Ketone bodies as signaling metabolites

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Sirtuins as regulators of metabolism and healthspan

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Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet

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Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

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HDAC2 negatively regulates memory formation and synaptic plasticity

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Ketogenic diet causes bone loss in growing and adult mice and reduces the skeletal response to exercise

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Pollutant–Diet Interactions Drive Distinct Mechanisms of Tetrabromobisphenol A-Induced Hepatic Insulin Resistance in Zebrafish

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Oral administration of MCT oil reduces anxiety-like behavior and is associated with differences in serum BDNF responses in a rat model of PTSD

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β-Hydroxybutyrate Modulates Metabolic Signaling and Partially Restores Peripheral Circadian Rhythms in High-Fat Diet-Fed Mice

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Ketone bodies in metabolism and signaling: Revisiting the paradigm from biochemistry to pancreatic β-cell regulation

Liu, J., & Xia, L. (2026) · Metabolism and Diseases · doi:10.1016/j.metdis.2026.100005 · Cited by 1

Detection of quantitative trait loci and genetic correlations of lipid reserves and production traits in aging laying hens

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Acetoacetyl-CoA synthetase modulates lipid partitioning and cholesterol-related gene expression in NEFA-challenged neonatal bovine hepatocytes

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Ketone bodies in kidney diseases: novel insights

Dai, W., Zhang, W., Li, H., Gao, Y., Xiao, L., Chen, Y., & He, L. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1738916 · Cited by 1

Ketogenic diet and Parkinson’s disease

Ye, Y., Li, S., & Chen, T. (2026) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2026.1914756 · Cited by 1

Adipocyte-derived β-hydroxybutyrate confers metabolic resilience in multiple myeloma

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The Emerging Role of Epigenetics on Dietary Treatment for Epilepsy

Landgrave-Gómez, J., Vargas-Romero, F., Mercado-Gómez, O. F., & Guevara‐Guzmán, R. (2017) · Current Nutrition Reports · doi:10.1007/s13668-017-0189-7 · Cited by 1

The Ketone Body Beta-Hydroxybutyrate in Starvation

Rojas‐Morales, P., & Pedraza‐Chaverrí, J. (2017) · Springer eBooks · doi:10.1007/978-3-319-40007-5_51-1 · Cited by 1

Contemporary Advances in Myocardial Metabolic Imaging and Their Impact on Clinical Care: a Focus on Positron Emission Tomography (PET)

Bois, J. P., Gropler, R. J., & Peterson, L. R. (2018) · Current Cardiovascular Imaging Reports · doi:10.1007/s12410-018-9444-6 · Cited by 1

The Impact of Carbohydrate Restriction and Nutritional Ketosis on Cardiovascular Health

Lowe, D. A., Corbit, K. C., & Weiss, E. J. (2021) · Contemporary cardiology · doi:10.1007/978-3-030-78177-4_5 · Cited by 1

Ketogenic Diet as Adjunctive Therapy for Malignant Brain Cancer

Scheck, A. C., & Syed, N. (2022) · Oxford University Press eBooks · doi:10.1093/med/9780197501207.003.0015 · Cited by 1

Ketogenic diet and testosterone increase: Is the increased cholesterol intake responsible? To what extent and under what circumstances can there be benefits?

Santos, H. O. (2017) · HORMONES · doi:10.14310/horm.2002.1745 · Cited by 1

Overview of Ketone-Based Metabolism

D’Agostino, D. P. (2016) · doi:10.1093/med/9780190497996.003.0031 · Cited by 1

Keto-Adaptation in Health and Fitness

Hyde, P. N., Miller, V. J., & Volek, J. S. (2016) · Oxford University Press eBooks · doi:10.1093/med/9780190497996.003.0038 · Cited by 1

The metabolites derived from lipids and their effects on human health

Xiu, L., Hung, L.-S., Wang, L., Huang, J., & Wang, X. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-823914-8.00004-5 · Cited by 2

Ketone bodies as treatments for neurological illnesses

Arango-Morales, D., & Arango, N. (2023) · Revista de Fomento Social · doi:10.24875/rmn.22000062 · Cited by 1

Ketone bodies inhibit mast cell degradation and protect against anaphylaxis

Sato, A., Nemoto, H., Matsumoto, T., & Ohira, M. J. (2023) · PharmaNutrition · doi:10.1016/j.phanu.2023.100359 · Cited by 1

