Therapeutic peptides.

Serum Albumin

Peters, T. (1985) · Advances in protein chemistry · doi:10.1016/s0065-3233(08)60065-0 · Cited by 2,183 · see citing works

Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model

Arap, W., Pasqualini, R., & Ruoslahti, E. I. (1998) · Science · doi:10.1126/science.279.5349.377 · Cited by 2,040 · see citing works

Genes Expressed in Human Tumor Endothelium

Croix, B. S., Rago, C., Velculescu, V. E., Traverso, G., Romans, K. E., Montgomery, E. A., Lal, A., Riggins, G. J., Christoph Lengauer, C., Vogelstein, B., et al. (2000) · Science · doi:10.1126/science.289.5482.1197 · Cited by 1,845 · see citing works

Microfabricated Microneedles: A Novel Approach to Transdermal Drug Delivery

Henry, S., McAllister, D. V., Allen, M. G., & Prausnitz, M. R. (1998) · Journal of Pharmaceutical Sciences · doi:10.1021/js980042+ · Cited by 1,350 · see citing works

Organ targeting In vivo using phage display peptide libraries

Pasqualini, R., & Ruoslahti, E. I. (1996) · Nature · doi:10.1038/380364a0 · Cited by 1,221 · see citing works

Anti-cancer activity of targeted pro-apoptotic peptides

Ellerby, H. M., Arap, W., Ellerby, L., Kain, R., Andrusiak, R. L., del Rio, G., Krajewski, S., Lombardo, C. R., Rao, R. V., Ruoslahti, E. I., et al. (1999) · Nature Medicine · doi:10.1038/12469 · Cited by 936 · see citing works

β-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: Implications for Alzheimer's therapy

Soto, C. A., Sigurdsson, E. M., Morelli, L., Kumar, R., Castaño, E. M., & Frangione, B. (1998) · Nature Medicine · doi:10.1038/nm0798-822 · Cited by 874 · see citing works

Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature.

Chang, S. S., Reuter, V. E., Heston, W. D. W., Bander, N. H., Grauer, L. S., & Gaudin, P. B. (1999) · PubMed · Cited by 807 · see citing works

Ultrasound-Mediated Transdermal Protein Delivery

Mitragotri, S., Blankschtein, D., & Langer, R. (1995) · Science · doi:10.1126/science.7638603 · Cited by 794 · see citing works

Tryptophan zippers: Stable, monomeric β-hairpins

Cochran, A. G., Skelton, N. J., & Starovasnik, M. A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.091100898 · Cited by 741 · see citing works

Solid‐Phase Peptide Synthesis

Merrifield, R. B. (1969) · Advances in enzymology and related areas of molecular biology/Advances in enzymology and related subjects · doi:10.1002/9780470122778.ch6 · Cited by 691 · see citing works

Steps toward mapping the human vasculature by phage display

Arap, W., Kolonin, M. G., Trepel, M., Lahdenranta, J., Cardó‐Vila, M., Giordano, R. J., Mintz, P. J., Ardelt, P., Yao, V. J., Vidal, C. I., et al. (2002) · Nature Medicine · doi:10.1038/nm0202-121 · Cited by 606 · see citing works

De Novo Antimicrobial Peptides with Low Mammalian Cell Toxicity

Javadpour, M. M., Juban, M. M., Lo, W. C. J., Bishop, S. M., Alberty, J. B., Cowell, S. M., Becker, C. L., & McLaughlin, M. L. (1996) · Journal of Medicinal Chemistry · doi:10.1021/jm9509410 · Cited by 597 · see citing works

Functional Mimicry of a Protein Hormone by a Peptide Agonist: The EPO Receptor Complex at 2.8 Å

Livnah, O., Stura, E. A., Johnson, D. L., Middleton, S. A., Mulcahy, L. S., Wrighton, N. C., Dower, W. J., Jolliffe, L. K., & Wilson, I. A. (1996) · Science · doi:10.1126/science.273.5274.464 · Cited by 588 · see citing works

Transgenic anopheline mosquitoes impaired in transmission of a malaria parasite

Ito, J., Ghosh, A., Moreira, L. A., Wimmer, E. A., & Jacobs‐Lorena, M. (2002) · Nature · doi:10.1038/417452a · Cited by 573 · see citing works

Tumor targeting with a selective gelatinase inhibitor

Koivunen, E., Arap, W., Valtanen, H., Rainisalo, A., Medina, O. P., Heikkilä, P., Kantor, C., Gahmberg, C. G., Salo, T. A., Konttinen, Y. T., et al. (1999) · Nature Biotechnology · doi:10.1038/11703 · Cited by 567 · see citing works

Albumin Binding as a General Strategy for Improving the Pharmacokinetics of Proteins

Dennis, M. S., Zhang, M., Meng, Y., Kadkhodayan, M., Kirchhofer, D., Combs, D., & Damico, L. A. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205854200 · Cited by 508 · see citing works

Ultraflexible vesicles, Transfersomes, have an extremely low pore penetration resistance and transport therapeutic amounts of insulin across the intact mammalian skin

