The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.
Prostaglandins in bone: bad cop, good cop?
Open accessAbstract
Prostaglandins (PGs) are multifunctional regulators of bone metabolism that stimulate both bone resorption and formation. PGs have been implicated in bone resorption associated with inflammation and metastatic bone disease and also in bone formation associated with fracture healing and heterotopic ossification. Recent studies identified roles for inducible cyclooxygenase-2 (COX-2) and PGE2 receptors in these processes. Although the effects of PGs have been most often associated with cAMP production and PKA activation, PGs can engage an extensive G-protein signaling network. Further analysis of COX-2 and PG receptors and their downstream G-protein signaling in bone could provide us with important clues to the regulation of skeletal cell growth in both health and disease.
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Cites
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Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis
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Self-citationCyclooxygenases: structural and functional insights
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The Osteocyte: An Endocrine Cell … and More
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Mechanisms of the Anti-Cancer and Anti-Inflammatory Actions of Vitamin D
Krishnan, A. V., & Feldman, D. (2011) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-010510-100611 · Cited by 470
Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis
Chen, H., Hu, B., Lv, X., Zhu, S., Zhen, G., Wan, M., Jain, A., Gao, B., Chai, Y., Yang, M., et al. (2019) · Nature Communications · doi:10.1038/s41467-018-08097-7 · Cited by 321
The Prostanoid EP4 Receptor and Its Signaling Pathway
Yokoyama, U., Iwatsubo, K., Umemura, M., Fujita, T., & Ishikawa, Y. (2013) · Pharmacological Reviews · doi:10.1124/pr.112.007195 · Cited by 264
Oxylipin-PPARγ-initiated adipocyte senescence propagates secondary senescence in the bone marrow
Liu, X., Gu, Y., Kumar, S., Amin, S., Guo, Q., Wang, J., Fang, C.-L., Cao, X., & Wan, M. (2023) · Cell Metabolism · doi:10.1016/j.cmet.2023.03.005 · Cited by 137
Metadata
- Authors
- Blackwell, K. A., Raisz, L. G., & Pilbeam, C. C.
- Venue
- Trends in Endocrinology & Metabolism
- Publisher
- Elsevier BV
- Published
- 2010-05
- Volume
- 21
- Issue
- 5
- Pages
- 294-301
- ISSN
- 1043-2760 (ISSN-L)
- OpenAlex
- W2024135486
- Cited by
- 311
- References
- 72
- FWCI
- 1.22
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
