loa, J., Golledge, J., Robinson, D. A., Aitken, S., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242417439 · Cited by 27 · see citing works

Neurobiology of Schizophrenia (to the Construction of Clinical and Biological Model)

Klyushnik, T. P., Ab, S., Zozulya, S. A., & Voronova, E. I. (2021) · Psikhiatriya · doi:10.30629/2618-6667-2021-19-1-6-15 · Cited by 27 · see citing works

Protective effect of pterostilbene on concanavalin A-induced acute liver injury

Wu, J., Li, M., He, J., Lv, K., Wang, M., Guan, W., Liu, J., Tao, Y., Li, S., Ho, C.-T., et al. (2019) · Food & Function · doi:10.1039/c9fo01405e · Cited by 27 · see citing works

Extracellular vesicles in toxicological studies: key roles in communication between environmental stress and adverse outcomes

Qin, Y., Li, L., & Huang, Q. (2020) · Journal of Applied Toxicology · doi:10.1002/jat.3963 · Cited by 26 · see citing works

Disseminated intravascular coagulation: cause, molecular mechanism, diagnosis, and therapy

Gong, F., Zheng, X., Zhao, S., Liu, H., Chen, E., Xie, R., Li, R., & Chen, Y. (2025) · MedComm · doi:10.1002/mco2.70058 · Cited by 25 · see citing works

Hemokinin-1 Gene Expression Is Upregulated in Trigeminal Ganglia in an Inflammatory Orofacial Pain Model: Potential Role in Peripheral Sensitization

Aczél, T., Kecskés, A., Kun, J., Szenthe, K., Bánáti, F., Szathmáry, S., Herczeg, R., Urban, P. P., Gyenesei, A., Gaszner, B., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21082938 · Cited by 25 · see citing works

Role of pyroptosis in hemostasis activation in sepsis

Zhu, C., Liang, Y., Luo, Y., & Ma, X. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1114917 · Cited by 25 · see citing works

The Role of Tissue Factor In Signaling Pathways of Pathological Conditions and Angiogenesis

Heidari, Z., Naeimzadeh, Y., Fallahi, J., Savardashtaki, A., Razban, V., & Khajeh, S. (2023) · Current Molecular Medicine · doi:10.2174/0115665240258746230919165935 · Cited by 26 · see citing works

Metformin Is Associated with Reduced Tissue Factor Procoagulant Activity in Patients with Poorly Controlled Diabetes

Witkowski, M., Friebel, J., Tabaraie, T., Grabitz, S., Dörner, A., Taghipour, L., Jakobs, K., Stratmann, B., Tschoepe, D., Landmesser, U., et al. (2020) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-020-07040-7 · Cited by 24 · see citing works

Pleiotropic Effects of PCSK9: Focus on Thrombosis and Haemostasis

Puccini, M., Landmesser, U., & Rauch, U. (2022) · Metabolites · doi:10.3390/metabo12030226 · Cited by 24 · see citing works

Pretreatment with Eupatilin Attenuates Inflammation and Coagulation in Sepsis by Suppressing JAK2/STAT3 Signaling Pathway

Lu, Y., Li, D., Huang, Y., Sun, Y., Zhou, H., Ye, F., Yang, H., Xu, T., Quan, S., & Pan, J. (2023) · Journal of Inflammation Research · doi:10.2147/jir.s393850 · Cited by 24 · see citing works

An autophagic deficit in the uterine vessel microenvironment provokes hyperpermeability through deregulated VEGFA, NOS1, and CTNNB1

Lee, B., Shin, H., Oh, J., Park, J., Park, M., Yang, S. C., Jun, J. H., Hong, S., Song, H., & Lim, H. J. (2020) · Autophagy · doi:10.1080/15548627.2020.1778292 · Cited by 24 · see citing works

Thrombin Aptamer-Modified Metal–Organic Framework Nanoparticles: Functional Nanostructures for Sensing Thrombin and the Triggered Controlled Release of Anti-Blood Clotting Drugs