Cevc, G., Gebauer, D., Stieber, J., Schätzlein, A. G., & Blume, G. (1998) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(97)00177-6 · Cited by 479 · see citing works

Inhibition of Alzheimer's Amyloidosis by Peptides That Prevent β-Sheet Conformation

Soto, C. A., Kindy, M. S., Baumann, M., & Frangione, B. (1996) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1996.1413 · Cited by 432 · see citing works

Established Human Papillomavirus Type 16-Expressing Tumors Are Effectively Eradicated Following Vaccination with Long Peptides

Zwaveling, S., Mota, S. C. F., Nouta, J., Johnson, M., Lipford, G. B., Offringa, R., van der Burg, S. H., & Melief, C. J. M. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.1.350 · Cited by 416 · see citing works

Enhancement of tumor necrosis factor α antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13)

Curnis, F., Sacchi, A., Borgna, L., Magni, F., Gasparri, A. M., & Corti, A. (2000) · Nature Biotechnology · doi:10.1038/81183 · Cited by 415 · see citing works

Oral delivery of insulin using pH‐responsive complexation gels

Lowman, A. M., Morishita, M., Kajita, M., NAGAI, T., & Peppas, N. A. (1999) · Journal of Pharmaceutical Sciences · doi:10.1021/js980337n · Cited by 407 · see citing works

[21] Phage display for selection of novel binding peptides

Sidhu, S. S., Lowman, H. B., Cunningham, B. C., & Wells, J. A. (2000) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(00)28406-1 · Cited by 403 · see citing works

Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics.

Haubner, R., Wester, H. J., Burkhart, F., Senekowitsch–Schmidtke, R., Weber, W., Goodman, S. L., Kessler, H., & Schwaiger, M. (2001) · PubMed · Cited by 381 · see citing works

Antimicrobial peptides of vertebrates

Ganz, T., & Lehrer, R. I. (1998) · Current Opinion in Immunology · doi:10.1016/s0952-7915(98)80029-0 · Cited by 374 · see citing works

Antimicrobial Peptides: Properties and Applicability

Hof, W. V. ‘., Veerman, E. C. I., Helmerhorst, E. J., & Amerongen, A. V. N. (2001) · Biological Chemistry · doi:10.1515/bc.2001.072 · Cited by 357 · see citing works

Serological identification of human tumor antigens

Şahin, U., Türeci, Ö., & Pfreundschuh, M. G. (1997) · Current Opinion in Immunology · doi:10.1016/s0952-7915(97)80053-2 · Cited by 314 · see citing works

Therapeutic cancer targeting peptides

Aina, O. H., Sroka, T. C., Chen, M., & Lam, K. S. (2002) · Biopolymers · doi:10.1002/bip.10257 · Cited by 313 · see citing works

Targeting the prostate for destruction through a vascular address

Arap, W., Haedicke, W., Bernasconi, M., Kain, R., Rajotte, D., Krajewski, S., Ellerby, H. M., Bredesen, D. E., Pasqualini, R., & Ruoslahti, E. I. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.241655998 · Cited by 284 · see citing works

Reversion of prion protein conformational changes by synthetic b-sheet breaker peptides

Soto, C. A., Kascsak, R. J., Saborı́o, G. P., Aucouturier, P., Wısnıewskı, T., Prelli, F. C., Kascsak, R., Méndez, E., Harris, D. A., Ironside, J. W., et al. (2000) · The Lancet · doi:10.1016/s0140-6736(99)11419-3 · Cited by 274 · see citing works

Effects of PEG conjugation on insulin properties

Hinds, K. D., & Kim, S. W. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00025-x · Cited by 240 · see citing works

Reduction of amyloid load and cerebral damage in transgenic mouse model of Alzheimer's disease by treatment with a β‐sheet breaker peptide

Permanne, B., Adessi, C., Saborı́o, G. P., Fraga, S., Frossard, M., Dorpe, J. V., Dewachter, I., Banks, W. A., LEUVEN, F. V., & Soto, C. A. (2002) · The FASEB Journal · doi:10.1096/fj.01-0841fje · Cited by 218 · see citing works

Exendin-4 and Glucagon-like-peptide-1: NMR Structural Comparisons in the Solution and Micelle-Associated States

Neidigh, J. W., Fesinmeyer, R. M., Prickett, K. S., & Andersen, N. H. (2001) · Biochemistry · doi:10.1021/bi010902s · Cited by 206 · see citing works

Structure of solid tumors and their vasculature: implications for therapy with monoclonal antibodies.