Fuelling Life and Managing Surplus: Revisiting Type 2 Diabetes

Gudat, U. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.1002613 · Cited by 1

Raging the War against Rheumatoid Arthritis with Plant-Derived Products: Skepticism to Clinical Development

Hazarika, S., Borah, P., & Deb, P. K. (2024) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9789815238129124030004 · Cited by 1

Influence of sex, age, ethnicity/race, and body mass index on the cerumen volatilome using two data analysis approaches: binary and semiquantitative

Barbosa, J. M. G., David, L. C., de Oliveira, C. G., de Oliveira, A. E., & Filho, N. R. A. (2024) · Molecular Omics · doi:10.1039/d4mo00071d · Cited by 1

Effects of Dietary Medium-Chain Triglyceride Supplementation on the Serum Metabolome of Young Adult and Senior Canines

Pan, Y., Sindelar, M., Stancliffe, E., Shriver, L. P., Middleton, R. P., & Patti, G. J. (2024) · Animals · doi:10.3390/ani14243577 · Cited by 1

A ketogenic diet decreases sevoflurane-induced burst suppression in rats

Siegmann, M. J., Parry, S. I., Lark, A. R. S., Mir, F. A., Choi, J., Carpenter, A. H., Crowley, E. A., White, C. G., Kang, J., Purdon, P. L., et al. (2025) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2025.111274 · Cited by 1

Metabolome and Transcriptome Profiling of Chicory Roots Provide Insights Into Laticifer Development and Specialized Metabolism

Vahabi, K., Balcke, G. U., Hakkert, J. C., Meer, I. M. V. D., Athmer, B., & Tissier, A. F. (2026) · Physiologia Plantarum · doi:10.1111/ppl.70778 · Cited by 1

Epigenetics of Mediterranean Diet: Altering Disease Risk

Ross, S. A. (2016) · Springer eBooks · doi:10.1007/978-3-319-27969-5_15 · Cited by 1

Caloric Restriction and Dietary Treatments of Epilepsy: Mechanistic Insights for Drug Discovery

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Preconditioning lessens high fat induced metabolic syndrome along with markers of increased metabolic capacity in muscle and adipose tissue

Li, S., Zhou, X., Jo, E., Mahzari, A., Fouda, S., Li, D., Zhang, K., & Ye, J. (2018) · Bioscience Reports · doi:10.1042/bsr20181873 · Cited by 1

Ketone Bodies have Significant Effects for Long Years Associated with Human Evolution

Bando, H. (2019) · Institutional Repositories DataBase (IRDB) · Cited by 1

Hyperketonemia as the diagnostic basis for hypothermia: An experimental study in diabetic and control mice

Nogami, M., Nishio, T., Hoshi, T., Toukairin, Y., & Arai, T. (2021) · Legal Medicine · doi:10.1016/j.legalmed.2021.101908 · Cited by 1

Metabolic Responses to Energy-Depleted Conditions

SUZUKI, T., Komatsu, T., Shibata, H., & Inagaki, T. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.100391 · Cited by 2

Cancer and Fasting: Can Fasting/Calorie Restriction (CR) or Fasting-Mimicking Diet (FMD) Help Fight Cancer? Molecular Basis of Fasting Response

Gacche, R. N. (2021) · Springer eBooks · doi:10.1007/978-981-16-6050-4_15 · Cited by 1

Zdravje delovno aktivne populacije / Health of the Working-Age Population

Šarabon, N., & Žvanut, B. (2017) · doi:10.26493/978-961-7023-32-9 · Cited by 1

Desarrollo de un modelo de convulsiones farmacorresistentes en ratones

Enrique, A. (2016) · doi:10.35537/10915/58631 · Cited by 1

Examining the Effects of Exogenous Ketones on Exercise Metabolism and Performance in Male Varsity Athletes

Sonnenburg, R. (2018) · UWSpace (University of Waterloo) · Cited by 1

Identification and characterization of the gene profile in diabetes induced erectile dysfunction rat modelPreprint

Zhu, Z., Li, X., Cao, X., Qin, H., Yue, D., Liu, D., Tan, G., Xuan, X., & Zhu, H. (2022) · Research Square · doi:10.21203/rs.3.rs-1372202/v1 · Cited by 1

