Tissue factor as a link between inflammation and coagulation

Rivaroxaban in Patients with a Recent Acute Coronary Syndrome

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Tissue Factor

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Intravascular Mesenchymal Stromal/Stem Cell Therapy Product Diversification: Time for New Clinical Guidelines

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Risk Factors Associated With Clinical Outcomes in 323 Coronavirus Disease 2019 (COVID-19) Hospitalized Patients in Wuhan, China

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The Therapeutic Potential of Mesenchymal Stromal Cells for Regenerative Medicine: Current Knowledge and Future Understandings

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Improved MSC Minimal Criteria to Maximize Patient Safety: A Call to Embrace Tissue Factor and Hemocompatibility Assessment of MSC Products

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Macrophage activation syndrome and COVID-19

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Reactions Related to CAR-T Cell Therapy

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Microvascular thrombosis: experimental and clinical implications

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Beyond thrombosis: the impact of tissue factor signaling in cancer

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Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis

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Endothelial cells: source, barrier, and target of defensive mediators

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Hypercoagulopathy and Adipose Tissue Exacerbated Inflammation May Explain Higher Mortality in COVID-19 Patients With Obesity

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Intravenous Infusion of Human Adipose Mesenchymal Stem Cells Modifies the Host Response to Lipopolysaccharide in Humans: A Randomized, Single-Blind, Parallel Group, Placebo Controlled Trial

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From Infection to Death: An Overview of the Pathogenesis of Visceral Leishmaniasis

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Micro–RNA-126 Reduces the Blood Thrombogenicity in Diabetes Mellitus via Targeting of Tissue Factor

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The interplay between hemostasis and immune response in biomaterial development for osteogenesis

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The molecular basis for the prothrombotic state in sickle cell disease

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Balancing Microthrombosis and Inflammation via Injectable Protein Hydrogel for Inflammatory Bowel Disease

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Thrombin, a Mediator of Coagulation, Inflammation, and Neurotoxicity at the Neurovascular Interface: Implications for Alzheimer’s Disease

Iannucci, J., Renehan, W. E., & Grammas, P. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00762 · Cited by 75

Molecular Insights Into SARS COV-2 Interaction With Cardiovascular Disease: Role of RAAS and MAPK Signaling

Wehbe, Z., Hammoud, S. H., Soudani, N., Zaraket, H., EL‐Yazbi, A. F., & Eid, A. H. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00836 · Cited by 71

Coagulopathy and thromboembolic events in patients with SARS-CoV-2 infection: pathogenesis and management strategies

Allegra, A., Innao, V., Allegra, A. G., & Musolino, C. (2020) · Annals of Hematology · doi:10.1007/s00277-020-04182-4 · Cited by 66

COVID-19 and coagulative axis: review of emerging aspects in a novel disease

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Mesenchymal stem cell immunomodulation: in pursuit of controlling COVID-19 related cytokine storm

Song, N., Wakimoto, H., Rossignoli, F., Bhere, D., Ciccocioppo, R., Chen, K.-S., Khalsa, J. K., Mastrolia, I., Samarelli, A. V., Dominici, M., et al. (2021) · Stem Cells · doi:10.1002/stem.3354 · Cited by 62

[Characteristics, causes, diagnosis and treatment of coagulation dysfunction in patients with COVID-19].

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Extracellular vesicles released in response to respiratory exposures: implications for chronic disease

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Thrombotic manifestations of VEXAS syndrome

Groarke, E. M., Dulau‐Florea, A., & Kanthi, Y. M. (2021) · Seminars in Hematology · doi:10.1053/j.seminhematol.2021.10.006 · Cited by 55

PCSK9 Induces Tissue Factor Expression by Activation of TLR4/NFkB Signaling

Scalise, V., Sanguinetti, C., Neri, T., Cianchetti, S., Lai, M., Carnicelli, V., Celi, A., & Pedrinelli, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222312640 · Cited by 58

The SIRT1 inhibitor EX-527 suppresses mTOR activation and alleviates acute lung injury in mice with endotoxiemia

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A new perspective on cerebrospinal fluid dynamics after subarachnoid hemorrhage: From normal physiology to pathophysiological changes

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The intersection of coagulation activation and inflammation after injury: What you need to know

Costantini, T. W., Kornblith, L. Z., Pritts, T. A., & Coimbra, R. S. M. (2023) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0000000000004190 · Cited by 52

Protease-Activated Receptor PAR-4: An Inducible Switch between Thrombosis and Vascular Inflammation?