Dvorak, H. F., Nagy, J. A., & Dvořàk, A. M. (1991) · PubMed · Cited by 202 · see citing works

Targeting Plasmodium ligands on mosquito salivary glands and midgut with a phage display peptide library

Ghosh, A. K., Ribolla, P. E. M., & Jacobs‐Lorena, M. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.241491198 · Cited by 196 · see citing works

Cloning, expression, genomic localization, and enzymatic activities of the mouse homolog of prostate-specific membrane antigen/NAALADase/folate hydrolase

Bacich, D. J., Pinto, J. T., Tong, W. P., & Heston, W. D. W. (2001) · Mammalian Genome · doi:10.1007/s003350010240 · Cited by 178 · see citing works

Lecithin vesicular carriers for transdermal delivery of cyclosporin A

Guo, Z., Ping, Q. N., Sun, G., & Jiao, C. (2000) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(99)00361-0 · Cited by 158 · see citing works

Improved Lung Delivery from a Passive Dry Powder Inhaler Using an Engineered PulmoSphere® Powder

Duddu, S. P., Sisk, S. A., Walter, Y. H., Tarara, T. E., Trimble, K. R., Clark, A. R., Eldon, M. A., Elton, R. C., Pickford, M., Hirst, P. H., et al. (2002) · Pharmaceutical Research · doi:10.1023/a:1015322616613 · Cited by 150 · see citing works

Three-Dimensional Structure of RTD-1, a Cyclic Antimicrobial Defensin from Rhesus Macaque Leukocytes,

Trabi, M., Schirra, H. J., & Craik, D. J. (2001) · Biochemistry · doi:10.1021/bi002028t · Cited by 143 · see citing works

Effect of sonication parameters on transdermal delivery of insulin to hairless rats

Boucaud, A., Garrigue, M. A., Machet, L., Vaillant, L., & Patat, F. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(02)00054-8 · Cited by 133 · see citing works

Positional Isomers of Monopegylated Interferon α-2a: Isolation, Characterization, and Biological Activity

Monkarsh, S. P., Ma, Y., Aglione, A., Bailon, P., Ciolek, D., Debarbieri, B., Graves, M. C., Hollfelder, K., Michel, H., Palleroni, A. V., et al. (1997) · Analytical Biochemistry · doi:10.1006/abio.1997.2128 · Cited by 114 · see citing works

The structure of T6human insulin at 1.0 Å resolution

Smith, G. D., Pangborn, W. A., & BLESSING, R. H. (2003) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444902023685 · Cited by 113 · see citing works

Iontophoresis-Based Transdermal Delivery Systems

Kanikkannan, N. (2002) · BioDrugs · doi:10.2165/00063030-200216050-00003 · Cited by 111 · see citing works

Development of oral insulin: progress and current status

Still, J. (2002) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.207 · Cited by 110 · see citing works

Potent Antithrombin Activity and Delayed Clearance From the Circulation Characterize Recombinant Hirudin Genetically Fused to Albumin

Syed, S., Schuyler, P. D., Kulczycky, M., & Sheffield, W. P. (1997) · Blood · doi:10.1182/blood.v89.9.3243 · Cited by 108 · see citing works

Chemotherapy targeted to tumor vasculature

Arap, W., Pasqualini, R., & Ruoslahti, E. (1998) · Current Opinion in Oncology · doi:10.1097/00001622-199811000-00014 · Cited by 107 · see citing works

The evolving role of oral insulin in the treatment of diabetes using a novel RapidMist? System

Modi, P. J., Mihic, M., & Lewin, A. J. (2002) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.208 · Cited by 106 · see citing works

Crystal Structure of Human Insulin-like Growth Factor-1: Detergent Binding Inhibits Binding Protein Interactions

Vajdos, F. F., Ultsch, M. H., Schaffer, M. L., Deshayes, K., Liu, J., Skelton, N. J., & de Vos, A. M. (2001) · Biochemistry · doi:10.1021/bi0109111 · Cited by 99 · see citing works

IB-367, a Protegrin Peptide with In Vitro and In Vivo Activities against the Microflora Associated with Oral Mucositis

Mosca, D. A., Hurst, M. A., So, W., Viajar, B. S. C., Fujii, C. A., & Falla, T. J. (2000) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.44.7.1803-1808.2000 · Cited by 97 · see citing works

Peptides—synthesis, structures and applications

Wallach, J. (1996) · Biochemical Education · doi:10.1016/s0307-4412(97)80792-3 · Cited by 91 · see citing works

Peptide Inhibitors of Beta Amyloid Aggregation

Findeis, M. A. (2002) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026024607508 · Cited by 90 · see citing works

Molecular Mimics of Insulin-like Growth Factor 1 (IGF-1) for Inhibiting IGF-1: IGF-Binding Protein Interactions

Lowman, H. B., Chen, Y. M., Skelton, N. J., Mortensen, D. L., Tomlinson, E. E., Sadick, M. D., Robinson, I. C. A. F., & CLARK, R. G. (1998) · Biochemistry · doi:10.1021/bi980426e · Cited by 89 · see citing works

In Vivo Lung Deposition of Hollow Porous Particles from a Pressurized Metered Dose Inhaler

Hirst, P. H., Pitcairn, G. R., Weers, J. G., Tarara, T. E., Clark, A. R., Dellamary, L. A., Hall, G., Shorr, J. S., & Newman, S. P. (2002) · Pharmaceutical Research · doi:10.1023/a:1014482615914 · Cited by 89 · see citing works