Mitochondria Inspire a LifestylePreprint

Krämer, P., & Bressan, P. (2018) · doi:10.31234/osf.io/t49eg · Cited by 2

Deep multi-omic profiling reveals extensive mitochondrial remodeling driven by glycemia in early diabetic kidney diseasePreprint

Granata, C., Thallas‐Bonke, V., Caruana, N. J., Huynh, K., Qin, C. X., Laskowski, A., Snelson, M., Anthonisz, J., Jap, E., Ramm, G., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.10.26.564228 · Cited by 1

Exploring the potential impact of non-invasive modifications of the Gut Microbiome on Cancer Immunotherapy – a narrative reviewPreprint

David, A., & Ari, S. L. (2024) · Preprints.org · doi:10.20944/preprints202401.0594.v1

Ketone body b-Hydroxybutyrate does not extend lifespan, but upregulates fecundity in food-limited Daphnia , with a transgenerational effectPreprint

Pearson, A. C., Bhadra, S., & Yampolsky, L. Y. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.18.633735 · Cited by 1

Acidosis Licenses the NLRP3 Inflammasome-Inhibiting Effects of Beta-Hydroxybutyrate and Short-Chain Carboxylic AcidsPreprint

Mank, M. M., Zoller, K. A., Fastiggi, V. A., Ather, J. L., & Poynter, M. E. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.01.650510 · Cited by 1

Stiffness sensing fuels matrix-driven metabolic reboot for kidney repair and regenerationPreprint

Gui, Y., Wang, Y. Y., Li, W., Liu, J.-J., Zheng, K., Li, J., Schaffer, H. W., Jones, C. B., Mallari, S. M., Yu, Y., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.22.660927 · Cited by 1

Towards understanding organ-derived metabolic signatures in blood

Kuich, H. (2014) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-11635

Effects of glucose and fatty acids interactions on glucose metabolism pathways in human trophoblasts

Franco, C. B. (2015) · ANU Open Research (Australian National University) · doi:10.25911/5d6e4af2a46b5

Studying regulation of Mct7 under nutrient deprivation in vitro using a mammalian cell culture model

Volkert, C. R. (2014) · University of Minnesota Digital Conservancy (University of Minnesota)

Topología molecular aplicada a la búsqueda de nuevos fármacos para el tratamiento de la epilepsia refractaria

Ianni, M. E. D. (2015) · doi:10.35537/10915/51575

Type I Diabetes and Celiac Disease

Ettinger, S. E. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803013-4.00003-x

E2F6: A Unique Regulator of Post-natal Cardiac Growth, Death, and Function

Major, J. L. (2017) · uO Research (University of Ottawa) · doi:10.20381/ruor-20294

Uso de inibidores das histonas deacetilases na transferência nuclear de células somáticas em bovinos

Sangalli, J. R. (2016) · doi:10.11606/t.10.2016.tde-05102016-140858

Ketogenic diet and its impact on mental processes of working population

Grom, G. (2017) · doi:10.26493/978-961-7023-32-9.63-71

The ketogenic diet–defining a role in cancer therapy

Tan-Shalaby, J. L. (2018) · Integrative Food Nutrition and Metabolism · doi:10.15761/ifnm.1000209

Calorie Restriction, Health and Longevity

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Concentrações fisiológicas de corpos cetônicos não induzem browning em adipócitos/tecido adiposo: estudos in vitro e in vivo.

Caminhotto, R. D. O. (2019) · doi:10.11606/t.42.2019.tde-25032019-110820

Metabolic phenotyping of the pressure-overloaded heart

Geraets (2020) · Research Publications (Maastricht University) · doi:10.26481/dis.20200124ig

Microglial adipobiology: a new concept for understanding the adipose tissue-brain crosstalk in health and disease

Zhelezov, M. (2019) · Adipobiology · doi:10.14748/adipo.v10.6538

From brain to muscle and back : novel approaches to harness the benefits of exercise

Kelahmetoglu, Y. (2020) · Figshare

Tissue Specific Roles of Fatty Acid Oxidation

Lee, J. (2016)

Breath acetone as a potential marker of metabolic flexibility

Ivanova, A. M., & Ginak, A. I. (2020) · Butlerov Communications · doi:10.37952/roi-jbc-01/20-61-1-111

Comparative study on the metabolome of the most prevalent fish pathogen, Streptococcus iniae at different temperatures using 1 H nuclear magnetic resonance