Fender, A. C., Rauch, B. H., Geisler, T., & Schrör, K. (2017) · Thrombosis and Haemostasis · doi:10.1160/th17-03-0219 · Cited by 50

Vascular miR-181b controls tissue factor-dependent thrombogenicity and inflammation in type 2 diabetes

Witkowski, M., Witkowski, M., Saffarzadeh, M., Friebel, J., Tabaraie, T., Ta Bao, L., Chakraborty, A., Dörner, A., Stratmann, B., Tschoepe, D., et al. (2020) · Cardiovascular Diabetology · doi:10.1186/s12933-020-0993-z · Cited by 50

HIV-related cardiovascular diseases: the search for a unifying hypothesis

Dominick, L., Midgley, N., Swart, L.-M., Sprake, D., Deshpande, G., Laher, I., Joseph, D. E., Teer, E., & Essop, M. F. (2020) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00549.2019 · Cited by 51

Mesenchymal stem cells biological and biotechnological advances: Implications for clinical applications

Pharoun, J., Berro, J., Sobh, J., Abou-Younes, M.-M., Nasr, L., Majed, A., Khalil, A., Joseph, J., Stephan, & Faour, W. H. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176719 · Cited by 55

Proteomic analysis reveals procoagulant properties of cigarette smoke‐induced extracellular vesicles

Benedikter, B. J., Bouwman, F. G., Heinzmann, A. C. A., Vajen, T., Mariman, E. C. M., Wouters, E. F. �., Savelkoul, P. H. M., Koenen, R. R., Rohde, G. G. U., van Oerle, R., et al. (2019) · Journal of Extracellular Vesicles · doi:10.1080/20013078.2019.1585163 · Cited by 47

COVID‐19‐related coagulopathy: A review of pathophysiology and pharmaceutical management

Vajari, M. K., Shirin, M., Pourbagheri‐Sigaroodi, A., Akbari, M. E., Abolghasemi, H., & Bashash, D. (2021) · Cell Biology International · doi:10.1002/cbin.11623 · Cited by 48

Coagulation cascade and complement system in systemic lupus erythematosus

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Sickle Cell Disease: A Paradigm for Venous Thrombosis Pathophysiology

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Post-stroke Impairment of the Blood–Brain Barrier and Perifocal Vasogenic Edema Is Alleviated by Endovascular Mesenchymal Stem Cell Administration: Modulation of the PKCδ/MMP9/AQP4-Mediated Pathway

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Mechanisms and interactions in concomitant use of herbs and warfarin therapy: An updated review

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When Origin Matters: Properties of Mesenchymal Stromal Cells From Different Sources for Clinical Translation in Kidney Disease

Calcat-i-Cervera, S., Sanz‐Nogués, C., & O’Brien, T. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.728496 · Cited by 42

NLRP3 inflammasome contributes to endotoxin-induced coagulation

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Thrombin, a Key Driver of Pathological Inflammation in the Brain

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Withametelin: a biologically active withanolide in cancer, inflammation, pain and depression

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ICAM-1–targeted thrombomodulin mitigates tissue factor–driven inflammatory thrombosis in a human endothelialized microfluidic model

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Tissue factor (:Factor VIIa) in the heart and vasculature: More than an envelope

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The Many Faces of Cytokine Release Syndrome-Related Coagulopathy

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Pyroptotic cell death in SARS-CoV-2 infection: revealing its roles during the immunopathogenesis of COVID-19