Multiepitope CD8+ T cell response to a NY-ESO-1 peptide vaccine results in imprecise tumor targeting

Dutoit, V., Taub, R. N., Papadopoulos, K. P., Talbot, S. M., Keohan, M. L., Brehm, M., Gnjatic, S., Harris, P. E., Bisikirska, B. C., Guillaume, P., et al. (2002) · Journal of Clinical Investigation · doi:10.1172/jci16428 · Cited by 88 · see citing works

Oral Delivery of Biologically Active Parathyroid Hormone

Leone‐Bay, A., Sato, M., Paton, D. R., Hunt, A. H., Sarubbi, D., Carozza, M., Chou, J., McDonough, J., & Baughman, R. (2001) · Pharmaceutical Research · doi:10.1023/a:1010936227570 · Cited by 87 · see citing works

The Factor VII Zymogen Structure Reveals Reregistration of β Strands during Activation

Eigenbrot, C. W., Kirchhofer, D., Dennis, M. S., Santell, L., Lazarus, R. A., Stamos, J. L., & Ultsch, M. H. (2001) · Structure · doi:10.1016/s0969-2126(01)00624-4 · Cited by 85 · see citing works

Isolation, Characterization, and Stability of Positional Isomers of Mono-PEGylated Salmon Calcitonins

Lee, K. C., Moon, S. C., Park, M. O., Lee, J. T., Na, D. H., Yoo, S. D., Lee, H. S., & DeLuca, P. P. (1999) · Pharmaceutical Research · doi:10.1023/a:1018861616465 · Cited by 80 · see citing works

Transdermal iontophoretic delivery of bovine insulin and monomeric human insulin analogue

Kanikkannan, N., Singh, J., & Ramarao, P. (1999) · Journal of Controlled Release · doi:10.1016/s0168-3659(98)00184-9 · Cited by 78 · see citing works

Radio-labeled receptor-binding peptides: A new class of radiopharmaceuticals

Boerman, O. C., Oyen, W. J. G., & Corstens, F. H. M. (2000) · Seminars in Nuclear Medicine · doi:10.1053/snuc.2000.7441 · Cited by 76 · see citing works

Inhibition of Interactions and Interconversions of Prion Protein Isoforms by Peptide Fragments from the C-terminal Folded Domain

Horiuchi, M., Baron, G. S., Xiong, L., & Caughey, B. W. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m100288200 · Cited by 70 · see citing works

Pegylated recombinant human epidermal growth factor (rhEGF) for sustained release from biodegradable PLGA microspheres

Kim, T. H. (2002) · Biomaterials · doi:10.1016/s0142-9612(01)00365-9 · Cited by 68 · see citing works

Transdermal Delivery of Insulin in Mice by Using Lecithin Vesicles as a Carrier

Guo, Q. P. J. (2000) · Drug Delivery · doi:10.1080/107175400266687 · Cited by 65 · see citing works

Albumin affinity tags increase peptide half-life in vivo

Koehler, M. F. T., Zobel, K., Beresini, M. H., Caris, L. D., Combs, D. L., Paasch, B. D., & Lazarus, R. A. (2002) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(02)00610-8 · Cited by 65 · see citing works

Rapid Identification of Small Binding Motifs with High-Throughput Phage Display

Deshayes, K., Schaffer, M. L., Skelton, N. J., Nakamura, G. R., Kadkhodayan, S., & Sidhu, S. S. (2002) · Chemistry & Biology · doi:10.1016/s1074-5521(02)00129-1 · Cited by 65 · see citing works

Preparation and Characterization of Mono-PEGylated Epidermal Growth Factor: Evaluation of in Vitro Biologic Activity

Lee, H., & Park, T. G. (2002) · Pharmaceutical Research · doi:10.1023/a:1016113117851 · Cited by 57 · see citing works

Phage-displayed Peptides Bind to the Malarial Protein Apical Membrane Antigen-1 and Inhibit the Merozoite Invasion of Host Erythrocytes

Li, F., Dluzewski, A. R., Coley, A. M., Thomas, A. W., Tilley, L. M., Anders, R. F., & Foley, M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207985200 · Cited by 55 · see citing works

Penetration of Tumor Tissue by Antibodies and Other Immunoproteins

Shockley, T. R., LIN, K., Nagy, J. A., Tompkins, R. G., Dvorak, H. F., & Yarmush, M. L. (1991) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1991.tb27257.x · Cited by 54 · see citing works

A Novel Approach for the Identification of Unique Tumor Vasculature Binding Peptides Using an E. coli Peptide Display Library

Brown, C. K., Modzelewski, R. A., Johnson, C. S., & Wong, M. K. K. (2000) · Annals of Surgical Oncology · doi:10.1007/s10434-000-0743-0 · Cited by 52 · see citing works

Prevention of bone loss in ovariectomized rats by pulsatile transdermal iontophoretic administration of human PTH(1–34)