Mardanipuor, M., Rahimi, R., Hajirezaee, S., & Nikookhah, F. (2021) · Aquaculture Research · doi:10.1111/are.15308

Fasting for Cardiovascular Health

Epstein, E., Maysent, K., & Wilkinson, M. J. (2021) · Contemporary cardiology · doi:10.1007/978-3-030-78177-4_9

Lipidomics: New Frontier of the Ketogenic Diet

Lodi, A., & Cenci, L. (2021) · International Journal of Nutrition and Food Sciences · doi:10.11648/j.ijnfs.20211005.11

Contribution of Ketone Oxidation on Energy Production in the Failing Heart

Pherwani, S. (2021) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3-2dz6-3t18

Memory Enhancers

Halevas, E. G., Katsipis, G., & Pantazaki, Α. A. (2019) · Springer eBooks · doi:10.1007/978-981-13-3759-8_7

Fasting

Myers, T. R., & Goldhamer, A. C. (2020) · Elsevier eBooks · doi:10.1016/b978-0-323-43044-9.00037-6

Overview

D’Agostino, D. P. (2022) · doi:10.1093/med/9780197501207.003.0032

Identification and Characterization of The Gene Profile in Diabetes Induced Erectile Dysfunction Rat ModelPreprint

Zhu, Z., Li, X., Cao, X., Qin, H., Yue, D., Liu, D., Tan, G., Xuan, X., & Zhu, H. (2022) · Research Square · doi:10.21203/rs.3.rs-1372202/v2

Intermittent Exogenous Ketosis for Athletic Performance, Recovery, and Adaptation

Stubbs, B. J., & Hespel, P. (2022) · Oxford University Press eBooks · doi:10.1093/med/9780197501207.003.0040

Ketogenic Diet and Ketones for the Treatment of Traumatic Brain and Spinal Cord Injury

Streijger, F., Plunet, W. T., & Tetzlaff, W. (2016) · Oxford University Press eBooks · doi:10.1093/med/9780190497996.003.0016

Ketogenic Diet as Adjunctive Therapy for Malignant Brain Cancer

Woolf, E. C., & Scheck, A. C. (2016) · doi:10.1093/med/9780190497996.003.0013

Nutrition: Macronutrient metabolism

Frayn, K. N., & Evans, R. D. (2020) · doi:10.1093/med/9780198746690.003.0218

Ketone Bodies

Morio, B., & Wolfe, R. R. (2015) · Wiley eBooks · doi:10.1002/9780470015902.a0003819.pub2

Faculty Opinions recommendation of Diet modulates brain network stability, a biomarker for brain aging, in young adults.

Lafer, E. M. (2020) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.737471092.793572067

NEW PERSPECTIVES OF KETOGENIC DIET

TABUKASHVILI, R., KAPETIVADZE, V., Silagadze, T. K., Kuparadze, M., MAGLAPERIDZE, Z., LAZASHVILI, T., & AVALIANI, I. (2022) · EXPERIMENTAL & CLINICAL MEDICINE GEORGIA · doi:10.52340/jecm.2022.06.20

Role Fasting In Metabolism And Tumor Progressive

Waheed, Z. A., Sarhan, N. H., Shaker, M. M., AL-Zubaidy, I. M. K., & Idreess, H. G. (2022) · Medical Science Journal for Advance Research · doi:10.46966/msjar.v3i2.40

Extracellular Matrix and Protein Phosphorylation Dysregulation Related to Diabetes‐Induced Erectile Dysfunction

Zhu, Z., Li, X., Cao, X., Qin, H., Yue, D., Liu, D., Tan, G., Xuan, X., & Zhu, H. (2023) · Andrologia · doi:10.1155/2023/5488279

Ketone Esters and Their Effects on Carbohydrate Metabolism During Exercise

Gonzalez, J. T. (2023) · Journal of Nutrition · doi:10.1016/j.tjnut.2023.04.003

Neurology

Hoffmann, M. W., Cywes, R., Childers, A. M., Kossoff, M. M., Kossoff, E. H., Perlmutter, D., Phillips, M. C. L., Edes, G., Berger, A., Stanton, A. A., et al. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-821617-0.00006-1

Avaliação do impacto da redução significativa de peso pela dieta cetogênica de muito baixa caloria nos parâmetros metabólicos, inflamatórios, hormonais e seminais de homens obesos

Renck, A. C. (2023) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2023.tde-13062023-142212

