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Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis

North, Trista E., Goessling, Wolfram, Walkley, Carl R., Lengerke, Claudia, Kopani, Kamden R., Lord, Allegra M., Weber, Gerhard J., Bowman, Teresa V., Jang, Il-Ho, Grosser, Tilo, FitzGerald, Garret A., Daley, George Q., Orkin, Stuart H., Zon, Leonard I.·2007·Nature

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Research works printed but not linked: 29

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  2. Galloway, J. L. & Zon, L. I. Ontogeny of hematopoiesis: examining the emergence of hematopoietic cells in the vertebrate embryo. Curr. Top. Dev. Biol. 53, 139–158 (2003) · DOI
  3. North, T. E. et al. Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo. Immunity 16, 661–672 (2002) · DOI
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  5. Kalev-Zylinska, M. L. et al. Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1–CBF2T1 transgene advances a model for studies of leukemogenesis. Development 129, 2015–2030 (2002) · DOI
  6. Grosser, T., Yusuff, S., Cheskis, E., Pack, M. A. & FitzGerald, G. A. Developmental expression of functional cyclooxygenases in zebrafish. Proc. Natl Acad. Sci. USA 99, 8418–8423 (2002) · DOI
  7. Cha, Y. I., Kim, S. H., Solnica-Krezel, L. & Dubois, R. N. Cyclooxygenase-1 signaling is required for vascular tube formation during development. Dev. Biol. 282, 274–283 (2005) · DOI
  8. Cha, Y. I. et al. Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation. Genes Dev. 20, 77–86 (2006) · DOI
  9. Burns, C. E., Traver, D., Mayhall, E., Shepard, J. L. & Zon, L. I. Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev. 19, 2331–2342 (2005) · DOI · Paper page
  10. Nakano, T., Kodama, H. & Honjo, T. In vitro development of primitive and definitive erythrocytes from different precursors. Science 272, 722–724 (1996) · DOI
  11. Ivanova, N. B. et al. A stem cell molecular signature. Science 298, 601–604 (2002) · DOI
  12. Akashi, K. et al. Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis. Blood 101, 383–389 (2003) · DOI
  13. Venezia, T. A. et al. Molecular signatures of proliferation and quiescence in hematopoietic stem cells. PLoS Biol. 2, e301 (2004) · DOI
  14. Zhang, C. C. & Lodish, H. F. Insulin-like growth factor 2 expressed in a novel fetal liver cell population is a growth factor for hematopoietic stem cells. Blood 103, 2513–2521 (2004) · DOI
  15. Boer, A. K., Drayer, A. L., Rui, H. & Vellenga, E. Prostaglandin-E2 enhances EPO-mediated STAT5 transcriptional activity by serine phosphorylation of CREB. Blood 100, 467–473 (2002) · DOI
  16. Rocca, B. et al. Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed platelets. Proc. Natl Acad. Sci. USA 99, 7634–7639 (2002) · DOI
  17. Feher, I. & Gidali, J. Prostaglandin E2 as stimulator of haemopoietic stem cell proliferation. Nature 247, 550–551 (1974) · DOI
  18. Langenbach, R. et al. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell 83, 483–492 (1995) · DOI
  19. Lorenz, M. et al. Cyclooxygenase-2 is essential for normal recovery from 5-fluorouracil-induced myelotoxicity in mice. Exp. Hematol. 27, 1494–1502 (1999) · DOI
  20. Cayeux, S. J., Beverley, P. C., Schulz, R. & Dorken, B. Elevated plasma prostaglandin E2 levels found in 14 patients undergoing autologous bone marrow or stem cell transplantation. Bone Marrow Transplant. 12, 603–608 (1993)
  21. Talosi, G. et al. Prostaglandin E1 treatment in patent ductus arteriosus dependent congenital heart defects. J. Perinat. Med. 32, 368–374 (2004) · DOI
  22. Thanopoulos, B. D., Andreou, A. & Frimas, C. Prostaglandin E2 administration in infants with ductus-dependent cyanotic congenital heart disease. Eur. J. Pediatr. 146, 279–282 (1987) · DOI
  23. Hertelendy, F., Woods, R. & Jaffe, B. M. Prostaglandin E levels in peripheral blood during labor. Prostaglandins 3, 223–227 (1973) · DOI
  24. Zhu, H. et al. Regulation of the lmo2 promoter during hematopoietic and vascular development in zebrafish. Dev. Biol. 281, 256–269 (2005) · DOI
  25. Weber, G. J. et al. Mutant-specific gene programs in the zebrafish. Blood 106, 521–530 (2005) · DOI
  26. Pini, B. et al. Prostaglandin E synthases in zebrafish. Arterioscler. Thromb. Vasc. Biol. 25, 315–320 (2005) · DOI
  27. Traver, D. et al. Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation. Blood 104, 1298–1305 (2004) · DOI
  28. Kyba, M. et al. Enhanced hematopoietic differentiation of embryonic stem cells conditionally expressing Stat5. Proc. Natl Acad. Sci. USA 100 (Suppl 1). 11904–11910 (2003) · DOI
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Metadata

Authors
North, T. E., Goessling, W., Walkley, C. R., Lengerke, C., Kopani, K. R., Lord, A. M., Weber, G. J., Bowman, T. V., Jang, I.-H., Grosser, T., FitzGerald, G. A., Daley, G. Q., Orkin, S. H., & Zon, L. I.
Venue
Nature
Published
2007-06
Volume
447
Issue
7147
Pages
1007-1011
ISSN
  • 0028-0836
  • 1476-4687
Cited by
1,029
References
1
Language
en

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CoChat. (2026). Citation check: Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. https://app.cochat.ai/papers/10.1038/nature05883
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North, T. E., Goessling, W., Walkley, C. R., Lengerke, C., Kopani, K. R., Lord, A. M., Weber, G. J., Bowman, T. V., Jang, I.-H., Grosser, T., FitzGerald, G. A., Daley, G. Q., Orkin, S. H., & Zon, L. I. (2007). Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature. https://doi.org/10.1038/nature05883