Suzuki, Y., Nagase, Y., Iga, K., Kawase, M., Oka, M., Yanai, S., Matsumoto, Y., Nakagawa, S., Fukuda, T., Adachi, H., et al. (2002) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.10019 · Cited by 51 · see citing works

A Novel Family of Hairpin Peptides That Inhibit IgE Activity by Binding to the High-Affinity IgE Receptor

Nakamura, G. R., Starovasnik, M. A., Reynolds, M. E., & Lowman, H. B. (2001) · Biochemistry · doi:10.1021/bi0109360 · Cited by 50 · see citing works

Stable “zeta” peptides that act as potent antagonists of the high-affinity IgE receptor

Nakamura, G. R., Reynolds, M. E., Chen, Y. M., Starovasnik, M. A., & Lowman, H. B. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.022635599 · Cited by 49 · see citing works

Peptide-based cancer vaccines

Machiels, J., van Baren, N., & Marchand, M. (2002) · Seminars in Oncology · doi:10.1053/sonc.2002.35244 · Cited by 48 · see citing works

Structure−Function Analysis of a Phage Display-Derived Peptide That Binds to Insulin-like Growth Factor Binding Protein 1

Skelton, N. J., Chen, Y. M., Dubree, N., Quan, C. L., Jackson, D. Y., Cochran, A. G., Zobel, K., Deshayes, K., Baca, M., Pisabarro, M. T., et al. (2001) · Biochemistry · doi:10.1021/bi0103866 · Cited by 40 · see citing works

Synthetic peptides as cancer vaccines

Sundaram, R., Dakappagari, N. K., & Kaumaya, P. T. P. (2002) · Biopolymers · doi:10.1002/bip.10258 · Cited by 34 · see citing works

Receptor-Mediated Targeting of Spray-Dried Lipid Particles Coformulated with Immunoglobulin and Loaded with a Prototype Vaccine

Bot, A. I., Smith, D. J., Bot, S., Dellamary, L. A., Tarara, T. E., Harders, S., Phillips, W. T., Weers, J. G., & Woods, C. M. (2001) · Pharmaceutical Research · doi:10.1023/a:1010988311640 · Cited by 33 · see citing works

Induction of Specific Immune Responses by Polycation-Based Vaccines

Lührs, P., SCHMIDT, W. A., Kutil, R., Buschle, M., Wagner, S. N., Stingl, G., & Schneeberger, A. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.9.5217 · Cited by 31 · see citing works

Evaluation of alternative strategies for optimizing glycemia: progress to date

Cefalu, W. T. (2002) · The American Journal of Medicine · doi:10.1016/s0002-9343(02)01278-0 · Cited by 28 · see citing works

Physical and Chemical Enhancement of Transdermal Delivery of Triptorelin

Nicoli, S., Rimondi, S., Colombo, P., & Santi, P. (2001) · Pharmaceutical Research · doi:10.1023/a:1013003103169 · Cited by 24 · see citing works

Progress toward a Malaria Vaccine: Efficient Induction of Protective Anti-Malaria Immunity

Tsuji, M., Rodrigues, E. G., & Nussenzweig, R. S. (2001) · Biological Chemistry · doi:10.1515/bc.2001.069 · Cited by 23 · see citing works

Secretory Expression of Human Albumin Domains inSaccharomyces cerevisiaeand Their Binding of Myristic Acid and an Acylated Insulin Analogue

Kjeldsen, T., Pettersson, A. F., Drube, L., Kurtzhals, P., Jonassen, I., Havelund, S., Hansen, P. H., & Markussen, J. (1998) · Protein Expression and Purification · doi:10.1006/prep.1998.0876 · Cited by 19 · see citing works

Site Specific 1:1 Opioid:Albumin Conjugate with in Vitro Activity and Long in Vivo Duration

Holmes, D. L., Thibaudeau, K., L'Archevêque, B., Milner, P. G., Ezrin, A. M., & Bridon, D. P. (2000) · Bioconjugate Chemistry · doi:10.1021/bc0000233 · Cited by 19 · see citing works

Phage Display of Peptide Libraries on Protein Scaffolds

Lowman, H. B. (2003) · Humana Press eBooks · doi:10.1385/0-89603-392-9:249 · Cited by 13 · see citing works

The History of Peptide Chemistry

Wieland, T. (1995) · Elsevier eBooks · doi:10.1016/b978-012310920-0/50002-4 · Cited by 7 · see citing works

Trends in peptide drug discovery

Muttenthaler, M., King, G. F., Adams, D. J., & Alewood, P. F. (2021) · Nature Reviews Drug Discovery · doi:10.1038/s41573-020-00135-8 · Cited by 2,022 · see citing works

Synthetic therapeutic peptides: science and market

Vlieghe, P., Lisowski, V., Martínez, J., & Khrestchatisky, M. (2009) · Drug Discovery Today · doi:10.1016/j.drudis.2009.10.009 · Cited by 1,487 · see citing works