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Manifestations of blood coagulation and its relation to clinical outcomes in severe COVID‐19 patients: Retrospective analysis

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Interplay between acute phase response and coagulation/fibrinolysis in chronic spontaneous urticaria

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Investigation for role of tissue factor and blood coagulation system in severe acute pancreatitis and associated liver injury

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Elevated levels of damage-associated molecular patterns HMGB1 and S100A8/A9 coupled with toll-like receptor-triggered monocyte activation are associated with inflammation in patients with myelofibrosis

Luca, G. D., Goette, N. P., Lev, P. R., Pietto, M. C. B., Oyarzún, C. P. M., Ríos, M. A. C., Moiraghi, B., Sackmann, F., Kamiya, L. J., Verri, V., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1365015 · Cited by 32

Immunothrombosis and the molecular control of tissue factor by pyroptosis: prospects for new anticoagulants

Ryan, T. A. J., Preston, R. J. S., & O'Neill, L. A. J. (2022) · Biochemical Journal · doi:10.1042/bcj20210522 · Cited by 35

Do methodological differences account for the current controversy on tissue factor expression in platelets?

Brambilla, M., Rossetti, L., Zara, C., Canzano, P., Giesen, P. L. A., Tremoli, E., & Camera, M. (2017) · Platelets · doi:10.1080/09537104.2017.1327653 · Cited by 32

MicroRNA-19a contributes to the epigenetic regulation of tissue factor in diabetes

Witkowski, M., Tabaraie, T., Steffens, D., Friebel, J., Dörner, A., Skurk, C., Witkowski, M., Stratmann, B., Tschoepe, D., Landmesser, U., et al. (2018) · Cardiovascular Diabetology · doi:10.1186/s12933-018-0678-z · Cited by 31

HIV-Related Myocardial Fibrosis: Inflammatory Hypothesis and Crucial Role of Immune Cells Dysregulation

Teer, E., Dominick, L., Mukonowenzou, N. C., & Essop, M. F. (2022) · Cells · doi:10.3390/cells11182825 · Cited by 30

Characterization of Dermal Stem Cells of Diabetic Patients

Ferroni, L., Gardin, C., Paola, L. D., Campo, G. C., Cimaglia, P., Bellin, G., Pinton, P., & Zavan, B. (2019) · Cells · doi:10.3390/cells8070729 · Cited by 30

Interactions of mesenchymal stromal/stem cells and immune cells following MSC-based therapeutic approaches in rheumatoid arthritis

Dehnavi, S., Sadeghi, M., Afshari, J. T., & Mohammadi, M. (2023) · Cellular Immunology · doi:10.1016/j.cellimm.2023.104771 · Cited by 30

Good Fences Make Good Neighbors: Human Immunodeficiency Virus and Vascular Disease

Mayne, E. S., & Louw, S. J. (2019) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofz303 · Cited by 29

Inflammation and coagulation crosstalk induced by BJcuL, a galactose-binding lectin isolated from Bothrops jararacussu snake venom

Cezarette, G. N., Sartim, M. A., & Sampaio, S. V. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.12.015 · Cited by 29

The gut–heart axis: a review of gut microbiota, dysbiosis, and cardiovascular disease development

Abdulrahim, A. O., Doddapaneni, N. S. P., Salman, N., Giridharan, A., Thomas, J., Sharma, K., Abboud, E., Rochill, K., Shreelakshmi, B., Gupta, V., et al. (2024) · Annals of Medicine and Surgery · doi:10.1097/ms9.0000000000002789 · Cited by 33

A Novel Volume-Stable Collagen Matrix Induces Changes in the Behavior of Primary Human Oral Fibroblasts, Periodontal Ligament, and Endothelial Cells

Asparuhova, M. B., Stähli, A., Guldener, K., & Sculean, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22084051 · Cited by 28

Tissue Factor, Thrombosis, and Chronic Kidney Disease

Oe, Y., & Takahashi, N. (2022) · Biomedicines · doi:10.3390/biomedicines10112737 · Cited by 30