Chen, W., Karmi, O., Willner, B., Nechushtai, R., & Willner, I. (2019) · Sensors · doi:10.3390/s19235260 · Cited by 23 · see citing works

Coagulation, Protease-Activated Receptors, and Diabetic Kidney Disease: Lessons from eNOS-Deficient Mice

Oe, Y., Miyazaki, M., & Takahashi, N. (2021) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.255.1 · Cited by 23 · see citing works

Recurrent Pulmonary Embolism and Hypersensitivity Pneumonitis Secondary to Aspergillus, in a Compost Plant Worker: Case Report and Review of Literature

Lal, A., Akhtar, J., Pinto, S., Grewal, H., & Martin, K. B. (2018) · Lung · doi:10.1007/s00408-018-0142-6 · Cited by 22 · see citing works

Venous thromboembolism in head and neck cancer surgery

Ahmad, F. I., & Clayburgh, D. R. (2016) · Cancers of the Head & Neck · doi:10.1186/s41199-016-0014-9 · Cited by 22 · see citing works

EGFR is a pivotal regulator of thrombin-mediated inflammation in primary human nucleus pulposus culture

Huang, B., Chen, T.-S., BAU, D.-T., Chuang, I.-C., Tsai, C., Chang, P.-C., & Lu, D. (2017) · Scientific Reports · doi:10.1038/s41598-017-09122-3 · Cited by 22 · see citing works

Procoagulant Properties of Mesenchymal Stem Cells and Extracellular Vesicles: A Novel Aspect of Thrombosis Pathogenesis

Yang, B., Long, Y.-Y., Zhang, A., Wang, H., Chen, Z., & Li, Q. (2023) · Stem Cells · doi:10.1093/stmcls/sxad087 · Cited by 22 · see citing works

Discovery of anti-stroke active substances in Guhong injection based on multi-phenotypic screening of zebrafish

Wang, Y., Wu, H., Sheng, H., Wang, Y., Li, X., Wáng, Y., & Zhao, L. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113744 · Cited by 21 · see citing works

Mesenchymal Stem Cells and Their Extracellular Vesicles: A Potential Game Changer for the COVID-19 Crisis

Kassem, D. H., & Kamal, M. M. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.587866 · Cited by 21 · see citing works

Gab2 (Grb2-Associated Binder2) Plays a Crucial Role in Inflammatory Signaling and Endothelial Dysfunction

Kondreddy, V. K. R., Magisetty, J., Keshava, S., Rao, L. V. M., & Pendurthi, U. R. (2021) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.121.316153 · Cited by 22 · see citing works

Inhibition of the extrinsic or intrinsic coagulation pathway during pneumonia-derived sepsis

Stroo, I., Ding, C., Novak, A., Yang, J., Roelofs, J. J. T. H., Meijers, J. C. M., Revenko, A. S., Veer, C. V. ′., Zeerleder, S. S., Crosby, J. R., et al. (2018) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00014.2018 · Cited by 20 · see citing works

Role of Mesenchymal Stem/Stromal Cells in Coagulation

Guillamat‐Prats, R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231810393 · Cited by 23 · see citing works

Intestinal Barrier Dysfunction and Microbial Translocation in Patients with First-Diagnosed Atrial Fibrillation

Blöbaum, L., Witkowski, M., Wegner, M., Lammel, S., Schencke, P.-A., Jakobs, K., Puccini, M., Reißner, D., Steffens, D., Landmesser, U., et al. (2023) · Biomedicines · doi:10.3390/biomedicines11010176 · Cited by 20 · see citing works

Inflammation-Induced Coagulopathy Substantially Differs Between COVID-19 and Septic Shock: A Prospective Observational Study

Dechamps, M., Poortere, J. D., Martin, M., Gatto, L., Daumerie, A., Bouzin, C., Octave, M., Ginion, A., Robaux, V., Pirotton, L., et al. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2021.780750 · Cited by 20 · see citing works

Gut microbiota-derived metabolites: Potential targets for cardiorenal syndrome

Lai, Y.-C., Zhu, Y., Zhang, X., Ding, S., Wang, F., Hao, J., Wang, Z., Shi, C., Xu, Y., Zheng, L., et al. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107672 · Cited by 21 · see citing works