Antimicrobial peptides: key components of the innate immune system

Pasupuleti, M., Schmidtchen, A., & Malmsten, M. (2011) · Critical Reviews in Biotechnology · doi:10.3109/07388551.2011.594423 · Cited by 804 · see citing works

Evaluation of the use of therapeutic peptides for cancer treatment

Marqus, S., Pirogova, E., & Piva, T. J. (2017) · Journal of Biomedical Science · doi:10.1186/s12929-017-0328-x · Cited by 513 · see citing works

Novel biotechnological applications of bacteriocins: A review

Balciunas, E. M., Castillo Martinez, F. A., Todorov, S. D., Franco, B. D. G. D. M., Converti, A., & Oliveira, R. P. D. S. (2013) · Food Control · doi:10.1016/j.foodcont.2012.11.025 · Cited by 392 · see citing works

Bioactive Molecules Released in Food by Lactic Acid Bacteria: Encrypted Peptides and Biogenic Amines

Pessione, E., & Cirrincione, S. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00876 · Cited by 333 · see citing works

Peptidomimetics via modifications of amino acids and peptide bonds

Avan, İ., Hall, C. D., & KATRITZKY, A. R. (2014) · Chemical Society Reviews · doi:10.1039/c3cs60384a · Cited by 285 · see citing works

Viral vectors for production of recombinant proteins in plants

Lico, C., Chen, Q., & Santi, L. (2008) · Journal of Cellular Physiology · doi:10.1002/jcp.21423 · Cited by 253 · see citing works

Peptide Phage Display as a Tool for Drug Discovery: Targeting Membrane Receptors

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Antimicrobial peptide production and plant-based expression systems for medical and agricultural biotechnology

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Synthesis of chitosan–polycaprolactone blend for control delivery of ofloxacin drug

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Peptides for Therapy and Diagnosis of Alzheimer's Disease

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Preparation of a novel chitosan-g-poly(acrylamide)/Zn nanocomposite hydrogel and its applications for controlled drug delivery of ofloxacin.

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Potential of a Renin Inhibitory Peptide from the Red Seaweed <i>Palmaria palmata</i> as a Functional Food Ingredient Following Confirmation and Characterization of a Hypotensive Effect in Spontaneously Hypertensive Rats

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PEG-stabilized lipid disks as carriers for amphiphilic antimicrobial peptides

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Tissue Engineering Using Magnetite Nanoparticles

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Small peptides, big world: biotechnological potential in neglected bioactive peptides from arthropod venoms

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Antiviral peptides against the main protease of SARS-CoV-2: A molecular docking and dynamics study

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Peptides Derived from Human Decorin Leucine-rich Repeat 5 Inhibit Angiogenesis

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Mirror image phage display—a method to generate d -peptideligands for use in diagnostic or therapeutical applications

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D‐Peptide and D‐Protein Technology: Recent Advances, Challenges, and Opportunities**

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A novel transferrin receptor-targeted hybrid peptide disintegrates cancer cell membrane to induce rapid killing of cancer cells

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Synthesis of Chemically Modified Bioactive Peptides: Recent Advances, Challenges and Developments for Medicinal Chemistry

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Novel Delivery Systems for Improving the Clinical Use of Peptides

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The use of plants for the production of therapeutic human peptides

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Bacterial display enables efficient and quantitative peptide affinity maturation

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Fabrication of chitosan-g-poly(acrylamide)/CuS nanocomposite for controlled drug delivery and antibacterial activity

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Biological properties of low molecular mass peptide dendrimers

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Animal-Derived Pharmaceutical Proteins

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A novel hybrid peptide targeting EGFR-expressing cancers

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Active targeting of early and mid-stage atherosclerotic plaques using self-assembled peptide amphiphile micelles

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Tumor-Cell-Targeted Methionine-enkephalin Analogues Containing Unnatural Amino Acids: Design, Synthesis, and in Vitro Antitumor Activity

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Amphipathic Peptide-Based Fusion Peptides and Immunoconjugates for the Targeted Ablation of Prostate Cancer Cells

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Genital Herpes: Insights into Sexually Transmitted Infectious Disease

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Anticancer potential of natural peptides from terrestrial and marine environments: A review

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Non-Canonical Amino Acids as Building Blocks for Peptidomimetics: Structure, Function, and Applications

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p‐Nitrobenzyloxycarbonyl (pNZ) as a Temporary Nα‐Protecting Group in Orthogonal Solid‐Phase Peptide Synthesis – Avoiding Diketopiperazine and Aspartimide Formation

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Branched BBB-shuttle peptides: chemoselective modification of proteins to enhance blood–brain barrier transport

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Inhibition of NF-κB Activation by Peptides Targeting NF-κB Essential Modulator (NEMO) Oligomerization

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A novel cell-penetrating peptide suppresses breast tumorigenesis by inhibiting β-catenin/LEF-1 signaling

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Peptibodies: An elegant solution for a long‐standing problem

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Chaperonin Containing TCP-1 Protein Level in Breast Cancer Cells Predicts Therapeutic Application of a Cytotoxic Peptide