Sex, Endothelial Cell Functions, and Peripheral Artery Disease

Cartland, S. P., Stanley, C. P., Bursill, C. A., Passam, F. H., Figtree, G. A., Patel, S., Loa, J., Golledge, J., Robinson, D. A., Aitken, S., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242417439 · Cited by 30

Neurobiology of Schizophrenia (to the Construction of Clinical and Biological Model)

Klyushnik, T. P., Ab, S., Zozulya, S. A., & Voronova, E. I. (2021) · Psikhiatriya · doi:10.30629/2618-6667-2021-19-1-6-15 · Cited by 27

Protective effect of pterostilbene on concanavalin A-induced acute liver injury

Wu, J., Li, M., He, J., Lv, K., Wang, M., Guan, W., Liu, J., Tao, Y., Li, S., Ho, C.-T., et al. (2019) · Food & Function · doi:10.1039/c9fo01405e · Cited by 27

Extracellular vesicles in toxicological studies: key roles in communication between environmental stress and adverse outcomes

Qin, Y., Li, L., & Huang, Q. (2020) · Journal of Applied Toxicology · doi:10.1002/jat.3963 · Cited by 26

Disseminated intravascular coagulation: cause, molecular mechanism, diagnosis, and therapy

Gong, F., Zheng, X., Zhao, S., Liu, H., Chen, E., Xie, R., Li, R., & Chen, Y. (2025) · MedComm · doi:10.1002/mco2.70058 · Cited by 32

Hemokinin-1 Gene Expression Is Upregulated in Trigeminal Ganglia in an Inflammatory Orofacial Pain Model: Potential Role in Peripheral Sensitization

Aczél, T., Kecskés, A., Kun, J., Szenthe, K., Bánáti, F., Szathmáry, S., Herczeg, R., Urban, P. P., Gyenesei, A., Gaszner, B., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21082938 · Cited by 25

Role of pyroptosis in hemostasis activation in sepsis

Zhu, C., Liang, Y., Luo, Y., & Ma, X. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1114917 · Cited by 25

The Role of Tissue Factor In Signaling Pathways of Pathological Conditions and Angiogenesis

Heidari, Z., Naeimzadeh, Y., Fallahi, J., Savardashtaki, A., Razban, V., & Khajeh, S. (2023) · Current Molecular Medicine · doi:10.2174/0115665240258746230919165935 · Cited by 26

Metformin Is Associated with Reduced Tissue Factor Procoagulant Activity in Patients with Poorly Controlled Diabetes

Witkowski, M., Friebel, J., Tabaraie, T., Grabitz, S., Dörner, A., Taghipour, L., Jakobs, K., Stratmann, B., Tschoepe, D., Landmesser, U., et al. (2020) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-020-07040-7 · Cited by 26

Pleiotropic Effects of PCSK9: Focus on Thrombosis and Haemostasis

Puccini, M., Landmesser, U., & Rauch, U. (2022) · Metabolites · doi:10.3390/metabo12030226 · Cited by 26

Pretreatment with Eupatilin Attenuates Inflammation and Coagulation in Sepsis by Suppressing JAK2/STAT3 Signaling Pathway

Lu, Y., Li, D., Huang, Y., Sun, Y., Zhou, H., Ye, F., Yang, H., Xu, T., Quan, S., & Pan, J. (2023) · Journal of Inflammation Research · doi:10.2147/jir.s393850 · Cited by 24

An autophagic deficit in the uterine vessel microenvironment provokes hyperpermeability through deregulated VEGFA, NOS1, and CTNNB1

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Thrombin Aptamer-Modified Metal–Organic Framework Nanoparticles: Functional Nanostructures for Sensing Thrombin and the Triggered Controlled Release of Anti-Blood Clotting Drugs

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Coagulation, Protease-Activated Receptors, and Diabetic Kidney Disease: Lessons from eNOS-Deficient Mice

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