Avaliação dos efeitos do etanol e de seus metabólitos sobre a resposta efetora e moduladora de macrófagos ao fungo dimórfico "Paracoccidioides brasiliensis"

de Castro, L. F. (2019) · doi:10.47749/t/unicamp.2019.1169628

Automated Multi-Injection Gas Chromatography-Photoionization Detection (AMI-GC-PID) for Qualitative and Quantitative Determination of Urinary Acetone

Ding, Y., Song, Y., Xu, W. L., Zhang, Q., Li, Y., Zhang, Q., Liang, Q., Bao, X., Ge, D., Lü, Y., et al. (2024) · Analytical Letters · doi:10.1080/00032719.2024.2343378

Heterogeneous metabolomic aging across the same age and prediction of health outcomePreprint

Jia, X., Fan, J., Wu, X., Cao, X., Ma, L., Abdelrahman, Z., Bizzarri, D., van den Akker, E. B., Slagboom, P. E., Deelen, J., et al. (2024) · medRxiv · doi:10.1101/2024.04.22.24306156

Small Ketogenic Rescues the Brain

Satoh, T. (2024) · Springer eBooks · doi:10.1007/978-3-031-54150-6_7

The effect of dietary sodium octanoate on Ghrelin concentration and feed intake in chickens and turkeys: a comparative study

Taofeek, N., Thompson, D., Rowland, J., Sanmartin, P., Cerón-Romero, N., Vroonland, E., Cintron, O., Rushing, M., McKee, K., Lopez, S., et al. (2024) · Poultry Science · doi:10.1016/j.psj.2024.103962

Fasting, intermittent fasting, time-restricted feeding, calorie restriction: Facts or fads?

Visioli, F. (2024) · Elsevier eBooks · doi:10.1016/b978-0-12-824005-2.00009-9

Ketogenic interventions restore cognition and modulate peripheral metabolic dysfunctions in Alzheimer’s disease mouse modelsPreprint

M’Bra, P. E. H., Hamilton, L. K., Moquin‐Beaudry, G., Aubin, M., Mangahas, C. L., Pratesi, F., Brunet‐Ratnasingham, E., Castonguay, A., Mailloux, S., Galoppin, M., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.04.610637

Intermittent fasting: Effectiveness and safety. A review

Altashina, M. V., Иванникова, Е. В., & Troshina, E. A. (2024) · Terapevticheskii arkhiv · doi:10.26442/00403660.2024.10.202884

Fejezetek az alkohológia tárgyköréből

Kalapos, M. P. (2024) · Orvosi Hetilap · doi:10.1556/650.2024.33165

The Ketogenic Diet and Stroke

Ajagun, E. J., Asuku, A. O., Oyerinde, T. O., Sangodipe, H. A., Sanusi, W., Jayeoba, L. A., & Abdulsalam, T. A. (2024) · Nutritional neurosciences · doi:10.1007/978-981-97-6818-9_10

Ketogenic interventions prevent alterations of the gut microbiome in transgenic Alzheimer’s Disease micePreprint

M’Bra, P. E. H., Avino, M., Lim, E. N. K., Mayhue, M., Balthazar, P., Aumont, A., Prévost, K., Massé, É., & Fernandes, K. J. L. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.02.25.640129

Harnessing Exercise for Chronic Kidney Disease: Integrating Molecular Pathways, Epigenetics, and Gene-Environment Interactions

Baek, K.-W., Cho, J., Kim, J. H., & Kim, J.-S. (2025) · Biocell · doi:10.32604/biocell.2025.064916 · Cited by 1

Fonksiyonel Beslenme Yaklaşımları ve Mikrobiyota İlişkisi

Bulut, E. N., & Demir, N. (2025) · Özgür Yayınları eBooks · doi:10.58830/ozgur.pub813.c3426

Exhaled breath condensates for identifying brain disease–specific metabolites of potential biomarkers: Taking Parkinson's disease as an example

Wang, A. T., Gao, Y., Li, Y., Liu, N., Gao, J., Wang, H., Sun, J., Tao, C., Meng, F., & Hu, L. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.167565

Nutritional strategies supporting brain health: Intermittent fasting, caloric restriction, and the microbiota–gut–brain axis

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Transient juvenile hypoglycemia in GH insensitive Laron syndrome pigs is associated with insulin hypersensitivity

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