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In vivo challenges of anti-diabetic peptide therapeutics: Gastrointestinal stability, toxicity and allergenicity

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Tau Aggregation Inhibiting Peptides as Potential Therapeutics for Alzheimer Disease

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Abbreviated nomenclature for cyclic and branched homo‐ and hetero‐detic peptides

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Lipid Bilayer Crossing—The Gate of Symmetry. Water-Soluble Phenylproline-Based Blood-Brain Barrier Shuttles

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Selection and Characterization of Tau Binding ᴅ-Enantiomeric Peptides with Potential for Therapy of Alzheimer Disease

Dammers, C., Yolcu, D., Kukuk, L., Willbold, D., Pickhardt, M., Mandelkow�, E., Horn, A. H. C., Sticht, H., Malhis, M., Will, N., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0167432 · Cited by 48 · see citing works

Peptipedia: a user-friendly web application and a comprehensive database for peptide research supported by Machine Learning approach

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The CT20 peptide causes detachment and death of metastatic breast cancer cells by promoting mitochondrial aggregation and cytoskeletal disruption

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Modification of Antimicrobial Peptide with Low Molar Mass Poly(ethylene glycol)

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Biomimetic interfaces based on S-layer proteins, lipid membranes and functional biomolecules

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Sequence segregation improves non-covalent protein delivery

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Ribosomally synthesized peptides from natural sources

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Retro‐Enantio N‐Methylated Peptides as β‐Amyloid Aggregation Inhibitors

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Micro OS-ELISA: Rapid noncompetitive detection of a small biomarkerpeptide by open-sandwich enzyme-linked immunosorbent assay (OS-ELISA) integrated into microfluidic device

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A Synthetic 15-mer Peptide (PCK3145) Derived from Prostate Secretory Protein Can Reduce Tumor Growth, Experimental Skeletal Metastases, and Malignancy-Associated Hypercalcemia

Shukeir, N., Arakelian, A., Chen, G., Garde, S. V., Ruiz, M. T., Panchal, C. J., & Rabbani, S. A. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-0788 · Cited by 40 · see citing works

Analysis of peptides and proteins using sub-2μm fully porous and sub 3-μm shell particles

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Molecular design and synthesis of self-assembling camptothecin drug amphiphiles

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Expression of SMAP-29 cathelicidin-like peptide in bacterial cells by intein-mediated system

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Strategies for identifying synthetic peptides to act as inhibitors of NADPH oxidases, or “All that you did and did not want to know about Nox inhibitory peptides”

Dahan, I. M., & Pick, E. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-1007-4 · Cited by 36 · see citing works

Identification of New Peptide Ligands for Epidermal Growth Factor Receptor Using Phage Display and Computationally Modeling their Mode of Binding

Hamzeh‐Mivehroud, M., Mahmoudpour, A., & Dastmalchi, S. (2011) · Chemical Biology & Drug Design · doi:10.1111/j.1747-0285.2011.01282.x · Cited by 35 · see citing works

Enhancing adsorption capacity while maintaining specific recognition performance of mesoporous silica: a novel imprinting strategy with amphiphilic ionic liquid as surfactant

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HER2-Targeted Hybrid Peptide That Blocks HER2 Tyrosine Kinase Disintegrates Cancer Cell Membrane and Inhibits Tumor Growth In Vivo

Kawamoto, M., Horibe, T., Kohno, M., & Kawakami, K. (2013) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-12-0357 · Cited by 35 · see citing works

The inhibitory effects of a RANKL-binding peptide on articular and periarticular bone loss in a murine model of collagen-induced arthritis: a bone histomorphometric study

Kato, G., Shimizu, Y., Arai, Y., Suzuki, N., Sugamori, Y., Maeda, M., Takahashi, M., Tamura, Y., Wakabayashi, N., Murali, R., et al. (2015) · Arthritis Research & Therapy · doi:10.1186/s13075-015-0753-8 · Cited by 35 · see citing works

The yeast two-hybrid system and its role in drug discovery

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A single replacement of histidine to arginine in EGFR-lytic hybrid peptide demonstrates the improved anticancer activity

Tada, N., Horibe, T., Haramoto, M., Ohara, K., Kohno, M., & Kawakami, K. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.03.030 · Cited by 34 · see citing works

Preparation of surface-imprinted microspheres using ionic liquids as novel cross-linker for recognizing an immunostimulating peptide

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Peptides to Tackle Leishmaniasis: Current Status and Future Directions

Robles-Loaiza, A. A., Pinos-Tamayo, E. A., Mendes, B. D. S., Teixeira, C. A. S., Alves, C., Gomes, P. A. C., & Almeida, J. R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094400 · Cited by 32 · see citing works

Amphipathic tail-anchoring peptide is a promising therapeutic agent for prostate cancer treatment

De, G., Ko, J., Tan, T., Hua Zhu, C., Li, H., & Ma, J. (2014) · Oncotarget · doi:10.18632/oncotarget.2301 · Cited by 32 · see citing works