Therapeutic Strategies Focused on Cancer-Associated Hypercoagulation for Ovarian Clear Cell Carcinoma

Tamura, R., Yoshihara, K., & Enomoto, T. (2022) · Cancers · doi:10.3390/cancers14092125 · Cited by 21 · see citing works

Plasminogen Activator Inhibitor-1 Potentiates Neutrophil Infiltration and Tissue Injury in Colitis

Wang, X., Li, G., Huang, J., Jiang, S., Li, N., Mu, H., & Xu, C. (2023) · International Journal of Biological Sciences · doi:10.7150/ijbs.75890 · Cited by 18 · see citing works

Disseminated intravascular coagulation caused by moojenactivase, a procoagulant snake venom metalloprotease

Sartim, M. A., Cezarette, G. N., Jacob‐Ferreira, A. L., Frantz, F. G., Faccioli, L. H., & Sampaio, S. V. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.05.146 · Cited by 18 · see citing works

Post-transcriptional control of haemostatic genes: mechanisms and emerging therapeutic concepts in thrombo-inflammatory disorders

Danckwardt, S., Trégouët, D., & Castoldi, E. (2023) · Cardiovascular Research · doi:10.1093/cvr/cvad046 · Cited by 17 · see citing works

Research progress in clinical trials of stem cell therapy for stroke and neurodegenerative diseases

Yan, S., de Souza, S. C., Xie, Z., & Bao, Y.-X. (2023) · Ibrain · doi:10.1002/ibra.12095 · Cited by 15 · see citing works

Assessment of the Procoagulant Activity of Microparticles and the Protein Z System in Patients Undergoing Off-Pump Coronary Artery Bypass Surgery

Słomka, A., Piekuś, A., Kowalewski, M., Pawliszak, W., Anisimowicz, L., & Żekanowska, E. (2017) · Angiology · doi:10.1177/0003319717706616 · Cited by 16 · see citing works

Editorial Commentary: Tissue factor expression by the endothelium: Coagulation or inflammation?

Antoniak, S., & Mackman, N. (2016) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2015.12.002 · Cited by 16 · see citing works

Association of coagulation disturbances with severity of COVID-19: a longitudinal study

Lu, H., Chen, M., Tang, S., & Yu, W. (2021) · Hematology · doi:10.1080/16078454.2021.1968648 · Cited by 15 · see citing works

Formation and elimination of soluble fibrin and D-dimer in the bloodstream

Udovenko, A. V., Em, M., Korolova, D., Druzhyna, N., Chernyshenko, V. O., & Комісаренко, С. В. (2023) · Croatian Medical Journal · doi:10.3325/cmj.2023.64.421 · Cited by 15 · see citing works

Coagulation abnormalities associated with CAR ‐T‐cell therapy in haematological malignancies: A review

Peng, X., Zhang, X., Zhao, M., Chang, D., Yang, L., Mei, H., & Zhang, R. (2024) · British Journal of Haematology · doi:10.1111/bjh.19583 · Cited by 15 · see citing works

Tissue factor in infection and severe inflammation

Levi, M., van der Poll, T., & ten Cate, H. (2006) · Seminars in Thrombosis and Hemostasis · doi:10.1055/s-2006-933338 · Cited by 126 · see citing works

Editorial Commentary: Tissue factor expression by the endothelium: Coagulation or inflammation?

Antoniak, S., & MacKman, N. (2020) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/900p-gg48

Tissue factor mediates inflammation

Chu, A. J. (2005) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2005.06.005 · Cited by 156 · see citing works

Tissue Factor: A Critical Role in Inflammation and Cancer

Lwaleed, B. A., Cooper, A. J., Voegeli, D., & Getliffe, K. (2007) · Biological Research For Nursing · doi:10.1177/1099800407305733 · Cited by 30 · see citing works

The many faces of tissue factor

Mackman, N. (2009) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2009.03368.x · Cited by 177 · see citing works