Improving the Stability of α-Conotoxin AuIB Through N-to-C Cyclization: The Effect of Linker Length on Stability and Activity at Nicotinic Acetylcholine Receptors

Armishaw, C. J., Jensen, A. A., Balle, L. D., Scott, K. C. M., Sørensen, L., & Strømgaard, K. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2010.3458 · Cited by 32 · see citing works

Non-natural Amino Acids Containing Peptide-Capped Gold Nanoparticles for Drug Delivery Application

Parween, S., Ali, A., & Chauhan, V. S. (2013) · ACS Applied Materials & Interfaces · doi:10.1021/am4017973 · Cited by 31 · see citing works

Preparation of Sugar Amino Acids by Claisen‐Johnson Rearrangement: Synthesis and Incorporation into Enkephalin Analogues

Montero, A., Mann, E., & Herradón, B. (2004) · European Journal of Organic Chemistry · doi:10.1002/ejoc.200400166 · Cited by 31 · see citing works

Design of a Hyperstable Protein by Rational Consideration of Unfolded State Interactions

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The Overman rearrangement in carbohydrate chemistry: stereoselective synthesis of functionalized 3-amino-3,6-dihydro-2H-pyrans and incorporation in peptide derivatives

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Peptipedia v2.0: a peptide sequence database and user-friendly web platform. A major update

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Differently Selected d -Enantiomeric Peptides Act on Different Aβ Species

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Characterization of a Proteolytically Stable D-Peptide That Suppresses Herpes Simplex Virus 1 Infection: Implications for the Development of Entry-Based Antiviral Therapy

Jaishankar, D., Yakoub, A. M., Bogdanov, A., Vályi-Nagy, T., & Shukla, D. (2014) · Journal of Virology · doi:10.1128/jvi.02979-14 · Cited by 26 · see citing works

Bioactive Synthetic Peptides for Oral Tissues Regeneration

Bermúdez, M., Hoz, L., Montoya, G. A., Campos, M. N., Pérez‐Soria, A., Romo, E., Soto‐Barreras, U., Garnica-Palazuelos, J. C., Aguilar‐Medina, M., Ramos‐Payán, R., et al. (2021) · Frontiers in Materials · doi:10.3389/fmats.2021.655495 · Cited by 26 · see citing works

High expression of apoptosis protein (Api-5) in chemoresistant triple-negative breast cancers: an innovative target

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Alzheimer’s Disease: Challenges and a Therapeutic Opportunity to Treat It with a Neurotrophic Compound

Baazaoui, N., & Iqbal, K. (2022) · Biomolecules · doi:10.3390/biom12101409 · Cited by 24 · see citing works

Peptides in Dentistry: A Scoping Review

Hardan, L., Chedid, J. C. A., Bourgi, R., Cuevas‐Suárez, C. E., Łukomska−Szymańska, M., Tosco, V., Avila, A. J. M., Jabra, M., Salloum-Yared, F., Kharouf, N., et al. (2023) · Bioengineering · doi:10.3390/bioengineering10020214 · Cited by 24 · see citing works

Direct Quantitative Analysis of a 20 kDa PEGylated Human Calcitonin Gene Peptide Antagonist in Cynomolgus Monkey Serum Using In-Source CID and UPLC-MS/MS

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Novel Short Peptides Isolated From Phage Display Library Inhibit Vascular Endothelial Growth Factor Activity

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Efficacy of human β-casein fragment (54–59) and its synthetic analogue compound 89/215 against Leishmania donovani in hamsters

Sharma, P., Singh, N., Garg, R., Haq, W., & Dube, A. (2004) · Peptides · doi:10.1016/j.peptides.2004.06.011 · Cited by 24 · see citing works

Microneedle-Assisted Skin Permeation by Nontoxic Bioengineerable Gas Vesicle Nanoparticles

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Peptides as Diagnostic, Therapeutic, and Theranostic Tools: Progress and Future Challenges

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Refinement of safety and efficacy of anti-cancer chemotherapeutics by tailoring their site-specific intracellular bioavailability through transporter modulation

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Accommodating fluorinated amino acids in a helical peptide environment

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Liquid-Spray or Dry-Powder Systems for Inhaled Delivery of Peptide and Proteins?

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Surprisingly high stability of the Aβ oligomer eliminating all-d-enantiomeric peptide D3 in media simulating the route of orally administered drugs

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Peptides isolated from animal venom as a platform for new therapeutics for the treatment of Alzheimer's disease

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Protein Language Models and Machine Learning Facilitate the Identification of Antimicrobial Peptides

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Drug and Anti-Viral Peptide Design to Inhibit the Monkeypox Virus by Restricting A36R Protein

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Current development in synthesis of peptide precursors and their biological applications

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Recent Advances in the Synthesis of Peptide Surrogates and Their Biological Applications

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Peptides as therapeutics

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Therapeutic peptides: technological advances driving peptides into development

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Therapeutic peptides: Historical perspectives, current development trends, and future directions

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